promethazine has been researched along with Necrosis in 22 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Modifying the toxicity with PM, together with a low dose of CCl4, helped to minimize secondary effects of CCl4, to clarify the sequence of toxic events, and to assess the sensitivity of some standard tests of hepatotoxicity." | 1.27 | Correlations between common tests for assessment of liver damage: indices of the hepatoprotective activity of promethazine in carbon tetrachloride hepatotoxicity. ( Cheeseman, KH; Reddrop, CJ; Slater, TF, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (95.45) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CHADWICK, DA | 1 |
| JENNINGS, RC | 1 |
| MOCHTAR, IA | 2 |
| MULLER, J | 2 |
| VAN CREVEL, D | 1 |
| VAN DER KOLK, WF | 1 |
| PETZOLD, H | 1 |
| ZIMMERMANN, S | 1 |
| AMER, S | 1 |
| JUDAH, JD | 1 |
| AHMED, K | 1 |
| MCLEAN, AE | 1 |
| TAPP, E | 1 |
| CARROLL, R | 1 |
| Selye, H | 1 |
| Bloksma, N | 1 |
| van de Wiel, P | 1 |
| Hofhuis, F | 1 |
| Kuper, F | 1 |
| Willers, J | 1 |
| Reddrop, CJ | 1 |
| Cheeseman, KH | 1 |
| Slater, TF | 2 |
| Faucher, L | 1 |
| Marcoux, D | 1 |
| Foust, RT | 1 |
| Reddy, KR | 1 |
| Jeffers, LJ | 1 |
| Schiff, ER | 1 |
| Poulsen, SS | 1 |
| Nimmo, J | 1 |
| Dixon, MF | 1 |
| Prescott, LF | 1 |
| Kovács, K | 1 |
| Szijj, I | 1 |
| Sträuli, UD | 1 |
| Sawyer, BC | 1 |
| Rohan, P | 1 |
| Tachi, C | 1 |
| Tachi, S | 1 |
| Lindner, HR | 1 |
| Rice, AJ | 1 |
| Plaa, GL | 1 |
| Kaszewska-Jablońska, I | 1 |
| Mostafavi, H | 1 |
| Samimi, M | 1 |
| Serratoni, FT | 1 |
| Schnitzer, B | 1 |
| Smith, EB | 1 |
| Fourrier, A | 1 |
| Camier, P | 1 |
| Leclercq, J | 1 |
22 other studies available for promethazine and Necrosis
| Article | Year |
|---|---|
MASSIVE HEPATIC NECROSIS ASSOCIATED WITH HALOTHANE ANESTHESIA.
Topics: Anesthesia; Atropine; Barbiturates; Chemical and Drug Induced Liver Injury; Colonic Neoplasms; Halot | 1964 |
PURPURA FULMINANS: A CASE WITH RECOVERY.
Topics: Adrenocorticotropic Hormone; Ascorbic Acid; Blood Coagulation Disorders; Diagnosis; Drug Therapy; Fi | 1965 |
PURPURA FULMINANS: A CASE WITH RECOVERY.
Topics: Adrenocorticotropic Hormone; Ascorbic Acid; Blood Coagulation Disorders; Diagnosis; Drug Therapy; Fi | 1965 |
[THE EFFECT OF DIFFERENT SUBSTANCES ON ACUTE CARBON TETRACHLORIDE NECROSIS OF THE RAT LIVER].
Topics: Aspartate Aminotransferases; Blood Chemical Analysis; Carbon Tetrachloride; Carbon Tetrachloride Poi | 1965 |
PROTECTION PROVIDED AGAINST CARBON TETRACHLORIDE AND THIOACETAMIDE POISONING BY STROPHANTHIN-G.
Topics: Amides; Bilirubin; Blood Chemical Analysis; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Ch | 1965 |
TETRACYCLINE ACCUMULATION IN TOXIC LIVER DAMAGE.
Topics: Amides; Calcium; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; | 1965 |
Acute cutaneous necrosis following sensitization by heterologous blood.
Topics: Acetates; Animals; Blood Group Incompatibility; Blood Transfusion; Cats; Cattle; Chlorpromazine; Cri | 1967 |
Role of histamine in the antitumour activity of endotoxin.
Topics: Animals; Cimetidine; Diphenhydramine; Endotoxins; Female; Glycoproteins; Histamine; Mice; Mice, Inbr | 1984 |
Correlations between common tests for assessment of liver damage: indices of the hepatoprotective activity of promethazine in carbon tetrachloride hepatotoxicity.
Topics: Animals; Body Temperature; Carbon Tetrachloride; Fatty Liver; Lipid Metabolism; Lipid Peroxides; Liv | 1983 |
What syndrome is this? Nicolau syndrome.
Topics: Child, Preschool; Chlorpromazine; Drug Eruptions; Erythema; Humans; Injections, Intramuscular; Leg U | 1995 |
Nyquil-associated liver injury.
Topics: Acetaminophen; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Dextromethorphan; Doxylami | 1989 |
Observations on the surface architecture of histamine-induced gastric ulcerations in the guinea pig.
Topics: Animals; Cell Aggregation; Fibrin; Gastric Mucosa; Granulation Tissue; Guinea Pigs; Histamine; Leuko | 1973 |
Effects of mepyramine, promethazine, and hydrocortisone on paracetamol-induced hepatic necrosis in the rat.
Topics: Acetaminophen; Animals; Benzyl Compounds; Chemical and Drug Induced Liver Injury; Ethylenediamines; | 1973 |
Effect of alloxan diabetes and insulin administration on the incidence of pituitary necrosis caused by hexadimethrine bromide in rats.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Heparin Antagonists; Insulin; Mortality; Necrosis; | 1968 |
Changes in liver nucleotide concentrations in experimental liver injury. 1. Carbon tetrachloride poisoning.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Liver; NAD; NADP; N | 1964 |
Protection against ethanol-induced conditioned necrosis.
Topics: Animals; Cyproheptadine; Ethanol; Female; Histamine H1 Antagonists; Injections, Intraperitoneal; Inj | 1968 |
Action of antihistamines on the endometrium and the histamine theory of decidual induction.
Topics: Animals; Decidua; Diphenhydramine; Endometrium; Female; Histamine; Histamine H1 Antagonists; Microsc | 1970 |
The role of triglyceride accumulation and of necrosis in the hemodynamic responses of the isolated perfused rat liver after administration of carbon tetrachloride.
Topics: Acetates; Amides; Animals; Body Temperature; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; C | 1969 |
[Iron of the subcellular fractions of liver tissue. 3. Effect of promethazine on hepatocellular changes in carbon tetrachloride poisoning].
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Iron; Liver; Necrosis; Promethazine; | 1972 |
Accidental intra-arterial injection of promethazine HCl during general anesthesia: report of a case.
Topics: Amputation, Surgical; Anesthesia, General; Finger Joint; Gangrene; Hand; Humans; Hydrochloric Acid; | 1971 |
Promethazine protection in carbon tetrachloride liver injury. An electron microscopic study.
Topics: Animals; Carbon Tetrachloride Poisoning; Endoplasmic Reticulum; Liver; Male; Microscopy, Electron; M | 1969 |
[Necrotic purpura associated with varicella with drug hypersensitivity coagulopathy related to a Schwartzman-Sanarelli phenomenon. Therapeutic consequences].
Topics: Chickenpox; Child; Drug Hypersensitivity; Female; Hemorrhage; Humans; Necrosis; Promethazine; Purpur | 1969 |