promethazine has been researched along with Agitation, Psychomotor in 20 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression." | 8.93 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 8.85 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 8.82 | Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005) |
| "All medications produced a calming effect within one hour of administration, but only olanzapine and haloperidol reduced agitation by less than 10 points, and only olanzapine reduced aggression by less than four points in the first hour." | 5.15 | Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone. ( Baldaçara, L; Cordeiro, DC; Jackoswski, AP; Sanches, M, 2011) |
| " Midazolam was more rapidly sedating than haloperidol-promethazine, reducing the time people are exposed to aggression." | 5.10 | Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine. ( , 2003) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression." | 4.93 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 4.85 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 4.82 | Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005) |
| "Rectal thiopental is superior to this drug combination for pediatric sedation because it can be administered painlessly, has a more rapid onset and offset of action, and is of equal safety and efficacy at the dosage studied." | 2.67 | Rectal thiopental compared with intramuscular meperidine, promethazine, and chlorpromazine for pediatric sedation. ( Carey, BE; Falk, JL; Malone, LC; O'Brien, JF, 1991) |
| "Promethazine is an antihistamine with sedative properties that has no antiseizure effects and therefore can be administered before ECT to prevent the onset of agitation." | 1.33 | Promethazine for the treatment of agitation after electroconvulsive therapy: a case series. ( Amiaz, R; Grunhaus, L; Vishne, T, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 11 (55.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stetson, SR | 1 |
| Osser, DN | 1 |
| Dib, JE | 1 |
| Yaacoub, HE | 1 |
| Ikdais, WH | 1 |
| Atallah, E | 1 |
| Merheb, TJ | 1 |
| Ajaltouni, J | 1 |
| Akkari, M | 1 |
| Mourad, M | 1 |
| Nasr, ME | 1 |
| Hachem, D | 1 |
| Kazour, F | 1 |
| Tahan, F | 1 |
| Haddad, G | 1 |
| Azar, J | 1 |
| Zoghbi, M | 1 |
| Haddad, C | 1 |
| Hallit, S | 1 |
| Adams, CE | 6 |
| Bak, M | 1 |
| Weltens, I | 1 |
| Bervoets, C | 1 |
| De Fruyt, J | 1 |
| Samochowiec, J | 1 |
| Fiorillo, A | 1 |
| Sampogna, G | 1 |
| Bienkowski, P | 1 |
| Preuss, WU | 1 |
| Misiak, B | 1 |
| Frydecka, D | 1 |
| Samochowiec, A | 1 |
| Bak, E | 1 |
| Drukker, M | 1 |
| Dom, G | 1 |
| Szegő, A | 1 |
| Eleméry, M | 1 |
| Faludi, G | 1 |
| Kovács, G | 1 |
| Huf, G | 7 |
| Alexander, J | 5 |
| Gandhi, P | 1 |
| Allen, MH | 3 |
| Raveendran, NS | 2 |
| Coutinho, ES | 3 |
| Baldaçara, L | 1 |
| Sanches, M | 1 |
| Cordeiro, DC | 1 |
| Jackoswski, AP | 1 |
| Tharyan, P | 2 |
| Adams, C | 1 |
| John, T | 1 |
| Mol, C | 1 |
| Philip, J | 1 |
| Vishne, T | 1 |
| Amiaz, R | 1 |
| Grunhaus, L | 1 |
| Goswami, U | 1 |
| Channabasavanna, SM | 1 |
| Geist, ET | 1 |
| Gross, BD | 1 |
| Duggal, HS | 1 |
| da Silva Freire Coutinho, E | 1 |
| Fagundes, HM | 1 |
| Oliveira, ES | 1 |
| Lopez, JR | 1 |
| Gewandszajder, M | 1 |
| da Luz Carvalho, A | 1 |
| Keusen, A | 1 |
| O'Brien, JF | 1 |
| Falk, JL | 1 |
| Carey, BE | 1 |
| Malone, LC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915] | 314 participants (Actual) | Observational | 2017-08-01 | Completed | |||
| Rapid Tranquilization of Violent or Agitated People in Psychiatric Emergency Settings- A Pragmatic Randomized Controlled Trial of Intramuscular Olanzepine Vs. Intramuscular Haloperidol + Promethazine.[NCT00455234] | Phase 3 | 300 participants | Interventional | 2005-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for promethazine and Agitation, Psychomotor
| Article | Year |
|---|---|
Psychopharmacology of agitation in acute psychotic and manic episodes.
Topics: Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Ma | 2022 |
The pharmacological management of agitated and aggressive behaviour: A systematic review and meta-analysis.
Topics: Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; H | 2019 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; P | 2016 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; O | 2009 |
[Haloperidol plus promethazine for agitated patients--a systematic review].
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Haloperidol; | 2009 |
Haloperidol plus promethazine for psychosis induced aggression.
Topics: Aggression; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; Promethazine; Psyc | 2005 |
7 trials available for promethazine and Agitation, Psychomotor
| Article | Year |
|---|---|
Rapid tranquillisation in a psychiatric emergency hospital in Lebanon: TREC-Lebanon - a pragmatic randomised controlled trial of intramuscular haloperidol and promethazine
Topics: Antipsychotic Agents; Chlorpromazine; Haloperidol; Hospitals, Psychiatric; Humans; Lebanon; Prometha | 2022 |
Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone.
Topics: Adult; Aggression; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Dru | 2011 |
Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine.
Topics: Adult; Aggression; Drug Therapy, Combination; Emergency Service, Hospital; Emergency Services, Psych | 2003 |
Rapid tranquillisation of violent or agitated patients in a psychiatric emergency setting. Pragmatic randomised trial of intramuscular lorazepam v. haloperidol plus promethazine.
Topics: Antipsychotic Agents; Drug Therapy, Combination; Emergencies; Emergency Service, Hospital; Female; H | 2004 |
Rapid tranquillisation in psychiatric emergency settings in India: pragmatic randomised controlled trial of intramuscular olanzapine versus intramuscular haloperidol plus promethazine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Drug Combinations; Emergency Services, Psychiatric; Ha | 2007 |
Rapid tranquillisation in psychiatric emergency settings in Brazil: pragmatic randomised controlled trial of intramuscular haloperidol versus intramuscular haloperidol plus promethazine.
Topics: Adult; Aggression; Antipsychotic Agents; Drug Combinations; Emergency Services, Psychiatric; Haloper | 2007 |
Rectal thiopental compared with intramuscular meperidine, promethazine, and chlorpromazine for pediatric sedation.
Topics: Administration, Rectal; Blood Gas Analysis; Child; Child, Preschool; Chlorpromazine; Double-Blind Me | 1991 |
7 other studies available for promethazine and Agitation, Psychomotor
| Article | Year |
|---|---|
[Emergency psychopharmacotherapy in Hungary -- preliminary data].
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clopenthixol; Droperidol; Drug Prescript | 2014 |
TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243].
Topics: Brazil; Clinical Protocols; Drug Combinations; Emergency Services, Psychiatric; Ethics, Research; Ha | 2002 |
Promethazine for the treatment of agitation after electroconvulsive therapy: a case series.
Topics: Adult; Aged; Drug Administration Schedule; Electroconvulsive Therapy; Female; Histamine H1 Antagonis | 2005 |
Is akathisia a forerunner of tardive dyskinesia? A clinical report with brief review of literature.
Topics: Akathisia, Drug-Induced; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Lithium; Male; | 1984 |
Reduction of ketamine-induced emergence phenomena by preoperative promethazine.
Topics: Child; Child, Preschool; Double-Blind Method; Hallucinations; Humans; Ketamine; Nausea; Promethazine | 1982 |
Neuroleptic malignant syndrome precipitated by promethazine and lorazepam.
Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Basal Ganglia Diseases; Histamine H1 Antagonists; | 2001 |
Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study.
Topics: Aggression; Benzodiazepines; Brazil; Clinical Protocols; Drug Combinations; Drug Utilization; Emerge | 2002 |