Page last updated: 2024-11-03

propafenone and Atrial Flutter

propafenone has been researched along with Atrial Flutter in 77 studies

Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.

Atrial Flutter: Rapid, irregular atrial contractions caused by a block of electrical impulse conduction in the right atrium and a reentrant wave front traveling up the inter-atrial septum and down the right atrial free wall or vice versa. Unlike ATRIAL FIBRILLATION which is caused by abnormal impulse generation, typical atrial flutter is caused by abnormal impulse conduction. As in atrial fibrillation, patients with atrial flutter cannot effectively pump blood into the lower chambers of the heart (HEART VENTRICLES).

Research Excerpts

ExcerptRelevanceReference
"To investigate the efficacy and safety of intravenous ibutilide for conversion of atrial fibrillation (AF) and flutter (AFL) to sinus rhythm."9.17[Efficacy and safety of ibutilide for conversion of atrial fibrillation/flutter]. ( Ma, C; Xiang, M; Yang, Y; Yu, Z; Zhang, S, 2013)
"We evaluated the safety and efficacy of ibutilide when added to propafenone in treating both paroxysmal and chronic atrial fibrillation (AF) and atrial flutter (AFL)."9.11Ibutilide added to propafenone for the conversion of atrial fibrillation and atrial flutter. ( Chiladakis, JA; Kalogeropoulos, A; Manolis, AS; Patsouras, N, 2004)
"We sought to assess the efficacy and safety of ibutilide cardioversion for those with atrial fibrillation (AF) or atrial flutter (AFL) receiving long-term treatmentwith class IC agents."9.11Use of ibutilide in cardioversion of patients with atrial fibrillation or atrial flutter treated with class IC agents. ( Bonso, A; Glatter, KA; Hongo, RH; Raviele, A; Rossillo, A; Scheinman, MM; Themistoclakis, S; Yang, Y, 2004)
"To evaluate the efficacy and safety of intravenous ibutilide and propafenone for immediate treatment of atrial flutter."9.11Clinical comparison of ibutilide and propafenone for converting atrial flutter. ( Guo, JH; Sun, JL; Zhang, HC; Zhang, N; Zhang, P, 2005)
"To compare the efficacy and safety of ibutilide versus propafenone in immediate cardioversion of atrial fibrillation (AF) and atrial flutter (AFL) lasted less than 90 days."9.11[Immediate cardioversion of atrial fibrillation and atrial flutter lasting less than 90 days by ibutilide versus propafenone: a multicenter study]. ( Fang, Q; Ge, JB; Guo, JH; Guo, JX; Han, SM; Sun, YM; Wan, Z; Zhang, HC; Zheng, YA; Zhu, WQ, 2005)
"This multicentre, randomized, double-blind study, conducted in parallel groups, was designed to compare the efficacy and safety of cibenzoline (C) and oral propafenone (P) in the prevention of recurrent atrial arrhythmias (M) over a 6-month period."9.08[Cibenzoline versus propafenone by the oral route for preventing recurrence of atrial arrhythmia: multicenter, randomized, double-blind study]. ( Bleinc, D; Canler, A; Lardoux, H; Maison Blanche, P; Marchand, X; Péraudeau, P; Rouesnel, P; Scheck, F, 1996)
"Fifty patients with symptomatic type I atrial flutter in whom termination of the arrhythmia with transesophageal stimulation was unsuccessful were randomized to undergo a repeat procedure after intravenous propafenone (n = 25) or placebo (n = 25)."9.08Efficacy of intravenous propafenone in termination of atrial flutter by overdrive transesophageal pacing previously ineffective. ( Bertaglia, E; D'Este, D; Franceschi, M; Mantovan, R; Pascotto, P; Zanocco, A, 1997)
"The results suggest that propafenone produces a more prompt effect in converting patients from atrial fibrillation or flutter to normal sinus rhythm."9.08The efficacy and safety of intravenous propafenone versus intravenous amiodarone in the conversion of atrial fibrillation or flutter after cardiac surgery. ( Larbuisson, R; Stiels, B; Venneman, I, 1996)
"Safety and efficacy of propafenone and disopyramide for long-term maintenance of sinus rhythm after electrical cardioversion was studied in 56 patients with chronic atrial fibrillation (median arrhythmia duration, 5 months)."9.08Propafenone versus disopyramide for maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation: a randomized, double-blind study. PRODIS Study Group. ( Crijns, HJ; Gosselink, AT; Lie, KI, 1996)
"To assess the cardiac and extracardiac safety and efficacy of flecainide versus propafenone in patients suffering from episodes of paroxysmal atrial fibrillation (AF) or atrial flutter, 97 patients were enrolled in a randomized, open-label, long-term, parallel, comparative multicenter study."9.08Comparison of the safety and efficacy of flecainide versus propafenone in hospital out-patients with symptomatic paroxysmal atrial fibrillation/flutter. The Flecainide AF French Study Group. ( Aliot, E; Denjoy, I, 1996)
"The safety and efficacy of amiodarone and propafenone in converting atrial fibrillation or flutter after cardiac surgery were compared in a randomized double-blind trial."9.08Intravenous amiodarone vs propafenone for atrial fibrillation and flutter after cardiac operation. ( Cappiello, E; Di Biasi, P; Mangini, A; Paje, A; Santoli, C; Scrofani, R, 1995)
"Efficacy and safety of intravenous flecainide (2 mg/kg body weight in 10 minutes), verapamil (10 mg in 1 minute), and propafenone (2 mg/kg body weight in 10 minutes) were investigated in 90 consecutive patients with atrial fibrillation (AF) or flutter (AFL)."9.07Acute pharmacologic conversion of atrial fibrillation and flutter: the role of flecainide, propafenone, and verapamil. ( Kingma, JH; Suttorp, MJ, 1992)
"The efficacy of intravenous propafenone (2 mg/kg) was assessed in 83 consecutive patients: 68 with atrial fibrillation (AF) and 15 with atrial flutter lasting less than 15 days."9.06Effectiveness of intravenous propafenone for conversion of atrial fibrillation and flutter of recent onset. ( Bianconi, L; Boccadamo, R; Gentili, C; Pappalardo, A; Pistolese, M, 1989)
"This review summarizes the results of placebo-controlled trials of propafenone, a class IC antiarrhythmic drug, in patients with supraventricular tachycardia, atrial fibrillation (AF), and atrial flutter."8.80Placebo-controlled evaluations of propafenone for atrial tachyarrhythmias. ( Rae, AP, 1998)
"Our objective was to evaluate the efficacy and safety of intravenous (IV) sotalol in the treatment of incessant tachyarrhythmias in children with normal cardiac function."7.85Efficacy of Intravenous Sotalol for Treatment of Incessant Tachyarrhythmias in Children. ( Ge, H; Jiang, H; Li, X; Liu, H; Zhang, Y, 2017)
"We present two cases of proarrhythmia after propafenone treatment."7.74[Proarrhythmic effect of propafenone in patients with atrial fibrillation and atrial flutter]. ( Jastrzebski, M, 2008)
" The case history is reported of a patient with atrial flutter and atrial fibrillation who developed Brugada-like ECG changes when treated with propafenone."7.74Propafenone-induced Brugada-like ECG changes mistaken as acute myocardial infarction. ( Chutani, S; Grubb, B; Imran, N; Kanjwal, Y, 2008)
"The effectiveness and safety of ibutilide (IB) use in patients receiving amiodarone or propafenone for atrial flutter (AFL) and atrial fibrillation (AF) were compared to IB alone."7.73Efficacy and safety of ibutilide for cardioversion of atrial flutter and fibrillation in patients receiving amiodarone or propafenone. ( Fragakis, N; Katsaris, G; Kozirakis, M; Maligkos, G; Papadopoulos, N; Papanastasiou, S; Tsaritsaniotis, E, 2005)
"Among the 136 patients treated for atrial fibrillation with amiodarone (n = 96) or propafenone (n = 40), 15 (11%, mean age 65."7.70Persistent atrial flutter in patients treated for atrial fibrillation with amiodarone and propafenone: electrophysiologic characteristics, radiofrequency catheter ablation, and risk prediction. ( Chang, MS; Chen, SA; Chen, YJ; Chiang, CE; Ding, YA; Feng, AN; Lee, SH; Tai, CT; Yu, WC, 1999)
"We describe a case of 1:1 atrial flutter in a patient with coronary disease taking propafenone."7.70Atrial flutter with 1:1 atrioventricular conduction caused by propafenone. ( Adams, PC; el-Harari, MB, 1998)
"The effects of procainamide and propafenone on the composition of the excitable gap (EG) were studied in a canine model of atrial flutter (AFI) around the tricuspid valve."7.69Effects of procainamide and propafenone on the composition of the excitable gap in canine atrial reentry tachycardia. ( Derakhchan, K; Kus, T; Lambert, C; Pagé, P, 1994)
" In order to prevent/terminate fibrillation propafenone (Rytmonorm, 450-600 mg/day) was started, however this therapy resulted in permanent atrial flutter of 230-270/min mainly with 2:1 antrioventricular conduction."7.69[Persistent atrial flutter induced by propafenone (Rytmonorm)]. ( Fazekas, T; Kiss, J; Pap, I; Rudas, L, 1994)
"0 micrograms/kg, n = 8), a class III drug, on atrial flutter (AF) caused by reentry were compared with those of disopyramide (1."7.68Effects of pentisomide and E-4031 on canine atrial flutter due to reentry: a comparative study with disopyramide and propafenone. ( Inoue, H; Nozaki, A; Saihara, S; Sugimoto, T; Usui, M; Yamashita, T, 1991)
"The safety and efficacy of intravenous Propafenone, in the treatment of atrial fibrillation (a."7.67[Fibrillation and atrial flutter. Immediate control and conversion to sinus rhythm with intravenous propafenone]. ( Bianconi, L; Boccadamo, R; Broglia, R; Pappalardo, A; Pistolese, M, 1987)
"Sixty patients who had recurrent episodes of symptomatic atrial fibrillation or flutter, or both, and who had failed one to five prior drug trials were treated with open label oral propafenone hydrochloride."7.67Long-term oral propafenone therapy for suppression of refractory symptomatic atrial fibrillation and atrial flutter. ( Antman, EM; Beamer, AD; Cantillon, C; Friedman, PL; Goldman, L; McGowan, N, 1988)
"Forty-seven patients with chronic atrial fibrillation and (or) flutter in whom the clinical picture and the length of arrhythmia indicated that drug-mediated cardioversion should be tried were treated with a combination of lidoflazine and propafenon."7.66[Combined use of propafenon and lidoflazine in chronic atrial fibrillation and flutter (author's transl)]. ( Beck, OA; Hochrein, H, 1980)
"Oral propafenone was administered and within 6 hours no further arrhythmias or side effects were noted."5.30Atrial flutter in a pediatric patient in the immediate period after the Fontan procedure: control with oral propafenone. ( Herzberg, GZ; Rossi, AF, 1997)
" Dosage and serum levels of propafenone did not differ whether the patients were treated successfully or not."5.29Clinical experience with propafenone for cardiac arrhythmias in the young. ( Bourgeous, M; Heusch, A; Kramer, HH; Krogmann, ON; Rammos, S, 1994)
"Propafenone was less effective (mean effect 3."5.27European experience with the antiarrhythmic efficacy of propafenone for supraventricular and ventricular arrhythmias. ( Assayag, P; Coumel, P; Leclercq, JF, 1984)
"To investigate the efficacy and safety of intravenous ibutilide for conversion of atrial fibrillation (AF) and flutter (AFL) to sinus rhythm."5.17[Efficacy and safety of ibutilide for conversion of atrial fibrillation/flutter]. ( Ma, C; Xiang, M; Yang, Y; Yu, Z; Zhang, S, 2013)
"We evaluated the safety and efficacy of ibutilide when added to propafenone in treating both paroxysmal and chronic atrial fibrillation (AF) and atrial flutter (AFL)."5.11Ibutilide added to propafenone for the conversion of atrial fibrillation and atrial flutter. ( Chiladakis, JA; Kalogeropoulos, A; Manolis, AS; Patsouras, N, 2004)
"We sought to assess the efficacy and safety of ibutilide cardioversion for those with atrial fibrillation (AF) or atrial flutter (AFL) receiving long-term treatmentwith class IC agents."5.11Use of ibutilide in cardioversion of patients with atrial fibrillation or atrial flutter treated with class IC agents. ( Bonso, A; Glatter, KA; Hongo, RH; Raviele, A; Rossillo, A; Scheinman, MM; Themistoclakis, S; Yang, Y, 2004)
"To evaluate the efficacy and safety of intravenous ibutilide and propafenone for immediate treatment of atrial flutter."5.11Clinical comparison of ibutilide and propafenone for converting atrial flutter. ( Guo, JH; Sun, JL; Zhang, HC; Zhang, N; Zhang, P, 2005)
"To compare the efficacy and safety of ibutilide versus propafenone in immediate cardioversion of atrial fibrillation (AF) and atrial flutter (AFL) lasted less than 90 days."5.11[Immediate cardioversion of atrial fibrillation and atrial flutter lasting less than 90 days by ibutilide versus propafenone: a multicenter study]. ( Fang, Q; Ge, JB; Guo, JH; Guo, JX; Han, SM; Sun, YM; Wan, Z; Zhang, HC; Zheng, YA; Zhu, WQ, 2005)
"We conclude that the association of propafenone with long bursts gives the best result for interruption of new onset atrial flutter by transoesophageal pacing."5.09New onset atrial flutter termination by overdrive transoesophageal pacing: effects of different protocols of stimulation. ( Doni, F; Fiorentini, C; Manfredi, M; Piemonti, C; Rimondini, A; Staffiere, E; Todd, S, 2000)
"The safety and efficacy of amiodarone and propafenone in converting atrial fibrillation or flutter after cardiac surgery were compared in a randomized double-blind trial."5.08Intravenous amiodarone vs propafenone for atrial fibrillation and flutter after cardiac operation. ( Cappiello, E; Di Biasi, P; Mangini, A; Paje, A; Santoli, C; Scrofani, R, 1995)
"Safety and efficacy of propafenone and disopyramide for long-term maintenance of sinus rhythm after electrical cardioversion was studied in 56 patients with chronic atrial fibrillation (median arrhythmia duration, 5 months)."5.08Propafenone versus disopyramide for maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation: a randomized, double-blind study. PRODIS Study Group. ( Crijns, HJ; Gosselink, AT; Lie, KI, 1996)
"The results suggest that propafenone produces a more prompt effect in converting patients from atrial fibrillation or flutter to normal sinus rhythm."5.08The efficacy and safety of intravenous propafenone versus intravenous amiodarone in the conversion of atrial fibrillation or flutter after cardiac surgery. ( Larbuisson, R; Stiels, B; Venneman, I, 1996)
"This multicentre, randomized, double-blind study, conducted in parallel groups, was designed to compare the efficacy and safety of cibenzoline (C) and oral propafenone (P) in the prevention of recurrent atrial arrhythmias (M) over a 6-month period."5.08[Cibenzoline versus propafenone by the oral route for preventing recurrence of atrial arrhythmia: multicenter, randomized, double-blind study]. ( Bleinc, D; Canler, A; Lardoux, H; Maison Blanche, P; Marchand, X; Péraudeau, P; Rouesnel, P; Scheck, F, 1996)
"To assess the cardiac and extracardiac safety and efficacy of flecainide versus propafenone in patients suffering from episodes of paroxysmal atrial fibrillation (AF) or atrial flutter, 97 patients were enrolled in a randomized, open-label, long-term, parallel, comparative multicenter study."5.08Comparison of the safety and efficacy of flecainide versus propafenone in hospital out-patients with symptomatic paroxysmal atrial fibrillation/flutter. The Flecainide AF French Study Group. ( Aliot, E; Denjoy, I, 1996)
"Fifty patients with symptomatic type I atrial flutter in whom termination of the arrhythmia with transesophageal stimulation was unsuccessful were randomized to undergo a repeat procedure after intravenous propafenone (n = 25) or placebo (n = 25)."5.08Efficacy of intravenous propafenone in termination of atrial flutter by overdrive transesophageal pacing previously ineffective. ( Bertaglia, E; D'Este, D; Franceschi, M; Mantovan, R; Pascotto, P; Zanocco, A, 1997)
"Efficacy and safety of intravenous flecainide (2 mg/kg body weight in 10 minutes), verapamil (10 mg in 1 minute), and propafenone (2 mg/kg body weight in 10 minutes) were investigated in 90 consecutive patients with atrial fibrillation (AF) or flutter (AFL)."5.07Acute pharmacologic conversion of atrial fibrillation and flutter: the role of flecainide, propafenone, and verapamil. ( Kingma, JH; Suttorp, MJ, 1992)
"In a single-blind randomized study, the efficacy and safety of intravenous propafenone (2 mg/kg body weight per 10 min) versus flecainide (2 mg/kg per 10 min) were assessed in 50 patients with atrial fibrillation or flutter."5.06The value of class IC antiarrhythmic drugs for acute conversion of paroxysmal atrial fibrillation or flutter to sinus rhythm. ( Jessurun, ER; Kingma, JH; Lie, KI; Lie-A-Huen, L; Suttorp, MJ; van Hemel, NM, 1990)
"The efficacy of intravenous propafenone (2 mg/kg) was assessed in 83 consecutive patients: 68 with atrial fibrillation (AF) and 15 with atrial flutter lasting less than 15 days."5.06Effectiveness of intravenous propafenone for conversion of atrial fibrillation and flutter of recent onset. ( Bianconi, L; Boccadamo, R; Gentili, C; Pappalardo, A; Pistolese, M, 1989)
"This review summarizes the results of placebo-controlled trials of propafenone, a class IC antiarrhythmic drug, in patients with supraventricular tachycardia, atrial fibrillation (AF), and atrial flutter."4.80Placebo-controlled evaluations of propafenone for atrial tachyarrhythmias. ( Rae, AP, 1998)
" These antiarrhythmics, prescribed to prevent atrial fibrillation (3 patients) and atrial flutter (5 patients), were flecainide in 4 cases, propafenone in 2 cases and cibenzoline and hydroquinidine respectively associated with digitoxine and propranolol."4.79[Supraventricular tachycardia with wide QRS complexes during Vaughan-Williams class I anti-arrhythmic treatment. Diagnostic and therapeutic implications]. ( Aouate, P; Benassar, A; Fontaine, G; Frank, R; Jacquemin, M; Laborde, JP; Tageddine, R; Tonet, J; Turlure, A, 1995)
"The use of flecainide and propafenone for medical cardioversion of atrial fibrillation (AF) and atrial flutter/intra-atrial reentrant tachycardia (IART) is well-described in adults without congenital heart disease (CHD)."4.31Medical cardioversion of atrial fibrillation and flutter with class IC antiarrhythmic drugs in young patients with and without congenital heart disease. ( Alexander, ME; Bezzerides, VJ; DeWitt, ES; Dionne, A; Eberly, LM; Mah, DY; O'Leary, ET; Przybylski, R; Triedman, JK; Walsh, EP, 2023)
"Our objective was to evaluate the efficacy and safety of intravenous (IV) sotalol in the treatment of incessant tachyarrhythmias in children with normal cardiac function."3.85Efficacy of Intravenous Sotalol for Treatment of Incessant Tachyarrhythmias in Children. ( Ge, H; Jiang, H; Li, X; Liu, H; Zhang, Y, 2017)
"We present two cases of proarrhythmia after propafenone treatment."3.74[Proarrhythmic effect of propafenone in patients with atrial fibrillation and atrial flutter]. ( Jastrzebski, M, 2008)
" The case history is reported of a patient with atrial flutter and atrial fibrillation who developed Brugada-like ECG changes when treated with propafenone."3.74Propafenone-induced Brugada-like ECG changes mistaken as acute myocardial infarction. ( Chutani, S; Grubb, B; Imran, N; Kanjwal, Y, 2008)
"The antiarrhythmic efficacy of the novel ultrarapid delayed rectifier potassium current (IKur) blocker (2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide (DPO-1) was compared with efficacies of the standard class III rapidly activating component of delayed rectifier potassium current (IKr) blockers [+-N-[1'-(6-cyano-1,2,3,4-tetrahydro-2-napthalenyl)-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-6-yl] methanesulfonamide hydrochloride (MK499) and ibutilide and the class IC agent propafenone in a canine model of Y-shaped intracaval and right atrial free wall surgical lesions producing the substrate for reentrant atrial flutter."3.73In vivo antiarrhythmic and cardiac electrophysiologic effects of a novel diphenylphosphine oxide IKur blocker (2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide. ( Lynch, JJ; Regan, CP; Stump, GL; Wallace, AA, 2005)
"The effectiveness and safety of ibutilide (IB) use in patients receiving amiodarone or propafenone for atrial flutter (AFL) and atrial fibrillation (AF) were compared to IB alone."3.73Efficacy and safety of ibutilide for cardioversion of atrial flutter and fibrillation in patients receiving amiodarone or propafenone. ( Fragakis, N; Katsaris, G; Kozirakis, M; Maligkos, G; Papadopoulos, N; Papanastasiou, S; Tsaritsaniotis, E, 2005)
"A 74-year-old man with a structurally normal heart presented with typical atrial flutter, after treatment of atrial fibrillation with propafenone."3.72Typical counterclockwise atrial flutter occurring despite absence of the inferior vena cava. ( Gilkeson, RC; Varma, N; Waldo, AL, 2004)
"24 consecutive patients with atrial fibrillation (age 54 (12) years; 5 female, 19 male) developing atrial flutter while taking propafenone (n = 12) or flecainide (n = 12)."3.71Class IC antiarrhythmic drug induced atrial flutter: electrocardiographic and electrophysiological findings and their importance for long term outcome after right atrial isthmus ablation. ( Nabar, A; Rodriguez, LM; Timmermans, C; van Mechelen, R; Wellens, HJ, 2001)
"We describe a case of 1:1 atrial flutter in a patient with coronary disease taking propafenone."3.70Atrial flutter with 1:1 atrioventricular conduction caused by propafenone. ( Adams, PC; el-Harari, MB, 1998)
"Among the 136 patients treated for atrial fibrillation with amiodarone (n = 96) or propafenone (n = 40), 15 (11%, mean age 65."3.70Persistent atrial flutter in patients treated for atrial fibrillation with amiodarone and propafenone: electrophysiologic characteristics, radiofrequency catheter ablation, and risk prediction. ( Chang, MS; Chen, SA; Chen, YJ; Chiang, CE; Ding, YA; Feng, AN; Lee, SH; Tai, CT; Yu, WC, 1999)
"Ibutilide, with a unique increase in atrial refractoriness, was more effective in conversion of atrial flutter than were propafenone and amiodarone."3.70Electropharmacologic effects of class I and class III antiarrhythmia drugs on typical atrial flutter: insights into the mechanism of termination. ( Chang, MS; Chen, SA; Chen, YJ; Feng, AN; Tai, CT; Yu, WC, 1998)
"We assessed the safety and efficacy of intravenous propafenone in the treatment of atrial fibrillation and flutter of recent onset (1-10 days)."3.69[Efficacy of intravenous propafenone in the management of arterial flutter and fibrillation of recent onset]. ( Minutiello, L, 1994)
"The effects of procainamide and propafenone on the composition of the excitable gap (EG) were studied in a canine model of atrial flutter (AFI) around the tricuspid valve."3.69Effects of procainamide and propafenone on the composition of the excitable gap in canine atrial reentry tachycardia. ( Derakhchan, K; Kus, T; Lambert, C; Pagé, P, 1994)
" In order to prevent/terminate fibrillation propafenone (Rytmonorm, 450-600 mg/day) was started, however this therapy resulted in permanent atrial flutter of 230-270/min mainly with 2:1 antrioventricular conduction."3.69[Persistent atrial flutter induced by propafenone (Rytmonorm)]. ( Fazekas, T; Kiss, J; Pap, I; Rudas, L, 1994)
"0 micrograms/kg, n = 8), a class III drug, on atrial flutter (AF) caused by reentry were compared with those of disopyramide (1."3.68Effects of pentisomide and E-4031 on canine atrial flutter due to reentry: a comparative study with disopyramide and propafenone. ( Inoue, H; Nozaki, A; Saihara, S; Sugimoto, T; Usui, M; Yamashita, T, 1991)
" To determine the exact role played by these two electrophysiologic effects in the termination of reentry, the effects of disopyramide, flecainide, propafenone and E-4031, a new class III drug, were examined in a canine model of atrial flutter (cycle length 120 +/- 4 to 131 +/- 3 ms) caused by reentry."3.68Effects of antiarrhythmic drugs on canine atrial flutter due to reentry: role of prolongation of refractory period and depression of conduction to excitable gap. ( Inoue, H; Nozaki, A; Sugimoto, T; Yamashita, T, 1991)
"We describe a case of dangerous acceleration of conduction through an accessory pathway produced by the Class IC agent propafenone during routine electrophysiological study of a patient with Wolff-Parkinson-White syndrome."3.68Acceleration of conduction within an accessory pathway with propafenone. ( Holt, P; Sowton, GE; Sulke, AN, 1990)
"One hundred nine patients with recurrent episodes of symptomatic atrial fibrillation or flutter, or both, who had failed one to five previous antiarrhythmic drug trials were treated with propafenone and, subsequently, sotalol if atrial fibrillation recurred."3.68Therapy of refractory symptomatic atrial fibrillation and atrial flutter: a staged care approach with new antiarrhythmic drugs. ( Antman, EM; Beamer, AD; Cantillon, C; Friedman, PL; McGowan, N, 1990)
"Sixty patients who had recurrent episodes of symptomatic atrial fibrillation or flutter, or both, and who had failed one to five prior drug trials were treated with open label oral propafenone hydrochloride."3.67Long-term oral propafenone therapy for suppression of refractory symptomatic atrial fibrillation and atrial flutter. ( Antman, EM; Beamer, AD; Cantillon, C; Friedman, PL; Goldman, L; McGowan, N, 1988)
"The safety and efficacy of intravenous Propafenone, in the treatment of atrial fibrillation (a."3.67[Fibrillation and atrial flutter. Immediate control and conversion to sinus rhythm with intravenous propafenone]. ( Bianconi, L; Boccadamo, R; Broglia, R; Pappalardo, A; Pistolese, M, 1987)
"Forty-seven patients with chronic atrial fibrillation and (or) flutter in whom the clinical picture and the length of arrhythmia indicated that drug-mediated cardioversion should be tried were treated with a combination of lidoflazine and propafenon."3.66[Combined use of propafenon and lidoflazine in chronic atrial fibrillation and flutter (author's transl)]. ( Beck, OA; Hochrein, H, 1980)
"We randomly assigned 294 patients with paroxysmal atrial fibrillation and no history of antiarrhythmic drug use to an initial treatment strategy of either radiofrequency catheter ablation (146 patients) or therapy with class IC or class III antiarrhythmic agents (148 patients)."2.77Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation. ( Cosedis Nielsen, J; Englund, A; Hansen, PS; Hartikainen, J; Hindricks, G; Johannessen, A; Kongstad, O; Mortensen, LS; Pehrson, S; Raatikainen, P; Walfridsson, H, 2012)
" Despite careful precautions, serious proarrhythmias, the major limiting side effect of dofetilide, still occurred during long-term follow-up."2.73Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function. ( Bauman, JL; Kehoe, RF; Leal, S; Mykytsey, A; Razminia, M; Saleem, M; Wang, T; Zheutlin, T, 2007)
"Propafenone is an effective drug for preventing supraventricular tachyarrhythmia, but the incidence of side effects during longterm therapy in patients with such arrhythmias has not been adequately reported."2.68Safety and tolerability of long-term propafenone therapy for supraventricular tachyarrhythmias. The Propafenone Multicenter Study Group. ( Anderson, JL; Podrid, PJ, 1996)
"Propafenone, 2 mg/kg was given over 15 min and blood pressure and heart rate were monitored in the following hour."2.66[Efficacy of propafenone in supraventricular arrhythmias]. ( Ayala, A; Goich, J; Kauffmann, R; Manzur, F; Parra, C, 1989)
" With the intravenous administration of the drug in a dosage of 1."2.65[Propafenon therapy of arrhythmias in infancy and childhood (author's transl)]. ( Eigster, G; Weber, H; Wesselhoeft, H, 1981)
"Atrial flutter is most often arising from a macroreentry circuit in the right atrium or around scar tissue in case or previous cardiothoracic surgery."2.43[Atrial flutter and fibrillation]. ( Scharf, C, 2005)
"Electrocardiography (ECG) showed ventricular tachycardia."1.35A case of myotonic dystrophy presenting with ventricular tachycardia and atrial fibrillation. ( Eroğlu, S; Müderrisoğlu, H; Ozbiçer, S; Ozin, B, 2009)
"Oral propafenone was administered and within 6 hours no further arrhythmias or side effects were noted."1.30Atrial flutter in a pediatric patient in the immediate period after the Fontan procedure: control with oral propafenone. ( Herzberg, GZ; Rossi, AF, 1997)
" In this study, we prospectively investigated the effects of AFI ablation and continuation of drug therapy in patients with AF who developed AFI due to long-term administration of class IC antiarrhythmic drugs."1.30Radiofrequency ablation of atrial flutter due to administration of class IC antiarrhythmic drugs for atrial fibrillation. ( Jung, W; Lewalter, T; Lüderitz, B; Schumacher, B; Vahlhaus, C; Wolpert, C, 1999)
" Dosage and serum levels of propafenone did not differ whether the patients were treated successfully or not."1.29Clinical experience with propafenone for cardiac arrhythmias in the young. ( Bourgeous, M; Heusch, A; Kramer, HH; Krogmann, ON; Rammos, S, 1994)
"Propafenone terminated tachyarrhythmias in all patients during or within a few minutes after stopping infusion (mean conversion time: 6."1.28[Use of propafenone in emergency therapy]. ( Di Ieso, N; Guardascione, A; Liguori, A; Pellegrino, G; Piatto, A; Ruggiero, P; Scarnera, P, 1989)
"Propafenone was less effective (mean effect 3."1.27European experience with the antiarrhythmic efficacy of propafenone for supraventricular and ventricular arrhythmias. ( Assayag, P; Coumel, P; Leclercq, JF, 1984)

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-199010 (12.99)18.7374
1990's37 (48.05)18.2507
2000's21 (27.27)29.6817
2010's7 (9.09)24.3611
2020's2 (2.60)2.80

Authors

AuthorsStudies
Gagloeva, DA1
Dzaurova, KM1
Zelberg, MA1
Mironov, NY1
Yuricheva, YA1
Sokolov, SF1
Golitsyn, SP1
Przybylski, R1
Eberly, LM1
Alexander, ME1
Bezzerides, VJ1
DeWitt, ES1
Dionne, A1
Mah, DY1
Triedman, JK1
Walsh, EP1
O'Leary, ET1
Bergonti, M1
Assanelli, E1
Agostoni, P1
Yu, Z1
Xiang, M1
Ma, C1
Zhang, S1
Yang, Y2
Konak, M1
Alp, H1
Tarakçı, N1
Baysal, T1
Ors, R1
Li, X1
Zhang, Y2
Liu, H1
Jiang, H1
Ge, H1
Jastrzebski, M1
Eroğlu, S1
Ozin, B1
Ozbiçer, S1
Müderrisoğlu, H1
Tsai, CF1
Sia, SK1
Lin, MC1
Wu, DJ1
Ueng, KC1
Blecher, GE1
Stiell, IG1
Rowe, BH1
Lang, E1
Brison, RJ1
Perry, JJ1
Clement, CM1
Borgundvaag, B1
Langhan, T1
Magee, K1
Stenstrom, R1
Birnie, D1
Wells, GA1
Cosedis Nielsen, J1
Johannessen, A1
Raatikainen, P1
Hindricks, G1
Walfridsson, H1
Kongstad, O1
Pehrson, S1
Englund, A1
Hartikainen, J1
Mortensen, LS1
Hansen, PS1
Jalil, E2
Mensour, B2
Vinet, A2
Kus, T3
Chiladakis, JA1
Kalogeropoulos, A1
Patsouras, N1
Manolis, AS1
Hongo, RH1
Themistoclakis, S2
Raviele, A2
Bonso, A2
Rossillo, A1
Glatter, KA1
Scheinman, MM1
Bertaglia, E2
Zoppo, F1
Proclemer, A1
Verlato, R1
Corò, L1
Mantovan, R2
Pascotto, P2
Varma, N1
Gilkeson, RC1
Waldo, AL1
Sun, JL1
Guo, JH2
Zhang, N1
Zhang, HC2
Zhang, P1
Fang, Q1
Zheng, YA1
Sun, YM1
Zhu, WQ1
Wan, Z1
Guo, JX1
Ge, JB1
Han, SM1
Wiesfeld, AC1
Ansink, JM1
van Veldhuisen, DJ1
van Gelder, IC1
Stump, GL1
Wallace, AA1
Regan, CP1
Lynch, JJ1
Fragakis, N1
Papadopoulos, N1
Papanastasiou, S1
Kozirakis, M1
Maligkos, G1
Tsaritsaniotis, E1
Katsaris, G1
Scharf, C1
Kehl, HG1
Debus, V1
Stege, D1
Tjan, TD1
Vogt, J1
Schulze-Bahr, E1
Mykytsey, A1
Bauman, JL1
Razminia, M1
Zheutlin, T1
Wang, T1
Saleem, M1
Leal, S1
Kehoe, RF1
Chutani, S1
Imran, N1
Grubb, B1
Kanjwal, Y1
Gmeiner, R1
Sterz, H1
Beck, OA1
Hochrein, H1
Weber, H1
Eigster, G1
Wesselhoeft, H1
Coumel, P1
Leclercq, JF1
Assayag, P1
Doni, F4
Della Bella, P1
Kheir, A2
Manfredi, M4
Piemonti, C4
Staffiere, E4
Rimondini, A4
Fiorentini, C3
Heusch, A1
Kramer, HH1
Krogmann, ON1
Rammos, S1
Bourgeous, M1
Minutiello, L1
Derakhchan, K1
Pagé, P1
Lambert, C1
Fazekas, T1
Kiss, J1
Pap, I1
Rudas, L1
Gutiérrez-Larraya, F1
Jabón, A1
Manz, M1
Lüderitz, B2
Di Biasi, P1
Scrofani, R1
Paje, A1
Cappiello, E1
Mangini, A1
Santoli, C1
Hancock, EW1
Aliot, E1
Denjoy, I1
Todd, S3
Aouate, P1
Frank, R1
Fontaine, G1
Tonet, J1
Tageddine, R1
Benassar, A1
Turlure, A1
Jacquemin, M1
Laborde, JP1
Podrid, PJ1
Anderson, JL1
Crijns, HJ1
Gosselink, AT1
Lie, KI2
Larbuisson, R1
Venneman, I1
Stiels, B1
Lardoux, H1
Maison Blanche, P1
Marchand, X1
Canler, A1
Rouesnel, P1
Bleinc, D1
Péraudeau, P1
Scheck, F1
D'Este, D1
Zanocco, A1
Franceschi, M1
Brembilla-Perrot, B1
Terrier de la Chaise, A1
Jacquemin, L1
Beurrier, D1
Houplon, P1
Louis, P1
Danchin, N1
Herzberg, GZ1
Rossi, AF1
Huang, DT1
Monahan, KM1
Zimetbaum, P1
Papageorgiou, P1
Epstein, LM1
Josephson, ME1
Tai, CT2
Chen, SA2
Feng, AN2
Yu, WC2
Chen, YJ2
Chang, MS2
el-Harari, MB1
Adams, PC1
Rae, AP1
Schumacher, B1
Jung, W1
Lewalter, T1
Vahlhaus, C1
Wolpert, C1
Nabar, A2
Rodriguez, LM2
Timmermans, C2
Smeets, JL1
Wellens, HJ2
Carrel, T1
Meyer, B1
Candinas, R1
Turina, M1
Schmid, ER1
Chiang, CE1
Lee, SH1
Ding, YA1
Naccarelli, GV1
Dell'Orfano, JT1
Wolbrette, DL1
Patel, HM1
Luck, JC1
Wirth, KJ1
Knobloch, K1
van Mechelen, R1
Gillor, A1
Korsch, E1
Kingma, JH2
Suttorp, MJ2
Inoue, H2
Yamashita, T2
Usui, M1
Nozaki, A2
Saihara, S1
Sugimoto, T2
Guccione, P1
Drago, F1
Di Donato, RM1
Cicini, MP1
Pasquini, L1
Marino, B1
Marcelletti, C1
Ragonese, P1
Jessurun, ER1
Lie-A-Huen, L1
van Hemel, NM1
Antman, EM2
Beamer, AD2
Cantillon, C2
McGowan, N2
Friedman, PL2
Sulke, AN1
Holt, P1
Sowton, GE1
Murdock, CJ1
Kyles, AE1
Yeung-Lai-Wah, JA1
Qi, A1
Vorderbrugge, S1
Kerr, CR1
Kauffmann, R1
Goich, J1
Parra, C1
Ayala, A1
Manzur, F1
Liguori, A1
Pellegrino, G1
Di Ieso, N1
Piatto, A1
Ruggiero, P1
Scarnera, P1
Guardascione, A1
Bianconi, L2
Boccadamo, R2
Pappalardo, A2
Gentili, C1
Pistolese, M2
Marchlinski, FE1
Goldman, L1
Broglia, R1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Medical Antiarrhythmic Treatment or Radiofrequency Ablation in Paroxysmal Atrial Fibrillation: A Randomized Prospective Multicentre Study (MANTRA-PAF)[NCT00133211]Phase 3294 participants (Actual)Interventional2005-09-30Completed
Inhibition of Atrial Fibrillation by Elimination of Transitional Mechanisms[NCT02758002]0 participants (Actual)Interventional2016-01-28Withdrawn
Radiofrequency vs Cryoballoon Catheter Ablation for Pulmonary Vein Isolation in Patients With Atrial Fibrillation - Effect on Atrial Fibrillation Burden Assessed by Implantable Cardiac Monitor (RACE-AF Trial)[NCT03805555]105 participants (Actual)Interventional2015-06-30Completed
First-line Cryoablation for Early Treatment of Persistent Atrial Fibrillation - a Randomized Study Comparing Early Trigger Isolation Using the Cryoballoon Versus Antiarrhythmic Medication[NCT05939076]Phase 3220 participants (Anticipated)Interventional2023-08-21Not yet recruiting
Hybrid Ablation Plus Medical Therapy for Persistent Atrial Fibrillation (HYBRID AF)[NCT04190186]90 participants (Anticipated)Interventional2020-06-25Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for propafenone and Atrial Flutter

ArticleYear
[Atrial flutter and fibrillation].
    Praxis, 2005, Nov-09, Volume: 94, Issue:45

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia

2005
[Tachycardias: considerations in childhood in the 90s].
    Anales espanoles de pediatria, 1993, Volume: 39, Issue:6

    Topics: Adenosine; Adolescent; Adult; Amiodarone; Atrial Flutter; Child; Child, Preschool; Electrocardiograp

1993
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy.
    European heart journal, 1993, Volume: 14 Suppl E

    Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Fle

1993
[Supraventricular tachycardia with wide QRS complexes during Vaughan-Williams class I anti-arrhythmic treatment. Diagnostic and therapeutic implications].
    Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Drug Th

1995
Placebo-controlled evaluations of propafenone for atrial tachyarrhythmias.
    The American journal of cardiology, 1998, Oct-16, Volume: 82, Issue:8A

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Controlled Clinic

1998
Cost-effective management of acute atrial fibrillation: role of rate control, spontaneous conversion, medical and direct current cardioversion, transesophageal echocardiography, and antiembolic therapy.
    The American journal of cardiology, 2000, May-25, Volume: 85, Issue:10A

    Topics: Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cost-Benefit An

2000

Trials

23 trials available for propafenone and Atrial Flutter

ArticleYear
[Efficacy and safety of ibutilide for conversion of atrial fibrillation/flutter].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2013, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Aged; Atrial Fibrillation; Atrial Flutter; Female; Humans; Male; Middle Aged; Pro

2013
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Radiofrequency ablation as initial therapy in paroxysmal atrial fibrillation.
    The New England journal of medicine, 2012, Oct-25, Volume: 367, Issue:17

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Cost of Illnes

2012
Ibutilide added to propafenone for the conversion of atrial fibrillation and atrial flutter.
    Journal of the American College of Cardiology, 2004, Aug-18, Volume: 44, Issue:4

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Drug Administrati

2004
Use of ibutilide in cardioversion of patients with atrial fibrillation or atrial flutter treated with class IC agents.
    Journal of the American College of Cardiology, 2004, Aug-18, Volume: 44, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Drug Administration Schedule; Dru

2004
Clinical comparison of ibutilide and propafenone for converting atrial flutter.
    Cardiovascular drugs and therapy, 2005, Volume: 19, Issue:1

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Flutter; Dose-Response Relationship, Drug; Double-Blind

2005
[Immediate cardioversion of atrial fibrillation and atrial flutter lasting less than 90 days by ibutilide versus propafenone: a multicenter study].
    Zhonghua yi xue za zhi, 2005, Mar-30, Volume: 85, Issue:12

    Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Electrocardiog

2005
Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function.
    Journal of cardiovascular pharmacology and therapeutics, 2007, Volume: 12, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flut

2007
[Propafenon therapy of arrhythmias in infancy and childhood (author's transl)].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1981, Volume: 129, Issue:7

    Topics: Adolescent; Age Factors; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Flutter; Atrioventricu

1981
Atrial flutter termination by overdrive transesophageal pacing and the facilitating effect of oral propafenone.
    The American journal of cardiology, 1995, Dec-15, Volume: 76, Issue:17

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac Pacing, Artificial; Electrocar

1995
Intravenous amiodarone vs propafenone for atrial fibrillation and flutter after cardiac operation.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1995, Volume: 9, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Coronary Disease; Dos

1995
Comparison of the safety and efficacy of flecainide versus propafenone in hospital out-patients with symptomatic paroxysmal atrial fibrillation/flutter. The Flecainide AF French Study Group.
    The American journal of cardiology, 1996, Jan-25, Volume: 77, Issue:3

    Topics: Adult; Aged; Ambulatory Care; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Female; F

1996
[Facilitating effect of propafenone pretreatment in the interruption of atrial flutter by transesophageal pacing].
    Cardiologia (Rome, Italy), 1996, Volume: 41, Issue:2

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac Pacing, Artificial; Esophagus; Female;

1996
Safety and tolerability of long-term propafenone therapy for supraventricular tachyarrhythmias. The Propafenone Multicenter Study Group.
    The American journal of cardiology, 1996, Aug-15, Volume: 78, Issue:4

    Topics: Administration, Oral; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial

1996
Propafenone versus disopyramide for maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation: a randomized, double-blind study. PRODIS Study Group.
    Cardiovascular drugs and therapy, 1996, Volume: 10, Issue:2

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Chronic Disease; Disopyramide; Do

1996
The efficacy and safety of intravenous propafenone versus intravenous amiodarone in the conversion of atrial fibrillation or flutter after cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 1996, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Fe

1996
Type II atrial flutter interruption with transesophageal pacing: use of propafenone and possible change of the substrate.
    Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:11 Pt 2

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atri

1996
[Cibenzoline versus propafenone by the oral route for preventing recurrence of atrial arrhythmia: multicenter, randomized, double-blind study].
    Annales de cardiologie et d'angeiologie, 1996, Volume: 45, Issue:8

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation

1996
Efficacy of intravenous propafenone in termination of atrial flutter by overdrive transesophageal pacing previously ineffective.
    The American journal of cardiology, 1997, Feb-15, Volume: 79, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Flutter; Electric Countershock; Heart Rate; Humans; Middle Aged

1997
New onset atrial flutter termination by overdrive transoesophageal pacing: effects of different protocols of stimulation.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2000, Volume: 2, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac Pacing, Artificia

2000
Acute pharmacologic conversion of atrial fibrillation and flutter: the role of flecainide, propafenone, and verapamil.
    The American journal of cardiology, 1992, Aug-20, Volume: 70, Issue:5

    Topics: Atrial Fibrillation; Atrial Flutter; Drug Evaluation; Female; Flecainide; Humans; Male; Middle Aged;

1992
The value of class IC antiarrhythmic drugs for acute conversion of paroxysmal atrial fibrillation or flutter to sinus rhythm.
    Journal of the American College of Cardiology, 1990, Volume: 16, Issue:7

    Topics: Atrial Fibrillation; Atrial Flutter; Electrocardiography; Female; Flecainide; Humans; Male; Middle A

1990
[Efficacy of propafenone in supraventricular arrhythmias].
    Revista medica de Chile, 1989, Volume: 117, Issue:4

    Topics: Adult; Aged; Atrial Fibrillation; Atrial Flutter; Blood Pressure; Electrocardiography; Female; Heart

1989
Effectiveness of intravenous propafenone for conversion of atrial fibrillation and flutter of recent onset.
    The American journal of cardiology, 1989, Aug-01, Volume: 64, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Atrial Flutter; Clinical Trials as Topic; Elect

1989

Other Studies

48 other studies available for propafenone and Atrial Flutter

ArticleYear
Early initiation of anti-relapse antiarrhythmic therapy in patients with atrial fibrillation and flutter after pharmacological cardioversion with refralon.
    Kardiologiia, 2023, Jun-30, Volume: 63, Issue:6

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Electric Countershock; Humans; Long QT

2023
Medical cardioversion of atrial fibrillation and flutter with class IC antiarrhythmic drugs in young patients with and without congenital heart disease.
    Journal of cardiovascular electrophysiology, 2023, Volume: 34, Issue:12

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Electric Countershoc

2023
The Wrong Drug That Led to the Right Diagnosis.
    Circulation, 2019, 11-05, Volume: 140, Issue:19

    Topics: Action Potentials; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; D

2019
Successful treatment of atrial flutter with propafenone and synchronized cardioversion in a newborn.
    Indian journal of pediatrics, 2014, Volume: 81, Issue:4

    Topics: Atrial Flutter; Electric Countershock; Humans; Infant, Newborn; Propafenone

2014
Efficacy of Intravenous Sotalol for Treatment of Incessant Tachyarrhythmias in Children.
    The American journal of cardiology, 2017, 05-01, Volume: 119, Issue:9

    Topics: Adolescent; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Child; Child, Preschool; Dr

2017
[Proarrhythmic effect of propafenone in patients with atrial fibrillation and atrial flutter].
    Kardiologia polska, 2008, Volume: 66, Issue:11

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bundle-Branch Blo

2008
A case of myotonic dystrophy presenting with ventricular tachycardia and atrial fibrillation.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2009, Volume: 37, Issue:5

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Defibrillators, Implantable

2009
Unstable wide complex tachycardia during propafenone therapy.
    Resuscitation, 2010, Volume: 81, Issue:8

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Electrocardiography; Female; Hear

2010
Use of rate control medication before cardioversion of recent-onset atrial fibrillation or flutter in the emergency department is associated with reduced success rates.
    CJEM, 2012, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation;

2012
Excitable gap composition in the presence of antiarrhythmic drugs in common human atrial flutter.
    The Canadian journal of cardiology, 2003, Mar-15, Volume: 19, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Female; Heart Co

2003
Different clinical courses and predictors of atrial fibrillation occurrence after transisthmic ablation in patients with preablation lone atrial flutter, coexistent atrial fibrillation, and drug induced atrial flutter.
    Pacing and clinical electrophysiology : PACE, 2004, Volume: 27, Issue:11

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Co

2004
Typical counterclockwise atrial flutter occurring despite absence of the inferior vena cava.
    Heart rhythm, 2004, Volume: 1, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Electrophysiol

2004
Broad complex tachycardia during treatment of atrial fibrillation with a 1c antiarrhythmic drug: ventricular or supraventricular proarrhythmia?
    International journal of cardiology, 2006, Feb-08, Volume: 107, Issue:1

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Drug Thera

2006
In vivo antiarrhythmic and cardiac electrophysiologic effects of a novel diphenylphosphine oxide IKur blocker (2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Flutter; Atrial Function; Dogs; Electrocardiography; Electro

2005
Efficacy and safety of ibutilide for cardioversion of atrial flutter and fibrillation in patients receiving amiodarone or propafenone.
    Pacing and clinical electrophysiology : PACE, 2005, Volume: 28, Issue:9

    Topics: Adult; Aged; Amiodarone; Analysis of Variance; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial F

2005
[Atrial flutter after orthotopic heart transplantation due to recipient-to-donor transatrial conduction].
    Herzschrittmachertherapie & Elektrophysiologie, 2005, Volume: 16, Issue:4

    Topics: Adolescent; Anti-Arrhythmia Agents; Atrial Flutter; Combined Modality Therapy; Electric Countershock

2005
Propafenone-induced Brugada-like ECG changes mistaken as acute myocardial infarction.
    Emergency medicine journal : EMJ, 2008, Volume: 25, Issue:2

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Brugada Syndrome; Catheter Ablati

2008
[Conservative therapy of supraventricular tachycardias].
    Wiener medizinische Wochenschrift (1946), 1984, Oct-31, Volume: 134, Issue:19-20

    Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter;

1984
[Combined use of propafenon and lidoflazine in chronic atrial fibrillation and flutter (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Sep-05, Volume: 105, Issue:36

    Topics: Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Chronic Disease; Drug Therapy, Co

1980
European experience with the antiarrhythmic efficacy of propafenone for supraventricular and ventricular arrhythmias.
    The American journal of cardiology, 1984, Nov-14, Volume: 54, Issue:9

    Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillati

1984
Clinical experience with propafenone for cardiac arrhythmias in the young.
    European heart journal, 1994, Volume: 15, Issue:8

    Topics: Administration, Oral; Adolescent; Arrhythmias, Cardiac; Atrial Flutter; Cardiac Complexes, Premature

1994
[Efficacy of intravenous propafenone in the management of arterial flutter and fibrillation of recent onset].
    Minerva cardioangiologica, 1994, Volume: 42, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Atrial Flutter; Echocardiography; Female; Human

1994
Effects of procainamide and propafenone on the composition of the excitable gap in canine atrial reentry tachycardia.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Action Potentials; Anesthesia; Animals; Atrial Flutter; Atrial Function; Chloralose; Diastole; Disea

1994
[Persistent atrial flutter induced by propafenone (Rytmonorm)].
    Orvosi hetilap, 1994, Aug-14, Volume: 135, Issue:33

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Female; Humans; Propafenone

1994
Atrial flutter in a man with mediastinal cancer.
    Hospital practice (1995), 1996, Jan-15, Volume: 31, Issue:1

    Topics: Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Humans; Male; Mediastinal Neoplasms; Mi

1996
[Can 1/1 atrial flutter be foreseen by class I anti-arrhythmics?].
    Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:7

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Flutter; Disopyramide; Electrocardiography; Female; Flecainide;

1997
Atrial flutter in a pediatric patient in the immediate period after the Fontan procedure: control with oral propafenone.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:12 Pt 1

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Flutter; Child, Preschool; Electrocardiography;

1997
Hybrid pharmacologic and ablative therapy: a novel and effective approach for the management of atrial fibrillation.
    Journal of cardiovascular electrophysiology, 1998, Volume: 9, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flut

1998
Electropharmacologic effects of class I and class III antiarrhythmia drugs on typical atrial flutter: insights into the mechanism of termination.
    Circulation, 1998, May-19, Volume: 97, Issue:19

    Topics: Adult; Aged; Amiodarone; Analysis of Variance; Anti-Arrhythmia Agents; Atrial Flutter; Atrial Functi

1998
Atrial flutter with 1:1 atrioventricular conduction caused by propafenone.
    Pacing and clinical electrophysiology : PACE, 1998, Volume: 21, Issue:10

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atrioventricular Node; Coronary Artery

1998
Radiofrequency ablation of atrial flutter due to administration of class IC antiarrhythmic drugs for atrial fibrillation.
    The American journal of cardiology, 1999, Mar-01, Volume: 83, Issue:5

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation

1999
Radiofrequency ablation of "class IC atrial flutter" in patients with resistant atrial fibrillation.
    The American journal of cardiology, 1999, Mar-01, Volume: 83, Issue:5

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cath

1999
Intravenous amiodarone versus propafenone for atrial fibrillation and flutter after cardiac surgery: a note of caution.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1996, Volume: 10, Issue:12

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures

1996
Persistent atrial flutter in patients treated for atrial fibrillation with amiodarone and propafenone: electrophysiologic characteristics, radiofrequency catheter ablation, and risk prediction.
    Journal of cardiovascular electrophysiology, 1999, Volume: 10, Issue:9

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; El

1999
Influence of propafenone on resetting and termination of canine atrial flutter.
    Pacing and clinical electrophysiology : PACE, 2000, Volume: 23, Issue:8

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Flutter; Blood Pressure; Cardiac Pacing,

2000
Differential effects of dofetilide, amiodarone, and class lc drugs on left and right atrial refractoriness and left atrial vulnerability in pigs.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:2

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atrial Function, L

2001
Class IC antiarrhythmic drug induced atrial flutter: electrocardiographic and electrophysiological findings and their importance for long term outcome after right atrial isthmus ablation.
    Heart (British Cardiac Society), 2001, Volume: 85, Issue:4

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Electro

2001
[Familial manifestation of idiopathic atrial flutter].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1992, Volume: 140, Issue:1

    Topics: Adolescent; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Child; Digoxin; Drug

1992
Effects of pentisomide and E-4031 on canine atrial flutter due to reentry: a comparative study with disopyramide and propafenone.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Flutter; Disopyramide; Dogs; Electrocardiography; Electrophy

1991
Effects of antiarrhythmic drugs on canine atrial flutter due to reentry: role of prolongation of refractory period and depression of conduction to excitable gap.
    Journal of the American College of Cardiology, 1991, Volume: 18, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac Pacing, Artificial; Disopyramide; Dogs; Ele

1991
Oral propafenone therapy for children with arrhythmias: efficacy and adverse effects in midterm follow-up.
    American heart journal, 1991, Volume: 122, Issue:4 Pt 1

    Topics: Administration, Oral; Adolescent; Arrhythmias, Cardiac; Atrial Flutter; Chi-Square Distribution; Chi

1991
Therapy of refractory symptomatic atrial fibrillation and atrial flutter: a staged care approach with new antiarrhythmic drugs.
    Journal of the American College of Cardiology, 1990, Mar-01, Volume: 15, Issue:3

    Topics: Adult; Aged; Atrial Fibrillation; Atrial Flutter; Data Interpretation, Statistical; Drug Administrat

1990
Acceleration of conduction within an accessory pathway with propafenone.
    International journal of cardiology, 1990, Volume: 28, Issue:1

    Topics: Adult; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Electrocardiography; Electro

1990
Atrial flutter in patients treated for atrial fibrillation with propafenone.
    The American journal of cardiology, 1990, Sep-15, Volume: 66, Issue:7

    Topics: Atrial Fibrillation; Atrial Flutter; Electrocardiography; Follow-Up Studies; Heart Rate; Humans; Pro

1990
[Use of propafenone in emergency therapy].
    La Clinica terapeutica, 1989, Dec-15, Volume: 131, Issue:5

    Topics: Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Drug Evaluation; Electrocardiograp

1989
Propafenone: new therapy for a tough, old arrhythmia.
    Journal of the American College of Cardiology, 1988, Volume: 12, Issue:4

    Topics: Atrial Fibrillation; Atrial Flutter; Electric Countershock; Humans; Propafenone; Recurrence

1988
Long-term oral propafenone therapy for suppression of refractory symptomatic atrial fibrillation and atrial flutter.
    Journal of the American College of Cardiology, 1988, Volume: 12, Issue:4

    Topics: Actuarial Analysis; Administration, Oral; Atrial Fibrillation; Atrial Flutter; Female; Humans; Male;

1988
[Fibrillation and atrial flutter. Immediate control and conversion to sinus rhythm with intravenous propafenone].
    Giornale italiano di cardiologia, 1987, Volume: 17, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Atrial Flutter; Female; Humans; Hypotension; In

1987