Page last updated: 2024-11-03

promethazine and Apoplexy

promethazine has been researched along with Apoplexy in 5 studies

Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.

Research Excerpts

ExcerptRelevanceReference
"While the addition of low dose chlorpromazine and promethazine to standard of care for acute ischemic stroke did not have any significant improvement in functional outcomes, there were no serious adverse effects."9.30Low dose concomitant treatment with chlorpromazine and promethazine is safe in acute ischemic stroke. ( Chandra, A; Cheng, Z; Ding, Y; Du, H; Geng, X; Tong, Y; Zhu, H, 2019)
"While the addition of low dose chlorpromazine and promethazine to standard of care for acute ischemic stroke did not have any significant improvement in functional outcomes, there were no serious adverse effects."5.30Low dose concomitant treatment with chlorpromazine and promethazine is safe in acute ischemic stroke. ( Chandra, A; Cheng, Z; Ding, Y; Du, H; Geng, X; Tong, Y; Zhu, H, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
An, H1
Duan, Y1
Wu, D1
Yip, J3
Elmadhoun, O2
Wright, JC1
Shi, W1
Liu, K1
He, X1
Shi, J1
Jiang, F1
Ji, X2
Ding, Y4
Li, F2
Geng, X3
Zhu, H1
Chandra, A1
Cheng, Z1
Tong, Y1
Du, H1
Peng, C1
Shen, J1
Stavrovskaya, IG1
Narayanan, MV1
Zhang, W1
Krasnikov, BF1
Heemskerk, J1
Young, SS1
Blass, JP1
Brown, AM1
Beal, MF1
Friedlander, RM1
Kristal, BS1

Trials

1 trial available for promethazine and Apoplexy

ArticleYear
Low dose concomitant treatment with chlorpromazine and promethazine is safe in acute ischemic stroke.
    Journal of neurosurgical sciences, 2019, Volume: 63, Issue:3

    Topics: Adult; Aged; Aspirin; Atorvastatin; Chlorpromazine; Double-Blind Method; Drug Therapy, Combination;

2019

Other Studies

4 other studies available for promethazine and Apoplexy

ArticleYear
Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimental Stroke.
    Scientific reports, 2017, 08-07, Volume: 7, Issue:1

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Combined Modality Therapy; Disease Models, Animal; Hy

2017
Therapeutic Target and Cell-signal Communication of Chlorpromazine and Promethazine in Attenuating Blood-Brain Barrier Disruption after Ischemic Stroke.
    Cell transplantation, 2019, Volume: 28, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Chlorpromazine; Male; Promethazine; Rats; Rats, Spragu

2019
Neuroprotection by Chlorpromazine and Promethazine in Severe Transient and Permanent Ischemic Stroke.
    Molecular neurobiology, 2017, Volume: 54, Issue:10

    Topics: Animals; Chlorpromazine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ischemic Attac

2017
Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology.
    The Journal of experimental medicine, 2004, Jul-19, Volume: 200, Issue:2

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Apoptosis; Calcium; Calmodulin; Caspases; Cell

2004