promethazine has been researched along with Aggression in 16 studies
Promethazine: A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
promethazine : A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression." | 8.93 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 8.85 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 8.82 | Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005) |
| "All medications produced a calming effect within one hour of administration, but only olanzapine and haloperidol reduced agitation by less than 10 points, and only olanzapine reduced aggression by less than four points in the first hour." | 5.15 | Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone. ( Baldaçara, L; Cordeiro, DC; Jackoswski, AP; Sanches, M, 2011) |
| " Midazolam was more rapidly sedating than haloperidol-promethazine, reducing the time people are exposed to aggression." | 5.10 | Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine. ( , 2003) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression." | 4.93 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Gandhi, P; Huf, G, 2016) |
| "Haloperidol in combination with promethazine, and olanzapine, are effective in psychotic agitation, although haloperidol plus promethazine has a more rapid onset of effect faster; lorazepam is effective in non-psychotic agitation, aggression or excitement as well as in acute agitation of unknown origin." | 4.87 | [Rapid tranquillisation; review of the literature and recommendations]. ( Bak, M; Marcelis, M; van Os, J, 2011) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 4.85 | Haloperidol plus promethazine for psychosis-induced aggression. ( Alexander, J; Allen, MH; Huf, G; Raveendran, NS, 2009) |
| "To examine whether haloperidol plus promethazine is an effective treatment for psychosis induced agitation/aggression." | 4.82 | Haloperidol plus promethazine for psychosis induced aggression. ( Alexander, J; Allen, MH; Huf, G, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jürgens, G | 1 |
| Bauer, JØ | 1 |
| Bak, M | 2 |
| Weltens, I | 1 |
| Bervoets, C | 1 |
| De Fruyt, J | 1 |
| Samochowiec, J | 1 |
| Fiorillo, A | 1 |
| Sampogna, G | 1 |
| Bienkowski, P | 1 |
| Preuss, WU | 1 |
| Misiak, B | 1 |
| Frydecka, D | 1 |
| Samochowiec, A | 1 |
| Bak, E | 1 |
| Drukker, M | 1 |
| Dom, G | 1 |
| Huf, G | 5 |
| Alexander, J | 3 |
| Gandhi, P | 1 |
| Allen, MH | 3 |
| Raveendran, NS | 1 |
| Baldaçara, L | 1 |
| Sanches, M | 1 |
| Cordeiro, DC | 1 |
| Jackoswski, AP | 1 |
| van Os, J | 1 |
| Marcelis, M | 1 |
| Georgieva, I | 1 |
| Mulder, CL | 1 |
| Noorthoorn, E | 1 |
| Coutinho, ES | 1 |
| Adams, CE | 2 |
| Kinze, W | 1 |
| Mogilnicka, E | 1 |
| Boissard, CG | 1 |
| Waldmeier, PC | 1 |
| Delini-Stula, A | 1 |
| da Silva Freire Coutinho, E | 1 |
| Fagundes, HM | 1 |
| Oliveira, ES | 1 |
| Lopez, JR | 1 |
| Gewandszajder, M | 1 |
| da Luz Carvalho, A | 1 |
| Keusen, A | 1 |
| Boissier, JR | 1 |
| Simon, P | 1 |
| Rault, B | 1 |
| Barnett, A | 1 |
| Malick, JB | 1 |
| Taber, RI | 1 |
| Braud, WG | 1 |
| Weibel, JE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915] | 314 participants (Actual) | Observational | 2017-08-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for promethazine and Aggression
| Article | Year |
|---|---|
The pharmacological management of agitated and aggressive behaviour: A systematic review and meta-analysis.
Topics: Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; H | 2019 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; P | 2016 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; O | 2009 |
[Rapid tranquillisation; review of the literature and recommendations].
Topics: Aggression; Benzodiazepines; Conscious Sedation; Drug Therapy, Combination; Haloperidol; Humans; Hyp | 2011 |
Haloperidol plus promethazine for psychosis induced aggression.
Topics: Aggression; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; Promethazine; Psyc | 2005 |
4 trials available for promethazine and Aggression
| Article | Year |
|---|---|
Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone.
Topics: Adult; Aggression; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Dru | 2011 |
Reducing seclusion through involuntary medication: a randomized clinical trial.
Topics: Adult; Aggression; Antipsychotic Agents; Coercion; Drug Therapy, Combination; Female; Haloperidol; H | 2013 |
Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine.
Topics: Adult; Aggression; Drug Therapy, Combination; Emergency Service, Hospital; Emergency Services, Psych | 2003 |
Rapid tranquillisation in psychiatric emergency settings in Brazil: pragmatic randomised controlled trial of intramuscular haloperidol versus intramuscular haloperidol plus promethazine.
Topics: Adult; Aggression; Antipsychotic Agents; Drug Combinations; Emergency Services, Psychiatric; Haloper | 2007 |
7 other studies available for promethazine and Aggression
| Article | Year |
|---|---|
[Haloperidol and promethazine in psychotic aggression].
Topics: Aggression; Antipsychotic Agents; Drug Therapy, Combination; Haloperidol; Humans; Promethazine; Psyc | 2017 |
[Therapy with psychotropic drugs in children with "behavior disorders"].
Topics: Aggression; Amphetamines; Antipsychotic Agents; Child; Child Behavior Disorders; Chlorpromazine; Hal | 1981 |
The effects of single and repeated doses of maprotiline, oxaprotiline and its enantiomers on foot-shock induced fighting in rats.
Topics: Aggression; Animals; Anthracenes; Atropine; Cerebral Cortex; Electroshock; Humans; Male; Maprotiline | 1983 |
Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study.
Topics: Aggression; Benzodiazepines; Brazil; Clinical Protocols; Drug Combinations; Drug Utilization; Emerge | 2002 |
[Effect of various antihistaminics on the electroshock-induced fighting test in mice].
Topics: Aggression; Animals; Anthracenes; Diphenhydramine; Electroshock; Histamine H1 Antagonists; Humans; H | 1968 |
Effects of antihistamines on isolation-induced fighting in mice.
Topics: Aggression; Animals; Behavior, Animal; Cyproheptadine; Diphenhydramine; Histamine H1 Antagonists; Hu | 1971 |
Acquired stimulus control of drug-induced changes in aggressive display in betta splendens.
Topics: Aggression; Animals; Behavior, Animal; Color; Conditioning, Classical; Conditioning, Psychological; | 1969 |