promethazine has been researched along with Granulocytic Leukemia, Chronic in 1 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Philadelphia positive chronic myeloid leukemia (CML) K562 cells were the most sensitive cell line." | 1.56 | AMPK activation induced by promethazine increases NOXA expression and Beclin-1 phosphorylation and drives autophagy-associated apoptosis in chronic myeloid leukemia. ( Colturato-Kido, C; Costa, CA; Ferraz, LS; Medeiros, HCD; Moraes, VWR; Paredes-Gamero, EJ; Rodrigues, T; Tersariol, ILS, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Medeiros, HCD | 1 |
| Colturato-Kido, C | 1 |
| Ferraz, LS | 1 |
| Costa, CA | 1 |
| Moraes, VWR | 1 |
| Paredes-Gamero, EJ | 1 |
| Tersariol, ILS | 1 |
| Rodrigues, T | 1 |
1 other study available for promethazine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
AMPK activation induced by promethazine increases NOXA expression and Beclin-1 phosphorylation and drives autophagy-associated apoptosis in chronic myeloid leukemia.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Autophagy; Beclin-1; Cell Line, Tum | 2020 |