propafenone has been researched along with Cholestasis in 4 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propafenone, three times 150 mg/d over 33 days and two years later at the same dosage over six days, was administered to an 84-year-old man with ventricular extrasystoles (Lown IVa)." | 5.27 | [Cholestasis after antiarrhythmic therapy with propafenone]. ( Berg, PA; Konz, KH; Seipel, L, 1984) |
| "Propafenone, three times 150 mg/d over 33 days and two years later at the same dosage over six days, was administered to an 84-year-old man with ventricular extrasystoles (Lown IVa)." | 1.27 | [Cholestasis after antiarrhythmic therapy with propafenone]. ( Berg, PA; Konz, KH; Seipel, L, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schuff-Werner, P | 1 |
| Kaiser, D | 1 |
| Lüders, CJ | 1 |
| Berg, PA | 2 |
| Konz, KH | 1 |
| Seipel, L | 1 |
| Schüppel, R | 1 |
| Probst, M | 1 |
| Mondardini, A | 1 |
| Pasquino, P | 1 |
| Bernardi, P | 1 |
| Aluffi, E | 1 |
| Tartaglino, B | 1 |
| Mazzucco, G | 1 |
| Bonino, F | 1 |
| Verme, G | 1 |
| Negro, F | 1 |
1 review available for propafenone and Cholestasis
| Article | Year |
|---|---|
Propafenone-induced liver injury: report of a case and review of the literature.
Topics: Aged; Anti-Arrhythmia Agents; Biopsy; Cholestasis; Humans; Liver; Male; Propafenone | 1993 |
3 other studies available for propafenone and Cholestasis
| Article | Year |
|---|---|
[Propafenon-induced cholestatic liver injury--a further example for allergic drug hepatitis (author's transl)].
Topics: Adrenergic beta-Antagonists; Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotrans | 1981 |
[Cholestasis after antiarrhythmic therapy with propafenone].
Topics: Aged; Cardiac Complexes, Premature; Cholestasis; Humans; Lymphocyte Activation; Male; Propafenone; P | 1984 |
Acute cholestatic hepatitis and the sudden rise of the pacing threshold 5 weeks after VVI-pacemaker implantation.
Topics: Acute Disease; Aged; Cardiac Pacing, Artificial; Cholestasis; Electrocardiography; Hepatitis; Humans | 1994 |