promethazine has been researched along with Pernicious Vomiting of Pregnancy in 12 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effects of promethazine with those of metoclopramide for hyperemesis gravidarum." | 9.14 | Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. ( Khine, PP; Omar, SZ; Tan, PC; Vallikkannu, N, 2010) |
| "Promethazine reduces the symptoms of hyperemesis gravidarum faster than prednisolone, but during prolonged treatment, prednisolone has at least the same effects on the symptoms and less drug side-effects." | 9.11 | The efficacy low dose of prednisolone in the treatment of hyperemesis gravidarum. ( Faghihzadeh, S; Hosseiney, FS; Ziaei, S, 2004) |
| "We attempted to determine whether the antiemetic ondansetron would be more effective than promethazine in treating hyperemesis gravidarum." | 9.08 | A pilot study of intravenous ondansetron for hyperemesis gravidarum. ( Johnson, CA; Martin, RW; Morrison, JC; Roach, H; Stewart, DK; Sullivan, CA, 1996) |
| "The study compared the efficacy of methylprednisolone with that of promethazine for the treatment of hyperemesis gravidarum." | 9.08 | The efficacy of methylprednisolone in the treatment of hyperemesis gravidarum: a randomized, double-blind, controlled study. ( Alsulyman, OM; Fassett, MJ; Goodwin, TM; Safari, HR; Souter, IC, 1998) |
| "To compare the effects of promethazine with those of metoclopramide for hyperemesis gravidarum." | 5.14 | Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. ( Khine, PP; Omar, SZ; Tan, PC; Vallikkannu, N, 2010) |
| "Promethazine reduces the symptoms of hyperemesis gravidarum faster than prednisolone, but during prolonged treatment, prednisolone has at least the same effects on the symptoms and less drug side-effects." | 5.11 | The efficacy low dose of prednisolone in the treatment of hyperemesis gravidarum. ( Faghihzadeh, S; Hosseiney, FS; Ziaei, S, 2004) |
| "This study compares pyridoxine-metoclopramide combination therapy to prochlorperazine and promethazine monotherapies in the outpatient treatment of nausea and vomiting in pregnancy." | 5.10 | Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy. ( Bsat, FA; Hoffman, DE; Seubert, DE, 2003) |
| "We attempted to determine whether the antiemetic ondansetron would be more effective than promethazine in treating hyperemesis gravidarum." | 5.08 | A pilot study of intravenous ondansetron for hyperemesis gravidarum. ( Johnson, CA; Martin, RW; Morrison, JC; Roach, H; Stewart, DK; Sullivan, CA, 1996) |
| "The study compared the efficacy of methylprednisolone with that of promethazine for the treatment of hyperemesis gravidarum." | 5.08 | The efficacy of methylprednisolone in the treatment of hyperemesis gravidarum: a randomized, double-blind, controlled study. ( Alsulyman, OM; Fassett, MJ; Goodwin, TM; Safari, HR; Souter, IC, 1998) |
| "Hyperemesis gravidarum is a severe form of nausea and vomiting in pregnancy affecting 0." | 2.53 | Interventions for treating hyperemesis gravidarum. ( Barton, SJ; Berghella, V; Boelig, RC; Edwards, SJ; Kelly, AJ; Saccone, G, 2016) |
| "Of note, co-existing gastroesophageal reflux disease (GERD), Helicobacter pylori infection, and psychosocial factors may have a negative impact on the management of NVP." | 2.50 | The outpatient management and special considerations of nausea and vomiting in pregnancy. ( Clark, SM; Dutta, E; Hankins, GD, 2014) |
| "Early pregnancy is characterized by nausea and vomiting which are the most frequent symptoms and the main reason for consulting the physician." | 2.41 | [Evaluation and treatment of hyperemesis gravidarum]. ( Accorsi, P; Aguzzoli, L; Carossino, E; Crotti, M; Gargano, G; Masellis, G, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clark, SM | 1 |
| Dutta, E | 1 |
| Hankins, GD | 1 |
| Boelig, RC | 1 |
| Barton, SJ | 1 |
| Saccone, G | 1 |
| Kelly, AJ | 1 |
| Edwards, SJ | 1 |
| Berghella, V | 1 |
| Tan, PC | 1 |
| Khine, PP | 1 |
| Vallikkannu, N | 1 |
| Omar, SZ | 1 |
| RHODES, P | 1 |
| Bsat, FA | 1 |
| Hoffman, DE | 1 |
| Seubert, DE | 1 |
| Ziaei, S | 1 |
| Hosseiney, FS | 1 |
| Faghihzadeh, S | 1 |
| Magee, LA | 1 |
| Redman, CW | 1 |
| Sullivan, CA | 1 |
| Johnson, CA | 1 |
| Roach, H | 1 |
| Martin, RW | 1 |
| Stewart, DK | 1 |
| Morrison, JC | 1 |
| Safari, HR | 1 |
| Fassett, MJ | 1 |
| Souter, IC | 1 |
| Alsulyman, OM | 1 |
| Goodwin, TM | 1 |
| Crotti, M | 1 |
| Aguzzoli, L | 1 |
| Carossino, E | 1 |
| Accorsi, P | 1 |
| Gargano, G | 1 |
| Masellis, G | 1 |
| Ghatikar, KN | 1 |
| Pestel, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622] | Phase 2 | 3 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Lack of recruitment) | ||
| IRB-HSR# 14583: Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients[NCT01414777] | Phase 2/Phase 3 | 68 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for promethazine and Pernicious Vomiting of Pregnancy
| Article | Year |
|---|---|
The outpatient management and special considerations of nausea and vomiting in pregnancy.
Topics: Ambulatory Care; Antiemetics; Diet Therapy; Doxylamine; Female; Fluid Therapy; Gastroesophageal Refl | 2014 |
Interventions for treating hyperemesis gravidarum.
Topics: Acupuncture Therapy; Adrenal Cortex Hormones; Antiemetics; Female; Humans; Hydrocortisone; Hyperemes | 2016 |
[Evaluation and treatment of hyperemesis gravidarum].
Topics: Administration, Oral; Adult; Antiemetics; Birth Weight; Chlorpromazine; Diagnosis, Differential; Fem | 2001 |
6 trials available for promethazine and Pernicious Vomiting of Pregnancy
| Article | Year |
|---|---|
Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial.
Topics: Adult; Antiemetics; Double-Blind Method; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Pre | 2010 |
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramid | 2003 |
The efficacy low dose of prednisolone in the treatment of hyperemesis gravidarum.
Topics: Administration, Oral; Adolescent; Adult; Confidence Intervals; Dose-Response Relationship, Drug; Dru | 2004 |
An N-of-1 trial for treatment of hyperemesis gravidarum.
Topics: Adult; Antiemetics; Ascorbic Acid; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hy | 1996 |
A pilot study of intravenous ondansetron for hyperemesis gravidarum.
Topics: Adult; Antiemetics; Double-Blind Method; Female; Humans; Hyperemesis Gravidarum; Injections, Intrave | 1996 |
The efficacy of methylprednisolone in the treatment of hyperemesis gravidarum: a randomized, double-blind, controlled study.
Topics: Adult; Double-Blind Method; Female; Gestational Age; Humans; Hyperemesis Gravidarum; Male; Methylpre | 1998 |
3 other studies available for promethazine and Pernicious Vomiting of Pregnancy
| Article | Year |
|---|---|
HYPEREMESIS GRAVIDARUM.
Topics: Blood Chemical Analysis; Female; Humans; Hyperemesis Gravidarum; Meclizine; Nausea; Pathology; Pregn | 1964 |
Drugs for hyperemesis gravidarum.
Topics: Female; Humans; Hyperemesis Gravidarum; Pregnancy; Pregnancy Trimester, First; Promethazine | 1988 |
[New drugs for nausea and vomiting. A clinical and physiological study].
Topics: Adult; Anesthesia; Antiemetics; Atropa belladonna; Barbiturates; Child; Chlorpromazine; Cyclizine; F | 1969 |