Page last updated: 2024-11-03

promethazine and Inflammation

promethazine has been researched along with Inflammation in 19 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"In order to assess the role of inflammation and its components in spontaneous cure of Strongyloides ratti infestation, rats were treated with non-steroid anti-inflammatory agents (indometacin; sodium salicylate) or with antagonists of certain mediators (dexchlorpheniramin; cyproheptadin, promethazin)."3.67[The role of inflammation in the spontaneous elimination of Strongyloides ratti infestation]. ( Bailenger, J; Lacassie, A, 1986)
"Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects."2.49Topical promethazine side effects: our experience and review of the literature. ( Calvieri, S; Cantisani, C; Faina, V; Grieco, T; Paolino, G; Ricci, S; Silvestri, E, 2013)
"Pretreatment with promethazine, phenylbutazone, methysergide and indomethacin resulted in a decrease in foot oedema."1.27Turpentine-induced acute inflammatory response in Gallus gallus: oedema, vascular permeability and effects of non-steroidal anti-inflammatory drugs. ( Böhm, GM; Ito, NM, 1986)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199016 (84.21)18.7374
1990's0 (0.00)18.2507
2000's1 (5.26)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boia-Ferreira, M1
Moreno, KG1
Basílio, ABC1
da Silva, LP1
Vuitika, L1
Soley, B1
Wille, ACM1
Donatti, L1
Barbaro, KC1
Chaim, OM1
Gremski, LH1
Veiga, SS1
Senff-Ribeiro, A1
Cantisani, C1
Ricci, S1
Grieco, T1
Paolino, G1
Faina, V1
Silvestri, E1
Calvieri, S1
BEDELL, RH1
BULLE, PH1
O'ROURKE, J1
NATHAN, AS1
RUBIN, BJ1
ROSEN, MB1
LASKIN, DM1
KOLODNY, SC1
JANOFF, A1
ZWEIFACH, BW1
BRANCENI, D1
AZADIAN-BOULANGER, G1
JEQUIER, R1
Craig, A1
Pfeffer, WH1
Wheeler, JE1
Tschoepe, RL1
Wright, KH1
Gizang, E1
Kuriyama, K1
Hiyama, Y1
Nagatahira, R1
Okuda, T1
Saito, K1
Ito, K1
Neil, A1
Benoist, JM1
Kayser, V1
Guilbaud, G1
Bailenger, J1
Lacassie, A1
Ito, NM1
Böhm, GM1
Altura, BM1
Altura, BT1
Farkas, K1
Lörincz, G1
Feldbush, TL1
Hichens, M1
Parr, E1
Ryan, GB1
Hurley, JV1
Wilhelmi, G1
Gdynia, R1

Reviews

2 reviews available for promethazine and Inflammation

ArticleYear
Topical promethazine side effects: our experience and review of the literature.
    BioMed research international, 2013, Volume: 2013

    Topics: Epidermis; Histamine H1 Antagonists; Humans; Inflammation; Promethazine; Skin Diseases

2013
Effects of local anesthetics, antihistamines, and glucocorticoids on peripheral blood flow and vascular smooth muscle.
    Anesthesiology, 1974, Volume: 41, Issue:2

    Topics: Anesthetics, Local; Animals; Blood Vessels; Cats; Diphenhydramine; Dogs; Glucocorticoids; Histamine;

1974

Other Studies

17 other studies available for promethazine and Inflammation

ArticleYear
TCTP from
    Cells, 2019, 11-22, Volume: 8, Issue:12

    Topics: Animals; Biomarkers, Tumor; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Drug; Hypersens

2019
TRIIODOTHYRONINE, HYPERTHERMIA, AND CORTICOSTEROID INFLUENCE ON ISOLATED IRIS TISSUE RESPIRATION.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1963, Volume: 70

    Topics: Adrenal Cortex Hormones; Animals; Aqueous Humor; Dexamethasone; Fever; Inflammation; Iris; Liver; Me

1963
CONSERVATIVE TREATMENT OF A LARGE RADICULAR CYST OF THE MANDIBLE IN A PATIENT WITH SEVERE HEMOPHILIA. REPORT OF A CASE.
    Oral surgery, oral medicine, and oral pathology, 1964, Volume: 17

    Topics: Aspirin; Blood Chemical Analysis; Blood Transfusion; Dentigerous Cyst; Diagnosis, Differential; Drai

1964
INHIBITION OF EXUDATE PRODUCTION BY ANTI-INFLAMMATORY DRUGS.
    Journal of oral therapeutics and pharmacology, 1965, Volume: 1

    Topics: Anti-Inflammatory Agents; Chlorpheniramine; Chlorpromazine; Deoxyribonuclease I; Exudates and Transu

1965
PRODUCTION OF INFLAMMATORY CHANGES IN THE MICROCIRCULATION BY CATIONIC PROTEINS EXTRACTED FROM LYSOSOMES.
    The Journal of experimental medicine, 1964, Nov-01, Volume: 120

    Topics: Acid Phosphatase; Animals; Bradykinin; Capillary Permeability; Cytoplasmic Granules; Exudates and Tr

1964
[EXPERIMENTAL INFLAMMATION INDUCED BY A HEPARIN ANALOG. A TEST OF ANTI-INFLAMMATORY ACTIVITY].
    Archives internationales de pharmacodynamie et de therapie, 1964, Nov-01, Volume: 152

    Topics: Amodiaquine; Anti-Allergic Agents; Anti-Inflammatory Agents; Aspirin; Chemistry, Pharmaceutical; Col

1964
Pain, inflammation and a nodule after IV medication.
    Advance for nurse practitioners, 2005, Volume: 13, Issue:7

    Topics: Adult; Female; Forearm; Gastroenteritis; Histamine H1 Antagonists; Humans; Inflammation; Injections,

2005
The effect of dexamethasone and promethazine administration on adhesion formation, tubal function, and ultrastructure following microsurgical anastomosis of rabbit oviducts.
    Fertility and sterility, 1980, Volume: 34, Issue:2

    Topics: Animals; Collagen; Dexamethasone; Embryo Implantation; Fallopian Tube Patency Tests; Fallopian Tubes

1980
An antiallergic activity of disodium cromoglycate unrelated to mast cell activation.
    Agents and actions, 1986, Volume: 18, Issue:5-6

    Topics: Allergens; Animals; Carrageenan; Cromolyn Sodium; Histamine H1 Antagonists; Histamine Release; Hyper

1986
Initial nociceptive sensitization in carrageenin-induced rat paw inflammation is dependent on amine autacoid mechanisms: electrophysiological and behavioural evidence obtained with a quaternary antihistamine, thiazinamium.
    Experimental brain research, 1987, Volume: 65, Issue:2

    Topics: Animals; Behavior, Animal; Carrageenan; Inflammation; Injections, Subcutaneous; Male; Nociceptors; P

1987
[The role of inflammation in the spontaneous elimination of Strongyloides ratti infestation].
    Annales de parasitologie humaine et comparee, 1986, Volume: 61, Issue:6

    Topics: Animals; Chlorpheniramine; Cyproheptadine; Indomethacin; Inflammation; Male; Nematode Infections; Pr

1986
Turpentine-induced acute inflammatory response in Gallus gallus: oedema, vascular permeability and effects of non-steroidal anti-inflammatory drugs.
    Research in veterinary science, 1986, Volume: 41, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Chickens; Edema; Indometha

1986
Arthritis of rats inoculated with granuloma pouch exudate.
    Acta rheumatologica Scandinavica, 1967, Volume: 13, Issue:3

    Topics: Animals; Ankle Joint; Arthritis; Bone Marrow Diseases; Exudates and Transudates; Female; Granulation

1967
An acute allergic inflammation in the rat.
    The Journal of pathology, 1970, Volume: 101, Issue:2

    Topics: Animals; Antibodies; Antibody Formation; Diethylcarbamazine; Freund's Adjuvant; Hindlimb; Histamine

1970
The role of uterine inflammation in the inhibition of decidualization by intraluminal antihistamines.
    Biology of reproduction, 1969, Volume: 1, Issue:3

    Topics: Animals; Decidua; Dibenzylchlorethamine; Diphenhydramine; Endometrium; Female; Histamine H1 Antagoni

1969
The drug inhibition of increased vascular permeability.
    The Journal of pathology and bacteriology, 1968, Volume: 96, Issue:2

    Topics: Animals; Blood Vessels; Burns; Capillary Permeability; Chlorpromazine; Digoxin; Diphenhydramine; Ind

1968
[On the phlogogenic properties of lactic acid in animal experiments].
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:12

    Topics: Animals; Capillary Permeability; Conjunctivitis; Edema; Exudates and Transudates; Guinea Pigs; Infla

1968