promethazine and Parkinsonian Disorders
promethazine has been researched along with Parkinsonian Disorders in 6 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Promethazine (PMZ) is an FDA-approved antihistaminergic drug that was identified as a potentially neuroprotective compound in the NINDS screening program." | 1.33 | Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. ( Beal, MF; Calingasan, NY; Chen, J; Cleren, C; Lorenzo, BJ; Starkov, AA, 2005) |
Research
Studies (6)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (83.33) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
TOLAN, EJ | 1 |
OLARIU, J | 1 |
GERSTENBRAND, F | 1 |
PATEISKY, K | 1 |
STJEAN, A | 1 |
DONALD, M | 1 |
BAN, TA | 1 |
BOVET, D | 1 |
DUREL, P | 1 |
LONGO, V | 1 |
WINTHER, K | 1 |
Cleren, C | 1 |
Starkov, AA | 1 |
Calingasan, NY | 1 |
Lorenzo, BJ | 1 |
Chen, J | 1 |
Beal, MF | 1 |
Other Studies
6 other studies available for promethazine and Parkinsonian Disorders
Article | Year |
---|---|
Treatment of parkinsonism; preliminary report on use of promethazine in 12 cases.
Topics: Humans; Parkinson Disease; Parkinsonian Disorders; Promethazine | 1957 |
[CONTRIBUTION TO THE THERAPY AND REHABILITATION OF PARKINSON'S SYNDROME].
Topics: Histamine H1 Antagonists; Neurosurgery; Orphenadrine; Parasympatholytics; Parkinson Disease; Parkins | 1963 |
INTERCHANGEABLITY OF ANTIPARKINSONIAN MEDICATION.
Topics: Antiparkinson Agents; Biomedical Research; Extrapyramidal Tracts; Geriatrics; Humans; Parasympatholy | 1964 |
[Antagonism of dibenzothiazine derivatives (diparcol, parsidol, phenergan) towards the central effects of nicotine; correspondence with clinical experimentation in Parkinson's disease].
Topics: Empirical Research; Histamine Antagonists; Nicotine; Parkinson Disease; Parkinsonian Disorders; Phen | 1950 |
[Treatment of paralysis agitans with some new preparations: parpanit, diparcol, and phenergan].
Topics: Cyclopentanes; Histamine; Parkinson Disease; Parkinsonian Disorders; Phenothiazines; Promethazine | 1950 |
Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Calcium; Calcium Signaling; Disease Models, Animal; Dopamine; | 2005 |