Page last updated: 2024-11-03

promethazine and Mental Disorders

promethazine has been researched along with Mental Disorders in 24 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
" Midazolam was more rapidly sedating than haloperidol-promethazine, reducing the time people are exposed to aggression."5.10Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine. ( , 2003)
"Psychotic disorders are the most frequent psychiatric diagnosis associated with cough mixture abuse."1.38Clinical characteristics of cough mixture abusers referred to three substance abuse clinics in Hong Kong: a retrospective study. ( Chan, F; Liang, HJ; Mak, SC; Tang, AK; Tang, WK; Ungvari, GS, 2012)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199015 (62.50)18.7374
1990's0 (0.00)18.2507
2000's7 (29.17)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Georgieva, I1
Mulder, CL1
Noorthoorn, E1
Tang, AK1
Tang, WK1
Liang, HJ1
Chan, F1
Mak, SC1
Ungvari, GS1
Huf, G3
Coutinho, ES2
Adams, CE4
HEDQVIST, H1
ERWIN, HJ2
SAMUELS, AS1
SHEA, JG1
SCHULTZ, JD1
LEWIS, E1
FAZEKAS, JF1
SMITH, HW1
WALCHER, W1
LAURENTOVA, J1
BASTECKY, J1
ECKERTOVA, J1
ZAPLATILKOVA, H1
VISSER, SL1
VOJTECHOVSKY, M1
Alexander, J2
Tharyan, P2
Adams, C1
John, T1
Mol, C1
Philip, J1
Jhirwal, OP1
Kulhara, P1
Basu, D1
Raveendran, NS1
da Silva Freire Coutinho, E1
Fagundes, HM1
Oliveira, ES1
Lopez, JR1
Gewandszajder, M1
da Luz Carvalho, A1
Keusen, A1
St Jean, A1
Sterlin, C1
Noe, W1
Ban, TA1
Henkes, HE1
Bienert, H1
Robin, C1
Puech, J1
D'Errico, A1
Morello, G1
Turchiaro, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915]314 participants (Actual)Observational2017-08-01Completed
Rapid Tranquilization of Violent or Agitated People in Psychiatric Emergency Settings- A Pragmatic Randomized Controlled Trial of Intramuscular Olanzepine Vs. Intramuscular Haloperidol + Promethazine.[NCT00455234]Phase 3300 participants Interventional2005-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for promethazine and Mental Disorders

ArticleYear
[CHOLINOTROPIC HALLUCINOGENS. II].
    Lekarska veda v zahranici, 1964, Apr-17, Volume: 35

    Topics: Benactyzine; Hallucinogens; Humans; Lysergic Acid Diethylamide; Mental Disorders; Muscle Relaxants,

1964

Trials

6 trials available for promethazine and Mental Disorders

ArticleYear
Reducing seclusion through involuntary medication: a randomized clinical trial.
    Psychiatry research, 2013, Jan-30, Volume: 205, Issue:1-2

    Topics: Adult; Aggression; Antipsychotic Agents; Coercion; Drug Therapy, Combination; Female; Haloperidol; H

2013
Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine.
    BMJ (Clinical research ed.), 2003, Sep-27, Volume: 327, Issue:7417

    Topics: Adult; Aggression; Drug Therapy, Combination; Emergency Service, Hospital; Emergency Services, Psych

2003
Rapid tranquillisation of violent or agitated patients in a psychiatric emergency setting. Pragmatic randomised trial of intramuscular lorazepam v. haloperidol plus promethazine.
    The British journal of psychiatry : the journal of mental science, 2004, Volume: 185

    Topics: Antipsychotic Agents; Drug Therapy, Combination; Emergencies; Emergency Service, Hospital; Female; H

2004
Rapid tranquillisation in psychiatric emergency settings in India: pragmatic randomised controlled trial of intramuscular olanzapine versus intramuscular haloperidol plus promethazine.
    BMJ (Clinical research ed.), 2007, Oct-27, Volume: 335, Issue:7625

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Drug Combinations; Emergency Services, Psychiatric; Ha

2007
Rapid tranquillisation in psychiatric emergency settings in Brazil: pragmatic randomised controlled trial of intramuscular haloperidol versus intramuscular haloperidol plus promethazine.
    BMJ (Clinical research ed.), 2007, Oct-27, Volume: 335, Issue:7625

    Topics: Adult; Aggression; Antipsychotic Agents; Drug Combinations; Emergency Services, Psychiatric; Haloper

2007
Clinical studies with propericiazine (R.P. 8909).
    Diseases of the nervous system, 1967, Volume: 28, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Association; Behavior; Chlorpromazine; Chronic Disease; Clin

1967

Other Studies

17 other studies available for promethazine and Mental Disorders

ArticleYear
Clinical characteristics of cough mixture abusers referred to three substance abuse clinics in Hong Kong: a retrospective study.
    East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2012, Volume: 22, Issue:4

    Topics: Adult; Antitussive Agents; Azabicyclo Compounds; Codeine; Comorbidity; Diagnosis, Dual (Psychiatry);

2012
TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243].
    BMC psychiatry, 2002, Oct-16, Volume: 2

    Topics: Brazil; Clinical Protocols; Drug Combinations; Emergency Services, Psychiatric; Ethics, Research; Ha

2002
[Phenergan therapy of mental disorder and hyperthymic states].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1952, Volume: 129, Issue:10

    Topics: Anti-Allergic Agents; Emotions; Histamine H1 Antagonists; Mental Disorders; Promethazine; Psychotic

1952
[Experience with promethazine chloride as sedative and hypnotic].
    Svenska lakartidningen, 1954, May-07, Volume: 51, Issue:19

    Topics: Anti-Allergic Agents; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Mental Disorders; P

1954
Clinical observations on the use of promethazine hydrochloride in psychiatric disorders.
    The American journal of psychiatry, 1957, Volume: 113, Issue:9

    Topics: Anti-Allergic Agents; Electroconvulsive Therapy; Histamine H1 Antagonists; Humans; Mental Disorders;

1957
Clinical observations on the use of promethazine hydrochloride in psychiatric disorders.
    The American journal of psychiatry, 1957, Volume: 113, Issue:9

    Topics: Anti-Allergic Agents; Electroconvulsive Therapy; Histamine H1 Antagonists; Humans; Mental Disorders;

1957
Clinical observations on the use of promethazine hydrochloride in psychiatric disorders.
    The American journal of psychiatry, 1957, Volume: 113, Issue:9

    Topics: Anti-Allergic Agents; Electroconvulsive Therapy; Histamine H1 Antagonists; Humans; Mental Disorders;

1957
Clinical observations on the use of promethazine hydrochloride in psychiatric disorders.
    The American journal of psychiatry, 1957, Volume: 113, Issue:9

    Topics: Anti-Allergic Agents; Electroconvulsive Therapy; Histamine H1 Antagonists; Humans; Mental Disorders;

1957
Phenergan in treatment of psychiatric patients.
    Diseases of the nervous system, 1957, Volume: 18, Issue:5

    Topics: Anti-Allergic Agents; Electroconvulsive Therapy; Histamine H1 Antagonists; Mental Disorders; Prometh

1957
The clinical and cerebral action of promethazine and methylphenidate hydrochloride.
    The American journal of the medical sciences, 1958, Volume: 235, Issue:2

    Topics: Counseling; Humans; Medical Records; Mental Disorders; Methylphenidate; Promethazine; Psychoses, Alc

1958
Use of promethazine in alcoholic patients in a state hospital; preliminary report.
    Texas state journal of medicine, 1959, Volume: 55, Issue:3

    Topics: Alcoholism; Electroconvulsive Therapy; Hospitals, State; Humans; Mental Disorders; Promethazine; Psy

1959
[Neurologic-psychiatric problems of extended 1st aid].
    Wiener medizinische Wochenschrift (1946), 1963, Jan-26, Volume: 113

    Topics: Cerebrovascular Disorders; Chlorpromazine; Epilepsy; First Aid; Humans; Mental Disorders; Meperidine

1963
[USE OF REACTIONS TO PSYCHOPHARMACOLOGICAL AGENTS IN THE URINE IN PSYCHIATRIC PRACTICE].
    Activitas nervosa superior, 1963, Volume: 5

    Topics: Chlorpromazine; Guaifenesin; Imipramine; Mental Disorders; Meprobamate; Methotrimeprazine; Perphenaz

1963
[A PARADOXICAL REACTION TO NEUROLEPTICS (EXCITOMOTOR SYNDROME)].
    Nederlands tijdschrift voor geneeskunde, 1963, Nov-30, Volume: 107

    Topics: Alcoholism; Antipsychotic Agents; Bipolar Disorder; Brain Diseases; Chlorpromazine; Electroencephalo

1963
Limitations of rapid tranquillisation trial.
    The British journal of psychiatry : the journal of mental science, 2005, Volume: 187

    Topics: Antipsychotic Agents; Central Nervous System Depressants; Drug Therapy, Combination; Haloperidol; Hu

2005
Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study.
    BMC psychiatry, 2002, Volume: 2

    Topics: Aggression; Benzodiazepines; Brazil; Clinical Protocols; Drug Combinations; Drug Utilization; Emerge

2002
Electro-oculography as a diagnostic aid in phenothiazin retinopathy.
    Transactions of the ophthalmological societies of the United Kingdom, 1967, Volume: 87

    Topics: Adult; Chlorpromazine; Electrooculography; Eye Diseases; Female; Humans; Male; Mental Disorders; Mid

1967
[Promethazine for the prevention and therapy of disturbing side effects in neuro- and thymoleptic drug therapy].
    Die Medizinische Welt, 1967, Apr-15, Volume: 15

    Topics: Female; Humans; Mental Disorders; Promethazine; Schizophrenia

1967
[Sleep therapy. Basic conditions necessary for good results].
    Semaine therapeutique, 1964, Volume: 40, Issue:1

    Topics: Barbiturates; Chlorpromazine; Humans; Mental Disorders; Promethazine; Sleep

1964
[On the use of the chlorpromazine-promethazine- phenobarbital association in psychiatry. Clinical study of 60 cases].
    Minerva medica, 1966, Jan-27, Volume: 57, Issue:8

    Topics: Chlorpromazine; Humans; Mental Disorders; Phenobarbital; Promethazine

1966