proline has been researched along with Protein Aggregation, Pathological in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 6 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Irie, K | 1 |
| Lindholm, D; Myöhänen, TT; Norrbacka, S | 1 |
| Adriaenssens, E; Antoniani, F; Asselbergh, B; Carra, S; Crippa, V; Mediani, L; Poletti, A; Tedesco, B; Timmerman, V | 1 |
| Fredrickson, GH; Han, S; Kosik, KS; McCarty, J; Rauch, JN; Shea, JE; Vigers, M; Wilson, MZ; Zhang, X | 1 |
| Alexey, UA; Alexey, VV; Boris, LV; Kristina, SN; Lyudmila, AA; Maxim, DE; Nikolay, MF; Valery, RV; Valery, SP; Vladimir, FM; Yuriy, DA | 1 |
| Anand, BG; Ansari, M; Behera, RK; Dubey, K; Kar, K; Panigrahi, A; Prajapati, KP; Purohit, S | 1 |
| Ding, X; Gu, S; Luo, SZ; Xue, S | 1 |
| Anglada-Huguet, M; Joseph, M; Mandelkow, E; Mandelkow, EM; Paesler, K | 1 |
| Funayama, M; Hattori, N; Li, Y; Matsuura, E; Nishioka, K; Takanashi, M; Takashima, H; Tsuyama, S; Yoshino, H | 1 |
| Berbić, S; Hasanbašić, S; Puizdar, V; Stoka, V; Taler-Verčič, A; Tušek Žnidarič, M; Vilfan, A; Žerovnik, E | 1 |
| Ichida, JK; Krishnamurthy, K; Lin, S; Markandaiah, SS; Monaghan, J; Pandey, UB; Pasinelli, P; Shi, Y; Shneider, NA; Tan, W; Trotti, D; Wen, X; Westergard, T | 1 |
| Bejerano-Sagie, M; Ben-Gedalya, T; Burstyn-Cohen, T; Cabral, WA; Cohen, E; Frere, S; Friedmann-Morvinski, D; Marini, JC; Moll, L; Slutsky, I | 1 |
| Choudhary, S; Hosur, RV; Kishore, N | 1 |
| Berbić, S; Hasanbašić, S; Stoka, V; Taler-Verčič, A; Turk, D; Žerovnik, E | 1 |
14 other study(ies) available for proline and Protein Aggregation, Pathological
| Article | Year |
|---|---|
New diagnostic method for Alzheimer's disease based on the toxic conformation theory of amyloid β.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies, Monoclonal; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Mice; Models, Molecular; Neurofibrillary Tangles; Peptide Fragments; Plaque, Amyloid; Proline; Protein Aggregates; Protein Aggregation, Pathological; Protein Structure, Tertiary | 2020 |
Prolyl oligopeptidase inhibition reduces PolyQ aggregation and improves cell viability in cellular model of Huntington's disease.
Topics: Acetylcysteine; Biocatalysis; Cell Survival; Cysteine Proteinase Inhibitors; HeLa Cells; Humans; Huntingtin Protein; Huntington Disease; Peptides; Proline; Prolyl Oligopeptidases; Proteasome Endopeptidase Complex; Protein Aggregates; Protein Aggregation, Pathological; Serine Endopeptidases; Trinucleotide Repeats | 2019 |
BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Autophagy; Cardiomyopathy, Dilated; Charcot-Marie-Tooth Disease; Codon; Distal Myopathies; HEK293 Cells; Humans; Molecular Chaperones; Mutation, Missense; Proline; Protein Aggregates; Protein Aggregation, Pathological; Protein Transport; Ubiquitination | 2020 |
The proline-rich domain promotes Tau liquid-liquid phase separation in cells.
Topics: Cell Separation; Humans; Liquid-Liquid Extraction; Microtubules; Neuroblastoma; Phosphorylation; Proline; Protein Aggregation, Pathological; Protein Binding; tau Proteins; Tumor Cells, Cultured | 2020 |
Phosphine modification of proline-glycine-proline tripeptide and study of its neuroprotective properties.
Topics: Cell Line, Tumor; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Oligopeptides; Phosphines; Proline; Protein Aggregation, Pathological | 2021 |
Osmoprotectant Coated Thermostable Gold Nanoparticles Efficiently Restrict Temperature-Induced Amyloid Aggregation of Insulin.
Topics: Amino Acid Sequence; Amyloid; Gold; Hydrophobic and Hydrophilic Interactions; Hydroxyproline; Insulin; Metal Nanoparticles; Molecular Docking Simulation; Proline; Protein Aggregation, Pathological; Protein Conformation; Surface Properties; Temperature; Thermodynamics | 2021 |
Disease-associated mutations affect TIA1 phase separation and aggregation in a proline-dependent manner.
Topics: Amyloid; Cytoplasmic Granules; Inclusion Bodies; Liquid-Liquid Extraction; Mutation; Proline; Protein Aggregates; Protein Aggregation, Pathological; Protein Domains; Stress Granules; T-Cell Intracellular Antigen-1 | 2021 |
Anti-aggregant tau mutant promotes neurogenesis.
Topics: Amino Acid Motifs; Animals; Astrocytes; Hippocampus; Humans; Mice; Mice, Transgenic; Microglia; Mutant Proteins; Neural Stem Cells; Neurogenesis; Proline; Protein Aggregation, Pathological; Protein Conformation; Protein Conformation, beta-Strand; Protein Domains; Repetitive Sequences, Amino Acid; tau Proteins; Tauopathies | 2017 |
Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations.
Topics: Aged; alpha-Synuclein; Astrocytes; Autopsy; DNA-Binding Proteins; Female; Gene Expression Regulation; Histidine; Homozygote; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Parkinsonian Disorders; Proline; Protein Aggregation, Pathological; Substantia Nigra; tau Proteins | 2018 |
Prolines Affect the Nucleation Phase of Amyloid Fibrillation Reaction; Mutational Analysis of Human Stefin B.
Topics: Amyloid; Cystatin B; DNA Mutational Analysis; Humans; Mutation; Proline; Protein Aggregation, Pathological | 2019 |
Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death.
Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Antisense Elements (Genetics); Arginine; C9orf72 Protein; Cell Death; Dipeptides; DNA Repeat Expansion; Drosophila melanogaster; Frontotemporal Dementia; Humans; Motor Neurons; Neurons; Primary Cell Culture; Proline; Protein Aggregation, Pathological; Proteins; Spinal Cord | 2014 |
Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction.
Topics: Alzheimer Disease; Amino Acid Substitution; Animals; Brain; Cell Line; Mice; Mice, Knockout; Molecular Chaperones; Presenilin-1; Proline; Protein Aggregation, Pathological; Protein Folding | 2015 |
Inhibition of insulin fibrillation by osmolytes: Mechanistic insights.
Topics: Amyloid; Betaine; Calorimetry; Insulin; Kinetics; Models, Biological; Osmolar Concentration; Proline; Protein Aggregation, Pathological; Protein Binding; Sorbitol | 2015 |
Proline Residues as Switches in Conformational Changes Leading to Amyloid Fibril Formation.
Topics: Amino Acid Sequence; Amyloid; Animals; beta 2-Microglobulin; Cystatin B; Humans; Kinetics; Mice; Models, Molecular; Mutation; Proline; Protein Aggregates; Protein Aggregation, Pathological; Protein Conformation; Protein Folding; Protein Multimerization; Protein Stability | 2017 |