Page last updated: 2024-11-03

promethazine and Psychoses

promethazine has been researched along with Psychoses in 30 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Research Excerpts

ExcerptRelevanceReference
"To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression."8.93Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016)
"To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression."8.85Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009)
"To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression."8.82Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005)
"All medications produced a calming effect within one hour of administration, but only olanzapine and haloperidol reduced agitation by less than 10 points, and only olanzapine reduced aggression by less than four points in the first hour."5.15Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone. ( Baldaçara, L; Cordeiro, DC; Jackoswski, AP; Sanches, M, 2011)
"To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression."4.93Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016)
"Haloperidol in combination with promethazine, and olanzapine, are effective in psychotic agitation, although haloperidol plus promethazine has a more rapid onset of effect faster; lorazepam is effective in non-psychotic agitation, aggression or excitement as well as in acute agitation of unknown origin."4.87[Rapid tranquillisation; review of the literature and recommendations]. ( Bak, M; Marcelis, M; van Os, J, 2011)
"To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression."4.85Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009)
"To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression."4.82Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005)
"Psychotic disorders are the most frequent psychiatric diagnosis associated with cough mixture abuse."1.38Clinical characteristics of cough mixture abusers referred to three substance abuse clinics in Hong Kong: a retrospective study. ( Chan, F; Liang, HJ; Mak, SC; Tang, AK; Tang, WK; Ungvari, GS, 2012)
"Fluphenazine is shown to be a potent, specific antagonist of the norepinephrine-mediated inhibition of Purkinje cell discharge."1.26Interactions of antipsychotic drugs with norepinephrine and cerebellar neuronal circuitry: implications for the psychobiology of psychosis. ( Freedman, R, 1977)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199018 (60.00)18.7374
1990's0 (0.00)18.2507
2000's2 (6.67)29.6817
2010's9 (30.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Stetson, SR1
Osser, DN1
Jürgens, G1
Bauer, JØ1
Prakash, R1
Aggarwal, N1
Kataria, D1
Prasad, S1
Bak, M2
Weltens, I1
Bervoets, C1
De Fruyt, J1
Samochowiec, J1
Fiorillo, A1
Sampogna, G1
Bienkowski, P1
Preuss, WU1
Misiak, B1
Frydecka, D1
Samochowiec, A1
Bak, E1
Drukker, M1
Dom, G1
Szegő, A1
Eleméry, M1
Faludi, G1
Kovács, G1
Ramamourty, P1
Menon, V1
Aparna, M1
Huf, G3
Alexander, J3
Gandhi, P1
Allen, MH3
Raveendran, NS1
Baldaçara, L1
Sanches, M1
Cordeiro, DC1
Jackoswski, AP1
van Os, J1
Marcelis, M1
Tang, AK1
Tang, WK1
Liang, HJ1
Chan, F1
Mak, SC1
Ungvari, GS1
SHEA, JG1
SCHULTZ, JD1
LEWIS, E1
FAZEKAS, JF1
WALCHER, W1
VISSER, SL1
DERZSI, S1
FENYVESI, T1
VOJTECHOVSKY, M1
MIROUX, M1
Van Sweden, B1
Dumon-Radermecker, M1
Vol'f, MSh1
Freedman, R1
Lipinski, J1
Baldessarini, R1
Thornton, WE1
Thornton, BP1
Kehoe, MJ1
D'Errico, A1
Morello, G1
Turchiaro, G1
Radzuweit, H1
Knorr, W1
Favazza, AR1
Johnson, J1
Milner, G1
Meyer, HH1

Reviews

8 reviews available for promethazine and Psychoses

ArticleYear
Psychopharmacology of agitation in acute psychotic and manic episodes.
    Current opinion in psychiatry, 2022, 05-01, Volume: 35, Issue:3

    Topics: Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Ma

2022
The pharmacological management of agitated and aggressive behaviour: A systematic review and meta-analysis.
    European psychiatry : the journal of the Association of European Psychiatrists, 2019, Volume: 57

    Topics: Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; H

2019
Haloperidol plus promethazine for psychosis-induced aggression.
    The Cochrane database of systematic reviews, 2016, 11-25, Volume: 11

    Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; P

2016
Haloperidol plus promethazine for psychosis-induced aggression.
    The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3

    Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; O

2009
[Rapid tranquillisation; review of the literature and recommendations].
    Tijdschrift voor psychiatrie, 2011, Volume: 53, Issue:10

    Topics: Aggression; Benzodiazepines; Conscious Sedation; Drug Therapy, Combination; Haloperidol; Humans; Hyp

2011
[CHOLINOTROPIC HALLUCINOGENS. II].
    Lekarska veda v zahranici, 1964, Apr-17, Volume: 35

    Topics: Benactyzine; Hallucinogens; Humans; Lysergic Acid Diethylamide; Mental Disorders; Muscle Relaxants,

1964
Haloperidol plus promethazine for psychosis induced aggression.
    The Cochrane database of systematic reviews, 2005, Jan-25, Issue:1

    Topics: Aggression; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; Promethazine; Psyc

2005
II. Major tranquilizers.
    Southern medical journal, 1971, Volume: 64, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Chlorpromazine; Fluphenazine; Hem

1971

Trials

2 trials available for promethazine and Psychoses

ArticleYear
Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone.
    Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2011, Volume: 33, Issue:1

    Topics: Adult; Aggression; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Dru

2011
Trial of a chlorpromazine-promethazine-phenobarbital drug combination in 60 psychiatric cases.
    Panminerva medica, 1966, Volume: 8, Issue:4

    Topics: Adult; Chlorpromazine; Clinical Trials as Topic; Humans; Phenobarbital; Promethazine; Psychotic Diso

1966

Other Studies

20 other studies available for promethazine and Psychoses

ArticleYear
[Haloperidol and promethazine in psychotic aggression].
    Ugeskrift for laeger, 2017, 04-17, Volume: 179, Issue:16

    Topics: Aggression; Antipsychotic Agents; Drug Therapy, Combination; Haloperidol; Humans; Promethazine; Psyc

2017
Meditation induced psychosis: Case report.
    Asian journal of psychiatry, 2018, Volume: 31

    Topics: Adult; Antipsychotic Agents; GABA Modulators; Haloperidol; Humans; Lorazepam; Male; Meditation; Prom

2018
[Emergency psychopharmacotherapy in Hungary -- preliminary data].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2014, Volume: 16, Issue:1

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clopenthixol; Droperidol; Drug Prescript

2014
Koro presenting as acute and transient psychosis: implications for classification.
    Asian journal of psychiatry, 2014, Volume: 10

    Topics: Adult; Antipsychotic Agents; Diagnosis, Differential; Haloperidol; Humans; Koro; Male; Promethazine;

2014
Clinical characteristics of cough mixture abusers referred to three substance abuse clinics in Hong Kong: a retrospective study.
    East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2012, Volume: 22, Issue:4

    Topics: Adult; Antitussive Agents; Azabicyclo Compounds; Codeine; Comorbidity; Diagnosis, Dual (Psychiatry);

2012
[Phenergan therapy of mental disorder and hyperthymic states].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1952, Volume: 129, Issue:10

    Topics: Anti-Allergic Agents; Emotions; Histamine H1 Antagonists; Mental Disorders; Promethazine; Psychotic

1952
The clinical and cerebral action of promethazine and methylphenidate hydrochloride.
    The American journal of the medical sciences, 1958, Volume: 235, Issue:2

    Topics: Counseling; Humans; Medical Records; Mental Disorders; Methylphenidate; Promethazine; Psychoses, Alc

1958
[Neurologic-psychiatric problems of extended 1st aid].
    Wiener medizinische Wochenschrift (1946), 1963, Jan-26, Volume: 113

    Topics: Cerebrovascular Disorders; Chlorpromazine; Epilepsy; First Aid; Humans; Mental Disorders; Meperidine

1963
[A PARADOXICAL REACTION TO NEUROLEPTICS (EXCITOMOTOR SYNDROME)].
    Nederlands tijdschrift voor geneeskunde, 1963, Nov-30, Volume: 107

    Topics: Alcoholism; Antipsychotic Agents; Bipolar Disorder; Brain Diseases; Chlorpromazine; Electroencephalo

1963
HIREPINE IN PSYCHIATRY.
    Therapia Hungarica (English edition), 1964, Volume: 12

    Topics: Catatonia; Chlorpromazine; Convulsive Therapy; Dementia; Depression; Electroconvulsive Therapy; Huma

1964
[Combined action of chlorpromazine, promethazine and of a specific tissue serum].
    Gazette medicale de France, 1955, Volume: 62, Issue:7

    Topics: Anti-Allergic Agents; Chlorpromazine; Electroconvulsive Therapy; Histamine H1 Antagonists; Humans; I

1955
The EEG in chronic psychotropic drug intoxications.
    Clinical EEG (electroencephalography), 1982, Volume: 13, Issue:4

    Topics: Adult; Aged; Amitriptyline; Chlorpromazine; Chlorprothixene; Chronic Disease; Drug Therapy, Combinat

1982
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:3

    Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; C

1975
Interactions of antipsychotic drugs with norepinephrine and cerebellar neuronal circuitry: implications for the psychobiology of psychosis.
    Biological psychiatry, 1977, Volume: 12, Issue:2

    Topics: Action Potentials; Afferent Pathways; Animals; Cerebellum; Dose-Response Relationship, Drug; Drug An

1977
Nonantipsychotic phenothiazines and tardive dyskinesia.
    The New England journal of medicine, 1973, Oct-04, Volume: 289, Issue:14

    Topics: Humans; Movement Disorders; Phenothiazines; Promethazine; Psychotic Disorders; Thiethylperazine; Tim

1973
Letter: Tardive dyskinesia and low dosage.
    The American journal of psychiatry, 1973, Volume: 130, Issue:12

    Topics: Chlorpromazine; Fluphenazine; Humans; Hypnotics and Sedatives; Movement Disorders; Promethazine; Psy

1973
[Influencing of biological and immunologic pregnancy reactions by psychotropic drugs].
    Endokrinologie, 1969, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Butyrophenones; Chlorpromazine; Dementia; Depressive Disorder, Major; Dysau

1969
Promethazine-chlorpromazine combination in the treatment of unmanageable psychotic patients.
    Henry Ford Hospital medical journal, 1969,Winter, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Chlorpromazine; Drug Synergism; Female; Humans; Male; Promethazine; Psychotic Dis

1969
Psychiatric complications of amphetamine substances.
    Acta psychiatrica Scandinavica, 1966, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Amphetamine; Chlordiazepoxide; Depression; Ephedrine; Female; Hall

1966
[On the question of possible irreversible disorders due to psychopharmacotherapy].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1966, Volume: 208, Issue:4

    Topics: Adult; Autonomic Nervous System; Biperiden; Butyrophenones; Central Nervous System; Chlorpromazine;

1966