Compounds > proline

proline and Parkinsonian Disorders

proline has been researched along with Parkinsonian Disorders in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Funayama, M; Hattori, N; Li, Y; Matsuura, E; Nishioka, K; Takanashi, M; Takashima, H; Tsuyama, S; Yoshino, H1
Barbe, MT; Coenen, HH; Fink, GR; Galldiks, N; Langen, KJ; Schroeter, M; Sommerauer, M; Stoffels, G; Timmermann, L; Willuweit, A1
Behari, M; Kirola, L; Shishir, C; Thelma, BK1
Cui, AM; Davenport, B; Garruto, RM; Go, RC; Heizer, JW; Hermosura, MC; Mocz, G; Perraud, AL; Schmitz, C; Shetler, CM1
Baekelandt, V; García-Horsman, JA; Gerard, M; Hannula, MJ; Lambeir, AM; Männistö, PT; Myöhänen, TT; Van Der Veken, P; Van Elzen, R1
Abramsky, O; Biran, I; Boher, M; Ekstein, D; Gal, A; Gomori, JM; Lossos, A; Meiner, Z; Newman, JP; Reches, A; Rosenmann, H; Soffer, D1
Epplen, JT; Krüger, R; Kuhn, W; Leenders, KL; Maguire, RP; Müller, T; Portman, AT; Przuntek, H; Riess, O; Schöls, L; Schröder, U; Sprengelmeyer, R; Veenma, L; Woitalla, D1

Trials

1 trial(s) available for proline and Parkinsonian Disorders

ArticleYear
Cis-4-[18F]fluoro-D-proline detects neurodegeneration in patients with akinetic-rigid parkinsonism.
    Nuclear medicine communications, 2019, Volume: 40, Issue:4

    Topics: Aged; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Parkinsonian Disorders; Positron-Emission Tomography; Proline

2019

Other Studies

6 other study(ies) available for proline and Parkinsonian Disorders

ArticleYear
Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations.
    Acta neuropathologica communications, 2018, 10-17, Volume: 6, Issue:1

    Topics: Aged; alpha-Synuclein; Astrocytes; Autopsy; DNA-Binding Proteins; Female; Gene Expression Regulation; Histidine; Homozygote; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Parkinsonian Disorders; Proline; Protein Aggregation, Pathological; Substantia Nigra; tau Proteins

2018
Identification of a novel homozygous mutation Arg459Pro in SYNJ1 gene of an Indian family with autosomal recessive juvenile Parkinsonism.
    Parkinsonism & related disorders, 2016, Volume: 31

    Topics: Adult; Arginine; DNA Mutational Analysis; Family Health; Female; Genes, Recessive; Humans; India; Magnetic Resonance Imaging; Male; Mutation; Parkinsonian Disorders; Phenotype; Phosphoric Monoester Hydrolases; Proline; Young Adult

2016
Altered functional properties of a TRPM2 variant in Guamanian ALS and PD.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Nov-18, Volume: 105, Issue:46

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Calcium; Calcium Signaling; Cell Membrane; Conserved Sequence; Cyanobacteria Toxins; Evolution, Molecular; Guam; Humans; Hydrogen Peroxide; Ion Channel Gating; Leucine; Magnesium; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Mutation; Oxidative Stress; Parkinsonian Disorders; Proline; Temperature; TRPM Cation Channels

2008
A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.
    British journal of pharmacology, 2012, Volume: 166, Issue:3

    Topics: alpha-Synuclein; Animals; Blotting, Western; Brain; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Motor Activity; Oxidative Stress; Parkinsonian Disorders; Proline; Prolyl Oligopeptidases; Reverse Transcriptase Polymerase Chain Reaction; Serine Endopeptidases; Serine Proteinase Inhibitors; Transfection

2012
Frontotemporal dementia and parkinsonism with the P301S tau gene mutation in a Jewish family.
    Journal of neurology, 2003, Volume: 250, Issue:6

    Topics: Adult; Algeria; Cerebral Cortex; Dementia; DNA Mutational Analysis; Family Health; Female; Humans; Immunohistochemistry; Inclusion Bodies; Jews; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neurologic Examination; Neuropsychological Tests; Parkinsonian Disorders; Pedigree; Proline; Serine; tau Proteins; Tomography, Emission-Computed, Single-Photon

2003
Familial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers.
    Neurology, 2001, May-22, Volume: 56, Issue:10

    Topics: Aged; Alanine; alpha-Synuclein; Amino Acid Sequence; Apolipoproteins E; Brain; DNA Mutational Analysis; Female; Genotype; Germany; Humans; Male; Middle Aged; Mutation; Nerve Tissue Proteins; Neuropsychological Tests; Parkinsonian Disorders; Pedigree; Proline; Synucleins; Thiolester Hydrolases; Tomography, Emission-Computed; Ubiquitin Thiolesterase

2001