propafenone has been researched along with Bradycardia in 14 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous bradyarrhythmias or sick sinus syndrome (SSS), and concomitant use of antiarrhythmic drugs were exclusion criteria." | 6.68 | Conversion of recent onset atrial fibrillation with single loading oral dose of propafenone: is in-hospital admission absolutely necessary? ( Alfieri, G; Barone, P; Bernasconi, G; Bonini, W; Botto, GL; Broffoni, T; Ferrari, G; Lombardi, R; Molteni, S, 1996) |
| "Amiodarone and cedilanid may be the proper drugs for the treatment of paroxysmal atrial fibrillation in the elderly." | 3.73 | Drug therapy of paroxysmal atrial fibrillation in the elderly over 75 years old. ( Cao, J; Chen, DY; Zhu, BP, 2006) |
| "A marked increase of chronic atrial pacing threshold resulting in loss of atrial capture, induced by propafenone, is reported in a patient with bradycardia-tachycardia syndrome." | 3.68 | Propafenone induced acute variation of chronic atrial pacing threshold: a case report. ( Boccadamo, R; Montefoschi, N, 1990) |
| "Previous bradyarrhythmias or sick sinus syndrome (SSS), and concomitant use of antiarrhythmic drugs were exclusion criteria." | 2.68 | Conversion of recent onset atrial fibrillation with single loading oral dose of propafenone: is in-hospital admission absolutely necessary? ( Alfieri, G; Barone, P; Bernasconi, G; Bonini, W; Botto, GL; Broffoni, T; Ferrari, G; Lombardi, R; Molteni, S, 1996) |
| "Propafenone is an infrequently used class IC antiarrhythmic drug." | 2.39 | Propafenone overdose. ( English, B; Ford, M; Kerns, W, 1994) |
| "Guidelines recommend that initial trial of a "pill-in-the-pocket" (PIP) Class 1C antiarrhythmic drug (AAD) for cardioversion of atrial fibrillation (AF) be performed in a monitored setting because of the potential for adverse reactions." | 1.72 | Safety of Pill-in-the-Pocket Class 1C Antiarrhythmic Drugs for Atrial Fibrillation. ( Arkles, JS; Callans, DJ; Deo, R; Dixit, S; Epstein, AE; Frankel, DS; Guandalini, GS; Hyman, MC; Jarrah, AA; Lin, D; Marchlinski, FE; Markman, TM; Mustin, E; Nazarian, S; Riley, M; Santangeli, P; Schaller, RD; Supple, GE; Tian, Y, 2022) |
| "Propafenone is a Vaughan Williams class 1c antiarrhythmic medication widely used for treatment of arrhythmias." | 1.46 | Revisiting propafenone toxicity. ( Alsaad, AA; Austin, CO; Kusumoto, F; Ortiz Gonzalez, Y, 2017) |
| "Mirtazapine is a commonly prescribed antidepressant drug, which is also metabolized through and may modulate the CYP4502D6 pathway leading to altered metabolism of propafenone and possible adverse effects." | 1.40 | Propafenone associated severe central nervous system and cardiovascular toxicity due to mirtazapine: a case of severe drug interaction. ( Aryal, SR; Khan, MA; Rajpurohit, N; Stys, AT; Stys, TP, 2014) |
| "Emergency treatment of cardiac arrhythmias was required in 41 newborn and infants aged two days to 9 months (mean 77 days) from July 1977 until September 1981." | 1.27 | [Emergency treatment of arrhythmias in neonates and infants]. ( Eigster, G; Weber, H; Wesselhoeft, H, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Markman, TM | 1 |
| Jarrah, AA | 1 |
| Tian, Y | 1 |
| Mustin, E | 1 |
| Guandalini, GS | 1 |
| Lin, D | 1 |
| Epstein, AE | 1 |
| Hyman, MC | 1 |
| Deo, R | 1 |
| Supple, GE | 1 |
| Arkles, JS | 1 |
| Dixit, S | 1 |
| Schaller, RD | 1 |
| Santangeli, P | 1 |
| Nazarian, S | 1 |
| Riley, M | 1 |
| Callans, DJ | 1 |
| Marchlinski, FE | 1 |
| Frankel, DS | 1 |
| Alsaad, AA | 1 |
| Ortiz Gonzalez, Y | 1 |
| Austin, CO | 1 |
| Kusumoto, F | 1 |
| Rajpurohit, N | 1 |
| Aryal, SR | 1 |
| Khan, MA | 1 |
| Stys, AT | 1 |
| Stys, TP | 1 |
| Chen, DY | 1 |
| Cao, J | 1 |
| Zhu, BP | 1 |
| Unal, S | 1 |
| Bayrakci, B | 1 |
| Yasar, U | 1 |
| Karagoz, T | 1 |
| Weber, H | 1 |
| Wesselhoeft, H | 1 |
| Eigster, G | 1 |
| Alboni, P | 1 |
| Filippi, L | 1 |
| Pirani, R | 1 |
| Preziosi, S | 1 |
| Paparella, N | 1 |
| Kerns, W | 1 |
| English, B | 1 |
| Ford, M | 1 |
| Botto, GL | 1 |
| Bonini, W | 1 |
| Broffoni, T | 1 |
| Molteni, S | 1 |
| Lombardi, R | 1 |
| Alfieri, G | 1 |
| Barone, P | 1 |
| Bernasconi, G | 1 |
| Ferrari, G | 1 |
| Tucci, PJ | 1 |
| Cicogna, AC | 1 |
| Spadaro, J | 1 |
| Montefoschi, N | 1 |
| Boccadamo, R | 1 |
| Köppel, C | 1 |
| Oberdisse, U | 1 |
| Heinemeyer, G | 1 |
| Lee, PK | 1 |
| Kerr, CR | 1 |
| Vorderbrugge, S | 1 |
| Qi, AZ | 1 |
| Yeung-Lai-Wah, JA | 1 |
| de Lorenzo-Cáceres Ascanio, A | 1 |
| Hernández-Mora, PG | 1 |
| Brezmes Valdivieso, JA | 1 |
| Serrallé Arias de Castro, JR | 1 |
1 review available for propafenone and Bradycardia
| Article | Year |
|---|---|
Propafenone overdose.
Topics: Adult; Bradycardia; Drug Overdose; Electrocardiography; Heart Block; Humans; Male; Propafenone; Seiz | 1994 |
1 trial available for propafenone and Bradycardia
| Article | Year |
|---|---|
Conversion of recent onset atrial fibrillation with single loading oral dose of propafenone: is in-hospital admission absolutely necessary?
Topics: Administration, Oral; Age Factors; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Atr | 1996 |
12 other studies available for propafenone and Bradycardia
| Article | Year |
|---|---|
Safety of Pill-in-the-Pocket Class 1C Antiarrhythmic Drugs for Atrial Fibrillation.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Female; Flecainide; Humans; H | 2022 |
Revisiting propafenone toxicity.
Topics: Aged; Anti-Arrhythmia Agents; Bradycardia; Humans; Hypotension; Male; Propafenone | 2017 |
Propafenone associated severe central nervous system and cardiovascular toxicity due to mirtazapine: a case of severe drug interaction.
Topics: Aged; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Atrial Fibrillation; Bradycardia; Di | 2014 |
Drug therapy of paroxysmal atrial fibrillation in the elderly over 75 years old.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Cardi | 2006 |
Successful treatment of propafenone, digoxin and warfarin overdosage with plasma exchange therapy and rifampicin.
Topics: Adolescent; Anti-Arrhythmia Agents; Anticoagulants; Bradycardia; Cytochrome P-450 Enzyme System; Dig | 2007 |
[Emergency treatment of arrhythmias in neonates and infants].
Topics: Arrhythmias, Cardiac; Bradycardia; Critical Care; Female; Heart Arrest; Heart Block; Heart Defects, | 1983 |
[Electrophysiologic effects of propafenone in patients with sinus node dysfunction].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrioventricular Node; Bradycardia; Female; Heart Block; Heart | 1984 |
[Changes in the mechanical action of the isolated guinea pig heart induced by doses of propafenon capable of affecting the electrocardiogram].
Topics: Animals; Blood Pressure; Bradycardia; Electrocardiography; Guinea Pigs; Heart Conduction System; Hea | 1979 |
Propafenone induced acute variation of chronic atrial pacing threshold: a case report.
Topics: Atrioventricular Node; Bradycardia; Cardiac Pacing, Artificial; Electrocardiography; Female; Humans; | 1990 |
Clinical course and outcome in class IC antiarrhythmic overdose.
Topics: Ajmaline; Anti-Arrhythmia Agents; Bicarbonates; Bradycardia; Drug Overdose; Flecainide; Hemoperfusio | 1990 |
Symptomatic sinus node dysfunction associated with the use of propafenone.
Topics: Bradycardia; Cardiac Pacing, Artificial; Heart Diseases; Humans; Propafenone; Sinoatrial Node; Synco | 1988 |
[Intense symptomatic bradycardia caused by sinoauricular block: severe adverse reaction caused by propafenone].
Topics: Aged; Bradycardia; Heart Block; Humans; Male; Propafenone | 1987 |