Page last updated: 2024-11-03

promethazine and Huntington Disease

promethazine has been researched along with Huntington Disease in 1 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cleren, C1
Calingasan, NY1
Starkov, A1
Jacquard, C1
Chen, J1
Brouillet, E1
Beal, MF1

Other Studies

1 other study available for promethazine and Huntington Disease

ArticleYear
Promethazine protects against 3-nitropropionic acid-induced neurotoxicity.
    Neurochemistry international, 2010, Volume: 56, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Brain Ischemia; Disease Models, Animal; Huntington Disease;

2010