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propafenone and Drug Overdose

propafenone has been researched along with Drug Overdose in 16 studies

Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"Propafenone is an anti-arrhythmic drug used in the management of supraventricular and ventricular arrhythmias."5.36Propafenone poisoning--a case report with plasma propafenone concentrations. ( Dargan, PI; Jones, AL; Ludman, A; Ovaska, H; Spencer, EP; Wood, DM, 2010)
"We document a pediatric case report of death due to a mixed drug overdose of metoprolol and propafenone, along with data regarding serum metoprolol, alfa-hydroxymetoprolol, and propafenone levels."3.85Lethal suicide attempt with a mixed-drug intoxication of metoprolol and propafenone - A first pediatric case report. ( Grundmann, M; Handlos, P; Kacirova, I; Kolek, M; Urinovska, R; Vyskocilova-Hrudikova, E, 2017)
"Propafenone is an infrequently used class IC antiarrhythmic drug."2.39Propafenone overdose. ( English, B; Ford, M; Kerns, W, 1994)
"Propafenone is a sodium-channel blocker, class IC antiarrhythmic drug, frequently used to manage supraventricular dysrhythmias, especially atrial fibrillation."1.48Failure of Intracardiac Pacing After Fatal Propafenone Overdose: A Case Report. ( Brkljačić, DD; Bulj, N; Čabrilo, V; Kolačević, M; Manola, Š; Zeljković, I, 2018)
"Severe cardiac effects, including cardiac arrest, are a rare complication of high-dose propafenone intake."1.42Successful Treatment of Propafenone Intoxication With Intravenous Lipid Emulsion. ( Acara, Ç; Arslan, A; Avcı, S; Bayram, B; Köse, I, 2015)
"Propafenone is an uncommonly encountered class IC antidysrhythmic that is a look-alike for the opioid, oxycodone/acetaminophen 5/325."1.37Overdose of propafenone surreptitiously sold as "Percocet". ( Curtis, JA; D'Orazio, JL, 2011)
"Propafenone is an anti-arrhythmic drug used in the management of supraventricular and ventricular arrhythmias."1.36Propafenone poisoning--a case report with plasma propafenone concentrations. ( Dargan, PI; Jones, AL; Ludman, A; Ovaska, H; Spencer, EP; Wood, DM, 2010)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's4 (25.00)29.6817
2010's9 (56.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, X1
Yang, Z1
Kacirova, I1
Grundmann, M1
Kolek, M1
Vyskocilova-Hrudikova, E1
Urinovska, R1
Handlos, P1
Zeljković, I1
Bulj, N1
Kolačević, M1
Čabrilo, V1
Brkljačić, DD1
Manola, Š1
Gil, J1
Marmelo, B1
Abreu, L1
Antunes, H1
Santos, LFD1
Cabral, JC1
Bayram, B2
Köse, I1
Avcı, S1
Arslan, A1
Acara, Ç1
Tsiperfal, A1
Scheibly, K1
Matsuda, K1
Ovaska, H1
Ludman, A1
Spencer, EP1
Wood, DM1
Jones, AL1
Dargan, PI1
D'Orazio, JL1
Curtis, JA1
Wożakowska-Kapłon, B1
Stępień-Walek, A1
Dedeoglu, E1
Hocaoglu, N1
Gazi, E1
Hasdemir, C1
Olukman, M1
Ulucan, C1
Roden, DM1
Unal, S1
Bayrakci, B1
Yasar, U1
Karagoz, T1
Kerns, W1
English, B1
Ford, M1
Eray, O1
Fowler, J1
Schranz, W1
Köppel, C1
Oberdisse, U1
Heinemeyer, G1

Reviews

1 review available for propafenone and Drug Overdose

ArticleYear
Propafenone overdose.
    Annals of emergency medicine, 1994, Volume: 24, Issue:1

    Topics: Adult; Bradycardia; Drug Overdose; Electrocardiography; Heart Block; Humans; Male; Propafenone; Seiz

1994

Other Studies

15 other studies available for propafenone and Drug Overdose

ArticleYear
Successful treatment of propafenone-induced cardiac arrest by calcium gluconate.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:8

    Topics: Adult; Anti-Arrhythmia Agents; Calcium Gluconate; Cardiopulmonary Resuscitation; Drug Overdose; Hear

2017
Lethal suicide attempt with a mixed-drug intoxication of metoprolol and propafenone - A first pediatric case report.
    Forensic science international, 2017, Volume: 278

    Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Anti-Arrhythmia Agents; Brain Edema; Cerebral He

2017
Failure of Intracardiac Pacing After Fatal Propafenone Overdose: A Case Report.
    The Journal of emergency medicine, 2018, Volume: 54, Issue:4

    Topics: Aged; Autopsy; Cardiac Catheters; Cardiac Pacing, Artificial; Consciousness Disorders; Drug Overdose

2018
Propafenone Overdose: From Cardiogenic Shock to Brugada Pattern.
    Arquivos brasileiros de cardiologia, 2018, Volume: 110, Issue:3

    Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Drug Overdose; Electrocardiography; Female; Humans;

2018
Successful Treatment of Propafenone Intoxication With Intravenous Lipid Emulsion.
    Pharmacotherapy, 2015, Volume: 35, Issue:10

    Topics: Adult; Anti-Arrhythmia Agents; Drug Overdose; Electrocardiography; Fat Emulsions, Intravenous; Femal

2015
Can QRS Widening be a result of propafenone overdose?
    Progress in cardiovascular nursing, 2008,Fall, Volume: 23, Issue:4

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Consciousness Disorders; Drug Ove

2008
Propafenone poisoning--a case report with plasma propafenone concentrations.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:1

    Topics: Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Coma; Combined Modality Therapy; Drug

2010
Overdose of propafenone surreptitiously sold as "Percocet".
    The Journal of emergency medicine, 2011, Volume: 41, Issue:2

    Topics: Adolescent; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Labeling; Drug Overdose; Electrocardi

2011
Propafenone overdose: cardiac arrest and full recovery.
    Cardiology journal, 2010, Volume: 17, Issue:6

    Topics: Adolescent; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiopulmonary Resuscitation; Cardi

2010
Propafenone-induced cardiac arrest: full recovery with insulin, is it possible?
    The American journal of emergency medicine, 2013, Volume: 31, Issue:2

    Topics: Adolescent; Anti-Arrhythmia Agents; Antidotes; Cardiopulmonary Resuscitation; Combined Modality Ther

2013
Brugada-type ECG pattern and extreme QRS complex widening with propafenone overdose.
    Journal of cardiovascular electrophysiology, 2006, Volume: 17, Issue:5

    Topics: Adolescent; Bundle-Branch Block; Drug Overdose; Electrocardiography; Female; Heart Conduction System

2006
Successful treatment of propafenone, digoxin and warfarin overdosage with plasma exchange therapy and rifampicin.
    Clinical drug investigation, 2007, Volume: 27, Issue:7

    Topics: Adolescent; Anti-Arrhythmia Agents; Anticoagulants; Bradycardia; Cytochrome P-450 Enzyme System; Dig

2007
Severe propafenone poisoning responded to temporary internal pacemaker.
    Veterinary and human toxicology, 2000, Volume: 42, Issue:5

    Topics: Adult; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Charcoal; Drug Overdose; Gastric Lavag

2000
[Aimed endoscopic gastric lavage after propafenone overdose].
    Deutsche medizinische Wochenschrift (1946), 1991, Oct-11, Volume: 116, Issue:41

    Topics: Drug Overdose; Female; Gastric Lavage; Gastroscopy; Humans; Middle Aged; Propafenone

1991
Clinical course and outcome in class IC antiarrhythmic overdose.
    Journal of toxicology. Clinical toxicology, 1990, Volume: 28, Issue:4

    Topics: Ajmaline; Anti-Arrhythmia Agents; Bicarbonates; Bradycardia; Drug Overdose; Flecainide; Hemoperfusio

1990