propafenone has been researched along with Complication, Postoperative in 16 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the efficacy of propafenone in preventing atrial tachyarrhythmias after cardiac surgery, and the possible relationships between CYP2D6 polymorphism and the efficacy, pharmacokinetics, and tolerability of propafenone." | 9.13 | Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery: a randomized, double-blind placebo-controlled trial. ( Bail, D; Böhm, JO; Delabar, U; Drescher, S; Eichelbaum, M; Engel, C; Fux, R; Gleiter, CH; Hellberg, KD; Hofmann, U; Igel, S; Jägle, C; Kivistö, KT; Marx, C; Meisner, C; Mörike, K; Rein, JG; Schaeffeler, E; Schwab, M; Wagner, F; Ziemer, G, 2008) |
| "The safety and efficacy of amiodarone and propafenone in converting atrial fibrillation or flutter after cardiac surgery were compared in a randomized double-blind trial." | 9.08 | Intravenous amiodarone vs propafenone for atrial fibrillation and flutter after cardiac operation. ( Cappiello, E; Di Biasi, P; Mangini, A; Paje, A; Santoli, C; Scrofani, R, 1995) |
| "We describe a case of 1:1 atrial flutter in a patient with coronary disease taking propafenone." | 7.70 | Atrial flutter with 1:1 atrioventricular conduction caused by propafenone. ( Adams, PC; el-Harari, MB, 1998) |
| "Propafenone is a sodium channel blocking agent with a mild beta- and calcium channel-blocking activity." | 6.39 | Guidelines for the use of propafenone in treating supraventricular arrhythmias. ( Camm, AJ; Kishore, AG, 1995) |
| "We studied the efficacy of propafenone in preventing atrial tachyarrhythmias after cardiac surgery, and the possible relationships between CYP2D6 polymorphism and the efficacy, pharmacokinetics, and tolerability of propafenone." | 5.13 | Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery: a randomized, double-blind placebo-controlled trial. ( Bail, D; Böhm, JO; Delabar, U; Drescher, S; Eichelbaum, M; Engel, C; Fux, R; Gleiter, CH; Hellberg, KD; Hofmann, U; Igel, S; Jägle, C; Kivistö, KT; Marx, C; Meisner, C; Mörike, K; Rein, JG; Schaeffeler, E; Schwab, M; Wagner, F; Ziemer, G, 2008) |
| "The safety and efficacy of amiodarone and propafenone in converting atrial fibrillation or flutter after cardiac surgery were compared in a randomized double-blind trial." | 5.08 | Intravenous amiodarone vs propafenone for atrial fibrillation and flutter after cardiac operation. ( Cappiello, E; Di Biasi, P; Mangini, A; Paje, A; Santoli, C; Scrofani, R, 1995) |
| "We describe a case of 1:1 atrial flutter in a patient with coronary disease taking propafenone." | 3.70 | Atrial flutter with 1:1 atrioventricular conduction caused by propafenone. ( Adams, PC; el-Harari, MB, 1998) |
| "Propafenone was given to Group 1 (G1); sotalol to Group 2 (G2); amiodarone to Group 3 (G3) and diltiazem to Group 4 (G4) at doses of 300 mg/day, 80 mg/day, 400 mg/day and 180 mg/day orally respectively." | 2.73 | [The comparison between the efficiency of different anti-arrhythmic agents in preventing postoperative atrial fibrillation after open heart surgery]. ( Aytekin, S; Aytekin, V; Men, EE; Tuğcu, A; Yildirimtürk, O, 2008) |
| "Many patients with paroxysmal atrial fibrillation (AF) become refractory to antiarrhythmic drugs (AADs)." | 2.71 | Hybrid therapy with right atrial catheter ablation and previously ineffective antiarrhythmic drugs for the management of atrial fibrillation. ( Block, JE; Calkins, H; Cher, D; Kocheril, AG; Sharma, AD; Stubbs, HA, 2005) |
| "Propafenone is a sodium channel blocking agent with a mild beta- and calcium channel-blocking activity." | 2.39 | Guidelines for the use of propafenone in treating supraventricular arrhythmias. ( Camm, AJ; Kishore, AG, 1995) |
| "To evaluate treatment of junctional ectopic tachycardia after cardiac surgery." | 1.31 | [The treatment of postoperative junctional ectopic tachycardia]. ( Cabrera Duro, A; Galdeano Miranda, JM; Macua Biurrun, P; Martínez Corrales, P; Pastor Menchaca, E; Pilar Orive, J; Rodrigo Carbonero, D, 2002) |
| "Postoperative junctional ectopic tachycardia is associated with a poor prognosis in patients after open-heart surgery." | 1.29 | [Therapy of postoperative ectopic junctional tachycardia by surface hypothermia]. ( Kallfelz, HC; Paul, T; Wilken, M; Ziemer, G, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Men, EE | 1 |
| Yildirimtürk, O | 1 |
| Tuğcu, A | 1 |
| Aytekin, V | 1 |
| Aytekin, S | 1 |
| Soucier, R | 1 |
| Silverman, D | 1 |
| Abordo, M | 1 |
| Jaagosild, P | 1 |
| Abiose, A | 1 |
| Madhusoodanan, KP | 1 |
| Therrien, M | 1 |
| Lippman, N | 1 |
| Dalamagas, H | 1 |
| Berns, E | 1 |
| Lee, JK | 1 |
| Klein, GJ | 1 |
| Krahn, AD | 1 |
| Yee, R | 1 |
| Zarnke, K | 1 |
| Simpson, C | 1 |
| Skanes, A | 1 |
| Kocheril, AG | 1 |
| Calkins, H | 1 |
| Sharma, AD | 1 |
| Cher, D | 1 |
| Stubbs, HA | 1 |
| Block, JE | 1 |
| Mörike, K | 1 |
| Kivistö, KT | 1 |
| Schaeffeler, E | 1 |
| Jägle, C | 1 |
| Igel, S | 1 |
| Drescher, S | 1 |
| Fux, R | 1 |
| Marx, C | 1 |
| Hofmann, U | 1 |
| Engel, C | 1 |
| Wagner, F | 1 |
| Delabar, U | 1 |
| Meisner, C | 1 |
| Bail, D | 1 |
| Böhm, JO | 1 |
| Gleiter, CH | 1 |
| Ziemer, G | 2 |
| Rein, JG | 1 |
| Hellberg, KD | 1 |
| Eichelbaum, M | 1 |
| Schwab, M | 1 |
| Merrick, AF | 1 |
| Odom, NJ | 1 |
| Keenan, DJ | 1 |
| Grotte, GJ | 1 |
| Wilken, M | 1 |
| Paul, T | 1 |
| Kallfelz, HC | 1 |
| Kishore, AG | 1 |
| Camm, AJ | 1 |
| Di Biasi, P | 1 |
| Scrofani, R | 1 |
| Paje, A | 1 |
| Cappiello, E | 1 |
| Mangini, A | 1 |
| Santoli, C | 1 |
| el-Harari, MB | 1 |
| Adams, PC | 1 |
| Cabrera Duro, A | 1 |
| Rodrigo Carbonero, D | 1 |
| Galdeano Miranda, JM | 1 |
| Martínez Corrales, P | 1 |
| Pastor Menchaca, E | 1 |
| Macua Biurrun, P | 1 |
| Pilar Orive, J | 1 |
| Konertz, W | 1 |
| Weyand, M | 1 |
| Deiwick, M | 1 |
| Scheld, HH | 1 |
| Gentili, C | 1 |
| Giordano, F | 1 |
| Alois, A | 1 |
| Massa, E | 1 |
| Bianconi, L | 1 |
| Spes, CH | 1 |
| Angermann, CE | 1 |
| Horn, K | 1 |
| Strasser, T | 1 |
| Mudra, H | 1 |
| Landgraf, R | 1 |
| Theisen, K | 1 |
| Bianchi, G | 1 |
| Manfredonia, A | 1 |
| Lepori, G | 1 |
| Locatelli, A | 1 |
| Di Salvo, F | 1 |
| Garson, A | 1 |
| Moak, JP | 1 |
| Smith, RT | 1 |
| Norton, JB | 1 |
1 review available for propafenone and Complication, Postoperative
| Article | Year |
|---|---|
Guidelines for the use of propafenone in treating supraventricular arrhythmias.
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Surgical Procedure | 1995 |
7 trials available for propafenone and Complication, Postoperative
| Article | Year |
|---|---|
[The comparison between the efficiency of different anti-arrhythmic agents in preventing postoperative atrial fibrillation after open heart surgery].
Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Proc | 2008 |
Propafenone versus ibutilide for post operative atrial fibrillation following cardiac surgery: neither strategy improves outcomes compared to rate control alone (the PIPAF study).
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Pro | 2003 |
Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results.
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Atrial Fib | 2003 |
Hybrid therapy with right atrial catheter ablation and previously ineffective antiarrhythmic drugs for the management of atrial fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Combined Modality Therap | 2005 |
Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery: a randomized, double-blind placebo-controlled trial.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cytochrome P-450 CYP2D6; Double-Blind Method; Fem | 2008 |
Comparison of propafenone to atenolol for the prophylaxis of postcardiotomy supraventricular tachyarrhythmias: a prospective trial.
Topics: Adult; Aged; Atenolol; Coronary Artery Bypass; Coronary Disease; Dose-Response Relationship, Drug; D | 1995 |
Intravenous amiodarone vs propafenone for atrial fibrillation and flutter after cardiac operation.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Coronary Disease; Dos | 1995 |
8 other studies available for propafenone and Complication, Postoperative
| Article | Year |
|---|---|
[Therapy of postoperative ectopic junctional tachycardia by surface hypothermia].
Topics: Combined Modality Therapy; Digitalis Glycosides; Electrocardiography, Ambulatory; Heart Conduction S | 1993 |
Atrial flutter with 1:1 atrioventricular conduction caused by propafenone.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atrioventricular Node; Coronary Artery | 1998 |
[The treatment of postoperative junctional ectopic tachycardia].
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Combined Modality Therapy; Female; | 2002 |
Is pretransplant antiarrhythmic drug therapy a risk factor?
Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Cause of Death; Child; Femal | 1992 |
Efficacy of intravenous propafenone in acute atrial fibrillation complicating open-heart surgery.
Topics: Acute Disease; Aged; Atrial Fibrillation; Blood Pressure; Cardiac Output; Cardiac Surgical Procedure | 1992 |
Ciclosporin-propafenone interaction.
Topics: Arrhythmias, Cardiac; Creatinine; Cyclosporins; Drug Interactions; Heart Transplantation; Humans; Ma | 1990 |
[Arrhythmias in the rehabilitation period after myocardial revascularization surgery by aortocoronary bypass. Efficacy of anti-arrhythmia therapy with propafenone].
Topics: Adult; Aged; Arrhythmias, Cardiac; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Myocar | 1986 |
Usefulness of intravenous propafenone for control of postoperative junctional ectopic tachycardia.
Topics: Child, Preschool; Heart Defects, Congenital; Heart Rate; Humans; Infant; Infant, Newborn; Injections | 1987 |