promethazine has been researched along with Disorders of Excessive Somnolence in 2 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Excessive daytime sleepiness, which had occurred in the cases as an H1-antihistamine-induced ADR, was assessed by the Epworth sleepiness scale (ESS), and an ESS score >or=12 was considered hypersomnia." | 1.33 | Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia. ( Ikeda, K; Kamataki, T; Marubayashi, T; Matsunaga, M; Mihara, S; Nakagawa, K; Nakao, M; Oniki, K; Saruwatari, J; Seo, T, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fiedler, J | 1 |
| Feiveson, AH | 1 |
| Hayat, MJ | 1 |
| Vaksman, Z | 1 |
| Boyd, JL | 1 |
| Putcha, L | 1 |
| Saruwatari, J | 1 |
| Matsunaga, M | 1 |
| Ikeda, K | 1 |
| Nakao, M | 1 |
| Oniki, K | 1 |
| Seo, T | 1 |
| Mihara, S | 1 |
| Marubayashi, T | 1 |
| Kamataki, T | 1 |
| Nakagawa, K | 1 |
2 other studies available for promethazine and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Joint modeling of performance and subjective reporting to assess sensitivity to drug-induced sleepiness.
Topics: Algorithms; Bayes Theorem; Cognition; Cross-Over Studies; Diagnostic Self Evaluation; Disorders of E | 2010 |
Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia.
Topics: Asian People; Chlorpheniramine; Clemastine; Cytochrome P-450 CYP2D6; Disorders of Excessive Somnolen | 2006 |