Page last updated: 2024-11-03

promethazine and Nausea

promethazine has been researched along with Nausea in 43 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the prevention of opioid-induced nausea and vomiting (OINV) and the relief of moderate to severe acute pain by CL-108, a novel drug combining a low-dose antiemetic (rapid-release promethazine 12."9.30Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi ( Chou, JC; Daniels, SE; Giannakopoulos, HE; Granquist, EJ; Levin, LM; Maibach, H; Muse, DD; Oreadi, D; Papas, AS; Patrick, K; Schachtel, BP; Zuniga, JR, 2019)
"This study was performed to assess whether promethazine has superior vertigo reduction compared with lorazepam in ED patients."9.19Intravenous promethazine versus lorazepam for the treatment of peripheral vertigo in the emergency department: A double blind, randomized clinical trial of efficacy and safety. ( Amini, A; Asadollahi, S; Habibi, T; Heidari, K; Kariman, H; Mansouri, B; Shahrami, A, 2014)
"The authors sought to compare ondansetron and promethazine among emergency department (ED) patients with undifferentiated nausea."9.13Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial. ( Braude, D; Crandall, C, 2008)
"The study was a randomized, double-blind comparison of prochlorperazine (Compazine) and promethazine (Phenergan) for acute ED treatment of gastritis or gastroenteritis."9.09Prochlorperazine versus promethazine for uncomplicated nausea and vomiting in the emergency department: a randomized, double-blind clinical trial. ( Diercks, DB; Ernst, AA; Park, S; Takakuwa, KM; Weiss, SJ, 2000)
"We assessed whether adding promethazine to the syringe containing morphine for patient-controlled analgesia (PCA) decreases nausea after gynecologic surgery."9.07Influence of promethazine on symptom-therapy scores for nausea during patient-controlled analgesia with morphine. ( Freilich, J; O'Connor, TZ; Paige, D; Preble, L; Sevarino, FB; Silverman, DG, 1992)
"The current Tactical Combat Casualty Care (TCCC) Guidelines recommend parenteral promethazine as the single agent for the treatment of opioid-induced nausea and/or vomiting and give a secondary indication of "synergistic analgesic effect."7.81Replacement of Promethazine With Ondansetron for Treatment of Opioid- and Trauma-Related Nausea and Vomiting in Tactical Combat Casualty Care. ( Burrell, E; Butler, FK; Gross, K; Onifer, DJ; Otten, EJ; Patton, R; Russell, RJ; Stockinger, Z, 2015)
"Aprepitant may have some utility in treating refractory nausea caused by gastroparesis."7.78Gastroparesis-associated refractory nausea treated with aprepitant. ( Fahler, J; Leman, BI; Wall, GC, 2012)
"When treating nausea in patients with chronic gastrointestinal syndromes, clinicians may consider trying higher performing treatments first, and forgoing lower performing treatments."5.56Marijuana, Ondansetron, and Promethazine Are Perceived as Most Effective Treatments for Gastrointestinal Nausea. ( Clarke, JO; Fernandez-Becker, N; Garcia, M; Garcia, P; Grewal, D; Kamal, A; Nandwani, M; Neshatian, L; Nguyen, L; Okafor, P; Regalia, K; Sonu, I; Triadafilopoulos, G; Zikos, TA, 2020)
"To evaluate the prevention of opioid-induced nausea and vomiting (OINV) and the relief of moderate to severe acute pain by CL-108, a novel drug combining a low-dose antiemetic (rapid-release promethazine 12."5.30Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi ( Chou, JC; Daniels, SE; Giannakopoulos, HE; Granquist, EJ; Levin, LM; Maibach, H; Muse, DD; Oreadi, D; Papas, AS; Patrick, K; Schachtel, BP; Zuniga, JR, 2019)
"This study was performed to assess whether promethazine has superior vertigo reduction compared with lorazepam in ED patients."5.19Intravenous promethazine versus lorazepam for the treatment of peripheral vertigo in the emergency department: A double blind, randomized clinical trial of efficacy and safety. ( Amini, A; Asadollahi, S; Habibi, T; Heidari, K; Kariman, H; Mansouri, B; Shahrami, A, 2014)
"Our study shows no evidence that ondansetron is superior to metoclopramide and promethazine in reducing nausea in ED adults."5.15A randomized, placebo-controlled trial of ondansetron, metoclopramide, and promethazine in adults. ( Barrett, TW; DiPersio, DM; Jack, M; Jenkins, CA; Lee, P; McCoin, NS; Singleton, LM; Slovis, CM; Storrow, AB; Zhou, C, 2011)
"The authors sought to compare ondansetron and promethazine among emergency department (ED) patients with undifferentiated nausea."5.13Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial. ( Braude, D; Crandall, C, 2008)
"5 mg, nausea and vomiting were relieved at one hour in 74% and 68%, respectively, compared with 59% for intravenous ondansetron 4 mg."5.12No more than necessary: safety and efficacy of low-dose promethazine. ( Caldwell, JB; Moser, JD; Rhule, FJ, 2006)
"This study compares pyridoxine-metoclopramide combination therapy to prochlorperazine and promethazine monotherapies in the outpatient treatment of nausea and vomiting in pregnancy."5.10Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy. ( Bsat, FA; Hoffman, DE; Seubert, DE, 2003)
"The study was a randomized, double-blind comparison of prochlorperazine (Compazine) and promethazine (Phenergan) for acute ED treatment of gastritis or gastroenteritis."5.09Prochlorperazine versus promethazine for uncomplicated nausea and vomiting in the emergency department: a randomized, double-blind clinical trial. ( Diercks, DB; Ernst, AA; Park, S; Takakuwa, KM; Weiss, SJ, 2000)
"We assessed whether adding promethazine to the syringe containing morphine for patient-controlled analgesia (PCA) decreases nausea after gynecologic surgery."5.07Influence of promethazine on symptom-therapy scores for nausea during patient-controlled analgesia with morphine. ( Freilich, J; O'Connor, TZ; Paige, D; Preble, L; Sevarino, FB; Silverman, DG, 1992)
" Although known to interfere with central dopamine mechanisms, it is frequently used in Parkinson's disease to prevent levodopa-induced nausea and vomiting."5.04Metoclopramide and pimozide in Parkinson's disease and levodopa-induced dyskinesias. ( Marsden, CD; Parkes, JD; Tarsy, D, 1975)
"Based on the safety and efficacy of ondansetron, it may be used as a first-line agent for relief of nausea or vomiting for most patient populations in the ED."4.86Antiemetic therapy for nausea and vomiting in the emergency department. ( Amini, R; Hays, DP; Patanwala, AE; Rosen, P, 2010)
"The current Tactical Combat Casualty Care (TCCC) Guidelines recommend parenteral promethazine as the single agent for the treatment of opioid-induced nausea and/or vomiting and give a secondary indication of "synergistic analgesic effect."3.81Replacement of Promethazine With Ondansetron for Treatment of Opioid- and Trauma-Related Nausea and Vomiting in Tactical Combat Casualty Care. ( Burrell, E; Butler, FK; Gross, K; Onifer, DJ; Otten, EJ; Patton, R; Russell, RJ; Stockinger, Z, 2015)
"Aprepitant may have some utility in treating refractory nausea caused by gastroparesis."3.78Gastroparesis-associated refractory nausea treated with aprepitant. ( Fahler, J; Leman, BI; Wall, GC, 2012)
"To determine the incidence of nausea and vomiting after radiofrequency catheter ablation, determine factors related to nausea and vomiting, and evaluate the antiemetic efficacy of promethazine given during the procedure."3.69Nausea and vomiting in patients undergoing radiofrequency catheter ablation. ( Funk, M; Nyström, KV; Tyndall, A, 1997)
"Motion sickness was scaled from 1 (no sickness) to an endpoint of 20, at which time the subject was too sick to continue or was about to vomit."2.71The relation of motion sickness to the spatial-temporal properties of velocity storage. ( Cohen, B; Dai, M; Kunin, M; Raphan, T, 2003)
"Nausea and vomiting is a common and distressing presenting complaint in emergency departments (ED)."2.52Drugs for the treatment of nausea and vomiting in adults in the emergency department setting. ( Egerton-Warburton, D; Furyk, JS; Meek, RA, 2015)
"When treating nausea in patients with chronic gastrointestinal syndromes, clinicians may consider trying higher performing treatments first, and forgoing lower performing treatments."1.56Marijuana, Ondansetron, and Promethazine Are Perceived as Most Effective Treatments for Gastrointestinal Nausea. ( Clarke, JO; Fernandez-Becker, N; Garcia, M; Garcia, P; Grewal, D; Kamal, A; Nandwani, M; Neshatian, L; Nguyen, L; Okafor, P; Regalia, K; Sonu, I; Triadafilopoulos, G; Zikos, TA, 2020)
"Nausea and vomiting are common, but prevalence of antiemetic use in ED patients is unknown."1.43Oligoantiemesis or Inadequate Prescription of Antiemetics in the Emergency Department: A Local and National Perspective. ( Garra, G; Singer, AJ; Thode, HC, 2016)
"We propose that motion sickness is mediated through the orientation properties of velocity storage in the vestibular system that tend to align eye velocity produced by the angular vestibulo-ocular reflex (aVOR) with gravito-inertial acceleration (GIA)."1.32The critical role of velocity storage in production of motion sickness. ( Cohen, B; Dai, M; Raphan, T, 2003)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199020 (46.51)18.7374
1990's4 (9.30)18.2507
2000's7 (16.28)29.6817
2010's10 (23.26)24.3611
2020's2 (4.65)2.80

Authors

AuthorsStudies
Schrager, NL1
Parker, SE1
Werler, MM1
Zikos, TA1
Nguyen, L1
Kamal, A1
Fernandez-Becker, N1
Regalia, K1
Nandwani, M1
Sonu, I1
Garcia, M1
Okafor, P1
Neshatian, L1
Grewal, D1
Garcia, P1
Triadafilopoulos, G1
Clarke, JO1
Zuniga, JR1
Papas, AS1
Daniels, SE1
Patrick, K1
Muse, DD1
Oreadi, D1
Giannakopoulos, HE1
Granquist, EJ1
Levin, LM1
Chou, JC1
Maibach, H1
Schachtel, BP1
Amini, A1
Heidari, K1
Asadollahi, S1
Habibi, T1
Shahrami, A1
Mansouri, B1
Kariman, H1
Furyk, JS2
Meek, R1
McKenzie, S1
Onifer, DJ1
Butler, FK1
Gross, K1
Otten, EJ1
Patton, R1
Russell, RJ1
Stockinger, Z1
Burrell, E1
Zhu, LL1
Chen, M1
Zhou, Q1
Meek, RA1
Egerton-Warburton, D1
Singer, AJ1
Garra, G1
Thode, HC1
Patanwala, AE1
Amini, R1
Hays, DP1
Rosen, P1
Barrett, TW1
DiPersio, DM1
Jenkins, CA1
Jack, M1
McCoin, NS1
Storrow, AB1
Singleton, LM1
Lee, P1
Zhou, C1
Slovis, CM1
Fahler, J1
Wall, GC1
Leman, BI1
Dai, M2
Kunin, M1
Raphan, T2
Cohen, B2
STEARNS, AB1
FREDERICKSON, GC1
CONE, TE1
RHODES, P1
CLARKE, RS1
DUNDEE, JW2
FITZGERALD, JP1
Bsat, FA1
Hoffman, DE1
Seubert, DE1
Moser, JD1
Caldwell, JB1
Rhule, FJ1
Lu, DP1
Lu, WI1
Braude, D1
Crandall, C1
Geist, ET1
Gross, BD1
Schatz, H1
Farkos, WS1
Buzdar, AU1
Esparza, L1
Natale, R1
Cody, R1
Calzone, K1
Benson, AB1
Sheehan, T1
Berry, W1
Tarkkila, P1
Törn, K1
Tuominen, M1
Lindgren, L1
Tyndall, A1
Nyström, KV1
Funk, M1
Ernst, AA1
Weiss, SJ1
Park, S1
Takakuwa, KM1
Diercks, DB1
Tarsy, D2
Parkes, JD2
Marsden, CD2
Wood, CD1
Silverman, DG1
Freilich, J1
Sevarino, FB1
Paige, D1
Preble, L1
O'Connor, TZ1
Vella, L1
Francis, D1
Houlton, P1
Reynolds, F1
Pestel, M1
Brenner, WE1
Hendricks, CH1
Braaksma, JT1
Fishburne, JI1
Staurovsky, LG1
Ahlgren, P1
Delilkan, AE1
Chandran, S1
Steele, PR1
Masheter, HC1
Isaac, M1
Pandit, SK1
Galway, JE1
Wolff, JD1
Lionarons, HB1
Mesdag, MJ1
Knape, H1
Jones, WM1
Samis, WD1
Macdonald, D1
Boyes, HW1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Isopropyl Alcohol Inhalation as Anti-emetic Therapy in the Emergency Department[NCT04464915]0 participants (Actual)Interventional2020-07-31Withdrawn (stopped due to Given the COVID-19 pandemic, there has been a temporary suspension of study activities, therefore the study has not yet been initiated.)
Effect of Ketamine Versus Sevoflurane On The Right Ventricular Pressure During Congenital Pulmonary Stenosis Balloon Dilatation[NCT05582213]40 participants (Actual)Interventional2022-10-01Completed
Value of Ondansetron Medication vs Inhaled Isopropyl Therapy in the Emergency Department (VOMIITED)[NCT03125811]Early Phase 1121 participants (Actual)Interventional2017-07-17Completed
A Randomized, Double Blind, and Placebo-Controlled Trial Comparing Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult Emergency Department.[NCT00655642]171 participants (Actual)Interventional2007-03-31Terminated (stopped due to Conditional analysis showed observed differences were significantly less than power calculations)
A Randomized Controlled Trial of Ondansetron and Promethazine in the Treatment of Nausea and Vomiting in the Emergency Department[NCT00429832]Phase 4120 participants Interventional2003-10-31Completed
A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622]Phase 23 participants (Actual)Interventional2014-07-31Terminated (stopped due to Lack of recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Visual Analog Scale (VAS) Score for Nausea. This Was Calculated by Subtracting the Patient's Reported Score on the 30 Minute VAS From the Patient's Reported VAS Score on Their Baseline VAS.

"Participants independently rated their nausea severity on separate scales at the baseline and 30-minute evaluations to prevent the baseline VAS score from influencing the 30-minute mark. The VAS had the words Least Severe on the left and Most Severe on the right. The possible values range from 0 to 100mm with 0 at the Least Severe extreme and 100 at the Most Severe extreme. Investigators instructed the participant to draw a single vertical line through the point on the 100mm scale that corresponded to their nausea severity at the times of measurement (Baseline and 30 minutes)." (NCT00655642)
Timeframe: Baseline and 30 minute assessments

Interventionmillimeter (Median)
Ondansetron-22.0
Metoclopramide-30.0
Promethazine-29.0
Placebo-16.0

Reviews

2 reviews available for promethazine and Nausea

ArticleYear
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N

2015
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N

2015
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N

2015
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N

2015
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N

2015
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N

2015
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N

2015
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N

2015
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
    The Cochrane database of systematic reviews, 2015, Sep-28, Issue:9

    Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N

2015
Antiemetic therapy for nausea and vomiting in the emergency department.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:3

    Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; P

2010
Antiemetic therapy for nausea and vomiting in the emergency department.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:3

    Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; P

2010
Antiemetic therapy for nausea and vomiting in the emergency department.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:3

    Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; P

2010
Antiemetic therapy for nausea and vomiting in the emergency department.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:3

    Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; P

2010

Trials

16 trials available for promethazine and Nausea

ArticleYear
Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi
    Pain medicine (Malden, Mass.), 2019, 12-01, Volume: 20, Issue:12

    Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Analgesics, Opioid; Antiemetics; Drug Combinations; Fe

2019
Intravenous promethazine versus lorazepam for the treatment of peripheral vertigo in the emergency department: A double blind, randomized clinical trial of efficacy and safety.
    Journal of vestibular research : equilibrium & orientation, 2014, Volume: 24, Issue:1

    Topics: Double-Blind Method; Female; Humans; Injections, Intravenous; Lorazepam; Male; Middle Aged; Nausea;

2014
A randomized, placebo-controlled trial of ondansetron, metoclopramide, and promethazine in adults.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:3

    Topics: Adult; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Male; Metoclop

2011
A randomized, placebo-controlled trial of ondansetron, metoclopramide, and promethazine in adults.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:3

    Topics: Adult; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Male; Metoclop

2011
A randomized, placebo-controlled trial of ondansetron, metoclopramide, and promethazine in adults.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:3

    Topics: Adult; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Male; Metoclop

2011
A randomized, placebo-controlled trial of ondansetron, metoclopramide, and promethazine in adults.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:3

    Topics: Adult; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Male; Metoclop

2011
The relation of motion sickness to the spatial-temporal properties of velocity storage.
    Experimental brain research, 2003, Volume: 151, Issue:2

    Topics: Adult; Antiemetics; Cross-Over Studies; Dizziness; Double-Blind Method; Eye Movements; Female; Head

2003
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
    Journal of perinatology : official journal of the California Perinatal Association, 2003, Volume: 23, Issue:7

    Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramid

2003
No more than necessary: safety and efficacy of low-dose promethazine.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:1

    Topics: Antiemetics; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Male; Middle

2006
Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2008, Volume: 15, Issue:3

    Topics: Adult; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Follow-Up Studies; Hum

2008
Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2008, Volume: 15, Issue:3

    Topics: Adult; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Follow-Up Studies; Hum

2008
Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2008, Volume: 15, Issue:3

    Topics: Adult; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Follow-Up Studies; Hum

2008
Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2008, Volume: 15, Issue:3

    Topics: Adult; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Follow-Up Studies; Hum

2008
Lorazepam-enhancement of the antiemetic efficacy of dexamethasone and promethazine. A placebo-controlled study.
    American journal of clinical oncology, 1994, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Double-Blind Method; Dru

1994
Premedication with promethazine and transdermal scopolamine reduces the incidence of nausea and vomiting after intrathecal morphine.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:7

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; Anesth

1995
Prochlorperazine versus promethazine for uncomplicated nausea and vomiting in the emergency department: a randomized, double-blind clinical trial.
    Annals of emergency medicine, 2000, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antiemetics; Double-Blind Method; Emergency Service,

2000
Letter: Metoclopramide in parkinsonism.
    Lancet (London, England), 1975, May-31, Volume: 1, Issue:7918

    Topics: Clinical Trials as Topic; Humans; Levodopa; Metoclopramide; Nausea; Parkinson Disease; Promethazine;

1975
Metoclopramide and pimozide in Parkinson's disease and levodopa-induced dyskinesias.
    Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:4

    Topics: Aged; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Interactions; Drug Therapy, Combina

1975
Influence of promethazine on symptom-therapy scores for nausea during patient-controlled analgesia with morphine.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:5

    Topics: Adult; Analgesia, Patient-Controlled; Droperidol; Female; Humans; Middle Aged; Morphine; Nausea; Pat

1992
Comparison of the antiemetics metoclopramide and promethazine in labour.
    British medical journal (Clinical research ed.), 1985, Apr-20, Volume: 290, Issue:6476

    Topics: Clinical Trials as Topic; Consciousness; Double-Blind Method; Female; Humans; Meperidine; Metoclopra

1985
Cataract extractions without tracheal intubation.
    Canadian Anaesthetists' Society journal, 1974, Volume: 21, Issue:4

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Atropine; Carbon Dioxide; Cataract Ext

1974
Phenoperidine and droperidol as premedicants. A controlled study in ophthalmic surgical procedures in combination with retrobulbar block.
    Anaesthesia, 1971, Volume: 26, Issue:3

    Topics: Aged; Amnesia; Analgesics; Benperidol; Female; Humans; Hypotension; Injections, Intramuscular; Injec

1971

Other Studies

25 other studies available for promethazine and Nausea

ArticleYear
The association of nausea and vomiting of pregnancy, its treatments, and select birth defects: Findings from the National Birth Defect Prevention Study.
    Birth defects research, 2023, 02-01, Volume: 115, Issue:3

    Topics: Cleft Palate; Craniosynostoses; Female; Humans; Microphthalmos; Nausea; Pregnancy; Pregnancy Complic

2023
Marijuana, Ondansetron, and Promethazine Are Perceived as Most Effective Treatments for Gastrointestinal Nausea.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Cannabis; Chronic Disease; Comparative Effe

2020
Drug treatment of adults with nausea and vomiting in primary care.
    BMJ (Clinical research ed.), 2014, Aug-07, Volume: 349

    Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopra

2014
Replacement of Promethazine With Ondansetron for Treatment of Opioid- and Trauma-Related Nausea and Vomiting in Tactical Combat Casualty Care.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2015,Summer, Volume: 15, Issue:2

    Topics: Analgesics, Opioid; Antiemetics; Emergency Service, Hospital; Humans; Military Medicine; Nausea; Off

2015
Is Promethazine 6.25 mg Intravenous Dose Really Ideal to Treat Postoperative Nausea and Vomiting?
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2015, Volume: 30, Issue:4

    Topics: Antiemetics; Double-Blind Method; Humans; Nausea; Postoperative Complications; Postoperative Nausea

2015
Oligoantiemesis or Inadequate Prescription of Antiemetics in the Emergency Department: A Local and National Perspective.
    The Journal of emergency medicine, 2016, Volume: 50, Issue:6

    Topics: Adult; Antiemetics; Emergency Service, Hospital; Female; Humans; Logistic Models; Male; Metocloprami

2016
Gastroparesis-associated refractory nausea treated with aprepitant.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:12

    Topics: Abdominal Pain; Adult; Antiemetics; Aprepitant; Female; Follow-Up Studies; Gastroparesis; Humans; Mo

2012
Promethazione hydrochloride for the control of nausea and vomiting during spinal anesthesia.
    The Illinois medical journal, 1957, Volume: 112, Issue:6

    Topics: Anesthesia; Anesthesia, Spinal; Anesthesiology; Humans; Nausea; Promethazine; Vomiting

1957
Promethazine suppositories for management of nausea and vomiting in children.
    A.M.A. journal of diseases of children, 1958, Volume: 95, Issue:4

    Topics: Child; Disease Management; Humans; Infant; Nausea; Promethazine; Suppositories; Vomiting

1958
HYPEREMESIS GRAVIDARUM.
    The Practitioner, 1964, Volume: 192

    Topics: Blood Chemical Analysis; Female; Humans; Hyperemesis Gravidarum; Meclizine; Nausea; Pathology; Pregn

1964
CLINICAL STUDIES ON INDUCTION AGENTS. XII. THE INFLUENCE OF SOME PREMEDICANTS ON THE COURSE AND SEQUELAE OF PROPANIDID ANAESTHESIA.
    British journal of anaesthesia, 1965, Volume: 37

    Topics: Anesthesia; Anesthesia, Intravenous; Anesthetics; Antiemetics; Atropine; Curettage; Cyclizine; Femal

1965
The effect of promethazine in nausea and vomiting of pregnancy.
    The New Zealand medical journal, 1955, Volume: 54, Issue:300

    Topics: Female; Histamine H1 Antagonists; Nausea; Pregnancy; Pregnancy Complications; Promethazine; Vomiting

1955
The critical role of velocity storage in production of motion sickness.
    Annals of the New York Academy of Sciences, 2003, Volume: 1004

    Topics: Adult; Cross-Over Studies; Dizziness; Double-Blind Method; Eye Movements; Female; Head Movements; Hi

2003
Practical oral sedation in dentistry. Part II--Clinical application of various oral sedatives and discussion.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2006, Volume: 27, Issue:9

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Anesthesia, Dental; Child; Child,

2006
Reduction of ketamine-induced emergence phenomena by preoperative promethazine.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1982, Volume: 40, Issue:9

    Topics: Child; Child, Preschool; Double-Blind Method; Hallucinations; Humans; Ketamine; Nausea; Promethazine

1982
Nausea from fluorescein angiography.
    American journal of ophthalmology, 1982, Volume: 93, Issue:3

    Topics: Female; Fluorescein Angiography; Fluoresceins; Humans; Male; Middle Aged; Nausea; Promethazine

1982
Nausea and vomiting in patients undergoing radiofrequency catheter ablation.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 1997, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anesthetics, Intravenous; Antiemetics; Cath

1997
Antimotion sickness and antiemetic drugs.
    Drugs, 1979, Volume: 17, Issue:6

    Topics: Antiemetics; Cyclizine; Dextroamphetamine; Dimenhydrinate; Drug Combinations; Ephedrine; Humans; Mot

1979
[New drugs for nausea and vomiting. A clinical and physiological study].
    La Presse medicale, 1969, May-24, Volume: 77, Issue:25

    Topics: Adult; Anesthesia; Antiemetics; Atropa belladonna; Barbiturates; Child; Chlorpromazine; Cyclizine; F

1969
Intra-amniotic administration of prostaglandin F 2 for induction of therapeutic abortion. A comparison of four dosage schedules.
    The Journal of reproductive medicine, 1972, Volume: 9, Issue:6

    Topics: Abortion, Therapeutic; Adolescent; Adult; Amniotic Fluid; Dose-Response Relationship, Drug; Female;

1972
Dimer-X. A new contrast medium for lumbar myelography without spinal anaesthesia.
    Acta radiologica: diagnosis, 1972, Volume: 13, Issue:0

    Topics: Fever; Fluoroscopy; Headache; Humans; Injections, Spinal; Iothalamic Acid; Lumbar Vertebrae; Myelogr

1972
Intravenous ethanol anaesthesia. A study of sequelae and their implications.
    Acta anaesthesiologica Scandinavica, 1971, Volume: 15, Issue:3

    Topics: Alcohol Deterrents; Alcoholic Intoxication; Amnesia; Anesthesia, Intravenous; Atropine; Barbiturates

1971
The effect of haloperidol with promethazine on postoperative vomiting.
    Archivum chirurgicum Neerlandicum, 1970, Volume: 22, Issue:4

    Topics: Anesthesia, General; Atropine; Haloperidol; Humans; Nausea; Promethazine; Vomiting

1970
A comparison of neuroleptanesthesia and halothane in neurosurgery.
    Archivum chirurgicum Neerlandicum, 1970, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Blood Pressure; Child; Consciousness; Female; Fenta

1970
Anaesthesia for intraocular surgery.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1968, Volume: 3, Issue:4

    Topics: Aged; Anesthesia; Anesthesia, Intravenous; Anesthesia, Local; Cataract Extraction; Eye Diseases; Fem

1968