Page last updated: 2024-11-03

promethazine and Liver Dysfunction

promethazine has been researched along with Liver Dysfunction in 9 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Research Excerpts

ExcerptRelevanceReference
" In retrograde perfusion under low oxygen supply with Ca2+, CCl4 produced essentially the same toxic manifestations as those observed in the anterograde perfusion."1.28Effects of oxygen deficiency and calcium omission on carbon tetrachloride hepatotoxicity in isolated perfused livers from phenobarbital-pretreated rats. ( Masuda, Y; Nakamura, Y, 1990)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
REES, KR1
SPECTOR, WG1
FOX, CF1
DINMAN, BD1
FRAJOLA, WJ1
CARROLL, R1
Masuda, Y1
Nakamura, Y1
Nimmo, J1
Dixon, MF1
Prescott, LF1
Ragnotti, G1
Gaja, G1
Bernelli-Zazzera, A1
Polizzi, M1
Bartoli, GM1
Gaudiano, A1
Montorsi, F1
Petti, G1
Tartarini, S1
Nadeau, D1
Marchand, C1
Rice, AJ1
Plaa, GL1

Other Studies

9 other studies available for promethazine and Liver Dysfunction

ArticleYear
Reversible nature of liver cell damage due to carbon tetrachloride as demonstrated by the use of phenergan.
    Nature, 1961, May-27, Volume: 190

    Topics: Carbon Tetrachloride; Liver; Liver Diseases; Promethazine

1961
CCl4 poisoning II: Serum enzymes, free fatty acids and liver pathology; effects of phenoxybenzamine and phenergan.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1962, Volume: 111

    Topics: Carbon Tetrachloride Poisoning; Fatty Acids, Nonesterified; Liver Diseases; Mitochondria; Oxidoreduc

1962
LESIONS OF THE LIVER PRODUCED BY SUDAN DYES.
    The Journal of pathology and bacteriology, 1964, Volume: 87

    Topics: Chemical and Drug Induced Liver Injury; Coloring Agents; Hepatitis; Liver Diseases; Mice; Pathology;

1964
Effects of oxygen deficiency and calcium omission on carbon tetrachloride hepatotoxicity in isolated perfused livers from phenobarbital-pretreated rats.
    Biochemical pharmacology, 1990, Oct-15, Volume: 40, Issue:8

    Topics: Animals; Calcium; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Li

1990
Effects of mepyramine, promethazine, and hydrocortisone on paracetamol-induced hepatic necrosis in the rat.
    Clinical toxicology, 1973, Volume: 6, Issue:1

    Topics: Acetaminophen; Animals; Benzyl Compounds; Chemical and Drug Induced Liver Injury; Ethylenediamines;

1973
Decline and restoration of glycolysis in homogenates from ischemic livers.
    Experimental and molecular pathology, 1968, Volume: 9, Issue:1

    Topics: Adenine Nucleotides; Animals; Dactinomycin; Fructose-Bisphosphate Aldolase; Glucosyltransferases; Gl

1968
[Effect of some neuroleptic drugs and antihistaminics on the changes of the enzyme pattern induced by ischemia in the rat liver].
    Bollettino della Societa italiana di biologia sperimentale, 1968, May-15, Volume: 44, Issue:9

    Topics: Animals; Cathepsins; Chlorpheniramine; Chlorpromazine; Electron Transport Complex IV; Galactosidases

1968
Importance of the route of administration of ccl 4 in the protective effect of promethazine.
    Biochemical pharmacology, 1973, May-15, Volume: 22, Issue:10

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Glucose-6-Phosp

1973
The role of triglyceride accumulation and of necrosis in the hemodynamic responses of the isolated perfused rat liver after administration of carbon tetrachloride.
    Toxicology and applied pharmacology, 1969, Volume: 14, Issue:1

    Topics: Acetates; Amides; Animals; Body Temperature; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; C

1969