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propafenone and Anesthesia

propafenone has been researched along with Anesthesia in 5 studies

Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"The effects of procainamide and propafenone on the composition of the excitable gap (EG) were studied in a canine model of atrial flutter (AFI) around the tricuspid valve."7.69Effects of procainamide and propafenone on the composition of the excitable gap in canine atrial reentry tachycardia. ( Derakhchan, K; Kus, T; Lambert, C; Pagé, P, 1994)
"The effects of procainamide and propafenone on the composition of the excitable gap (EG) were studied in a canine model of atrial flutter (AFI) around the tricuspid valve."3.69Effects of procainamide and propafenone on the composition of the excitable gap in canine atrial reentry tachycardia. ( Derakhchan, K; Kus, T; Lambert, C; Pagé, P, 1994)
"Six dogs were anaesthetized with 1% of halothane-Group I, and six dogs with an equianaesthetic dosage of isoflurane (1."1.29[Hemodynamic effects of propafenone in dogs anesthesized with halothane or isoflurane]. ( Castro, G; Figueiredo, F; Fonseca, P; Freitas, M; Godinho, AM; Morais, J; Providência, LA; Viana, Jda S, 1994)
" During dosing (10 mg kg-1 twice a day for 10 days) no effects on the electrocardiogram, monitored in conscious animals, were observed despite modest reductions (15-18%) in the maximum rate of depolarization of papillary muscle excised 1 or 6 h after completion of the dosing regime."1.28Antiarrhythmic, electrophysiological and haemodynamic effects of prolonged oral dosing with Org 7797 in the anaesthetized rat. ( Delbressine, L; Harris, N; Kane, KA; Muir, AW; Winslow, E, 1992)
"Isoproterenol (ISO) was administered as bolus injections before (0."1.28Beta-adrenoceptor blocking activity of diprafenone in anesthetized dogs: comparison with propafenone and propranolol. ( Cantor, E; Greenberg, S; Paul, J, 1989)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karagueuzian, HS1
Katoh, T1
McCullen, A1
Mandel, WJ1
Peter, T1
Viana, Jda S1
Morais, J1
Castro, G1
Figueiredo, F1
Godinho, AM1
Fonseca, P1
Freitas, M1
Providência, LA1
Derakhchan, K1
Pagé, P1
Lambert, C1
Kus, T1
Delbressine, L1
Harris, N1
Kane, KA1
Muir, AW1
Winslow, E1
Greenberg, S1
Cantor, E1
Paul, J1

Other Studies

5 other studies available for propafenone and Anesthesia

ArticleYear
Electrophysiologic and hemodynamic effects of propafenone, a new antiarrhythmic agent, on the anesthetized, closed-chest dog: comparative study with lidocaine.
    American heart journal, 1984, Volume: 107, Issue:3

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Pacing, Artificial; Dogs; Elect

1984
[Hemodynamic effects of propafenone in dogs anesthesized with halothane or isoflurane].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1994, Volume: 13, Issue:9

    Topics: Anesthesia; Animals; Dogs; Halothane; Hemodynamics; Isoflurane; Propafenone; Random Allocation

1994
Effects of procainamide and propafenone on the composition of the excitable gap in canine atrial reentry tachycardia.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Action Potentials; Anesthesia; Animals; Atrial Flutter; Atrial Function; Chloralose; Diastole; Disea

1994
Antiarrhythmic, electrophysiological and haemodynamic effects of prolonged oral dosing with Org 7797 in the anaesthetized rat.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:12

    Topics: Action Potentials; Administration, Oral; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, C

1992
Beta-adrenoceptor blocking activity of diprafenone in anesthetized dogs: comparison with propafenone and propranolol.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Anti-Arrhythmia Agents; Dihydroalprenolol; Dogs; F

1989