Page last updated: 2024-11-03

promethazine and Drug Overdose

promethazine has been researched along with Drug Overdose in 14 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to describe the clinical effects of promethazine in overdose and explore the relationship between delirium and possible predictor variables."7.75Promethazine overdose: clinical effects, predicting delirium and the effect of charcoal. ( Duffull, SB; Isbister, GK; Page, CB; Whyte, IM, 2009)
"The aim of this study was to describe the clinical effects of promethazine in overdose and explore the relationship between delirium and possible predictor variables."3.75Promethazine overdose: clinical effects, predicting delirium and the effect of charcoal. ( Duffull, SB; Isbister, GK; Page, CB; Whyte, IM, 2009)
"Promethazine is a phenothiazine derivative antihistamine first introduced in the 1940s that is used in multiple medical conditions as a sedative/hypnotic agent."2.58[Promethazine - an old pharmaceutical that has got a renaissance. An avalanche-like increase in the number of overdose cases in Sweden]. ( Höjer, J; Tellerup, M, 2018)
"We report a case of iatrogenic cardiac arrest in a 2-month-old infant in whom a consulting resident administered too much MPC (10 times the expected dose) by the wrong route (intravenous instead of intramuscular)."1.31Iatrogenic cardiopulmonary arrest during pediatric sedation with meperidine, promethazine, and chlorpromazine. ( Brown, ET; Corbett, SW; Green, SM, 2001)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (35.71)18.2507
2000's4 (28.57)29.6817
2010's4 (28.57)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Thunander Sundbom, L1
Fornstedt Wallin, B1
Wändel Liminga, U1
Nordmark Grass, J1
K Jönsson, A1
Nurminen, ML1
Höjer, J1
Tellerup, M1
Jensen, LL1
Rømsing, J1
Dalhoff, K1
Page, CB1
Duffull, SB1
Whyte, IM1
Isbister, GK1
Petik, D1
Czeizel, B1
Banhidy, F1
Czeizel, AE1
Sanklecha, M1
Charde, V1
Daldrup, T1
Scott, J1
Pache, D1
Keane, G1
Buckle, H1
O'Brien, N1
Staley, EC1
Staley, EE1
Perera, I1
Williams, KR1
Pounder, DJ1
Bergman, J1
Wallman, P1
Moriya, F1
Hashimoto, Y1
Brown, ET1
Corbett, SW1
Green, SM1

Reviews

1 review available for promethazine and Drug Overdose

ArticleYear
[Promethazine - an old pharmaceutical that has got a renaissance. An avalanche-like increase in the number of overdose cases in Sweden].
    Lakartidningen, 2018, 07-24, Volume: 115

    Topics: Antidotes; Drug Overdose; Drug Utilization; Female; Humans; Middle Aged; Physostigmine; Poison Contr

2018

Other Studies

13 other studies available for promethazine and Drug Overdose

ArticleYear
[Sedating antihistamines - risk of severe intoxication].
    Lakartidningen, 2021, 09-30, Volume: 118

    Topics: Cholinergic Antagonists; Drug Overdose; Histamine H1 Antagonists; Humans; Promethazine; Sweden

2021
A Danish Survey of Antihistamine Use and Poisoning Patterns.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 120, Issue:1

    Topics: Age Factors; Denmark; Drug Monitoring; Drug Overdose; Drug Therapy, Combination; Female; Health Care

2017
Promethazine overdose: clinical effects, predicting delirium and the effect of charcoal.
    QJM : monthly journal of the Association of Physicians, 2009, Volume: 102, Issue:2

    Topics: Adolescent; Adult; Antidotes; Charcoal; Delirium; Dose-Response Relationship, Drug; Drug Overdose; F

2009
A study of the risk of mental retardation among children of pregnant women who have attempted suicide by means of a drug overdose.
    Journal of injury & violence research, 2012, Volume: 4, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Amobarbital; Birth Weight; Chi-Square Distribution; Drug Combina

2012
Domperidone disaster: need for a single formulation?
    Indian journal of pediatrics, 2013, Volume: 80, Issue:7

    Topics: Antiemetics; Blood Chemical Analysis; Domperidone; Drug Overdose; Electrocardiography; Histamine H1

2013
A forensic toxicological dilemma: the interpretation of post-mortem concentrations of central acting analgesics.
    Forensic science international, 2004, Jun-10, Volume: 142, Issue:2-3

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Brain Chemistry; Diagnostic Errors; Drug Overdose; Fema

2004
Prolonged anticholinergic delirium following antihistamine overdose.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2007, Volume: 15, Issue:3

    Topics: Adolescent; Cholinergic Antagonists; Cyproheptadine; Cytochrome P-450 CYP2D6 Inhibitors; Delirium; D

2007
Promethazine toxicity in a seven-month-old Doberman pinscher.
    Veterinary and human toxicology, 1995, Volume: 37, Issue:3

    Topics: Administration, Rectal; Animals; Antiemetics; Dog Diseases; Dogs; Drug Overdose; Female; Lymphadenit

1995
What you need to know: addiction--cough mixture.
    Singapore medical journal, 1997, Volume: 38, Issue:3

    Topics: Acute Disease; Adrenergic alpha-Agonists; Antitussive Agents; Chronic Disease; Clonidine; Codeine; D

1997
Site-to-site variability of drug concentrations in skeletal muscle.
    The American journal of forensic medicine and pathology, 1997, Volume: 18, Issue:3

    Topics: Acetaminophen; Central Nervous System Agents; Dibenzocycloheptenes; Dothiepin; Drug Overdose; Gas Ch

1997
Promethazine overdose: is it a "Goodnight" after all?
    The New Zealand medical journal, 1998, Jul-10, Volume: 111, Issue:1069

    Topics: Adolescent; Adult; Advertising; Drug Industry; Drug Overdose; Emergency Service, Hospital; Female; H

1998
Redistribution of basic drugs into cardiac blood from surrounding tissues during early-stages postmortem.
    Journal of forensic sciences, 1999, Volume: 44, Issue:1

    Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Autopsy; Central Nervous System Sti

1999
Iatrogenic cardiopulmonary arrest during pediatric sedation with meperidine, promethazine, and chlorpromazine.
    Pediatric emergency care, 2001, Volume: 17, Issue:5

    Topics: Chlorpromazine; Conscious Sedation; Drug Combinations; Drug Overdose; Emergency Service, Hospital; H

2001