Page last updated: 2024-11-03

promethazine and Cough

promethazine has been researched along with Cough in 15 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"To evaluate whether promethazine and dextromethorphan reduce nocturnal cough and improve sleep quality in children aged 1-12 y with upper respiratory tract infection (URI)."9.17To compare the effect of dextromethorphan, promethazine and placebo on nocturnal cough in children aged 1-12 y with upper respiratory infections: a randomized controlled trial. ( Bhattacharya, M; Joshi, N; Yadav, S, 2013)
"A mixture of codeine cough syrup with alcohol and/or a soft drink known as "purple drank" has gained media attention in recent years as a drug associated with professional athletes and southern rap music."7.79Purple drank prevalence and characteristics of misusers of codeine cough syrup mixtures. ( Agnich, LE; Marcum, CD; Miller, BL; Stogner, JM, 2013)
"In this study a qualitative approach is used to investigate relevant beliefs and norms concerning the consumption, initiation, and perceived addiction of codeine and promethazine hydrochloride cough syrup (CPHCS) among 61 college-age students who identified themselves as current CPHCS users."7.74Beliefs and social norms about codeine and promethazine hydrochloride cough syrup (CPHCS) use and addiction among multi-ethnic college students. ( Bowers, KS; Essien, EJ; Eulian, VM; Forsythe, KJ; Mangum, CA; Martin, Q; O'Neal, JD; Peters, R; Rhodes, W; Yacoubian, GS, 2007)
"In the current study, we used a qualitative approach to investigate relevant beliefs and norms associated with codeine and promethazine hydrochloride cough syrup (CPHCS) consumption, initiation, and perceived addiction among 48 alternative school students who identified themselves as current CPHCS users."7.72Beliefs and social norms about codeine and promethazine hydrochloride cough syrup (CPHCS) onset and perceived addiction among urban Houstonian adolescents: an addiction trend in the city of lean. ( Ellis, A; Kelder, SH; Markham, CM; Peters, LA; Peters, RJ; Yacoubian, GS, 2003)
"To evaluate whether promethazine and dextromethorphan reduce nocturnal cough and improve sleep quality in children aged 1-12 y with upper respiratory tract infection (URI)."5.17To compare the effect of dextromethorphan, promethazine and placebo on nocturnal cough in children aged 1-12 y with upper respiratory infections: a randomized controlled trial. ( Bhattacharya, M; Joshi, N; Yadav, S, 2013)
"A mixture of codeine cough syrup with alcohol and/or a soft drink known as "purple drank" has gained media attention in recent years as a drug associated with professional athletes and southern rap music."3.79Purple drank prevalence and characteristics of misusers of codeine cough syrup mixtures. ( Agnich, LE; Marcum, CD; Miller, BL; Stogner, JM, 2013)
"In this study a qualitative approach is used to investigate relevant beliefs and norms concerning the consumption, initiation, and perceived addiction of codeine and promethazine hydrochloride cough syrup (CPHCS) among 61 college-age students who identified themselves as current CPHCS users."3.74Beliefs and social norms about codeine and promethazine hydrochloride cough syrup (CPHCS) use and addiction among multi-ethnic college students. ( Bowers, KS; Essien, EJ; Eulian, VM; Forsythe, KJ; Mangum, CA; Martin, Q; O'Neal, JD; Peters, R; Rhodes, W; Yacoubian, GS, 2007)
"In the current study, we used a qualitative approach to investigate relevant beliefs and norms associated with codeine and promethazine hydrochloride cough syrup (CPHCS) consumption, initiation, and perceived addiction among 48 alternative school students who identified themselves as current CPHCS users."3.72Beliefs and social norms about codeine and promethazine hydrochloride cough syrup (CPHCS) onset and perceived addiction among urban Houstonian adolescents: an addiction trend in the city of lean. ( Ellis, A; Kelder, SH; Markham, CM; Peters, LA; Peters, RJ; Yacoubian, GS, 2003)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhattacharya, M1
Joshi, N1
Yadav, S1
Agnich, LE1
Stogner, JM1
Miller, BL1
Marcum, CD1
Kigen, G1
Busakhala, N1
Ogaro, F1
Chesire, E1
Saat, N1
Too, R1
Nyandiko, W1
PHILLIPS, FJ1
CHAI, CL1
SHOEMAKER, DM1
SALEM, H1
AVIADO, DM1
Peters, RJ1
Kelder, SH1
Markham, CM1
Yacoubian, GS2
Peters, LA1
Ellis, A1
Peters, R1
Rhodes, W1
Forsythe, KJ1
Bowers, KS1
Eulian, VM1
Mangum, CA1
O'Neal, JD1
Martin, Q1
Essien, EJ1
Böhlau, V1
Schildwächter, G1
Jancik, EH1
van der Weele, LT1
Orie, NG1
Manresa, F1
Kessell, J1
Fontaine, G1
Farriaux, JP1
Delilkan, AE1
Chandran, S1
Bartsch, R1
Dundee, JW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Oral Procaterol on Chronic Persistent Cough Following Upper Respiratory Tract Infection: Double-Blind Randomized Placebo-Controlled Trial[NCT02349919]74 participants (Anticipated)Interventional2015-03-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for promethazine and Cough

ArticleYear
ANTITUSSIVE DRUGS, WITH SPECIAL REFERENCE TO A NEW THEORY FOR THE INITATION OF THE COUGH REFLEX AND THE INFLUENCE OR BRONCHODILATORS.
    The American journal of the medical sciences, 1964, Volume: 247

    Topics: Acetaminophen; Aerosols; Aminophylline; Analgesics; Analgesics, Non-Narcotic; Animals; Antimony; Ant

1964
Atropine premedication.
    Anaesthesia and intensive care, 1974, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Clinical Trials as Top

1974

Trials

5 trials available for promethazine and Cough

ArticleYear
To compare the effect of dextromethorphan, promethazine and placebo on nocturnal cough in children aged 1-12 y with upper respiratory infections: a randomized controlled trial.
    Indian journal of pediatrics, 2013, Volume: 80, Issue:11

    Topics: Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Double-Blind Method; Female; H

2013
[Therpeutic experiences with a new antitussive principle].
    Fortschritte der Medizin, 1976, Dec-02, Volume: 94, Issue:34

    Topics: Adult; Antitussive Agents; Codeine; Constipation; Cough; Diarrhea; Drug Combinations; Fatigue; Femal

1976
The occurrence of symptoms of possibly chronic airway diseases in toddlers. A three-year follow-up study and a double-blind trial to establish the influence of an anti-allergic maintainance medication.
    Pneumonologie. Pneumonology, 1975, May-30, Volume: 151, Issue:4

    Topics: Age Factors; Chronic Disease; Clinical Trials as Topic; Cough; Follow-Up Studies; Humans; Infant; Lu

1975
Atropine premedication.
    Anaesthesia and intensive care, 1974, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Clinical Trials as Top

1974
Cataract extractions without tracheal intubation.
    Canadian Anaesthetists' Society journal, 1974, Volume: 21, Issue:4

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Atropine; Carbon Dioxide; Cataract Ext

1974

Other Studies

9 other studies available for promethazine and Cough

ArticleYear
Purple drank prevalence and characteristics of misusers of codeine cough syrup mixtures.
    Addictive behaviors, 2013, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Antitussive Agents; Asian; Black or African American; Codeine; Cough; Data Collec

2013
A Review of the Ingredients Contained in Over the Counter (OTC) Cough Syrup Formulations in Kenya. Are They Harmful to Infants?
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Antitussive Agents; Child, Preschool; Cough; Cross-Sectional Studies; Expectorants; Female; Histamin

2015
Experience with a new cough preparation: report of 203 cases.
    Current therapeutic research, clinical and experimental, 1963, Volume: 5

    Topics: Antitussive Agents; Codeine; Cough; Humans; Phenylephrine; Promethazine

1963
Beliefs and social norms about codeine and promethazine hydrochloride cough syrup (CPHCS) onset and perceived addiction among urban Houstonian adolescents: an addiction trend in the city of lean.
    Journal of drug education, 2003, Volume: 33, Issue:4

    Topics: Adolescent; Antitussive Agents; Codeine; Cough; Female; Humans; Male; Promethazine; Public Opinion;

2003
Beliefs and social norms about codeine and promethazine hydrochloride cough syrup (CPHCS) use and addiction among multi-ethnic college students.
    Journal of psychoactive drugs, 2007, Volume: 39, Issue:3

    Topics: Antitussive Agents; Black People; Codeine; Cough; Drug Combinations; Female; Humans; Male; Promethaz

2007
Should symptoms--namely cough and dyspnoea--be treated?
    European journal of respiratory diseases. Supplement, 1986, Volume: 146

    Topics: Codeine; Cough; Diazepam; Dyspnea; Ethanol; Humans; Oxygen Inhalation Therapy; Promethazine; Theophy

1986
[Clinical trial of a new antitussive agent, Teletux, in children].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1972, Volume: 17

    Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Delayed-Action Preparations; Female;

1972
[Study of antitussive effect of 9,9-dioxopromethazine (Prothanon)].
    Die Pharmazie, 1970, Feb-02, Volume: 25, Issue:2

    Topics: Animals; Antitussive Agents; Citrates; Codeine; Cough; Depression, Chemical; Electric Stimulation; E

1970
Ultrashort-acting barbiturates for out-patients.
    Acta anaesthesiologica Scandinavica. Supplementum, 1965, Volume: 17

    Topics: Anesthesia, Intravenous; Atropine; Barbiturates; Blood Pressure; Cough; Hiccup; Humans; Methohexital

1965