propafenone has been researched along with Constitutional Liver Dysfunction in 1 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with Gilbert's syndrome who is also PM participated in an interaction study with propafenone and rifampicin along with five otherwise healthy PMs." | 1.31 | Disposition of propafenone in a poor metabolizer of CYP2D6 with Gilbert's syndrome. ( Dilger, K; Eichelbaum, M; Hofmann, U; Meisel, P, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dilger, K | 1 |
| Meisel, P | 1 |
| Hofmann, U | 1 |
| Eichelbaum, M | 1 |
1 other study available for propafenone and Constitutional Liver Dysfunction
| Article | Year |
|---|---|
Disposition of propafenone in a poor metabolizer of CYP2D6 with Gilbert's syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Cytochrome P-450 CYP2D6; Female; Gilbert Disease; Glucuronosyltransfe | 2000 |