Compounds > proline

proline and Obesity

proline has been researched along with Obesity in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.33)18.7374
1990's5 (11.63)18.2507
2000's26 (60.47)29.6817
2010's7 (16.28)24.3611
2020's4 (9.30)2.80

Authors

AuthorsStudies
Abd-Elhamied, MA; Abdelhaleem, IA; Kenawy, S; Morsi, AE1
Kang, S; Kim, HR; Kim, JH; Kim, TW; Lee, AR; Lee, E; Lee, JE1
Feng, S; Fu, Y; Gao, P; Hussein, A; Jiang, Q; Lang, L; Li, F; Liang, S; Ling, M; Ma, Z; Quan, LL; Shu, G; Wang, J; Wang, L; Wang, S; Wu, R; Xi, Q; Yang, X; Yi, X; Yin, C; Zhang, F; Zhang, L; Zhang, Y; Zhao, W; Zhu, C; Zhu, X1
Chen, Y; Dong, X; Fu, C; Jiang, Q; Wang, N; Zhu, J1
Angayarkanni, N; Radhakrishnan, S; Srinivasan, V; Sulochana, KN1
Fang, M; Gao, H; Liu, J; Liu, L; Ouyang, Y; Wang, X1
Iwasaki, M; Miyazaki, H; Nakamura, K; Sugita, N; Wang, Y; Yoshie, H; Yoshihara, A1
Danielsson, P; Johansson, LE; Marcus, C; Norgren, S; Ridderstråle, M1
Dong, CP; He, L; He, M; Li, JN; Wang, Y; Ye, F1
Akrami, SM; Amiri, P; Doosti, M; Golmohammadi, T; Heshmat, R; Mirzaei, H; Nakhjavani, M1
Ben Ali, S; Ben Yahia, F; Elasmi, M; Feki, M; Ftouhi, B; Haj-Taieb, S; Jemaa, R; Kaabachi, N; Kallel, A; Sanhagi, H; Sediri, Y; Slimane, H; Souheil, O1
Brown, JA; Chen, H; Chiang, P; Coffey, SB; Cornelius, P; Dombroski, MA; Gibbons, CP; Giragossian, C; Kong, JX; Lee, E; Lefker, BA; Liu, KK; Marala, R; Patterson, TA; Santucci, S; Tomlinson, E; Wenzel, Z; Werner, W; Zeng, Y1
Chen, CH; Chen, PY; Chiu, CC; Huang, MC; Kao, CF; Kuo, PH; Lu, ML1
Cseh, K; Jermendy, A; Körner, A; Kovács, M; Madácsy, L1
Canizales-Quinteros, S; Fernández, J; Hinojosa-Cruz, JC; López-Alarcón, M; Rodríguez-Cruz, M; Vital-Reyes, VS; Zavala-Ortega, MI1
Fernández-Real, JM; Fontova, R; Gallart, L; Gutiérrez, C; Richart, C; Simón, I; Vendrell, I; Vendrell, J1
Corella, D; González, JI; Portolés, O; Ramírez, JB; Ruiz de la Fuente, S; Sorlí, JV1
Masud, S; Ye, S1
Franco, LJ; Kasamatsu, TS; Matioli, SR; Moisés, RS; Reis, AF; Tavares, EF; Vieira-Filho, JP1
Chi, Y; Wang, C; Wang, G; Zhai, F1
Aertgeerts, K; Hilgers, M; Hosfield, DJ; Jennings, A; Skene, RJ; Snell, GP; Wu, Y1
Bidzińska, B; Demissie, M; Dobosz, T; Milewicz, A; Slezak, R; Tworowska, U2
Alemanno, I; Buzzetti, R; Caiazzo, AM; Capizzi, M; di Mario, U; Mein, CA; Osborn, JA; Petrone, A; Vania, A; Zavarella, S1
Charles, MA; Charpentier, G; Clément, K; Froguel, P; Ghoussaini, M; Lobbens, S; Meyre, D; Tauber, M; Weill, J1
Christodoulides, C; Dalla Nora, E; De Pergola, G; Farooqi, IS; Federspil, G; Granzotto, M; Keogh, J; Milan, G; O'Rahilly, S; Pannacciulli, N; Scarda, A; Sethi, JK; Stirling, H; Vettor, R; Vidal-Puig, A1
Ciechanowicz, A; Frankow, M; Majkowska, L; Moleda, P; Parczewski, M; Pilarska, K; Safranow, K; Stefański, A1
Agostoni, C; Biondi, ML; Giovannini, M; Radaelli, G; Salvioni, M; Scaglioni, S; Verduci, E1
Andersen, MK; Andreasen, CH; Borch-Johnsen, K; Eiberg, H; Hansen, L; Hansen, T; Jensen, DP; Jørgensen, T; Pedersen, O1
Altshuler, D; Delahanty, L; Florez, JC; Franks, PW; Hanson, RL; Jablonski, KA; Kahn, SE; Knowler, WC1
Iida, M; Ishida, K; Kuwajima, M; Mizuno, A; Murakami, T; Shima, K1
Andersen, RE; Andres, R; Beamer, BA; Cheskin, LJ; Elahi, D; Muller, D; Roth, J; Shuldiner, AR; Yen, CJ1
Dekker, JM; Hart, LM; Karvonen, MK; Koulu, M; Laakso, M; Niskanen, L; Pesonen, U; Rissanen, A; Uusitupa, MI; Valve, R1
Distler, A; Engeli, S; Ringel, J; Sharma, AM1
Deninger, M; Haist, K; Häring, HU; Koch, M; Maerker, E; Renn, W; Rett, K; Volk, A1
Chung, JH; Kim, KW; Lee, MK; Lee, MS; Min, KM; Min, YK; Oh, EY1
Andersen, RE; Beamer, BA; Brancati, FL; Kao, WH; Nguyen, W; Pratley, R; Shuldiner, AR1
Elbein, SC; Hasstedt, SJ; Ren, QF; Teng, K1
Beilby, JP; Chapman, CM; Hung, J; McQuillan, BM; Swarbrick, MM; Thompson, PL1
Chen, YD; Chuang, LM; Cox, D; Ho, LT; Hsiung, CA; Lei, HH; Nakatsuka, CH; Pei, D; Pratt, RE; Sheu, WH; Tai, TY1
Bendlová, B; Hainer, V; Hill, M; Kunesová, M; Srámková, D; Vcelák, J1
Bertilsson, L; Ding, B; Wahlestedt, C1
Gylfe, E1

Reviews

2 review(s) available for proline and Obesity

ArticleYear
Efficacy and safety of efpeglenatide in adults with obesity and its associated metabolic disturbance: A systematic review and meta-analysis of randomized controlled trials.
    Diabetes, obesity & metabolism, 2022, Volume: 24, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Obesity; Proline; Randomized Controlled Trials as Topic

2022
Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis.
    Journal of medical genetics, 2003, Volume: 40, Issue:10

    Topics: Alanine; Body Mass Index; Cohort Studies; Coronary Artery Disease; Female; Genotype; Humans; Male; Obesity; Polymorphism, Single Nucleotide; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; United Kingdom

2003

Trials

2 trial(s) available for proline and Obesity

ArticleYear
The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obesity-related traits in the Diabetes Prevention Program.
    Diabetologia, 2007, Volume: 50, Issue:12

    Topics: Adult; Alanine; Amino Acid Substitution; Body Composition; Chromans; Diabetes Mellitus, Type 2; Dietary Fats; Eating; Female; Gene Frequency; Genotype; Humans; Hypoglycemic Agents; Life Style; Male; Metformin; Middle Aged; Obesity; Placebos; PPAR gamma; Proline; Thiazolidinediones; Troglitazone

2007
Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels.
    Nature medicine, 1998, Volume: 4, Issue:12

    Topics: Adult; Aged; Alleles; Amino Acid Substitution; Cholesterol; Cholesterol, LDL; Female; Gene Frequency; Genotype; Humans; Leucine; Male; Middle Aged; Neuropeptide Y; Obesity; Polymorphism, Genetic; Proline; Protein Sorting Signals

1998

Other Studies

39 other study(ies) available for proline and Obesity

ArticleYear
Stachydrine derived from fermented rice prevents diet-induced obesity by regulating adipsin and endoplasmic reticulum homeostasis.
    The Journal of nutritional biochemistry, 2022, Volume: 107

    Topics: 3T3-L1 Cells; Animals; Complement Factor D; Diet, High-Fat; Endoplasmic Reticulum; Homeostasis; Insulin Resistance; Mice; Mice, Inbred C57BL; Obesity; Oryza; Proline

2022
Proline hydroxylase 2 (PHD2) promotes brown adipose thermogenesis by enhancing the hydroxylation of UCP1.
    Molecular metabolism, 2023, Volume: 73

    Topics: Adipose Tissue, Brown; Animals; Hydroxylation; Mice; Obesity; Proline; Prolyl Hydroxylases; Thermogenesis

2023
Associations between serum amino acids and incident type 2 diabetes in Chinese rural adults.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2021, 07-22, Volume: 31, Issue:8

    Topics: Adult; Biomarkers; Body Mass Index; China; Comorbidity; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Obesity; Proline; Prospective Studies; Risk Assessment; Risk Factors; Rural Health

2021
Antidiabetic effect of free amino acids supplementation in human visceral adipocytes through adiponectin-dependent mechanism.
    The Indian journal of medical research, 2019, Volume: 149, Issue:1

    Topics: Adipocytes; Adiponectin; Amino Acids; AMP-Activated Protein Kinase Kinases; Cells, Cultured; Diabetes Mellitus; Dietary Supplements; Gene Expression Regulation; Glucose; Humans; Hypoglycemic Agents; Intra-Abdominal Fat; Obesity; Phenylalanine; Proline; Protein Kinases; RNA, Messenger; RNA, Small Interfering; Signal Transduction

2019
The association between the Pro12Ala variant in the PPARγ2 gene and type 2 diabetes mellitus and obesity in a Chinese population.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Blood Glucose; Body Mass Index; China; Diabetes Mellitus, Type 2; Fasting; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Insulin; Male; Middle Aged; Obesity; Odds Ratio; Polymorphism, Genetic; PPAR gamma; Proline

2013
The Interaction Between β-3 Adrenergic Receptor and Peroxisome Proliferator-Activated Receptor Gamma Gene Polymorphism to Periodontal Disease in Community-Dwelling Elderly Japanese.
    Journal of periodontology, 2015, Volume: 86, Issue:8

    Topics: Aged; Alanine; Arginine; Body Mass Index; C-Reactive Protein; Epistasis, Genetic; Female; Gene-Environment Interaction; Genotype; Glycated Hemoglobin; Heterozygote; Humans; Middle Aged; Obesity; Periodontal Attachment Loss; Periodontal Diseases; Periodontal Index; Periodontal Pocket; Polymorphism, Genetic; Postmenopause; PPAR gamma; Proline; Receptors, Adrenergic, beta-3; Tooth Loss; Tryptophan

2015
Interaction between PPARG Pro12Ala and ADIPOQ G276T concerning cholesterol levels in childhood obesity.
    International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity, 2009, Volume: 4, Issue:2

    Topics: Adiponectin; Adolescent; Alanine; Body Mass Index; Child; Cholesterol; Cross-Sectional Studies; Female; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Homozygote; Humans; Insulin Resistance; Lipids; Male; Obesity; Polymorphism, Genetic; PPAR gamma; Proline; Risk Assessment; Risk Factors

2009
[Association of the Pro12Ala and C1431T polymorphism of the PPAR gamma2 gene and their haplotypes with obesity and type 2 diabetes].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2008, Volume: 25, Issue:4

    Topics: Alanine; Amino Acid Substitution; Asian People; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Haplotypes; Humans; Male; Middle Aged; Obesity; Polymorphism, Genetic; PPAR gamma; Proline; Triglycerides

2008
Polymorphism of Pro12Ala in the peroxisome proliferator-activated receptor gamma2 gene in Iranian diabetic and obese subjects.
    Metabolic syndrome and related disorders, 2009, Volume: 7, Issue:5

    Topics: Alanine; Asian People; Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Iran; Logistic Models; Male; Obesity; Odds Ratio; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Risk Assessment; Risk Factors

2009
Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-2 gene on obesity risk and leptin levels in a Tunisian population.
    Clinical biochemistry, 2009, Volume: 42, Issue:16-17

    Topics: Alanine; Case-Control Studies; Female; Humans; Leptin; Male; Obesity; PPAR gamma; Proline; Risk Factors; Sex Factors; Tunisia

2009
Orally active and brain permeable proline amides as highly selective 5HT2c agonists for the treatment of obesity.
    Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

    Topics: Administration, Oral; Amides; Animals; Anti-Obesity Agents; Brain; Dogs; Eating; Humans; Obesity; Proline; Rats; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Structure-Activity Relationship

2010
Gender differences in the effects of peroxisome proliferator-activated receptor γ2 gene polymorphisms on metabolic adversity in patients with schizophrenia or schizoaffective disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1

    Topics: Adult; Alanine; Female; Gene Frequency; Genotype; Humans; Male; Metabolic Diseases; Metabolic Syndrome; Middle Aged; Obesity; Polymorphism, Genetic; PPAR gamma; Proline; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Sex Characteristics

2011
PPAR-gamma2 pro12Ala polymorphism is associated with post-challenge abnormalities of glucose homeostasis in children and adolescents with obesity.
    Journal of pediatric endocrinology & metabolism : JPEM, 2011, Volume: 24, Issue:1-2

    Topics: Adolescent; Alanine; Amino Acid Substitution; Child; Cohort Studies; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Glucose; Glucose Metabolism Disorders; Glucose Tolerance Test; Homeostasis; Humans; Male; Obesity; Polymorphism, Single Nucleotide; PPAR gamma; Proline

2011
PPARγ2 Pro12Ala polymorphism is associated with improved lipoprotein lipase functioning in adipose tissue of insulin resistant obese women.
    Gene, 2012, Dec-15, Volume: 511, Issue:2

    Topics: Adipose Tissue; Adult; Alanine; Base Sequence; DNA Primers; Female; Humans; Insulin Resistance; Lipoprotein Lipase; Middle Aged; Obesity; Polymerase Chain Reaction; PPAR gamma; Proline

2012
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma is associated with increased leptin levels in women with type-2 diabetes mellitus.
    Hormone research, 2002, Volume: 58, Issue:3

    Topics: Aged; Alanine; Alleles; Antigens, CD; Body Mass Index; Cytokines; Diabetes Mellitus, Type 2; Female; Gene Frequency; Heterozygote; Humans; Leptin; Linear Models; Male; Middle Aged; Mutation; Obesity; Proline; Receptors, Cytoplasmic and Nuclear; Receptors, Leptin; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Sex Characteristics; Transcription Factors

2002
[Low prevalence of the Leu7/Pro polymorphism in the signal peptide of preproneuropeptide Y in the Spanish Mediterranean population].
    Medicina clinica, 2003, Mar-15, Volume: 120, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cross-Sectional Studies; Female; Humans; Leucine; Lipids; Male; Middle Aged; Neuropeptide Y; Obesity; Polymorphism, Genetic; Prevalence; Proline; Protein Precursors; Spain

2003
Influence of the polymorphisms Tpr64Arg in the beta 3-adrenergic receptor gene and Pro12Ala in the PPAR gamma 2 gene on metabolic syndrome-related phenotypes in an indigenous population of the Brazilian Amazon.
    Diabetes care, 2004, Volume: 27, Issue:2

    Topics: Alanine; Arginine; Brazil; Female; Humans; Male; Metabolic Syndrome; Obesity; Phenotype; Polymorphism, Single Nucleotide; Proline; Racial Groups; Receptors, Adrenergic, beta-3; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan

2004
[Association of Pro12Ala mutation in peroxisome proliferator-activated receptor gamma 2 with obesity and diabetes in Chinese population].
    Wei sheng yan jiu = Journal of hygiene research, 2004, Volume: 33, Issue:3

    Topics: Adult; Alanine; Diabetes Mellitus; Female; Gene Frequency; Humans; Male; Mutation; Obesity; Polymorphism, Restriction Fragment Length; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2004
Conformational flexibility in crystal structures of human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation.
    The Journal of biological chemistry, 2005, Feb-11, Volume: 280, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Amino Acid Motifs; Binding Sites; Cloning, Molecular; Cortisone; Crystallography, X-Ray; Cysteine; Diabetes Mellitus, Type 2; Dimerization; Disulfides; Endoplasmic Reticulum; Enzyme Inhibitors; Escherichia coli; Glucocorticoids; Humans; Hydrocortisone; Kinetics; Mass Spectrometry; Models, Molecular; Mutagenesis; Obesity; Oxygen; Point Mutation; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins

2005
[Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in PPARgamma gene?].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 16, Issue:95

    Topics: Alanine; Case-Control Studies; Female; Glutamine; Heterozygote; Homozygote; Humans; Male; Obesity; Poland; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline; Sex Factors

2004
PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity.
    Pediatric research, 2005, Volume: 57, Issue:1

    Topics: Adolescent; Alanine; Child; Exons; Female; Genetic Variation; Genotype; Humans; Insulin; Insulin Resistance; Italy; Linear Models; Male; Mutation, Missense; Obesity; Phenotype; Polymorphism, Genetic; PPAR gamma; Proline; Risk Factors

2005
[Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in the PPARgamma gene?].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 17, Issue:100

    Topics: Alanine; Body Mass Index; Case-Control Studies; Female; Gene Frequency; Glycine; Humans; Male; Obesity; Poland; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline

2004
Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.
    BMC medical genetics, 2005, Mar-22, Volume: 6

    Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Case-Control Studies; Child; Diabetes Mellitus, Type 2; Female; France; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Single Nucleotide; PPAR gamma; Proline; White People

2005
WNT10B mutations in human obesity.
    Diabetologia, 2006, Volume: 49, Issue:4

    Topics: Adipocytes; Adult; Amino Acid Sequence; Animals; Cell Differentiation; Cell Line; Conserved Sequence; Cysteine; DNA Mutational Analysis; Female; Humans; Male; Mice; Molecular Sequence Data; Mutation; Obesity; Pedigree; Proline; Proto-Oncogene Proteins; Sequence Alignment; Signal Transduction; Wnt Proteins

2006
Association between the Pro12Ala variant of the peroxisome proliferator-activated receptor-gamma2 gene and increased 24-h diastolic blood pressure in obese patients with type II diabetes.
    Journal of human hypertension, 2006, Volume: 20, Issue:9

    Topics: Alanine; Alleles; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Polymorphism, Genetic; PPAR gamma; Proline; Time Factors

2006
PPAR-gamma2 Pro12Ala variant, insulin resistance and plasma long-chain polyunsaturated fatty acids in childhood obesity.
    Pediatric research, 2006, Volume: 60, Issue:4

    Topics: Alanine; Child; Fatty Acids, Unsaturated; Female; Gene Frequency; Humans; Insulin Resistance; Male; Obesity; Phospholipids; Polymorphism, Genetic; PPAR gamma; Proline

2006
The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:5

    Topics: Adult; Amidohydrolases; Body Mass Index; Case-Control Studies; Cohort Studies; Denmark; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Mutation; Obesity; Phenotype; Population Surveillance; Proline; Threonine; White People

2007
Substitution at codon 269 (glutamine --> proline) of the leptin receptor (OB-R) cDNA is the only mutation found in the Zucker fatty (fa/fa) rat.
    Biochemical and biophysical research communications, 1996, Jul-16, Volume: 224, Issue:2

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Brain; Carrier Proteins; Cloning, Molecular; Codon; DNA Primers; DNA, Complementary; Genetic Variation; Glutamine; Humans; Male; Mice; Molecular Sequence Data; Obesity; Organ Specificity; Point Mutation; Polymerase Chain Reaction; Proline; Rats; Rats, Sprague-Dawley; Rats, Wistar; Rats, Zucker; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic

1996
Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations.
    Diabetes, 1998, Volume: 47, Issue:11

    Topics: Adipose Tissue; Animals; Cohort Studies; Humans; Mice; Muscle, Skeletal; Mutation; Obesity; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proline; Prospective Studies; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors

1998
Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus.
    Biochemical and biophysical research communications, 1999, Jan-19, Volume: 254, Issue:2

    Topics: Adult; Alanine; Amino Acid Substitution; Cholesterol; Codon; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Female; Gene Frequency; Genetic Variation; Humans; Hyperlipidemias; Male; Middle Aged; Mutation, Missense; Nuclear Proteins; Obesity; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Triglycerides

1999
The PPARgamma2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects.
    Diabetologia, 1999, Volume: 42, Issue:6

    Topics: Adult; Alanine; Amino Acid Substitution; Codon; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Male; Mutation; Obesity; Polymorphism, Genetic; Proline; Quantitative Trait, Heritable; Receptors, Cytoplasmic and Nuclear; Transcription Factors

1999
Significance of Pro12Ala mutation in peroxisome proliferator-activated receptor-gamma2 in Korean diabetic and obese subjects.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:5

    Topics: Alanine; Amino Acid Substitution; Asian People; Body Mass Index; Diabetes Mellitus; Female; Genotype; Glucose Intolerance; Humans; Korea; Male; Middle Aged; Nuclear Proteins; Obesity; Point Mutation; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2000
Pro115Gln peroxisome proliferator-activated receptor-gamma and obesity.
    Diabetes care, 2000, Volume: 23, Issue:1

    Topics: Adult; Amino Acid Substitution; Black People; Female; Glutamine; Humans; Indians, North American; Male; Middle Aged; Nuclear Proteins; Obesity; Point Mutation; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; United States; White People

2000
Effect of the peroxisome proliferator-activated receptor-gamma 2 pro(12)ala variant on obesity, glucose homeostasis, and blood pressure in members of familial type 2 diabetic kindreds.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:2

    Topics: Alanine; Amino Acid Substitution; Blood Glucose; Blood Pressure; Body Mass Index; Chromosomes, Human, Pair 3; Diabetes Mellitus; Diabetes Mellitus, Type 2; Family; Gene Frequency; Genetic Variation; Glucose Tolerance Test; Humans; Leptin; Microbodies; Middle Aged; Nuclear Family; Obesity; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors; White People

2001
A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity.
    European journal of endocrinology, 2001, Volume: 144, Issue:3

    Topics: Aging; Alanine; Alleles; Amino Acid Substitution; Anthropometry; Australia; Blood Pressure; Cholesterol, HDL; Diabetes Mellitus; Female; Genetic Predisposition to Disease; Genotype; Humans; Hyperlipidemias; Male; Middle Aged; Obesity; Odds Ratio; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Sex Characteristics; Smoking; Thinness; Transcription Factors; Triglycerides; White People

2001
Sibling-based association study of the PPARgamma2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families: a SAPPHIRe study. Stanford Asian-Pacific Program in Hypertension and Insulin Resistance.
    Journal of molecular medicine (Berlin, Germany), 2001, Volume: 79, Issue:11

    Topics: Adult; Age Factors; Aged; Alanine; Alleles; Blood Glucose; China; Family Health; Female; Genotype; Glucose Tolerance Test; Homozygote; Humans; Hypertension; Insulin Resistance; Japan; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Regression Analysis; Sex Factors; Time Factors; Transcription Factors

2001
Is a Pro12Ala polymorphism of the PPARgamma2 gene related to obesity and type 2 diabetes mellitus in the Czech population?
    Annals of the New York Academy of Sciences, 2002, Volume: 967

    Topics: Adult; Alanine; Case-Control Studies; Czechoslovakia; Diabetes Mellitus, Type 2; Female; Genetics, Population; Genotype; Humans; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2002
The single nucleotide polymorphism T1128C in the signal peptide of neuropeptide Y (NPY) was not identified in a Korean population.
    Journal of clinical pharmacy and therapeutics, 2002, Volume: 27, Issue:3

    Topics: Adult; Base Sequence; Genetics, Population; Genotype; Humans; Korea; Leucine; Neuropeptide Y; Obesity; Polymorphism, Single Nucleotide; Proline; Protein Sorting Signals

2002
Changes of free amino acids in pancreatic beta-cells after starvation and substrate deprivation.
    Acta endocrinologica, 1974, Volume: 75, Issue:1

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography, Thin Layer; Dansyl Compounds; Diabetes Mellitus; Fasting; Female; Freeze Drying; Glutamates; Glycine; Islets of Langerhans; Leucine; Lysine; Mice; Obesity; Ornithine; Phenylalanine; Proline; Taurine; Tritium; Valine

1974