promethazine has been researched along with Anaphylactic Reaction in 42 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Excerpt | Relevance | Reference |
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"To investigate the efficacy of the H1 antihistamine promethazine against early anaphylactic reactions to antivenom." | 9.09 | Sequential randomised and double blind trial of promethazine prophylaxis against early anaphylactic reactions to antivenom for bothrops snake bites. ( Cardoso, JL; Fan, HW; Ferrari, RA; França, FO; Malaque, CM; Marcopito, LF; Theakston, RD; Warrell, DA, 1999) |
"To investigate the efficacy of the H1 antihistamine promethazine against early anaphylactic reactions to antivenom." | 5.09 | Sequential randomised and double blind trial of promethazine prophylaxis against early anaphylactic reactions to antivenom for bothrops snake bites. ( Cardoso, JL; Fan, HW; Ferrari, RA; França, FO; Malaque, CM; Marcopito, LF; Theakston, RD; Warrell, DA, 1999) |
"The effects of mepyramine, promethazine, chlorpromazine and lysergic acid diethylamide have been compared on the capillary permeability changes of the skin, produced by histamine, by 5-hydroxytryptamine and by passive cutaneous anaphylaxis in mice." | 3.64 | On the nature of the chemical mediators involved in anaphylactic reactions in mice. ( HALPERN, BN; NEVEU, T; SPECTOR, S, 1963) |
"Envenoming from snakebites is most effectively treated by antivenom." | 2.76 | Low-dose adrenaline, promethazine, and hydrocortisone in the prevention of acute adverse reactions to antivenom following snakebite: a randomised, double-blind, placebo-controlled trial. ( Armitage, JM; Aronson, JK; de Silva, HA; de Silva, HJ; Hittharage, A; Jayamanne, S; Kalupahana, R; Lalloo, DG; Pathmeswaran, A; Ranasinha, CD; Ratnatilaka, GA; Samarakoon, SB; Uluwatthage, W, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (76.19) | 18.7374 |
1990's | 5 (11.90) | 18.2507 |
2000's | 2 (4.76) | 29.6817 |
2010's | 3 (7.14) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
de Silva, HA | 1 |
Pathmeswaran, A | 1 |
Ranasinha, CD | 1 |
Jayamanne, S | 1 |
Samarakoon, SB | 1 |
Hittharage, A | 1 |
Kalupahana, R | 1 |
Ratnatilaka, GA | 1 |
Uluwatthage, W | 1 |
Aronson, JK | 1 |
Armitage, JM | 1 |
Lalloo, DG | 1 |
de Silva, HJ | 1 |
Stuart Hannah, RC | 1 |
Heddle, R | 1 |
Smith, W | 1 |
Ellis, BC | 1 |
Brown, SG | 1 |
CIRSTEA, M | 4 |
HALPERN, BN | 1 |
NEVEU, T | 1 |
SPECTOR, S | 1 |
TORII, T | 1 |
KINOSHITA, S | 1 |
SUHACIU, G | 2 |
LEHKY, T | 1 |
ZMESKALOVA, D | 1 |
MALEK, J | 1 |
HERXHEIMER, H | 1 |
STRESEMANN, E | 1 |
ANDERSON, R | 1 |
HARDENBERGH, E | 1 |
Thong, CL | 1 |
Lambros, M | 1 |
Stewart, MG | 1 |
Kam, PC | 1 |
Williams, DJ | 1 |
Jensen, SD | 1 |
Nimorakiotakis, B | 1 |
Müller, R | 1 |
Winkel, KD | 1 |
BENACERRAF, B | 1 |
FISCHEL, EE | 1 |
Alexander, ER | 1 |
Fresh, JW | 1 |
Lewis, AJ | 1 |
Dervinis, A | 1 |
Rosenthale, ME | 1 |
Tryba, M | 1 |
Zevounou, F | 1 |
Zenz, M | 1 |
Damas, J | 2 |
Radermecker, M | 1 |
Lecomte, J | 3 |
Kelefiotis, D | 1 |
Vakirtzi-Lemonias, C | 1 |
Arunanthy, S | 1 |
Hertzberg, SR | 1 |
Fan, HW | 1 |
Marcopito, LF | 1 |
Cardoso, JL | 1 |
França, FO | 1 |
Malaque, CM | 1 |
Ferrari, RA | 1 |
Theakston, RD | 1 |
Warrell, DA | 1 |
Tong, KH | 1 |
Henricsson, A | 1 |
Bergentz, SE | 1 |
Pearn, J | 1 |
Hawgood, S | 1 |
Mandappa, JM | 1 |
Chandrasekhara, PM | 1 |
Nelvigi, RG | 1 |
Roberts, M | 1 |
Fisher, M | 1 |
Nolan, JC | 1 |
Stephens, DJ | 1 |
Proakis, AG | 1 |
Leonard, CA | 1 |
Johnson, DN | 1 |
Kilpatrick, BF | 1 |
Foxwell, MH | 1 |
Yanni, JM | 1 |
Schöning, B | 1 |
Lorenz, W | 1 |
Doenicke, A | 1 |
Mills, PJ | 1 |
Salmon, J | 2 |
Boroş, I | 1 |
Fregnan, GB | 1 |
Glässer, AH | 1 |
Julou, L | 1 |
Ducrot, R | 1 |
Bardone, MC | 1 |
Detaille, JY | 1 |
Feo, C | 1 |
Guyonnet, JC | 1 |
Loiseau, G | 1 |
Pasquet, J | 1 |
Harada, M | 1 |
Takeuchi, M | 1 |
Katagiri, K | 1 |
Takagi, K | 1 |
Fukao, T | 1 |
Colombi, PA | 1 |
Alonso, A | 1 |
Teo, SK | 1 |
Cheah, JS | 1 |
Pedersoli, WM | 1 |
Kelly, AJ | 1 |
Boman, A | 1 |
Tollackson, KA | 1 |
Frick, OL | 1 |
Dutta, D | 1 |
Bhargava, KC | 1 |
Chakravarti, RN | 1 |
Dhall, SR | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
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Low Dose Adrenaline, Promethazine, & Hydrocortisone (Alone and in Combination) to Prevent Acute Adverse Reactions to Antivenom in People Bitten by Snakes: Randomised, Double Blind, Placebo-Controlled Trial[NCT00270777] | Phase 4 | 1,000 participants (Anticipated) | Interventional | 2005-03-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for promethazine and Anaphylactic Reaction
Article | Year |
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[Histamine H1 and H2 receptor blockade as a supplementary premedication principle in elective surgery].
Topics: Adult; Anaphylaxis; Cimetidine; Clinical Trials as Topic; Dimethindene; Drug Eruptions; Histamine H1 | 1985 |
4 trials available for promethazine and Anaphylactic Reaction
Article | Year |
---|---|
Low-dose adrenaline, promethazine, and hydrocortisone in the prevention of acute adverse reactions to antivenom following snakebite: a randomised, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Anaphylaxis; Antivenins; Dose-Response Relationship, Drug; Double-Blind Method; E | 2011 |
[Prevention of anaphylactoid reactions using intramuscular promethazine and cimetidine. Studies of a histamine infusion model].
Topics: Adult; Anaphylaxis; Blood Pressure; Cimetidine; Drug Therapy, Combination; Hemodynamics; Histamine; | 1984 |
Sequential randomised and double blind trial of promethazine prophylaxis against early anaphylactic reactions to antivenom for bothrops snake bites.
Topics: Adolescent; Adult; Anaphylaxis; Animals; Antivenins; Bothrops; Child; Double-Blind Method; Female; H | 1999 |
[Histamine H1 and H2 receptor blockade as a supplementary premedication principle in elective surgery].
Topics: Adult; Anaphylaxis; Cimetidine; Clinical Trials as Topic; Dimethindene; Drug Eruptions; Histamine H1 | 1985 |
38 other studies available for promethazine and Anaphylactic Reaction
Article | Year |
---|---|
Fatal gas gangrene related to self-injection treatment of anaphylaxis.
Topics: Anaphylaxis; Clostridium perfringens; Epinephrine; Fatal Outcome; Female; Gas Gangrene; Humans; Inje | 2011 |
Parenteral antihistamines cause hypotension in anaphylaxis.
Topics: Adult; Anaphylaxis; Female; Histamine Antagonists; Humans; Hypotension; Infusions, Parenteral; Male; | 2013 |
[On the mechanism of the production of delayed death in anaphylactic shock in guinea pigs].
Topics: Anaphylaxis; Animals; Death; Guinea Pigs; Hypersensitivity; Immune System Diseases; Promethazine; Sh | 1962 |
On the nature of the chemical mediators involved in anaphylactic reactions in mice.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Capillary Permeability; Chlorpromazine; Histamine; Hista | 1963 |
[Emergency treatment in anaphylactoid shock].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aminophylline; Anaphylaxis; Anti-Allergic Agen | 1962 |
[On the mechanism of belated death due to anaphylacic shock in the guinea pig].
Topics: Anaphylaxis; Death; Guinea Pigs; Humans; Promethazine; Shock | 1962 |
STUDIES ON EXPERIMENTAL THERAPY OF ANAPHYLACTIC SHOCK IN DOGS.
Topics: Anaphylaxis; Angiotensins; Animals; Blood Transfusion; Dogs; Epinephrine; Horses; Hypoxia; Norepinep | 1963 |
[STUDY OF THE EFFECT OF DEXTRAN ON THE PATHOGENESIS OF ALLERGIC REACTIONS IN RATS].
Topics: Anaphylaxis; Anti-Allergic Agents; Cortisone; Dextrans; Histamine H1 Antagonists; Hypersensitivity; | 1963 |
THE EFFECT OF SOME NEW ANTIHISTAMINES ON THE ANAPHYLACTIC MICROSHOCK OF THE GUINEA-PIG.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Antipsychotic Agents; Cyclic S-Oxides; Cyproheptadine; G | 1963 |
ANAPHYLACTOID REACTION OF THE MOUSE TO DEXTRAN.
Topics: Anaphylaxis; Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesiology; Animals; C | 1964 |
An unexpected cause of an acute hypersensitivity reaction during recovery from anaesthesia.
Topics: Acute Disease; Aged; Anaphylaxis; Anesthesia Recovery Period; Anesthesia, Local; Anti-Allergic Agent | 2005 |
Antivenom use, premedication and early adverse reactions in the management of snake bites in rural Papua New Guinea.
Topics: Adolescent; Adult; Anaphylaxis; Animals; Antivenins; Child; Child, Preschool; Emergency Treatment; E | 2007 |
Effect of phenergan (N-dimethylamino-2-propyl-1-thiodiphenylamine, 3277 RP) on the Arthus reaction in rabbits.
Topics: Anaphylaxis; Animals; Arthus Reaction; Hypersensitivity; Immune System Diseases; Phenothiazines; Pro | 1949 |
Prevention of anaphylactic death in the mouse toxicity prevention test for TRIC agents.
Topics: Anaphylaxis; Animals; Biological Assay; Chlamydia; Chlorpromazine; Cortisone; Epinephrine; Mice; Pro | 1967 |
Bronchodilator and antiallergic effects of thiazinamium chloride in guinea pigs, rats, cats and dogs.
Topics: Anaphylaxis; Animals; Ascaris; Asthma; Bronchodilator Agents; Cats; Cromolyn Sodium; Dogs; Female; G | 1982 |
[Anaphylactic shock in brown Norway rats with reagins and no precipitins in the blood (author's transl)].
Topics: Anaphylaxis; Animals; Blood Pressure; Diethylcarbamazine; Immunoglobulin E; Indomethacin; Methysergi | 1980 |
In vivo responses of mouse blood cells to platelet-activating factor (PAF): role of the mediators of anaphylaxis.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Cells; Chlorpromazine; Erythroc | 1993 |
A life-threatening anaphylactoid reaction to polyvalent snake antivenom despite pretreatment.
Topics: Adult; Anaphylaxis; Antivenins; Epinephrine; Humans; Hydrocortisone; Male; Promethazine; Snake Venom | 1998 |
Angioedema/anaphylaxis.
Topics: Adult; Anaphylaxis; Angioedema; Australia; Child; Diphenhydramine; Epinephrine; Histamine H1 Antagon | 1999 |
The possible role of vasoactive substances for the hemodynamic effects of rapidly injected antilymphocyte globulin.
Topics: Anaphylaxis; Animals; Antilymphocyte Serum; Aspirin; Blood Cell Count; Blood Platelets; Dogs; Hemody | 1977 |
Bee-sting anaphylaxis in childhood.
Topics: Aerosols; Albuterol; Anaphylaxis; Bee Venoms; Bicarbonates; Child; Child, Preschool; Desensitization | 1979 |
Anaphylaxis to suxamethonium. Two case reports.
Topics: Adolescent; Adult; Anaphylaxis; Blood Pressure; Chlorpheniramine; Dexamethasone; Female; Gluconates; | 1975 |
Anaphylactoid reaction to iopamiro (after pretreatment).
Topics: Anaphylaxis; Cimetidine; Humans; Iopamidol; Male; Middle Aged; Prednisone; Premedication; Promethazi | 1992 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; C | 1989 |
Anaphylactoid reaction to oral premedication with temazepam and promethazine.
Topics: Adult; Anaphylaxis; Anti-Anxiety Agents; Female; Humans; Preanesthetic Medication; Promethazine; Tem | 1988 |
[Prostaglandins are not responsible for anaphylactic hypotension in the rat].
Topics: Anaphylaxis; Animals; Histamine H1 Antagonists; Hypotension; Indomethacin; Injections, Intravenous; | 1974 |
Influence of the drugs on the immuno-allergic reactivity. IV. The action of tranquillizers on passive anaphylaxis in guinea-pig.
Topics: Anaphylaxis; Animals; Chlordiazepoxide; Drug Evaluation, Preclinical; Guinea Pigs; Histamine; Histam | 1974 |
[On the eventually anaphylactic nature of the arterial hypotension induced by dextrans in the rat].
Topics: Aminocaproates; Anaphylaxis; Animals; Dextrans; Histamine Release; Hypotension; Methysergide; Promet | 1967 |
Synergistic action of an anti-5-hydroxytryptamine, anti-histamines and cortisone in experimental anaphylaxis.
Topics: Anaphylaxis; Animals; Aspirin; Body Temperature; Chlorpheniramine; Cortisone; Histamine H1 Antagonis | 1965 |
[Study of the pharmacological properties of 3-dimethylsulfonamido 10-(2-dimethylamino-propyl) phenothiazine (8.599 RP)].
Topics: Anaphylaxis; Animals; Central Nervous System; Guinea Pigs; Histamine H1 Antagonists; Mice; Parasympa | 1966 |
[Quantitative determination of passive cutaneous anaphylaxis and effects of anti-histaminics on anaphylaxis in guinea pigs].
Topics: Anaphylaxis; Animals; Capillary Permeability; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists | 1966 |
Effects of some drugs on capillary permeability in the anaphylaxis of the mouse.
Topics: Aminopyrine; Anaphylaxis; Animals; Anti-Inflammatory Agents; Antilymphocyte Serum; Aprotinin; Aspiri | 1971 |
[Action of diphenhydramine, chlorpheniramine, HS 592 and PB 400 on histamine and SRS-A induced wheals in skin of rats].
Topics: Anaphylaxis; Animals; Chlorpheniramine; Clemastine; Diphenhydramine; Histamine; Histamine H1 Antagon | 1972 |
Severe reaction to the bite of the triatomid bug (Triatoma rubrofasciata) in Singapore.
Topics: Adult; Anaphylaxis; Blood Pressure; Epinephrine; Humans; Hydrocortisone; Hypersensitivity; Insect Bi | 1973 |
Effects of acute anaphylactic shock on arterial blood pressure of anesthetized chickens.
Topics: Acetylcholine; Anaphylaxis; Anesthesia, Intravenous; Animals; Atropine; Blood Pressure; Chickens; Ch | 1973 |
Correspondence: Anaphylaxis under anaesthesia.
Topics: Adult; Anaphylaxis; Anesthesia, Intravenous; Bicarbonates; Dexamethasone; Drug Hypersensitivity; Fem | 1973 |
Response of human smooth muscle in Schultz-Dale experiments.
Topics: Allergens; Anaphylaxis; Antigen-Antibody Reactions; Atropine; Desensitization, Immunologic; Female; | 1966 |
Therapeutic studies in experimental amniotic fluid embolism in rabbits.
Topics: Anaphylaxis; Animals; Atropine; Bronchial Spasm; Disease Models, Animal; Electrocardiography; Emboli | 1970 |