propafenone has been researched along with Heart Arrest in 18 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to assess adverse effects of oral propafenone in a large number of pediatric patients." | 5.30 | Safety of oral propafenone in the treatment of arrhythmias in infants and children (European retrospective multicenter study). Working Group on Pediatric Arrhythmias and Electrophysiology of the Association of European Pediatric Cardiologists. ( Janousek, J; Paul, T, 1998) |
| " In 1987, the Cardiac Arrest Study Hamburg (CASH), a prospective, randomized trial, was initiated to compare metoprolol, amiodarone, propafenone, and ICD implantation in patients surviving sudden cardiac death due to documented ventricular tachycardia and/or ventricular fibrillation." | 5.07 | Preliminary results of the Cardiac Arrest Study Hamburg (CASH). CASH Investigators. ( Cappato, R; Kuck, KH; Rüppel, R; Schneider, MA; Siebels, J, 1993) |
| "We document a pediatric case report of death due to a mixed drug overdose of metoprolol and propafenone, along with data regarding serum metoprolol, alfa-hydroxymetoprolol, and propafenone levels." | 3.85 | Lethal suicide attempt with a mixed-drug intoxication of metoprolol and propafenone - A first pediatric case report. ( Grundmann, M; Handlos, P; Kacirova, I; Kolek, M; Urinovska, R; Vyskocilova-Hrudikova, E, 2017) |
| " Both, LG 6-101 and LG 6-102 showed strong antiarrhythmic effects against arrhythmias induced on the fifth day by infusion of aconitine (10 micrograms kg-1 min-1)." | 3.68 | LG 6-101 and LG 6-102, two new propafenone-related antiarrhythmic agents with good oral activity in rats. ( Dittrich, P; Kukovetz, WR; Wascher, TC, 1992) |
| "In 1987, the Cardiac Arrest Study Hamburg (CASH), a prospective, multicenter, randomized controlled study, was started in survivors of sudden cardiac death resulting from documented ventricular tachyarrhythmias." | 2.67 | Implantable cardioverter defibrillator compared with antiarrhythmic drug treatment in cardiac arrest survivors (the Cardiac Arrest Study Hamburg). ( Kuck, KH; Siebels, J, 1994) |
| "The prognosis of cardiac arrest (CA) induced by propafenone intoxication was thought to be very poor." | 1.48 | Full recovery after prolonged resuscitation from cardiac arrest due to propafenone intoxication: A case report. ( Geng, P; Ling, B; Tan, D; Walline, J, 2018) |
| "Severe cardiac effects, including cardiac arrest, are a rare complication of high-dose propafenone intake." | 1.42 | Successful Treatment of Propafenone Intoxication With Intravenous Lipid Emulsion. ( Acara, Ç; Arslan, A; Avcı, S; Bayram, B; Köse, I, 2015) |
| "Sudden cardiac arrest survivors have a high risk of suffering from recurrent arrhythmic events." | 1.32 | Long-term follow-up of sudden cardiac arrest survivors and electrophysiologically guided antiarrhythmic therapy. ( Hennersdorf, MG; Niebch, V; Perings, C; Strauer, BE; Vester, EG; Winter, J, 2003) |
| "This study was designed to assess adverse effects of oral propafenone in a large number of pediatric patients." | 1.30 | Safety of oral propafenone in the treatment of arrhythmias in infants and children (European retrospective multicenter study). Working Group on Pediatric Arrhythmias and Electrophysiology of the Association of European Pediatric Cardiologists. ( Janousek, J; Paul, T, 1998) |
| " The latter, however, was taking antiarrhythmic drugs at a dosage less than that proved to be effective during electropharmacological testing." | 1.27 | [Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation]. ( Delise, P; Di Pede, F; Piccolo, E; Raviele, A, 1984) |
| "Emergency treatment of cardiac arrhythmias was required in 41 newborn and infants aged two days to 9 months (mean 77 days) from July 1977 until September 1981." | 1.27 | [Emergency treatment of arrhythmias in neonates and infants]. ( Eigster, G; Weber, H; Wesselhoeft, H, 1983) |
| "Propafenone is a type 1c antiarrhythmic drug that recently has become available for clinical trials within the United States." | 1.27 | Propafenone ingestion. ( McHugh, TP; Perina, DG, 1987) |
| "In the MVP group, the following arrhythmias were induced: nonsustained polymorphic VT in 10, VF in three, and ventricular flutter in one." | 1.27 | The yield of programmed ventricular stimulation in mitral valve prolapse patients with ventricular arrhythmias. ( Gang, ES; Hamer, A; Mandel, WJ; Oseran, DS; Peter, T; Rosenthal, ME, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X | 1 |
| Yang, Z | 1 |
| Kacirova, I | 1 |
| Grundmann, M | 1 |
| Kolek, M | 1 |
| Vyskocilova-Hrudikova, E | 1 |
| Urinovska, R | 1 |
| Handlos, P | 1 |
| Ling, B | 1 |
| Geng, P | 1 |
| Tan, D | 1 |
| Walline, J | 1 |
| Bayram, B | 2 |
| Köse, I | 1 |
| Avcı, S | 1 |
| Arslan, A | 1 |
| Acara, Ç | 1 |
| Wożakowska-Kapłon, B | 1 |
| Stępień-Walek, A | 1 |
| Dedeoglu, E | 1 |
| Hocaoglu, N | 1 |
| Gazi, E | 1 |
| Hennersdorf, MG | 1 |
| Niebch, V | 1 |
| Vester, EG | 1 |
| Winter, J | 1 |
| Perings, C | 1 |
| Strauer, BE | 1 |
| Patane', S | 1 |
| Marte, F | 1 |
| Di Bella, G | 1 |
| Pugliatti, P | 1 |
| Raviele, A | 1 |
| Di Pede, F | 1 |
| Delise, P | 1 |
| Piccolo, E | 1 |
| Weber, H | 1 |
| Wesselhoeft, H | 1 |
| Eigster, G | 1 |
| Siebels, J | 3 |
| Cappato, R | 2 |
| Rüppel, R | 2 |
| Schneider, MA | 2 |
| Kuck, KH | 3 |
| Gómez-Barrado, JJ | 1 |
| García-Rubira, JC | 1 |
| Turégano Albarrán, S | 1 |
| Pavón García, M | 1 |
| Hidalgo Urbano, R | 1 |
| Montes Ramírez, JM | 1 |
| Cruz Fernández, JM | 1 |
| Janousek, J | 1 |
| Paul, T | 1 |
| Wascher, TC | 1 |
| Dittrich, P | 1 |
| Kukovetz, WR | 1 |
| McHugh, TP | 1 |
| Perina, DG | 1 |
| Rosenthal, ME | 1 |
| Hamer, A | 1 |
| Gang, ES | 1 |
| Oseran, DS | 1 |
| Mandel, WJ | 1 |
| Peter, T | 1 |
3 trials available for propafenone and Heart Arrest
| Article | Year |
|---|---|
ICD versus drugs in cardiac arrest survivors: preliminary results of the Cardiac Arrest Study Hamburg.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Death, Sudden, Cardiac; Defibrillators, Implantable | 1993 |
Implantable cardioverter defibrillator compared with antiarrhythmic drug treatment in cardiac arrest survivors (the Cardiac Arrest Study Hamburg).
Topics: Amiodarone; Anti-Arrhythmia Agents; Death, Sudden, Cardiac; Defibrillators, Implantable; Female; Hea | 1994 |
Preliminary results of the Cardiac Arrest Study Hamburg (CASH). CASH Investigators.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Death, Sudden, Cardiac; Defibrillators, Implantable | 1993 |
15 other studies available for propafenone and Heart Arrest
| Article | Year |
|---|---|
Successful treatment of propafenone-induced cardiac arrest by calcium gluconate.
Topics: Adult; Anti-Arrhythmia Agents; Calcium Gluconate; Cardiopulmonary Resuscitation; Drug Overdose; Hear | 2017 |
Lethal suicide attempt with a mixed-drug intoxication of metoprolol and propafenone - A first pediatric case report.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Anti-Arrhythmia Agents; Brain Edema; Cerebral He | 2017 |
Full recovery after prolonged resuscitation from cardiac arrest due to propafenone intoxication: A case report.
Topics: Adult; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Cardiotoxicity; Female; Heart Arrest; | 2018 |
Successful Treatment of Propafenone Intoxication With Intravenous Lipid Emulsion.
Topics: Adult; Anti-Arrhythmia Agents; Drug Overdose; Electrocardiography; Fat Emulsions, Intravenous; Femal | 2015 |
Propafenone overdose: cardiac arrest and full recovery.
Topics: Adolescent; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiopulmonary Resuscitation; Cardi | 2010 |
Propafenone-induced cardiac arrest: full recovery with insulin, is it possible?
Topics: Adolescent; Anti-Arrhythmia Agents; Antidotes; Cardiopulmonary Resuscitation; Combined Modality Ther | 2013 |
Long-term follow-up of sudden cardiac arrest survivors and electrophysiologically guided antiarrhythmic therapy.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Electrophysiologic Tec | 2003 |
Atrial fibrillation, pharmacological cardioversion and topical ophthalmic beta-blocker use.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; C | 2008 |
[Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation].
Topics: Adult; Aged; Amiodarone; Death, Sudden; Disopyramide; Drug Therapy, Combination; Electrocardiography | 1984 |
[Emergency treatment of arrhythmias in neonates and infants].
Topics: Arrhythmias, Cardiac; Bradycardia; Critical Care; Female; Heart Arrest; Heart Block; Heart Defects, | 1983 |
[Circulatory arrest after combined intravenous drugs for the treatment of orthodromic circular tachycardia of Wolff-Parkinson-White syndrome].
Topics: Amiodarone; Anti-Arrhythmia Agents; Drug Therapy, Combination; Female; Heart Arrest; Humans; Middle | 1997 |
Safety of oral propafenone in the treatment of arrhythmias in infants and children (European retrospective multicenter study). Working Group on Pediatric Arrhythmias and Electrophysiology of the Association of European Pediatric Cardiologists.
Topics: Administration, Oral; Adolescent; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Child, Presch | 1998 |
LG 6-101 and LG 6-102, two new propafenone-related antiarrhythmic agents with good oral activity in rats.
Topics: Aconitine; Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biological A | 1992 |
Propafenone ingestion.
Topics: Bundle-Branch Block; Child, Preschool; Electrocardiography; Emergencies; Heart Arrest; Heart Block; | 1987 |
The yield of programmed ventricular stimulation in mitral valve prolapse patients with ventricular arrhythmias.
Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Electrocardiography; Electrophysiology; Female; Heart Arres | 1985 |