Page last updated: 2024-11-03

propafenone and Extrasystole, Ventricular

propafenone has been researched along with Extrasystole, Ventricular in 14 studies

Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.

Research Excerpts

ExcerptRelevanceReference
"To determine the effect of CYP2D6*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia."7.71Effect of CYP2D6*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia. ( Cai, WM; Chen, B; Huang, YZ; Xu, J; Zhang, FM; Zhang, YD, 2002)
"To determine the effect of CYP2D6*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia."3.71Effect of CYP2D6*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia. ( Cai, WM; Chen, B; Huang, YZ; Xu, J; Zhang, FM; Zhang, YD, 2002)
" The dosage from 50 to 100 mg/day made no difference."2.68Preliminary study of the effects of metoprolol and propafenone on ventricular arrhythmia with positive ventricular late potential. ( Duan, Y; Gao, E; Li, H; Yang, C; Zhou, Y, 1997)
"However, in some cases the presence of ventricular ectopic beats indicates susceptibility towards life-threatening arrhythmias or ventricular dysfunction."2.46[When and how to treat ventricular ectopic beats]. ( D'Este, D; Sorbo, MD, 2010)
"Flecainide was the most effective AAD in the achievement of complete/near complete or significant PVC burden reduction, compared to propafenone and sotalol."1.91Idiopathic premature ventricular complexes treatment: Comparison of flecainide, propafenone, and sotalol. ( Bukumirić, Z; Jurčević, R; Kojić, D; Marić, M; Radunović, A; Rajsic, S; Sušić, M; Tomović, M; Žugić, V, 2023)
"A coincidence between intermittent esophageal dysphagia and cardiac arrhythmia, frequent premature ventricular complexes (PVC) were confirmed by clinical observation, simultaneous ECG monitoring, and motility study."1.36High-resolution esophageal manometry with ECG monitoring for management of premature ventricular complexes-associated dysphagia. ( Kalin, K; Kulakowski, P; Sikora, K; Stec, S; Tarnowski, W, 2010)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (21.43)18.2507
2000's2 (14.29)29.6817
2010's8 (57.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Kojić, D1
Radunović, A1
Bukumirić, Z1
Rajsic, S1
Sušić, M1
Marić, M1
Žugić, V1
Jurčević, R1
Tomović, M1
Hyman, MC1
Mustin, D1
Supple, G1
Schaller, RD1
Santangeli, P1
Arkles, J1
Lin, D1
Muser, D1
Dixit, S1
Nazarian, S1
Epstein, AE1
Callans, DJ1
Marchlinski, FE1
Frankel, DS2
Capucci, A1
Ciliberti, G1
Guerra, F1
Stec, S2
Tarnowski, W1
Kalin, K1
Sikora, K1
Kulakowski, P1
D'Este, D1
Sorbo, MD1
Hasdemir, C1
Musayev, O1
Kehribar, DY1
Kartal, Y1
Can, LH1
Pytkowski, M1
Sikorska, A1
Zaborska, B1
Kryński, T1
Szymot, J1
Kułakowski, P1
Cai, WM1
Xu, J1
Chen, B1
Zhang, FM1
Huang, YZ1
Zhang, YD1
Mondillo, S1
Faglia, S1
D'Aprile, N1
Mangiacotti, L1
Campolo, MA1
Agricola, E1
Palazzuoli, V1
Gao, E1
Yang, C1
Li, H1
Duan, Y1
Zhou, Y1
Wang, X1
Zhang, J1
Shi, D1
Zhou, G1
Saikawa, T1
Niwa, H1
Ito, M1
Ishida, S1
Nakagawa, M1
Maeda, T1
Takeshita, Y1
Takakura, T1
Sakata, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Bipolar Radio-frequency Ablation After Standard Unipolar Approach for Ventricular Arrhythmias Originating From the Base of the Heart. The BiUniVA Prospective Registry[NCT05707637]100 participants (Anticipated)Observational [Patient Registry]2022-11-02Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for propafenone and Extrasystole, Ventricular

ArticleYear
[When and how to treat ventricular ectopic beats].
    Giornale italiano di cardiologia (2006), 2010, Volume: 11, Issue:10 Suppl 1

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Encainide; Exercise Test; Humans;

2010

Trials

5 trials available for propafenone and Extrasystole, Ventricular

ArticleYear
Benign symptomatic premature ventricular complexes: short- and long-term efficacy of antiarrhythmic drugs and radiofrequency ablation.
    Kardiologia polska, 2012, Volume: 70, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Arrhythmia Agents; Catheter Ablation; Cross-Over

2012
[Therapy of arrhythmia induced by myocardial ischemia. Association of L-carnitine, propafenone and mexiletine].
    La Clinica terapeutica, 1995, Volume: 146, Issue:12

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Carnitine; Drug Sy

1995
Preliminary study of the effects of metoprolol and propafenone on ventricular arrhythmia with positive ventricular late potential.
    Chinese medical journal, 1997, Volume: 110, Issue:9

    Topics: Adult; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; P

1997
Clinical observation on 84 cases of ventricular premature beat with deficiency syndrome treated by qi lu tang.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1998, Volume: 18, Issue:2

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Disease; Drugs, Chinese Herbal; Female; Humans; Male;

1998
The effect of propafenone on premature ventricular contractions (PVC): an analysis based on heart rate dependency of PVCs.
    Japanese heart journal, 2001, Volume: 42, Issue:6

    Topics: Aged; Anti-Arrhythmia Agents; Electrocardiography, Ambulatory; Electrophysiology; Female; Heart Rate

2001

Other Studies

8 other studies available for propafenone and Extrasystole, Ventricular

ArticleYear
Idiopathic premature ventricular complexes treatment: Comparison of flecainide, propafenone, and sotalol.
    Clinical cardiology, 2023, Volume: 46, Issue:10

    Topics: Anti-Arrhythmia Agents; Electrocardiography; Flecainide; Humans; Propafenone; Retrospective Studies;

2023
Class IC antiarrhythmic drugs for suspected premature ventricular contraction-induced cardiomyopathy.
    Heart rhythm, 2018, Volume: 15, Issue:2

    Topics: Anti-Arrhythmia Agents; Cardiomyopathies; Echocardiography; Electrocardiography; Female; Flecainide;

2018
Reply to the Editor- Flecainide and Propafenone: Good twins for premature ventricular contractions' killing but not exactly superimposable.
    Heart rhythm, 2018, Volume: 15, Issue:9

    Topics: Anti-Arrhythmia Agents; Electrocardiography; Flecainide; Humans; Propafenone; Ventricular Premature

2018
To the Editor- Flecainide and propafenone: Good twins for premature ventricular contractions' killing but not exactly superimposable.
    Heart rhythm, 2018, Volume: 15, Issue:9

    Topics: Anti-Arrhythmia Agents; Cardiomyopathies; Flecainide; Humans; Propafenone; Ventricular Premature Com

2018
High-resolution esophageal manometry with ECG monitoring for management of premature ventricular complexes-associated dysphagia.
    Dysphagia, 2010, Volume: 25, Issue:1

    Topics: Anti-Arrhythmia Agents; Deglutition Disorders; Drug Monitoring; Electrocardiography; Female; Humans;

2010
Chronic cough and tachycardia-induced cardiomyopathy in a patient with idiopathic frequent, monomorphic premature ventricular contractions.
    Pacing and clinical electrophysiology : PACE, 2013, Volume: 36, Issue:5

    Topics: Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Chronic Disease; Cough; Female; Humans; Propafenone;

2013
[Not so simple procedure in "simple" arrhythmias of ventricular].
    Kardiologia polska, 2012, Volume: 70, Issue:4

    Topics: Anti-Arrhythmia Agents; Catheter Ablation; Female; Humans; Male; Metoprolol; Propafenone; Ventricula

2012
Effect of CYP2D6*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia.
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:11

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cytochrome P-450 CYP2D6; Female; Genotype

2002