propafenone has been researched along with Bradyarrhythmia in 14 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous bradyarrhythmias or sick sinus syndrome (SSS), and concomitant use of antiarrhythmic drugs were exclusion criteria." | 6.68 | Conversion of recent onset atrial fibrillation with single loading oral dose of propafenone: is in-hospital admission absolutely necessary? ( Alfieri, G; Barone, P; Bernasconi, G; Bonini, W; Botto, GL; Broffoni, T; Ferrari, G; Lombardi, R; Molteni, S, 1996) |
| "Amiodarone and cedilanid may be the proper drugs for the treatment of paroxysmal atrial fibrillation in the elderly." | 3.73 | Drug therapy of paroxysmal atrial fibrillation in the elderly over 75 years old. ( Cao, J; Chen, DY; Zhu, BP, 2006) |
| "A marked increase of chronic atrial pacing threshold resulting in loss of atrial capture, induced by propafenone, is reported in a patient with bradycardia-tachycardia syndrome." | 3.68 | Propafenone induced acute variation of chronic atrial pacing threshold: a case report. ( Boccadamo, R; Montefoschi, N, 1990) |
| "Previous bradyarrhythmias or sick sinus syndrome (SSS), and concomitant use of antiarrhythmic drugs were exclusion criteria." | 2.68 | Conversion of recent onset atrial fibrillation with single loading oral dose of propafenone: is in-hospital admission absolutely necessary? ( Alfieri, G; Barone, P; Bernasconi, G; Bonini, W; Botto, GL; Broffoni, T; Ferrari, G; Lombardi, R; Molteni, S, 1996) |
| "Propafenone is an infrequently used class IC antiarrhythmic drug." | 2.39 | Propafenone overdose. ( English, B; Ford, M; Kerns, W, 1994) |
| "Guidelines recommend that initial trial of a "pill-in-the-pocket" (PIP) Class 1C antiarrhythmic drug (AAD) for cardioversion of atrial fibrillation (AF) be performed in a monitored setting because of the potential for adverse reactions." | 1.72 | Safety of Pill-in-the-Pocket Class 1C Antiarrhythmic Drugs for Atrial Fibrillation. ( Arkles, JS; Callans, DJ; Deo, R; Dixit, S; Epstein, AE; Frankel, DS; Guandalini, GS; Hyman, MC; Jarrah, AA; Lin, D; Marchlinski, FE; Markman, TM; Mustin, E; Nazarian, S; Riley, M; Santangeli, P; Schaller, RD; Supple, GE; Tian, Y, 2022) |
| "Propafenone is a Vaughan Williams class 1c antiarrhythmic medication widely used for treatment of arrhythmias." | 1.46 | Revisiting propafenone toxicity. ( Alsaad, AA; Austin, CO; Kusumoto, F; Ortiz Gonzalez, Y, 2017) |
| "Mirtazapine is a commonly prescribed antidepressant drug, which is also metabolized through and may modulate the CYP4502D6 pathway leading to altered metabolism of propafenone and possible adverse effects." | 1.40 | Propafenone associated severe central nervous system and cardiovascular toxicity due to mirtazapine: a case of severe drug interaction. ( Aryal, SR; Khan, MA; Rajpurohit, N; Stys, AT; Stys, TP, 2014) |
| "Emergency treatment of cardiac arrhythmias was required in 41 newborn and infants aged two days to 9 months (mean 77 days) from July 1977 until September 1981." | 1.27 | [Emergency treatment of arrhythmias in neonates and infants]. ( Eigster, G; Weber, H; Wesselhoeft, H, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Markman, TM | 1 |
| Jarrah, AA | 1 |
| Tian, Y | 1 |
| Mustin, E | 1 |
| Guandalini, GS | 1 |
| Lin, D | 1 |
| Epstein, AE | 1 |
| Hyman, MC | 1 |
| Deo, R | 1 |
| Supple, GE | 1 |
| Arkles, JS | 1 |
| Dixit, S | 1 |
| Schaller, RD | 1 |
| Santangeli, P | 1 |
| Nazarian, S | 1 |
| Riley, M | 1 |
| Callans, DJ | 1 |
| Marchlinski, FE | 1 |
| Frankel, DS | 1 |
| Alsaad, AA | 1 |
| Ortiz Gonzalez, Y | 1 |
| Austin, CO | 1 |
| Kusumoto, F | 1 |
| Rajpurohit, N | 1 |
| Aryal, SR | 1 |
| Khan, MA | 1 |
| Stys, AT | 1 |
| Stys, TP | 1 |
| Chen, DY | 1 |
| Cao, J | 1 |
| Zhu, BP | 1 |
| Unal, S | 1 |
| Bayrakci, B | 1 |
| Yasar, U | 1 |
| Karagoz, T | 1 |
| Weber, H | 1 |
| Wesselhoeft, H | 1 |
| Eigster, G | 1 |
| Alboni, P | 1 |
| Filippi, L | 1 |
| Pirani, R | 1 |
| Preziosi, S | 1 |
| Paparella, N | 1 |
| Kerns, W | 1 |
| English, B | 1 |
| Ford, M | 1 |
| Botto, GL | 1 |
| Bonini, W | 1 |
| Broffoni, T | 1 |
| Molteni, S | 1 |
| Lombardi, R | 1 |
| Alfieri, G | 1 |
| Barone, P | 1 |
| Bernasconi, G | 1 |
| Ferrari, G | 1 |
| Tucci, PJ | 1 |
| Cicogna, AC | 1 |
| Spadaro, J | 1 |
| Montefoschi, N | 1 |
| Boccadamo, R | 1 |
| Köppel, C | 1 |
| Oberdisse, U | 1 |
| Heinemeyer, G | 1 |
| Lee, PK | 1 |
| Kerr, CR | 1 |
| Vorderbrugge, S | 1 |
| Qi, AZ | 1 |
| Yeung-Lai-Wah, JA | 1 |
| de Lorenzo-Cáceres Ascanio, A | 1 |
| Hernández-Mora, PG | 1 |
| Brezmes Valdivieso, JA | 1 |
| Serrallé Arias de Castro, JR | 1 |
1 review available for propafenone and Bradyarrhythmia
| Article | Year |
|---|---|
Propafenone overdose.
Topics: Adult; Bradycardia; Drug Overdose; Electrocardiography; Heart Block; Humans; Male; Propafenone; Seiz | 1994 |
1 trial available for propafenone and Bradyarrhythmia
| Article | Year |
|---|---|
Conversion of recent onset atrial fibrillation with single loading oral dose of propafenone: is in-hospital admission absolutely necessary?
Topics: Administration, Oral; Age Factors; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Atr | 1996 |
12 other studies available for propafenone and Bradyarrhythmia
| Article | Year |
|---|---|
Safety of Pill-in-the-Pocket Class 1C Antiarrhythmic Drugs for Atrial Fibrillation.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Female; Flecainide; Humans; H | 2022 |
Revisiting propafenone toxicity.
Topics: Aged; Anti-Arrhythmia Agents; Bradycardia; Humans; Hypotension; Male; Propafenone | 2017 |
Propafenone associated severe central nervous system and cardiovascular toxicity due to mirtazapine: a case of severe drug interaction.
Topics: Aged; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Atrial Fibrillation; Bradycardia; Di | 2014 |
Drug therapy of paroxysmal atrial fibrillation in the elderly over 75 years old.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Cardi | 2006 |
Successful treatment of propafenone, digoxin and warfarin overdosage with plasma exchange therapy and rifampicin.
Topics: Adolescent; Anti-Arrhythmia Agents; Anticoagulants; Bradycardia; Cytochrome P-450 Enzyme System; Dig | 2007 |
[Emergency treatment of arrhythmias in neonates and infants].
Topics: Arrhythmias, Cardiac; Bradycardia; Critical Care; Female; Heart Arrest; Heart Block; Heart Defects, | 1983 |
[Electrophysiologic effects of propafenone in patients with sinus node dysfunction].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrioventricular Node; Bradycardia; Female; Heart Block; Heart | 1984 |
[Changes in the mechanical action of the isolated guinea pig heart induced by doses of propafenon capable of affecting the electrocardiogram].
Topics: Animals; Blood Pressure; Bradycardia; Electrocardiography; Guinea Pigs; Heart Conduction System; Hea | 1979 |
Propafenone induced acute variation of chronic atrial pacing threshold: a case report.
Topics: Atrioventricular Node; Bradycardia; Cardiac Pacing, Artificial; Electrocardiography; Female; Humans; | 1990 |
Clinical course and outcome in class IC antiarrhythmic overdose.
Topics: Ajmaline; Anti-Arrhythmia Agents; Bicarbonates; Bradycardia; Drug Overdose; Flecainide; Hemoperfusio | 1990 |
Symptomatic sinus node dysfunction associated with the use of propafenone.
Topics: Bradycardia; Cardiac Pacing, Artificial; Heart Diseases; Humans; Propafenone; Sinoatrial Node; Synco | 1988 |
[Intense symptomatic bradycardia caused by sinoauricular block: severe adverse reaction caused by propafenone].
Topics: Aged; Bradycardia; Heart Block; Humans; Male; Propafenone | 1987 |