propafenone has been researched along with Death, Sudden in 4 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During treatment with the class Ic antiarrhythmic agent propafenone, the drug appeared to cause malignant ventricular tachyarrhythmias in five patients." | 7.67 | Malignant ventricular tachyarrhythmias in association with propafenone treatment. ( Bilgin, Y; Buss, J; Neuss, H; Schlepper, M, 1985) |
| "Noninvasive stress and pharmacologic tests with procainamide and propafenone were studied as methods to identify patients with Wolff-Parkinson-White syndrome (WPW) who would otherwise be judged at risk of sudden death on the basis of electrophysiologic criteria: the shortest RR interval during induced atrial fibrillation less than or equal to 250 ms or accessory pathway anterograde effective refractory period less than or equal to 250 ms." | 3.67 | Stress and pharmacologic tests as methods to identify patients with Wolff-Parkinson-White syndrome at risk of sudden death. ( Brusca, A; Gaita, F; Giustetto, C; Mangiardi, L; Riccardi, R, 1989) |
| "During treatment with the class Ic antiarrhythmic agent propafenone, the drug appeared to cause malignant ventricular tachyarrhythmias in five patients." | 3.67 | Malignant ventricular tachyarrhythmias in association with propafenone treatment. ( Bilgin, Y; Buss, J; Neuss, H; Schlepper, M, 1985) |
| " If side effects intervene that may cause continued therapy to be intolerable, changing the antiarrhythmic agent, as opposed to decreasing the dosage to an ineffective range, may be appropriate." | 1.27 | New directions in antiarrhythmic drug therapy. ( Somberg, JC, 1984) |
| " The latter, however, was taking antiarrhythmic drugs at a dosage less than that proved to be effective during electropharmacological testing." | 1.27 | [Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation]. ( Delise, P; Di Pede, F; Piccolo, E; Raviele, A, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Somberg, JC | 1 |
| Raviele, A | 1 |
| Di Pede, F | 1 |
| Delise, P | 1 |
| Piccolo, E | 1 |
| Gaita, F | 1 |
| Giustetto, C | 1 |
| Riccardi, R | 1 |
| Mangiardi, L | 1 |
| Brusca, A | 1 |
| Buss, J | 1 |
| Neuss, H | 1 |
| Bilgin, Y | 1 |
| Schlepper, M | 1 |
4 other studies available for propafenone and Death, Sudden
| Article | Year |
|---|---|
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benz | 1984 |
[Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation].
Topics: Adult; Aged; Amiodarone; Death, Sudden; Disopyramide; Drug Therapy, Combination; Electrocardiography | 1984 |
Stress and pharmacologic tests as methods to identify patients with Wolff-Parkinson-White syndrome at risk of sudden death.
Topics: Adolescent; Adult; Child; Death, Sudden; Exercise Test; Female; Humans; Male; Middle Aged; Procainam | 1989 |
Malignant ventricular tachyarrhythmias in association with propafenone treatment.
Topics: Adult; Aged; Arrhythmias, Cardiac; Death, Sudden; Electrocardiography; Humans; Male; Middle Aged; Pr | 1985 |