promethazine has been researched along with Nerve Degeneration in 2 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Promethazine (PMZ) is an FDA-approved antihistaminergic drug that was identified as a potentially neuroprotective compound in the NINDS screening program." | 1.33 | Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. ( Beal, MF; Calingasan, NY; Chen, J; Cleren, C; Lorenzo, BJ; Starkov, AA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cleren, C | 1 |
| Starkov, AA | 1 |
| Calingasan, NY | 1 |
| Lorenzo, BJ | 1 |
| Chen, J | 1 |
| Beal, MF | 1 |
| Chumasov, EI | 1 |
| Kolosova, LI | 1 |
| Babin, AV | 1 |
| Svetikova, KM | 1 |
| Akoev, GN | 1 |
2 other studies available for promethazine and Nerve Degeneration
| Article | Year |
|---|---|
Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Calcium; Calcium Signaling; Disease Models, Animal; Dopamine; | 2005 |
[Structural-functional changes in the peripheral nerves after administration of several drugs].
Topics: Action Potentials; Aminopyrine; Animals; Calcium Chloride; Drug Combinations; Electrophysiology; Mal | 1991 |