Compounds > proline

proline and Methemoglobinemia

proline has been researched along with Methemoglobinemia in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barber, MJ; Bewley, MC; Davis, CA; Marohnic, CC; Taormina, D1
Irken, G; Oren, H; Percy, MJ; Savage, G1
Nagai, T; Shirabe, K; Takeshita, M; Yubisui, T1
Fukumaki, Y; Inoue, J; Kobayashi, Y; Sakaki, Y; Yubisui, T1

Other Studies

4 other study(ies) available for proline and Methemoglobinemia

ArticleYear
The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site.
    Biochemistry, 2003, Nov-18, Volume: 42, Issue:45

    Topics: Adenosine Monophosphate; Amino Acid Substitution; Animals; Binding Sites; Crystallography, X-Ray; Cytochrome-B(5) Reductase; Flavin-Adenine Dinucleotide; Humans; Kinetics; Methemoglobinemia; Mutagenesis, Site-Directed; NAD; Proline; Protein Conformation; Rats; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Substrate Specificity

2003
Congenital methaemoglobinaemia Type I in a Turkish infant due to a novel mutation, Pro144Ser, in NADH-cytochrome b5 reductase.
    The hematology journal : the official journal of the European Haematology Association, 2004, Volume: 5, Issue:4

    Topics: Amino Acid Substitution; Ascorbic Acid; Cytochrome-B(5) Reductase; Female; Humans; Infant; Methemoglobinemia; Mutation, Missense; Proline; Serine; Treatment Outcome; Turkey

2004
Analysis of mutant NADH-cytochrome b5 reductase: apparent "type III" methemoglobinemia can be explained as type I with an unstable reductase.
    Blood, 1993, Feb-01, Volume: 81, Issue:3

    Topics: Adult; Amino Acid Sequence; Base Sequence; Blotting, Western; Cells, Cultured; Cytochrome Reductases; Cytochrome-B(5) Reductase; Enzyme Stability; Fibroblasts; Humans; Kinetics; Leucine; Male; Methemoglobinemia; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligodeoxyribonucleotides; Proline; Reference Values; Skin; Thermodynamics

1993
Serine-proline replacement at residue 127 of NADH-cytochrome b5 reductase causes hereditary methemoglobinemia, generalized type.
    Blood, 1990, Apr-01, Volume: 75, Issue:7

    Topics: Adult; Alleles; Amino Acid Sequence; Base Sequence; Blood Platelets; Cytochrome Reductases; Cytochrome-B(5) Reductase; Erythrocytes; Female; Genomic Library; Homozygote; Humans; Lymphocytes; Male; Methemoglobin; Methemoglobinemia; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Pedigree; Proline; Reference Values; Restriction Mapping; Serine

1990