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promethazine and Arrhythmias, Cardiac

promethazine has been researched along with Arrhythmias, Cardiac in 15 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"The effects of the H1-receptor antagonists promethazine, mepyramine, and chlorpheniramine on ischemic and reperfusion arrhythmias were studied in the isolated perfused rat heart."7.67Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart. ( Bralet, J; Opie, LH; Rochette, L; Yao-Kouame, J, 1988)
"Ouabain-induced tachyarrhythmias in cats can be abolished by bolus injection of NaHCO3 solution."7.65Antiarrhythmic effect of hypertonic sodium bicarbonate and sodium chloride in ouabain-induced arrhythmias. ( Aryanpur, I; Paydar, M; Reyhani, F; Shakibi, JG; Siassi, B, 1976)
"The effects of the H1-receptor antagonists promethazine, mepyramine, and chlorpheniramine on ischemic and reperfusion arrhythmias were studied in the isolated perfused rat heart."3.67Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart. ( Bralet, J; Opie, LH; Rochette, L; Yao-Kouame, J, 1988)
"Ouabain-induced tachyarrhythmias in cats can be abolished by bolus injection of NaHCO3 solution."3.65Antiarrhythmic effect of hypertonic sodium bicarbonate and sodium chloride in ouabain-induced arrhythmias. ( Aryanpur, I; Paydar, M; Reyhani, F; Shakibi, JG; Siassi, B, 1976)
"Pretreatment with promethazine and cimetidine, as H1 and H2 histamine receptor antagonists, markedly prevented the development of phase II, namely the rise in cardiac frequency, LVPs, MAP and TPR, but did not significantly modify phase I and III."1.27The pattern of cardiovascular alterations induced by infusion of platelet-activating factor in rabbit is modified by pretreatment with H1-H2 receptor antagonists but not by cyclooxygenase inhibition. ( Alloatti, G; Camussi, G; Emanuelli, G; Mariano, F; Meda, E; Montrucchio, G; Tetta, C, 1987)
" The adverse effects of MPC were studied prospectively in 95 patients undergoing various procedures."1.27Adverse effects of meperidine, promethazine, and chlorpromazine for sedation in pediatric patients. ( Clotz, MA; Krogg, EA; Nahata, MC, 1985)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199014 (93.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
La Gamba, F1
Corrao, G1
Romio, S1
Sturkenboom, M1
Trifirò, G1
Schink, T1
de Ridder, M1
BEAULNES, A1
LAVALLEE, M1
Somberg, JC1
Bounous, H1
Cagin, N1
Levitt, B1
Levi, R1
Capurro, N1
Lee, CH1
Gyermek, L1
Shakibi, JG1
Aryanpur, I1
Paydar, M1
Reyhani, F1
Siassi, B1
Rochette, L1
Yao-Kouame, J1
Bralet, J1
Opie, LH1
Montrucchio, G1
Alloatti, G1
Mariano, F1
Meda, E1
Tetta, C1
Emanuelli, G1
Camussi, G1
Nahata, MC1
Clotz, MA1
Krogg, EA1
Gupta, SC1
Sharma, VN1
Sharma, HL1
Kessell, J1
Shamsi, MA1
Kulshrestha, VK1
Dhawan, KN1
Bhargava, KP1
Bingham, W1
Elliott, J1
Lyons, SM1
Baum, T1
Eckfeld, DK1
Shropshire, AT1
Rowles, G1
Varner, LL1
Weisman, H1

Reviews

1 review available for promethazine and Arrhythmias, Cardiac

ArticleYear
Atropine premedication.
    Anaesthesia and intensive care, 1974, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Clinical Trials as Top

1974

Trials

1 trial available for promethazine and Arrhythmias, Cardiac

ArticleYear
Atropine premedication.
    Anaesthesia and intensive care, 1974, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Clinical Trials as Top

1974

Other Studies

14 other studies available for promethazine and Arrhythmias, Cardiac

ArticleYear
Combining evidence from multiple electronic health care databases: performances of one-stage and two-stage meta-analysis in matched case-control studies.
    Pharmacoepidemiology and drug safety, 2017, Volume: 26, Issue:10

    Topics: Arrhythmias, Cardiac; Bias; Cluster Analysis; Databases, Factual; Delivery of Health Care; Humans; M

2017
DIFFERENTIAL EFFECTS OF SOME PHENOTHIAZINE DERIVATIVES AGAINST CALCIUM-INDUCED VENTRICULAR ARRHYTHMIAS IN THE ISOLATED RABBIT HEART.
    Canadian journal of physiology and pharmacology, 1964, Volume: 42

    Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Brugada Syndrome; Calcium; Calcium Chloride; Cardiac Con

1964
Histamine antagonists as antiarrhythmic agents in ouabain cardiotoxicity in the cat.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cimetidine; Female; Histamine; Histamine Anta

1980
Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-and H2-receptor agonists and antagonists.
    European journal of pharmacology, 1975, Volume: 30, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Burimamide; Guinea Pigs; Heart; Heart Rate; Histamine; Histamine H1 A

1975
Clinical effects of diazepam prior to and during general anesthesia.
    Current therapeutic research, clinical and experimental, 1975, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Blood Pressure; Diazep

1975
Antiarrhythmic effect of hypertonic sodium bicarbonate and sodium chloride in ouabain-induced arrhythmias.
    Japanese heart journal, 1976, Volume: 17, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Bicarbonates; Cats; Disease Models, Animal; Electrocardiography; Mann

1976
Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart.
    Fundamental & clinical pharmacology, 1988, Volume: 2, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Coronary Diseas

1988
The pattern of cardiovascular alterations induced by infusion of platelet-activating factor in rabbit is modified by pretreatment with H1-H2 receptor antagonists but not by cyclooxygenase inhibition.
    Agents and actions, 1987, Volume: 21, Issue:1-2

    Topics: Animals; Arrhythmias, Cardiac; Cimetidine; Cyclooxygenase Inhibitors; Drug Interactions; Electrocard

1987
Adverse effects of meperidine, promethazine, and chlorpromazine for sedation in pediatric patients.
    Clinical pediatrics, 1985, Volume: 24, Issue:10

    Topics: Adolescent; Arrhythmias, Cardiac; Biopsy; Blood Pressure; Cardiac Catheterization; Child, Preschool;

1985
Antiarrhythmic & antiparkinsonian activity of two new promethazine salts.
    Indian journal of experimental biology, 1974, Volume: 12, Issue:6

    Topics: Animals; Anura; Arrhythmias, Cardiac; Central Nervous System; Dogs; Female; Guinea Pigs; Heart; Male

1974
Correlation of chemical structure of phenothiazines with their coronary dilator and antiarrhythmic activities.
    Japanese journal of pharmacology, 1971, Volume: 21, Issue:6

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chlorpromazine; Coronary Vessels;

1971
Management of anaesthesia for phaeochromocytoma.
    Anaesthesia, 1972, Volume: 27, Issue:1

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressur

1972
Observations on models used for the evaluation of antiarrhythmic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutte

1971
Anesthesia for pediatric ophthalmology.
    Annals of ophthalmology, 1971, Volume: 3, Issue:3

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Dissociative; Arrhythmias, Cardiac; Barbit

1971