promethazine has been researched along with Muscle Contraction in 29 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to evaluate the antiulcer activity of Linum usitatissimum fixed oil against aspirin-, indomethacin-, ethanol-, reserpine-, serotonin- and stress-induced gastric ulceration in rats and histamine-induced gastric ulceration in guinea pigs." | 3.76 | Evaluation of antiulcer and antisecretory potential of Linum usitatissimum fixed oil and possible mechanism of action. ( Kaithwas, G; Majumdar, DK, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (72.41) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (13.79) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Dempsey, LM | 2 |
| Kavanagh, JJ | 2 |
| Joseph, N | 1 |
| Tom Esther, NL | 1 |
| Télesphore Benoît, N | 1 |
| Paul Désiré, DD | 1 |
| Oumarou Bibi-Farouck, A | 1 |
| Théophile, D | 1 |
| Pierre, K | 1 |
| Wong, KKL | 1 |
| Tang, LCY | 1 |
| Zhou, J | 1 |
| Ho, V | 1 |
| Kaithwas, G | 1 |
| Majumdar, DK | 1 |
| Aworet-Samseny, RR | 1 |
| Souza, A | 1 |
| Kpahé, F | 1 |
| Konaté, K | 1 |
| Datté, JY | 1 |
| TURCZYNSKI, T | 1 |
| WAWRZEWICZ, M | 1 |
| ZOURLAS, PA | 1 |
| JUDAH, JD | 1 |
| WILLOUGHBY, DA | 1 |
| Khodorova, AB | 1 |
| Nechaeva, MV | 1 |
| Turpaev, TM | 1 |
| Amos, S | 1 |
| Akah, PA | 1 |
| Odukwe, CJ | 1 |
| Gamaniel, KS | 1 |
| Wambede, C | 1 |
| Ladeira, AM | 1 |
| Andrade, SO | 1 |
| Sawaya, P | 1 |
| Nolan, JC | 1 |
| Stephens, DJ | 1 |
| Proakis, AG | 1 |
| Leonard, CA | 1 |
| Johnson, DN | 1 |
| Kilpatrick, BF | 1 |
| Foxwell, MH | 1 |
| Yanni, JM | 1 |
| Labat, C | 1 |
| Cerrina, J | 1 |
| Raffestin, B | 1 |
| Brink, C | 1 |
| Simpson, BR | 1 |
| Strunin, L | 1 |
| Savege, TM | 1 |
| Walton, B | 1 |
| Foley, EI | 1 |
| Maxwell, MP | 1 |
| Ross, LA | 1 |
| Harris, DM | 1 |
| Kuritzky, B | 1 |
| Goodfriend, L | 1 |
| Marcelle, R | 1 |
| Laurent, B | 1 |
| Tozzi, S | 1 |
| Altura, BM | 2 |
| Altura, BT | 1 |
| Bueno, JR | 1 |
| Nogueira de Castro, NJ | 1 |
| Sollero, L | 1 |
| Leszkovszky, GP | 1 |
| Korbonits, D | 1 |
| Greene, MJ | 1 |
| Hughes, MJ | 1 |
| Coret, IA | 1 |
| Osman, OH | 1 |
| Ismail, M | 1 |
| el-Asmar, MF | 1 |
| Ibrahim, SA | 1 |
| Tollackson, KA | 1 |
| Frick, OL | 1 |
| Zakut, H | 1 |
| Mannor, SM | 1 |
| Serr, DM | 1 |
| Ruiz-Veslasco, V | 1 |
| Abramchenko, VV | 1 |
2 trials available for promethazine and Muscle Contraction
| Article | Year |
|---|---|
Muscarinic acetylcholine activity modulates cortical silent period, but not motor evoked potentials, during muscle contractions.
Topics: Acetylcholine; Adult; Cholinergic Agents; Electric Stimulation; Electromyography; Evoked Potentials, | 2023 |
Muscarinic receptor blockade causes postcontraction enhancement in corticospinal excitability following maximal contractions.
Topics: Action Potentials; Adult; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Electromyog | 2021 |
27 other studies available for promethazine and Muscle Contraction
| Article | Year |
|---|---|
Effects of the aqueous extract of Pittosporum mannii Hook. f. (Pittosporaceae) stem barks on spontaneous and spasmogen-induced contractile activity of isolated rat duodenum.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Duodenum; Histamine; Histamine Antag | 2015 |
Analysis of spatiotemporal pattern and quantification of gastrointestinal slow waves caused by anticholinergic drugs.
Topics: Animals; Benztropine; Cholinergic Antagonists; Fourier Analysis; Gastrointestinal Motility; Image Pr | 2017 |
Evaluation of antiulcer and antisecretory potential of Linum usitatissimum fixed oil and possible mechanism of action.
Topics: Acetylcholine; Animals; Aspirin; Atropine; Cholinergic Antagonists; Cimetidine; Ethanol; Flax; Gastr | 2010 |
Dichrostachys cinerea (L.) Wight et Arn (Mimosaceae) hydro-alcoholic extract action on the contractility of tracheal smooth muscle isolated from guinea-pig.
Topics: Animals; Asthma; Atropine; Dose-Response Relationship, Drug; Fabaceae; Guinea Pigs; Histamine; Hista | 2011 |
[Effect of phenergan on contractile function of uterus in the second half of pregnancy].
Topics: Anti-Allergic Agents; Female; Histamine H1 Antagonists; Humans; Muscle Contraction; Pregnancy; Prome | 1956 |
IN VITRO AND IN VIVO EFFECTS OF PROMETHAZINE HYDROCHLORIDE ON HUMAN UTERINE CONTRACTILITY.
Topics: Biomedical Research; Female; Humans; In Vitro Techniques; Labor, Obstetric; Muscle Contraction; Oxyt | 1964 |
INHIBITORS OF SODIUM DEPENDENT RELAXATION OF GUINEA-PIG ILEUM.
Topics: Calcium; Dibucaine; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Ileum; Muscle Contractio | 1964 |
[Possible involvement of histamine in humoral regulation of the spontaneous contractile activity of the chick embryo amnion].
Topics: Amnion; Animals; Chick Embryo; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagon | 1997 |
The pharmacological effects of an aqueous extract from Acacia nilotica seeds.
Topics: Acacia; Acetylcholine; Animals; Atropine; Blood Pressure; Cats; Dose-Response Relationship, Drug; Gu | 1999 |
Studies on Dieffenbachia picta Schott: toxic effects in guinea pigs.
Topics: Animals; Chlorpheniramine; Chymotrypsin; Guinea Pigs; Ileum; In Vitro Techniques; Lethal Dose 50; Mu | 1975 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; C | 1989 |
Effects of thiazinamium chloride on human isolated bronchial muscle preparations.
Topics: Atropine; Bronchi; Bronchodilator Agents; Histamine H1 Antagonists; Humans; In Vitro Techniques; Mus | 1989 |
An azobis-arylimidazo-pyridinium derivative: a rapidly acting non-depolarising muscle-relaxant. Clinical study.
Topics: Adjuvants, Anesthesia; Anesthesia, General; Azo Compounds; Cardiovascular System; Electric Stimulati | 1972 |
Monkey SRS-A. Immunological release from lung and skin fragments. Gel filtration properties and molecular weight estimation.
Topics: Animals; Bradykinin; Chromatography, Gel; Ethanol; Haplorhini; Histamine Release; Ileum; Immune Sera | 1974 |
[Reactivity of human bronchi in vitro].
Topics: Acetylcholine; Airway Resistance; Atropine; Bradykinin; Bronchi; Cromolyn Sodium; Histamine; Histami | 1973 |
The mechanism of action of histamine on the isolated rat uterus.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Antagonists; In | 1973 |
Contractile actions of antihistamines on isolated arterial smooth muscle.
Topics: Acetylcholine; Anesthetics, Local; Animals; Aorta, Thoracic; Atropine; Calcium; Chlorpheniramine; Di | 1974 |
Effects of guanoxan on intestinal smooth muscles.
Topics: Animals; Antihypertensive Agents; Atropine; Dogs; Duodenum; Guinea Pigs; Hexamethonium Compounds; Il | 1968 |
[On the pharmacology of new isoquinoline derivatives].
Topics: Anesthetics, Local; Animals; Antihypertensive Agents; Atropine; Barbiturates; Blood Pressure; Centra | 1967 |
Contractile responses of microvascular smooth muscle to antihistamines.
Topics: Animals; Calcium; Capillaries; Chlorpheniramine; Diphenhydramine; Endotoxins; Epinephrine; Female; H | 1970 |
Some aspects of the pharmacology of droperidol.
Topics: Acetylcholine; Analgesia; Anesthesia, Local; Animals; Behavior, Animal; Benperidol; Drug Synergism; | 1972 |
On specificity of histamine receptors in the heart.
Topics: Animals; Heart; Heart Atria; Heart Rate; Histamine; In Vitro Techniques; Muscle Contraction; Myocard | 1972 |
Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus.
Topics: Animals; Atropine; Chlorpheniramine; Cocaine; Diphenhydramine; Estrus; Female; Hexamethonium Compoun | 1972 |
Response of human smooth muscle in Schultz-Dale experiments.
Topics: Allergens; Anaphylaxis; Antigen-Antibody Reactions; Atropine; Desensitization, Immunologic; Female; | 1966 |
[Effect of promethazine on uterine contractions].
Topics: Drug Antagonism; Drug Synergism; Female; Humans; Labor, Obstetric; Meperidine; Muscle Contraction; O | 1970 |
Analgesia during labor with pentazocine, promazine, promethazine and scopolamine.
Topics: Age Factors; Analgesia; Analgesics; Body Weight; Drug Synergism; Female; Fetus; Humans; Infant, Newb | 1971 |
[Experience in the use of pipolphen and promedol for painless childbirth].
Topics: Analgesics; Anesthesia, Obstetrical; Female; Humans; Muscle Contraction; Piperidines; Pregnancy; Pro | 1966 |