propafenone has been researched along with Brugada Syndrome in 13 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Brugada Syndrome: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case of hidden ECG Brugada pattern, revealed after oral propafenone administration in the setting of pharmaceutical atrial fibrillation cardioversion." | 7.77 | Likelihood of Brugada ECG pattern confirmed after propafenone administration for atrial fibrillation cardioversion. ( Dragios, TD; Kyriakides, ZS; Manolis, AG, 2011) |
| "We report a case of ST elevation in right precordial leads compatible with type 1 Brugada syndrome following administration of propafenone in a patient with Wolff-Parkinson-White syndrome who was receiving lithium at concentrations within therapeutic levels." | 7.74 | Brugada type electrocardiographic changes induced by concomitant use of lithium and propafenone in patient with Wolff-Parkinson-White syndrome. ( Fragakis, N; Iliadis, I; Katsaris, G; Lambrou, A; Papanastasiou, S, 2007) |
| " The case history is reported of a patient with atrial flutter and atrial fibrillation who developed Brugada-like ECG changes when treated with propafenone." | 7.74 | Propafenone-induced Brugada-like ECG changes mistaken as acute myocardial infarction. ( Chutani, S; Grubb, B; Imran, N; Kanjwal, Y, 2008) |
| "Brugada syndrome is associated with sudden cardiac death in patients with a structurally normal heart." | 5.39 | Is a drug-challenge test with propafenone adequate to exclude Brugada syndrome? ( Akilli, A; Bilgin, M; Gul, I; Gungor, H; Yildiz, BS; Zoghi, M, 2013) |
| "Spontaneous monomorphic and polymorphic ventricular tachycardias (VT) were observed during monitoring." | 5.33 | Monomorphic and propafenone-induced polymorphic ventricular tachycardia in Brugada syndrome: a case report. ( Dinckal, MH; Karaca, M, 2006) |
| " We report a case of hidden ECG Brugada pattern, revealed after oral propafenone administration in the setting of pharmaceutical atrial fibrillation cardioversion." | 3.77 | Likelihood of Brugada ECG pattern confirmed after propafenone administration for atrial fibrillation cardioversion. ( Dragios, TD; Kyriakides, ZS; Manolis, AG, 2011) |
| "We report a case of ST elevation in right precordial leads compatible with type 1 Brugada syndrome following administration of propafenone in a patient with Wolff-Parkinson-White syndrome who was receiving lithium at concentrations within therapeutic levels." | 3.74 | Brugada type electrocardiographic changes induced by concomitant use of lithium and propafenone in patient with Wolff-Parkinson-White syndrome. ( Fragakis, N; Iliadis, I; Katsaris, G; Lambrou, A; Papanastasiou, S, 2007) |
| " The case history is reported of a patient with atrial flutter and atrial fibrillation who developed Brugada-like ECG changes when treated with propafenone." | 3.74 | Propafenone-induced Brugada-like ECG changes mistaken as acute myocardial infarction. ( Chutani, S; Grubb, B; Imran, N; Kanjwal, Y, 2008) |
| "Brugada syndrome is an inherited arrhythmogenic disease that may cause sudden cardiac death due to ventricular fibrillation in young adults." | 1.46 | Brugada-Phenocopy Induced by Propafenone Overdose and Successful Treatment: A Case Report. ( Arı, ME; Ekici, F, 2017) |
| "Brugada syndrome is a form of inherited arrhythmia syndrome characterized by a distinct ST-segment elevation in the right precordial leads." | 1.46 | Brugada syndrome, Brugada phenocopy or none? ( Baranchuk, A; Hasdemir, C; Kaya, E; Kocabas, U; Turkoglu, C, 2017) |
| "Brugada syndrome is associated with sudden cardiac death in patients with a structurally normal heart." | 1.39 | Is a drug-challenge test with propafenone adequate to exclude Brugada syndrome? ( Akilli, A; Bilgin, M; Gul, I; Gungor, H; Yildiz, BS; Zoghi, M, 2013) |
| "Following propafenone, this type 2 Brugada ECG pattern turned to the coved type 1 Brugada pattern with ST elevation of more than 2 mm." | 1.37 | [Concealed Brugada syndrome that became apparent incidentally during atrial fibrillation therapy]. ( Işılak, Z; Kılıçaslan, F; Tokatlı, A; Yiğiner, O, 2011) |
| "Spontaneous monomorphic and polymorphic ventricular tachycardias (VT) were observed during monitoring." | 1.33 | Monomorphic and propafenone-induced polymorphic ventricular tachycardia in Brugada syndrome: a case report. ( Dinckal, MH; Karaca, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Mowaswes, M | 1 |
| Biton, Y | 1 |
| Belhassen, B | 1 |
| Arı, ME | 1 |
| Ekici, F | 1 |
| Kocabas, U | 1 |
| Hasdemir, C | 1 |
| Kaya, E | 1 |
| Turkoglu, C | 1 |
| Baranchuk, A | 1 |
| Gil, J | 1 |
| Marmelo, B | 1 |
| Abreu, L | 1 |
| Antunes, H | 1 |
| Santos, LFD | 1 |
| Cabral, JC | 1 |
| Yildiz, BS | 1 |
| Gungor, H | 1 |
| Gul, I | 1 |
| Bilgin, M | 1 |
| Zoghi, M | 1 |
| Akilli, A | 1 |
| Steiner, R | 1 |
| Makarovic, S | 1 |
| Makarovic, Z | 1 |
| Bilic-Curcic, I | 1 |
| Pino, R | 1 |
| Sciortino, G | 1 |
| Polizzi, G | 1 |
| Yiğiner, O | 1 |
| Kılıçaslan, F | 1 |
| Tokatlı, A | 1 |
| Işılak, Z | 1 |
| Dragios, TD | 1 |
| Manolis, AG | 1 |
| Kyriakides, ZS | 1 |
| Karaca, M | 1 |
| Dinckal, MH | 1 |
| Fragakis, N | 1 |
| Iliadis, I | 1 |
| Papanastasiou, S | 1 |
| Lambrou, A | 1 |
| Katsaris, G | 1 |
| Chutani, S | 1 |
| Imran, N | 1 |
| Grubb, B | 1 |
| Kanjwal, Y | 1 |
| Jastrzebski, M | 1 |
13 other studies available for propafenone and Brugada Syndrome
| Article | Year |
|---|---|
Type 1 Brugada-Electrocardiogram: A Rare Presentation in a 57-Year-Old Woman with Paroxysmal Atrial Fibrillation Treated with a Therapeutic Dose of Propafenone.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Brugada Syndrome; Clinical Decision-Making; Drug Substi | 2021 |
Brugada-Phenocopy Induced by Propafenone Overdose and Successful Treatment: A Case Report.
Topics: Adolescent; Adolescent Behavior; Anticonvulsants; Brugada Syndrome; Chicago; Electrocardiography; El | 2017 |
Brugada syndrome, Brugada phenocopy or none?
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Diagnosis, Differential; Electrocardiography; Femal | 2017 |
Propafenone Overdose: From Cardiogenic Shock to Brugada Pattern.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Drug Overdose; Electrocardiography; Female; Humans; | 2018 |
Is a drug-challenge test with propafenone adequate to exclude Brugada syndrome?
Topics: Adrenergic beta-Antagonists; Adult; Ajmaline; Anti-Arrhythmia Agents; Brugada Syndrome; Defibrillato | 2013 |
Brugada syndrome and right ventricle morphofunctional abnormalities on echocardiography in young male with family anamnesis of sudden cardiac death.
Topics: Brugada Syndrome; Death, Sudden, Cardiac; Echocardiography; Electrocardiography; Humans; Male; Middl | 2014 |
Brugada-like phenomenon, induced by intravenous propafenone, in a patient with idiopathic fascicular ventricular tachycardia.
Topics: Administration, Intravenous; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Heart Co | 2013 |
[Concealed Brugada syndrome that became apparent incidentally during atrial fibrillation therapy].
Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Brugada Syndrome; Cardiac Electrophysiology; Car | 2011 |
Likelihood of Brugada ECG pattern confirmed after propafenone administration for atrial fibrillation cardioversion.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Brugada Syndrome; Electric Countershock; Electrocardiog | 2011 |
Monomorphic and propafenone-induced polymorphic ventricular tachycardia in Brugada syndrome: a case report.
Topics: Adult; Ajmaline; Anti-Arrhythmia Agents; Brugada Syndrome; Bundle-Branch Block; Defibrillators, Impl | 2006 |
Brugada type electrocardiographic changes induced by concomitant use of lithium and propafenone in patient with Wolff-Parkinson-White syndrome.
Topics: Brugada Syndrome; Electrocardiography; Female; Humans; Lithium Compounds; Middle Aged; Propafenone; | 2007 |
Propafenone-induced Brugada-like ECG changes mistaken as acute myocardial infarction.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Brugada Syndrome; Catheter Ablati | 2008 |
[Ventricular fibrillation and Brugada-like ECG pattern during propafenone treatment].
Topics: Aged; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Humans; Male; Propafenone; Vent | 2008 |