Page last updated: 2024-11-03

promazine and Schizophrenia

promazine has been researched along with Schizophrenia in 58 studies

Promazine: A phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.
promazine : A phenothiazine deriative in which the phenothiazine tricycle has a 3-(dimethylaminopropyl) group at the N-10 position.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

Excerpt	Relevance	Reference
" Improvement was recorded in a double blind study of 18 patients treated with maximum tolerated dosage (mean 18."	2.64	Tardive dyskinesia treated with pimozide. ( Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF, 1975)
"(ii) The effect of schizophrenia is to increase MAE duration, and this is not due to some peripheral artefact."	2.39	The duration of the movement aftereffect as an index of psychiatric illness. ( Harris, J, 1994)
"Priapism is a rare but serious adverse effect of psychotropic drugs resulting from their peripheral alpha-adrenoreceptor blocking action."	1.27	Priapism and psychotropic medication. ( de Alwis, C; Kogeorgos, J, 1986)
"As outpatient treatment of schizophrenia increases, cases of over-dose with phenothiazine drugs may be expected to increase also."	1.25	Phenothiazine poisoning. A review of 48 cases. ( Barry, D; Becker, CE; Meyskens, FL, 1973)

Research

Studies (58)

Timeframe	Studies, this research(%)	All Research%
pre-1990	57 (98.28)	18.7374
1990's	1 (1.72)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
BARSA, JA	2
KLINE, NS	2
MANGUN, CW	1
WEBB, WW	1
SIBILIO, JP	2
ANDREW, G	1
DART, D	2
MOORE, KB	2
STEHMAN, VA	2
ANDREW, O	1
SIMPSON, RW	1
JESSON, JG	1
URQUHART, R	1
FORREST, AD	1
WINFIELD, DL	1
AIVAZIAN, GH	2
FLEMING, BG	1
SPENCER, AM	1
WHITELAW, EM	1
GILMORE, TH	1
SHATIN, L	1
HARGREAVES, MA	1
KJENAAS, EA	2
MCHUGH, RB	2
REESE, HC	1
APFELDORF, M	1
BAUER, HG	1
McGAVACK, TH	1
CASEY, JF	1
BENNETT, IF	1
LINDLEY, CJ	1
HOLLISTER, LE	1
GORDON, MH	1
SPRINGER, NN	1
ENGELHARDT, DM	11
FREEDMAN, N	13
HANKOFF, LD	2
GLICK, BS	1
KAYE, HE	1
BUCHWALD, J	1
BATTISTI, A	1
ROSSI, M	1
MANN, D	5
MARGOLIS, R	10
ENGELHARDT, D	2
ROSEN, B	6
WHITE, PT	2
DEMYER, W	1
DEMYER, M	1
INVERNIZZI, G	1
GITTELMAN, RK	1
KLEIN, DF	2
POLLACK, M	1
NEUMANN, H	1
NISTRI, M	1
DELUCA, PL	1
BORDELEAU, JM	1
FARETRA, G	1
GOZUN, C	1
LERNER, J	1
KOSTIKOVA, LF	1
ONHEIBER, P	1
DEMYER, MK	1
OTTINGER, DR	1
GANTZ, RS	1
BIRKETT, DP	1
LONDON, S	1
Logothetis, J	1
Harris, J	1
Gardos, G	1
Cole, JO	1
Claveria, LE	1
Teychenne, PF	1
Calne, DB	1
Haskayne, L	1
Petrie, A	1
Pallis, CA	1
Lodge-Patch, IC	1
Davis, JM	1
Kogeorgos, J	1
de Alwis, C	1
Snyder, S	1
Greenberg, D	2
Yamamura, HI	1
Snyder, SH	1
Yamumura, HI	1
Stille, G	1
Behrman, S	1
Barry, D	1
Meyskens, FL	1
Becker, CE	1
Rudorfer, L	2
Paley, HM	2
Turano, P	1
Turner, WJ	1
Manian, AA	1
Deberdt, R	1
Margolis, RA	2
Cutler, R	2
Engelhart, DM	1
Krystof, J	1
Zyg, J	1
Mitkiewicz, S	1
Kaczyński, J	1
Simmelsgaard, H	1
Mellergaard, M	1
Vangtorp, A	1
Dragon, P	1
Cohen, M	1
Salzberger, GJ	1

Reviews

4 reviews available for promazine and Schizophrenia

Article	Year
EFFECTS OF PSYCHOTROPIC DRUGS ON LONG-TERM ADJUSTMENT. A REVIEW. Psychopharmacologia, 1964, Apr-03, Volume: 5 Topics: Chlorpromazine; Electroconvulsive Therapy; Hospitals, Psychiatric; Imipramine; Mental Disorders; Phe	1964
The duration of the movement aftereffect as an index of psychiatric illness. Perception, 1994, Volume: 23, Issue:10 Topics: Adult; Antiparkinson Agents; Attention; Chlorpromazine; Dopamine; Eye Movements; Female; Fixation, O	1994
Maintenance antipsychotic therapy: is the cure worse than the disease? The American journal of psychiatry, 1976, Volume: 133, Issue:1 Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Chronic Disease; Clinical Trials as To	1976
Antischizophrenic drugs and brain cholinergic receptors. Affinity for muscarinic sites predicts extrapyramidal effects. Archives of general psychiatry, 1974, Volume: 31, Issue:1 Topics: Animals; Antipsychotic Agents; Butyrophenones; Chemical Phenomena; Chemistry; Chlorpromazine; Dibenz	1974

Trials

11 trials available for promazine and Schizophrenia

Article	Year
Maintenance antipsychotic therapy: is the cure worse than the disease? The American journal of psychiatry, 1976, Volume: 133, Issue:1 Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Chronic Disease; Clinical Trials as To	1976
Tardive dyskinesia treated with pimozide. Journal of the neurological sciences, 1975, Volume: 24, Issue:4 Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousnes	1975
Recent developments in the drug treatment of schizophrenia. The American journal of psychiatry, 1976, Volume: 133, Issue:2 Topics: Chlorpromazine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Drug Re	1976
Prediction of psychiatric hospitalization. II. The Hospitalization Proneness Scale: a cross-validation. Journal of abnormal psychology, 1972, Volume: 80, Issue:3 Topics: Adolescent; Adult; Chlorpromazine; Hospitalization; Hospitals, Psychiatric; Humans; Placebos; Probab	1972
Physician bias and the double-blind. Archives of general psychiatry, 1969, Volume: 20, Issue:3 Topics: Adult; Attitude of Health Personnel; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Male;	1969
On the modification of paranoid symptomatology. II. Stylistic considerations and the effectiveness of phenothiazines. The Journal of nervous and mental disease, 1970, Volume: 150, Issue:1 Topics: Adolescent; Adult; Aggression; Analysis of Variance; Chlorpromazine; Clinical Trials as Topic; Cogni	1970
The hospitalization proneness scale as a predictor of response to phenothiazine treatment. II. Delay of psychiatric hospitalization. The Journal of nervous and mental disease, 1971, Volume: 152, Issue:6 Topics: Adolescent; Adult; Ambulatory Care; Analysis of Variance; Chlorpromazine; Cognition; Hospitalization	1971
Phenothiazines in prevention of psychiatric hospitalization. IV. Delay or prevention of hospitalization--a reevaluation. Archives of general psychiatry, 1967, Volume: 16, Issue:1 Topics: Chlorpromazine; Clinical Trials as Topic; Hospitalization; Humans; Placebos; Promazine; Schizophreni	1967
[Buronil (FG 5111)--a new butyrophenone derivative. A controlled clinical study on senile dementia and confusion]. Nordisk medicin, 1967, Feb-16, Volume: 77, Issue:7 Topics: Aged; Butyrophenones; Clinical Trials as Topic; Dementia; Female; Humans; Male; Promazine; Schizophr	1967
On the modification of paranoid symptomatology. The Journal of nervous and mental disease, 1967, Volume: 144, Issue:1 Topics: Adolescent; Adult; Aggression; Chlorpromazine; Cognition; Factor Analysis, Statistical; Humans; Para	1967
Family interaction patterns, drug treatment, and change in social aggression. Archives of general psychiatry, 1968, Volume: 19, Issue:1 Topics: Adolescent; Adult; Aggression; Analysis of Variance; Chlorpromazine; Conflict, Psychological; Family	1968

Other Studies

44 other studies available for promazine and Schizophrenia

Article	Year
Promazine in chronic schizophrenic patients. The American journal of psychiatry, 1957, Volume: 113, Issue:7 Topics: Phenothiazines; Promazine; Schizophrenia	1957
Promazine in chronic schizophrenic patients. The American journal of psychiatry, 1957, Volume: 113, Issue:7 Topics: Phenothiazines; Promazine; Schizophrenia	1957
Promazine in chronic schizophrenic patients. The American journal of psychiatry, 1957, Volume: 113, Issue:7 Topics: Phenothiazines; Promazine; Schizophrenia	1957
Promazine in chronic schizophrenic patients. The American journal of psychiatry, 1957, Volume: 113, Issue:7 Topics: Phenothiazines; Promazine; Schizophrenia	1957
Promazine hydrochloride in the treatment of chronic catatonic schizophrenics. The Journal of nervous and mental disease, 1956, Volume: 123, Issue:6 Topics: Catatonia; Humans; Phenothiazines; Promazine; Schizophrenia	1956
Treatment of chronic schizophrenia with promazine hydrochloride. A.M.A. archives of neurology and psychiatry, 1957, Volume: 78, Issue:4 Topics: Phenothiazines; Promazine; Schizophrenia	1957
Effects of promazine hydrochloride on attention in chronic schizophrenia. A.M.A. archives of neurology and psychiatry, 1959, Volume: 81, Issue:1 Topics: Attention; Phenothiazines; Promazine; Schizophrenia	1959
The effects of promazine (sparine) in chronic schizophrenia. The Journal of mental science, 1958, Volume: 104, Issue:437 Topics: Phenothiazines; Promazine; Schizophrenia	1958
Clinical trial of promazine hydrochloride and acetylpromazine in chronic schizophrenic patients. The Journal of mental science, 1959, Volume: 105, Issue:438 Topics: Acepromazine; Phenothiazines; Promazine; Schizophrenia	1959
EEG changes associated with intensive promazine therapy. American practitioner and digest of treatment, 1959, Volume: 10, Issue:7 Topics: Electroencephalography; Phenothiazines; Promazine; Schizophrenia	1959
A controlled comparative investigation of the effects of promazine, chlorpromazine, and a placebo in chronic psychosis. The Journal of mental science, 1959, Volume: 105, Issue:439 Topics: Chlorpromazine; Phenothiazines; Promazine; Psychotic Disorders; Schizophrenia	1959
Quantitative comparison of clinical effectiveness of chlorpromazine and promazine. The Journal of mental science, 1959, Volume: 105, Issue:439 Topics: Chlorpromazine; Humans; Phenothiazines; Promazine; Schizophrenia; Treatment Outcome	1959
An evaluation of the double-blind trial as a method of assessing promazine ("Sparine") in the treatment of chronic psychotic patients. The Journal of mental science, 1961, Volume: 107 Topics: Chronic Disease; Double-Blind Method; Mental Disorders; Promazine; Schizophrenia	1961
The effect of promazine (Sparine) on patients with chronic schizophrenia. Minnesota medicine, 1960, Volume: 43 Topics: Minnesota; Promazine; Schizophrenia	1960
Clinical evaluation of promazine therapy for schizophrenia. Diseases of the nervous system, 1959, Volume: 20 Topics: Promazine; Schizophrenia	1959
Methoxypromazine in chronic schizophrenia. The American journal of psychiatry, 1960, Volume: 117 Topics: Phenothiazines; Promazine; Schizophrenia	1960
Drug therapy in schizophrenia. A controlled study of the relative effectiveness of chlorpromazine, promazine, phenobarbital, and placebo. A.M.A. archives of general psychiatry, 1960, Volume: 2 Topics: Chlorpromazine; Phenobarbital; Promazine; Research Design; Schizophrenia; Tranquilizing Agents	1960
The treatment of schizophrenic out-patients with promazine and reserpine. The Psychiatric quarterly, 1959, Volume: 33 Topics: Humans; Outpatients; Promazine; Reserpine; Schizophrenia	1959
[Interpretative possibilities on the therapeutic action of certain neuroplegic drugs in schizophrenia]. Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1962, Mar-31, Volume: 86 Topics: Promazine; Schizophrenia; Tranquilizing Agents	1962
LONG TERM DRUG-INDUCED SYMPTOM MODIFICATION IN SCHIZOPHRENIC OUTPATIENTS. The Journal of nervous and mental disease, 1963, Volume: 137 Topics: Chlorpromazine; Humans; Outpatients; Placebos; Promazine; Schizophrenia	1963
THE INFLUENCE OF PREVIOUS HOSPITALIZATION ON THE CLINICAL COURSE OF PSYCHOPHARMACOLOGICALLY TREATED SCHIZOPHRENIC OUTPATIENTS. Comprehensive psychiatry, 1963, Volume: 4 Topics: Chlorpromazine; Hospitalization; Humans; Outpatients; Placebos; Promazine; Psychopharmacology; Schiz	1963
PHENOTHIAZINES IN PREVENTION OF PSYCHIATRIC HOSPITALIZATION. II. DURATION OF TREATMENT EXPOSURE. JAMA, 1963, Dec-14, Volume: 186 Topics: Antipsychotic Agents; Chlorpromazine; Hospitalization; Hospitals, Psychiatric; Humans; Phenothiazine	1963
EEG ABNORMALITIES IN EARLY CHILDHOOD SCHIZOPHRENIA: A DOUBLE-BLIND STUDY OF PSYCHIATRICALLY DISTURBED AND NORMAL CHILDREN DURING PROMAZINE SEDATION. The American journal of psychiatry, 1964, Volume: 120 Topics: Autistic Disorder; Child; Child Behavior Disorders; Child, Preschool; Double-Blind Method; Electroen	1964
[OBSERVATIONS ON THE USE OF PHENYLPYRROLIDINOPENTANE AS AN ANTIASTHENIC AGENT IN TREATMENT WITH PSYCHOPHARMACOLOGICAL DRUGS]. Gazzetta medica italiana, 1964, Volume: 123 Topics: Amitriptyline; Anxiety; Anxiety Disorders; Asthenia; Bipolar Disorder; Chemical and Drug Induced Liv	1964
[A PSYCHIATRIC EMERGENCY SITUATION: THE START OF THE SCHIZOPHRENIC ATTACK]. Therapie der Gegenwart, 1964, Volume: 103 Topics: Chlorprothixene; Diagnosis; Haloperidol; Humans; Promazine; Schizophrenia; Tranquilizing Agents	1964
[APROPOS OF THE INHIBITION OF EJACULATION DURING THIORIDAZINE TREATMENT: ITS POSSIBLE THERAPEUTIC VALUE]. L'Encephale, 1964, Volume: 53 Topics: Anura; Chlorpromazine; Ejaculation; Gonadotropins; Humans; Pharmacology; Promazine; Rabbits; Rats; R	1964
[STUDY OF POST-RECOVERY CARE IN A GROUP OF PSYCHOTIC PATIENTS]. L'union medicale du Canada, 1964, Volume: 93 Topics: Depressive Disorder, Major; Humans; Outpatient Clinics, Hospital; Promazine; Psychotic Disorders; Sc	1964
THE USE OF DRUG COMBINATIONS IN PEDIATRIC PSYCHIATRY. Current therapeutic research, clinical and experimental, 1964, Volume: 6 Topics: Adolescent; Biomedical Research; Brain; Brain Damage, Chronic; Brain Injuries; Child; Child Behavior	1964
PHENOTHIAZINES IN PREVENTION OF PSYCHIATRIC HOSPITALIZATION. 3. DELAY OR PREVENTION OF HOSPITALIZATION. Archives of general psychiatry, 1964, Volume: 11 Topics: Antipsychotic Agents; Chlorpromazine; Drug Therapy; Hospitalization; Humans; Phenothiazines; Placebo	1964
SIDE REACTIONS TO THE PHENOTHIAZINES AND THE THERAPEUTIC USE OF ETHYL ALCOHOL. The American journal of psychiatry, 1965, Volume: 121 Topics: Drug Therapy; Ethanol; Fluphenazine; Movement Disorders; Parasympatholytics; Parkinsonian Disorders;	1965
[CLINICAL AND ELECTROENCEPHALOGRAPHIC STUDIES ON SCHIZOPHRENIC PATIENTS WITH CHRONIC VERBAL HALLUCINOSIS IN AMINAZIN AND PROPAZINE THERAPY]. Voprosy psikhiatrii i nevropatologii; sbornik trudov, 1964, Volume: 10 Topics: Chlorpromazine; Hallucinations; Promazine; Psychotic Disorders; Schizophrenia; Triazines	1964
SLEEP AND DREAM PATTERNS OF CHILD SCHIZOPHRENICS. Archives of general psychiatry, 1965, Volume: 12 Topics: Child; Dreams; Drug Therapy; Electroencephalography; Eye Movements; Humans; Neurophysiology; Promazi	1965
PHENOTHIAZINE REDUCTION AS A CAUSE OF REHOSPITALIZATION. Archives of general psychiatry, 1965, Volume: 12 Topics: Chlorpromazine; Drug Therapy; Fluphenazine; Hospitalization; Humans; Perphenazine; Phenothiazines; P	1965
COMMUNICATION OF BODY COMPLAINTS AND PARANOID SYMPTOM CHANGE UNDER CONDITIONS OF PHENOTHIAZINE TREATMENT. Journal of personality and social psychology, 1965, Volume: 1 Topics: Biomedical Research; Chlorpromazine; Cognition; Communication; Drug Therapy; Humans; Paranoid Disord	1965
The effect of promazine (spraine) on patients with chronic schizophrenia. Minnesota medicine, 1960, Volume: 43 Topics: Minnesota; Promazine; Schizophrenia	1960
Spontaneous epileptic seizures and electroencephalographic changes in the course of phenothiazine therapy. Neurology, 1967, Volume: 17, Issue:9 Topics: Adult; Bipolar Disorder; Brain Damage, Chronic; Chlorpromazine; Electroconvulsive Therapy; Electroen	1967
Priapism and psychotropic medication. The British journal of psychiatry : the journal of mental science, 1986, Volume: 149 Topics: Adult; Chlormethiazole; Chlorpromazine; Humans; Male; Munchausen Syndrome; Priapism; Promazine; Schi	1986
Antischizophrenic drugs: affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects. Journal of psychiatric research, 1974, Volume: 11 Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Binding, Competitive; Brain; Chlorpromazine;	1974
[Neuroleptic therapy of schizophrenia from pharmacological viewpoint]. Schweizerische medizinische Wochenschrift, 1969, Nov-15, Volume: 99, Issue:46 Topics: Animals; Apomorphine; Arousal; Caudate Nucleus; Chlorpromazine; Chlorprothixene; Electroencephalogra	1969
Mutism induced by phenothiazines. The British journal of psychiatry : the journal of mental science, 1972, Volume: 121, Issue:565 Topics: Adult; Antipsychotic Agents; Chlorpromazine; Depression; Female; Humans; Hyperemesis Gravidarum; Int	1972
Phenothiazine poisoning. A review of 48 cases. California medicine, 1973, Volume: 118, Issue:1 Topics: Adult; Antipsychotic Agents; Child; Child, Preschool; Chlorpromazine; Female; Humans; Male; Poisonin	1973
Thin-layer chromatography of chlorpromazine metabolites. Attempt to identify each of the metabolites appearing in blood, urine and feces of chronically medicated schizophrenics. Journal of chromatography, 1973, Jan-17, Volume: 75, Issue:2 Topics: Chlorpromazine; Chromatography, Gas; Chromatography, Thin Layer; Chronic Disease; Erythrocytes; Fece	1973
Lorazepam in the treatment of severe anxiety and anxiety associated with psychotic conditions. Current medical research and opinion, 1973, Volume: 1, Issue:5 Topics: Adult; Aggression; Amitriptyline; Anxiety Disorders; Ataxia; Benzodiazepinones; Bipolar Disorder; Ch	1973
Withdrawal symptoms after long-term treatment with neuroleptics. Polish medical journal, 1972, Volume: 11, Issue:1 Topics: Adult; Aged; Blood Circulation; Chlorpromazine; Fever; Humans; Hyperkinesis; Hypotension; Hypothermi	1972
[Effectiveness of intravenouly administered promazine in acute psychomotor agitation]. Psychiatria polska, 1971, Volume: 5, Issue:2 Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Chronic Disease; Drug Antagonism; Electroconvul	1971
The hospitalization proneness scale as a predictor of response to phenothiazine treatment. The Journal of nervous and mental disease, 1968, Volume: 146, Issue:6 Topics: Adolescent; Adult; Chlorpromazine; Hospitalization; Hospitals, Psychiatric; Humans; Phenothiazines;	1968
Long term control of agitation in senile psychoses. Diseases of the nervous system, 1966, Volume: 27, Issue:1 Topics: Aged; Behavior; Dementia; Female; Geriatrics; Humans; Promazine; Schizophrenia	1966