propafenone has been researched along with Brain Edema in 1 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We document a pediatric case report of death due to a mixed drug overdose of metoprolol and propafenone, along with data regarding serum metoprolol, alfa-hydroxymetoprolol, and propafenone levels." | 3.85 | Lethal suicide attempt with a mixed-drug intoxication of metoprolol and propafenone - A first pediatric case report. ( Grundmann, M; Handlos, P; Kacirova, I; Kolek, M; Urinovska, R; Vyskocilova-Hrudikova, E, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kacirova, I | 1 |
| Grundmann, M | 1 |
| Kolek, M | 1 |
| Vyskocilova-Hrudikova, E | 1 |
| Urinovska, R | 1 |
| Handlos, P | 1 |
1 other study available for propafenone and Brain Edema
| Article | Year |
|---|---|
Lethal suicide attempt with a mixed-drug intoxication of metoprolol and propafenone - A first pediatric case report.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Anti-Arrhythmia Agents; Brain Edema; Cerebral He | 2017 |