promethazine has been researched along with Malaria, Falciparum in 3 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine was the main drug used in treatment of malaria throughout the periods studied, with frequency of prescription at both sites ranging from 91." | 1.35 | Potential contribution of prescription practices to the emergence and spread of chloroquine resistance in south-west Nigeria: caution in the use of artemisinin combination therapy. ( Ganiyu, A; Gbotosho, GO; Happi, CT; Oduola, AM; Ogundahunsi, OA; Sowunmi, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gbotosho, GO | 2 |
| Happi, CT | 2 |
| Ganiyu, A | 1 |
| Ogundahunsi, OA | 2 |
| Sowunmi, A | 3 |
| Oduola, AM | 3 |
| Sijuade, A | 1 |
| Milhous, WK | 1 |
| Brewer, TG | 1 |
| Kyle, DE | 1 |
| Gerena, L | 1 |
| Rossan, RN | 1 |
| Salako, LA | 1 |
| Schuster, BG | 1 |
1 trial available for promethazine and Malaria, Falciparum
| Article | Year |
|---|---|
Comparative study of interactions between chloroquine and chlorpheniramine or promethazine in healthy volunteers: a potential combination-therapy phenomenon for resuscitating chloroquine for malaria treatment in Africa.
Topics: Adult; Animals; Antimalarials; Area Under Curve; Chloroquine; Chlorpheniramine; Chromatography, High | 2008 |
2 other studies available for promethazine and Malaria, Falciparum
| Article | Year |
|---|---|
Potential contribution of prescription practices to the emergence and spread of chloroquine resistance in south-west Nigeria: caution in the use of artemisinin combination therapy.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Hista | 2009 |
In vitro and in vivo reversal of chloroquine resistance in Plasmodium falciparum with promethazine.
Topics: Adult; Animals; Antimalarials; Antipruritics; Aotidae; Aotus trivirgatus; Chloroquine; Disease Model | 1998 |