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promethazine and Disorders of Excessive Somnolence

promethazine has been researched along with Disorders of Excessive Somnolence in 2 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)

Research Excerpts

ExcerptRelevanceReference
"Excessive daytime sleepiness, which had occurred in the cases as an H1-antihistamine-induced ADR, was assessed by the Epworth sleepiness scale (ESS), and an ESS score >or=12 was considered hypersomnia."1.33Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia. ( Ikeda, K; Kamataki, T; Marubayashi, T; Matsunaga, M; Mihara, S; Nakagawa, K; Nakao, M; Oniki, K; Saruwatari, J; Seo, T, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fiedler, J1
Feiveson, AH1
Hayat, MJ1
Vaksman, Z1
Boyd, JL1
Putcha, L1
Saruwatari, J1
Matsunaga, M1
Ikeda, K1
Nakao, M1
Oniki, K1
Seo, T1
Mihara, S1
Marubayashi, T1
Kamataki, T1
Nakagawa, K1

Other Studies

2 other studies available for promethazine and Disorders of Excessive Somnolence

ArticleYear
Joint modeling of performance and subjective reporting to assess sensitivity to drug-induced sleepiness.
    Statistics in medicine, 2010, Sep-20, Volume: 29, Issue:21

    Topics: Algorithms; Bayes Theorem; Cognition; Cross-Over Studies; Diagnostic Self Evaluation; Disorders of E

2010
Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:12

    Topics: Asian People; Chlorpheniramine; Clemastine; Cytochrome P-450 CYP2D6; Disorders of Excessive Somnolen

2006