prolylarginine has been researched along with Amyotrophic Lateral Sclerosis in 4 studies
*Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C; Harada, Y; Hayamizu, Y; Kanekura, K; Kuroda, M; Li, P; Miyagi, T; Narumi, S; Sugimoto, M; Tezuka, S; Ueda, K; Yamanaka, Y | 1 |
| Hayamizu, Y; Kanekura, K; Kuroda, M | 1 |
| Andersen, JW; Antognetti, G; Carlomagno, Y; Castanedes-Casey, M; Chew, J; Datta, A; Daughrity, LM; DeTure, M; Dickson, DW; Fryer, JD; Gachechiladze, MA; Gendron, TF; Gonzales, PK; Guo, L; Jansen-West, K; Kampmann, M; Kurti, A; Lin, WL; Link, CD; Ludwig, C; McCampbell, A; O'Raw, AD; Oskarsson, B; Petrucelli, L; Pickles, SR; Prudencio, M; Rademakers, R; Shorter, J; Song, Y; Tian, R; Tong, J; Ward, ME; Wu, Y; Yue, M; Zhang, YJ | 1 |
| Underwood, E | 1 |
1 review(s) available for prolylarginine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Order controls disordered droplets: structure-function relationships in
Topics: Amyotrophic Lateral Sclerosis; Animals; C9orf72 Protein; Dipeptides; Frontotemporal Dementia; Humans; Neurodegenerative Diseases; Peptide Fragments; Structure-Activity Relationship | 2022 |
3 other study(ies) available for prolylarginine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine.
Topics: Amyotrophic Lateral Sclerosis; Arginine; C9orf72 Protein; Cell Line; Cell Nucleolus; Dipeptides; HEK293 Cells; Humans; Peptides; Proteomics | 2021 |
Heterochromatin anomalies and double-stranded RNA accumulation underlie
Topics: Amyotrophic Lateral Sclerosis; Animals; Brain; C9orf72 Protein; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Dipeptides; Disease Models, Animal; Green Fluorescent Proteins; HEK293 Cells; Heterochromatin; Humans; Mice; Mice, Inbred C57BL; Nuclear Lamina; Repetitive Sequences, Nucleic Acid; RNA, Double-Stranded | 2019 |
NEUROSCIENCE. Plugged pores may underlie some ALS, dementia cases.
Topics: Active Transport, Cell Nucleus; Amyotrophic Lateral Sclerosis; Animals; C9orf72 Protein; Dipeptides; Drosophila; Drosophila Proteins; Frontotemporal Dementia; GTPase-Activating Proteins; Humans; Mutation; Neurons; Nuclear Pore; Proteins; RNA | 2015 |