Page last updated: 2024-11-03

promethazine and Delirium

promethazine has been researched along with Delirium in 9 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Delirium: A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)

Research Excerpts

ExcerptRelevanceReference
"There is limited information about promethazine-induced delirium with psychotic symptoms."8.02Promethazine-induced delirium with perceptual abnormalities: are we thinking broadly when assessing patients? ( Abeysundera, H; Craig, B; Pullich, Z, 2021)
"The aim of this study was to describe the clinical effects of promethazine in overdose and explore the relationship between delirium and possible predictor variables."7.75Promethazine overdose: clinical effects, predicting delirium and the effect of charcoal. ( Duffull, SB; Isbister, GK; Page, CB; Whyte, IM, 2009)
"Promethazine was prescribed, and this was the patient's only medication on admission."5.30Neuroleptic malignant syndrome due to promethazine. ( Chan-Tack, KM, 1999)
"There is limited information about promethazine-induced delirium with psychotic symptoms."4.02Promethazine-induced delirium with perceptual abnormalities: are we thinking broadly when assessing patients? ( Abeysundera, H; Craig, B; Pullich, Z, 2021)
"The aim of this study was to describe the clinical effects of promethazine in overdose and explore the relationship between delirium and possible predictor variables."3.75Promethazine overdose: clinical effects, predicting delirium and the effect of charcoal. ( Duffull, SB; Isbister, GK; Page, CB; Whyte, IM, 2009)
"Five cases of post narcotic delirium, somnolence or coma are interpreted as central anticholinergic syndromes as they were reversed by physostigmine."3.66[Physostigmine reversal of central anticholinergic syndrome induced by midazolam/fentanyl, benzoctamine/buprenorphine and etomidate/carticaine or by atropine/promethazine/pethidine for premedication? (author's transl)]. ( Jost, U; Ruppert, M; Schmid, A, 1982)
"Promethazine was prescribed, and this was the patient's only medication on admission."1.30Neuroleptic malignant syndrome due to promethazine. ( Chan-Tack, KM, 1999)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Abeysundera, H1
Craig, B1
Pullich, Z1
Page, CB1
Duffull, SB1
Whyte, IM1
Isbister, GK1
Scott, J1
Pache, D1
Keane, G1
Buckle, H1
O'Brien, N1
Werner, V1
Diehl, LW1
Jost, U1
Schmid, A1
Ruppert, M1
Chan-Tack, KM1
Isaac, M2
Pandit, SK2
Dundee, JW2
Galway, JE1
McDowell, SA1
Besada Varela, L1

Reviews

1 review available for promethazine and Delirium

ArticleYear
[The state of psychopharmacotherapy in geriatrics 2].
    Therapie der Gegenwart, 1980, Volume: 119, Issue:12

    Topics: Actihaemyl; Aged; Amitriptyline; Bencyclane; Cerebrovascular Circulation; Clorazepate Dipotassium; D

1980

Other Studies

8 other studies available for promethazine and Delirium

ArticleYear
Promethazine-induced delirium with perceptual abnormalities: are we thinking broadly when assessing patients?
    BMJ case reports, 2021, Apr-15, Volume: 14, Issue:4

    Topics: Delirium; Humans; Nonprescription Drugs; Promethazine; Substance-Related Disorders

2021
Promethazine overdose: clinical effects, predicting delirium and the effect of charcoal.
    QJM : monthly journal of the Association of Physicians, 2009, Volume: 102, Issue:2

    Topics: Adolescent; Adult; Antidotes; Charcoal; Delirium; Dose-Response Relationship, Drug; Drug Overdose; F

2009
Prolonged anticholinergic delirium following antihistamine overdose.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2007, Volume: 15, Issue:3

    Topics: Adolescent; Cholinergic Antagonists; Cyproheptadine; Cytochrome P-450 CYP2D6 Inhibitors; Delirium; D

2007
[Physostigmine reversal of central anticholinergic syndrome induced by midazolam/fentanyl, benzoctamine/buprenorphine and etomidate/carticaine or by atropine/promethazine/pethidine for premedication? (author's transl)].
    Der Anaesthesist, 1982, Volume: 31, Issue:1

    Topics: Adult; Aged; Anthracenes; Atropine; Benzodiazepines; Buprenorphine; Carticaine; Coma; Delirium; Etom

1982
Neuroleptic malignant syndrome due to promethazine.
    Southern medical journal, 1999, Volume: 92, Issue:10

    Topics: Acidosis; Adult; Antiemetics; Arrhythmia, Sinus; Creatine Kinase; Delirium; Fever; Humans; Hypernatr

1999
Intravenous ethanol anaesthesia. A study of sequelae and their implications.
    Acta anaesthesiologica Scandinavica, 1971, Volume: 15, Issue:3

    Topics: Alcohol Deterrents; Alcoholic Intoxication; Amnesia; Anesthesia, Intravenous; Atropine; Barbiturates

1971
Clinical studies of induction agents. XXXIV: Further investigations with ethanol.
    British journal of anaesthesia, 1970, Volume: 42, Issue:4

    Topics: Anesthesia, Intravenous; Atropine; Barbiturates; Chlordiazepoxide; Delirium; Drug Antagonism; Ethano

1970
[Clinical experiences with T.P.N. 12 in schizophrenic deliria].
    Actas luso-espanolas de neurologia y psiquiatria, 1967, Volume: 26, Issue:2

    Topics: Adult; Delirium; Female; Humans; Male; Middle Aged; Promethazine; Schizophrenia; Thioridazine

1967