promethazine has been researched along with Porphyria, Acute Intermittent in 3 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Porphyria, Acute Intermittent: An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The patient was initially treated for her abdominal pain and vomiting." | 1.35 | Drug use in porphyria: a therapeutic dilemma. ( Jimmy, B; Jose, J; Saravu, K; Shastry, BA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jose, J | 1 |
| Saravu, K | 1 |
| Shastry, BA | 1 |
| Jimmy, B | 1 |
| BARKAY, M | 1 |
| THYS, O | 1 |
| DELCROIX, G | 1 |
| DURET, RL | 1 |
| Tishler, PV | 1 |
3 other studies available for promethazine and Porphyria, Acute Intermittent
| Article | Year |
|---|---|
Drug use in porphyria: a therapeutic dilemma.
Topics: Abdominal Pain; Adult; Amines; Anticonvulsants; Antiemetics; Antihypertensive Agents; Chest Pain; Cy | 2008 |
[A CASE OF INTERMITTENT ACUTE PORPHYRIA IN A 52-YEAR-OLD WOMAN, TRIGGERED BY THE INGESTION OF AN ALLYL BARBITURATE].
Topics: Barbiturates; Chlorpromazine; Porphyria, Acute Intermittent; Porphyrias; Promethazine; Sorbitol; Tox | 1964 |
The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria.
Topics: Animals; Chlorpromazine; Diazepam; Enzyme Activation; Erythrocytes; Humans; Hydroxymethylbilane Synt | 1999 |