promethazine has been researched along with Neuroleptic Malignant Syndrome in 6 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Promethazine was prescribed, and this was the patient's only medication on admission." | 5.30 | Neuroleptic malignant syndrome due to promethazine. ( Chan-Tack, KM, 1999) |
| "We report a case of severe neuroleptic malignant syndrome with hyperthermia, rhabdomyolysis and hepatic failure where we applied endovascular cooling in order to reverse hyperthermia." | 1.35 | Endovascular cooling in a patient with neuroleptic malignant syndrome. ( Diedler, J; Mellado, P; Veltkamp, R, 2008) |
| "Promethazine was prescribed, and this was the patient's only medication on admission." | 1.30 | Neuroleptic malignant syndrome due to promethazine. ( Chan-Tack, KM, 1999) |
| "She underwent hemodialysis for treatment of acute renal failure and recovered from it after 16 sessions of hemodialysis." | 1.28 | [A case of neuroleptic malignant syndrome with acute renal failure]. ( Hayashi, M; Koya, J; Shiono, A; Yajima, H; Yamanaka, H, 1992) |
| "Differentiating neuroleptic malignant syndrome from malignant hyperthermia allows early appropriate treatment with bromocriptine." | 1.28 | Neuroleptic malignant syndrome: occurrence in a child after reconstructive surgery. ( Brown, FE; Nierenberg, DW; Nordgren, RE; Rozycki, AA; Taylor, RM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mendhekar, DN | 1 |
| Andrade, CR | 1 |
| Diedler, J | 1 |
| Mellado, P | 1 |
| Veltkamp, R | 1 |
| Chan-Tack, KM | 1 |
| Duggal, HS | 1 |
| Shiono, A | 1 |
| Hayashi, M | 1 |
| Yamanaka, H | 1 |
| Yajima, H | 1 |
| Koya, J | 1 |
| Brown, FE | 1 |
| Nierenberg, DW | 1 |
| Nordgren, RE | 1 |
| Taylor, RM | 1 |
| Rozycki, AA | 1 |
6 other studies available for promethazine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuroleptic malignant syndrome with promethazine.
Topics: Adult; Antipsychotic Agents; Bromocriptine; Dopamine Agonists; Female; Humans; Neuroleptic Malignant | 2005 |
Endovascular cooling in a patient with neuroleptic malignant syndrome.
Topics: Antipsychotic Agents; Catheters, Indwelling; Creatine Kinase; Drug Synergism; Female; Fever; Haloper | 2008 |
Neuroleptic malignant syndrome due to promethazine.
Topics: Acidosis; Adult; Antiemetics; Arrhythmia, Sinus; Creatine Kinase; Delirium; Fever; Humans; Hypernatr | 1999 |
Neuroleptic malignant syndrome precipitated by promethazine and lorazepam.
Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Basal Ganglia Diseases; Histamine H1 Antagonists; | 2001 |
[A case of neuroleptic malignant syndrome with acute renal failure].
Topics: Acute Kidney Injury; Chlorpromazine; Drug Combinations; Female; Humans; Middle Aged; Neuroleptic Mal | 1992 |
Neuroleptic malignant syndrome: occurrence in a child after reconstructive surgery.
Topics: Child; Ear Cartilage; Female; Humans; Neuroleptic Malignant Syndrome; Postoperative Complications; P | 1991 |