proline and Lung Neoplasms

proline has been researched along with Lung Neoplasms in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (10.17)	18.7374
1990's	9 (15.25)	18.2507
2000's	24 (40.68)	29.6817
2010's	13 (22.03)	24.3611
2020's	7 (11.86)	2.80

Authors

Authors	Studies
Liang, L; Wang, X; Yin, W	1
Ma, X; Wei, Y; Yang, Z; Zhang, W; Zhou, F	1
Angel, PM; Ball, L; Bethard, J; Bruner, E; Clift, CL; Drake, RR; Feghali-Bostwick, C	1
Cao, Y; Chen, C; Liu, N; Liu, S; Liu, Y; Mao, C; Ouyang, L; Shi, Y; Tang, H; Tao, Y; Wang, M; Wang, X; Xiao, D; Yan, Q	1
Bao, R; Cui, C; Guo, L; Ran, J; Su, W; Wang, J; Wu, C; Yang, Q; Yuan, J; Zhang, P	1
He, X; Huang, X; Li, Y; Ma, K; Ma, X; Wang, C	1
Cui, C; Guo, L; Wang, J; Wu, C	1
Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW	1
Boon, R; Broekaert, D; Christen, S; Elia, I; Fendt, SM; Grünewald, TGP; Orth, MF; Radaelli, E; Verfaillie, C	1
Brooks, AJ; Chhabra, Y; Kragelund, BB; Meunier, FA; Nikolajsen, LF; Papadopulos, A; Smith, AG; Steinocher, H; Tunny, KA; Waters, MJ; Wong, HY	1
Chen, C; Feng, D; Wang, X; Ye, J; Yin, R; Zhang, S; Zhang, Z; Zhao, X; Zhou, G	1
Chang, Q; Li, YL; Zhao, X	1
Knezevic, CE; Kratz, LE; Marzinke, MA; Ness, MA	1
Chen, K; Cui, C; Guo, L; Lu, Y; Sun, Y; Tang, B; Wang, J; Wang, Y; Wu, C; Xiao, G; Yuan, J; Zhang, K	1
Dahabreh, IJ; Lau, J; Murray, S; Schmid, CH; Trikalinos, TA; Varvarigou, V	1
Lee, M; Venkitaraman, AR	1
Jee, SH; Lee, S; Pamungkas, AD; Park, C; Park, YH	1
Chen, X; Feng, H; Lu, JJ; Pei, L; Wang, Y	1
Chen, CY; Chen, WC; Fong, YC; Hsu, SF; Huang, CY; Kao, ST; Li, TM; Liu, SC; Tang, CH; Tsai, FJ	1
Li, Y; Lv, XJ; Qian, XP; Qiu, LX; Shen, XK; Song, Y	1
Gunduz, M; Mita, Y; Naomoto, Y; Ouchida, M; Sakai, A; Shimizu, K; Tanabe, S; Toyooka, S; Yamamoto, H; Yasuda, Y	1
Kumar, A; Kumar, S; Mathur, N; Pant, MC; Tilak, AR	1
Papadakis, ED; Soulitzis, N; Spandidos, DA	1
Harada, R; Kobayashi, M; Nakata, H; Taguchi, H; Uemura, Y	1
Oliver, J; Palou, A; Proenza, AM; Roca, P	1
LORINCZ, AB; RYAN, WL	1
POMEROY, LR; ROACH, MK; SIEGEL, FL	1
Anthwal, S; Arenberg, DA; Keshamouni, VG; Newstead, MJ; Reddy, RC; Standiford, TJ	1
Ahrendt, SA; Hu, Y; McDermott, MP	1
Kasprzak, KS; Salnikow, K	1
Borg, A; Dziadziuszko, R; Jassem, E; Jassem, J; Kobierska-Gulida, G; Limon, J; Rzyman, W; Szymanowska, A	1
Frederiksen, K; Hansen, RD; Overvad, K; Raaschou-Nielsen, O; Sørensen, M; Tjønneland, A; Vogel, U	1
Chen, MH; Cui, SX; Gai, R; Guo, Q; Makuuchi, M; Nakata, M; Qu, XJ; Tang, W; Tian, ZG; Xu, WF; Yuan, YX	1
Bartsch, H; Butkiewicz, D; Dienemann, H; Edler, L; Muley, T; Popanda, O; Risch, A; Schattenberg, T; Schmezer, P; Waas, P	1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Waheed Roomi, M	1
Bindokas, VP; Jagadeeswaran, R; Jagadeeswaran, S; Salgia, R	1
Bridle, H; Eisen, T; El Galta, R; Houlston, RS; Matakidou, A; Rudd, MF; Webb, EL	1
Aboul-Fadl, T; El-Sayed, WM; Franklin, MR; Moos, PJ; Roberts, JC	1
Buech, T; Chubanov, V; Grosse, R; Gudermann, T; Roelle, S	1
Andreassen, T; Ekstrøm, PO; Haugen, A; Lind, H; Ryberg, D; Skaug, V; Stangeland, L; Zienolddiny, S	1
Boldrini, L; Fontanini, G; Gisfredi, S; Greco, G; Lucchi, M; Mussi, A; Ursino, S	1
Cao, G; Feng, J; Hou, Y; Lu, H; Shu, J; Zheng, D	1
Andrlíková, J; Deyl, Z; Svojtková, E	1
Amos, CI; Branch, C; Honn, SE; Jin, X; King, TM; Roth, JA; Spitz, MR; Wu, X	1
An, G; Carlson, DM; Oreffo, V; Tesfaigzi, J; Wright, PS; Wu, R	1
McDonald, FJ; Welsh, MJ	1
Kimura, H; Kimura, M; Murata, M; Saisho, H; Tagawa, M; Watanabe, S	1
Levine, AJ; Walker, KK	1
Corbella, J; Estape, J; Firvida, J; Fuentes, M; Galan, C; Gene, M; Gomez-Catalan, J; Huguet, E; Rodamilans, M; To-Figueras, J	1
Bogdan, J; Chyczewski, L; Karna, E; Pałka, J; Słodkowska, J	1
Chyczewski, L; Karna, E; Miltyk, W; Pałka, J; Rudziński, P; Słodkowska, J; Worowski, K	1
Fujisawa, T; Kakisawa, K; Kimura, H; Murata, M; Shirasawa, H; Tagawa, M	1
Belinsky, SA; March, TH; Wardlaw, SA	1
Karna, E; Palka, J; Surazynski, A	1
Christiani, DC; Fan, R; Liu, G; Lynch, TJ; Miller, DP; Su, L; Thurston, SW; Wain, JC; Xu, LL; Zhou, W	1
Baptiste, N; Chen, X; Friedlander, P; Prives, C	1
Bills, DD; Nixon, JE; Scanlan, RA; Sinnhuber, RO; Wales, JH	1
Belloni, PN; Nakajima, M; Nicolson, GL; Welch, DR	1
Greenblatt, M; Lijinsky, W	1

Reviews

3 review(s) available for proline and Lung Neoplasms

Article	Year
Genotype misclassification in genetic association studies of the rs1042522 TP53 (Arg72Pro) polymorphism: a systematic review of studies of breast, lung, colorectal, ovarian, and endometrial cancer. American journal of epidemiology, 2013, Jun-15, Volume: 177, Issue:12 Topics: Alleles; Bayes Theorem; Breast Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Female; Genes, p53; Genotyping Techniques; Humans; Loss of Heterozygosity; Lung Neoplasms; Neoplasms; Ovarian Neoplasms; Polymorphism, Genetic; Proline	2013
A meta-analysis of TP53 codon 72 polymorphism and lung cancer risk: evidence from 15,857 subjects. Lung cancer (Amsterdam, Netherlands), 2009, Volume: 66, Issue:1 Topics: Asian People; Codon; Gene Frequency; Genes, p53; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Polymorphism, Single Nucleotide; Proline; Smoking; White People	2009
Ascorbate depletion: a critical step in nickel carcinogenesis? Environmental health perspectives, 2005, Volume: 113, Issue:5 Topics: Animals; Antioxidants; Ascorbic Acid; Cell Transformation, Neoplastic; DNA Damage; Homeostasis; Humans; Hydroxylation; Lung Neoplasms; Nickel; Proline; Protein Binding; Rats	2005

Other Studies

56 other study(ies) available for proline and Lung Neoplasms

Article	Year
PELP1 is overexpressed in lung cancer and promotes tumor cell malignancy and resistance to tyrosine kinase inhibitor drug. Pathology, research and practice, 2022, Volume: 237 Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Co-Repressor Proteins; CTLA-4 Antigen; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Glutamates; Humans; Leucine; Lung Neoplasms; Proline; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Transcription Factors	2022
Network Pharmacology and Bioinformatics Analysis Identifies Potential Therapeutic Targets of Paxlovid Against LUAD/COVID-19. Frontiers in endocrinology, 2022, Volume: 13 Topics: Adenocarcinoma of Lung; Computational Biology; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Humans; Interleukin-17; Interleukin-6; Lactams; Leucine; Lung Neoplasms; Molecular Docking Simulation; Network Pharmacology; Nitriles; Proline; Receptors, Cytokine; Ritonavir; SARS-CoV-2; United States	2022
Extracellular matrix alterations in low-grade lung adenocarcinoma compared with normal lung tissue by imaging mass spectrometry. Journal of mass spectrometry : JMS, 2020, Volume: 55, Issue:4 Topics: Adenocarcinoma of Lung; Adult; Area Under Curve; Chromatography, Liquid; Collagen; Extracellular Matrix; Female; Humans; Hydroxylation; Lung Neoplasms; Male; Matrix Metalloproteinase 13; Middle Aged; Proline; Proof of Concept Study; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Tissue Array Analysis; Tumor Microenvironment	2020
Cancer progression is mediated by proline catabolism in non-small cell lung cancer. Oncogene, 2020, Volume: 39, Issue:11 Topics: Animals; Carcinoma, Non-Small-Cell Lung; Disease Progression; Humans; Lung Neoplasms; Mice; Proline; Transfection	2020
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth. Nature communications, 2020, 10-01, Volume: 11, Issue:1 Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Animals; Cell Proliferation; Cytoskeletal Proteins; delta-1-Pyrroline-5-Carboxylate Reductase; Disease Models, Animal; Dynamins; Female; Gene Knockout Techniques; Humans; LIM Domain Proteins; Lung; Lung Neoplasms; Male; Membrane Proteins; Mice; Mice, Transgenic; Middle Aged; Mitochondria; Mitochondrial Dynamics; Muscle Proteins; Neoplasm Proteins; Proline; Proto-Oncogene Proteins p21(ras); Pyrroline Carboxylate Reductases; Survival Analysis	2020
Small extracellular ring domain is necessary for CD82/KAI1'anti-metastasis function. Biochemical and biophysical research communications, 2021, 06-11, Volume: 557 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Genes, Tumor Suppressor; Humans; Kangai-1 Protein; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Peptide Fragments; Proline; Protein Domains; Structure-Activity Relationship; Xenograft Model Antitumor Assays	2021
PINCH-1 promotes Δ Amino acids, 2021, Volume: 53, Issue:12 Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Humans; LIM Domain Proteins; Lung Neoplasms; Membrane Proteins; Mice; Mice, Transgenic; Proline; RNA, Messenger	2021
A Specific Mixture of Nutrients Suppresses Ovarian Cancer A-2780 Tumor Incidence, Growth, and Metastasis to Lungs. Nutrients, 2017, Mar-18, Volume: 9, Issue:3 Topics: Animals; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Lysine; Matrix Metalloproteinase 9; Mice; Mice, Nude; Micronutrients; Neoplasm Metastasis; Ovarian Neoplasms; Plant Extracts; Proline; Quercetin; Tea; Xenograft Model Antitumor Assays	2017
Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells. Nature communications, 2017, 05-11, Volume: 8 Topics: Adenosine Triphosphate; Aldehyde Dehydrogenase; Animals; Cell Culture Techniques; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; delta-1-Pyrroline-5-Carboxylate Reductase; Humans; Lung Neoplasms; Mice, Inbred C57BL; Proline; Proline Oxidase; Pyrroline Carboxylate Reductases; Spheroids, Cellular	2017
A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation. Oncogene, 2018, 01-25, Volume: 37, Issue:4 Topics: Animals; Carrier Proteins; Cell Line, Tumor; Cohort Studies; Computational Biology; Disease Progression; DNA Mutational Analysis; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lung; Lung Neoplasms; Magnetic Resonance Spectroscopy; Male; Mice; Phosphorylation; Polymorphism, Single Nucleotide; Proline; Protein Binding; Protein Domains; Proteolysis; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Threonine; Ubiquitin-Protein Ligases; Ubiquitination	2018
Sepia Ink Oligopeptide Induces Apoptosis of Lung Cancer Cells via Mitochondrial Pathway. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:5 Topics: A549 Cells; Animals; Apoptosis; bcl-2-Associated X Protein; Calpain; Caspase 12; Caspase 8; Caspase 9; Cell Proliferation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; fas Receptor; Humans; Ink; Leupeptins; Lung Neoplasms; Mitochondria; Oligopeptides; Proline; Proto-Oncogene Proteins c-bcl-2; Sepia; Thiocarbamates; Transcription Factor CHOP	2018
Total synthesis and cyclization strategy of samoamide A, a cytotoxic cyclic octapeptide rich in proline and phenlalanine isolated from marine cyanobacterium. Journal of Asian natural products research, 2019, Volume: 21, Issue:2 Topics: Antineoplastic Agents; Aquatic Organisms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyanobacteria; Humans; Lung Neoplasms; Molecular Structure; Peptides, Cyclic; Phenylalanine; Proline	2019
Elevated creatinine in a patient on IVIG-therapy. Clinica chimica acta; international journal of clinical chemistry, 2018, Volume: 486 Topics: Carcinoma, Non-Small-Cell Lung; Creatinine; Female; Humans; Immunoglobulins, Intravenous; Lung Neoplasms; Middle Aged; Paraneoplastic Syndromes; Proline	2018
Kindlin-2 links mechano-environment to proline synthesis and tumor growth. Nature communications, 2019, 02-19, Volume: 10, Issue:1 Topics: A549 Cells; Adenocarcinoma of Lung; Animals; Cell Proliferation; Cell Survival; Cytoskeletal Proteins; delta-1-Pyrroline-5-Carboxylate Reductase; Extracellular Matrix; Female; Humans; Lung Neoplasms; Male; Membrane Proteins; Mice, Transgenic; Mitochondria; Muscle Proteins; Neoplasm Proteins; Proline; Pyrroline Carboxylate Reductases	2019
A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis. Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:16 Topics: Alanine; BRCA2 Protein; Cytokinesis; DNA-Binding Proteins; HeLa Cells; High Mobility Group Proteins; Humans; Lung Neoplasms; Mutation; Proline	2014
High resolution metabolomics to discriminate compounds in serum of male lung cancer patients in South Korea. Respiratory research, 2016, 08-09, Volume: 17, Issue:1 Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Chromatography, Liquid; Cluster Analysis; Humans; Lung Neoplasms; Male; Metabolomics; Middle Aged; Predictive Value of Tests; Proline; Republic of Korea; Risk Factors; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Vitamin A	2016
Osthole inhibited TGF β-induced epithelial-mesenchymal transition (EMT) by suppressing NF-κB mediated Snail activation in lung cancer A549 cells. Cell adhesion & migration, 2017, Sep-03, Volume: 11, Issue:5-6 Topics: A549 Cells; Cadherins; Coumarins; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; NF-kappa B; Proline; Snail Family Transcription Factors; Thiocarbamates; Transcription Factor RelA; Transforming Growth Factor beta	2017
Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway. Lung cancer (Amsterdam, Netherlands), 2009, Volume: 64, Issue:3 Topics: Adenocarcinoma; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Cell Movement; Chromones; Flavonoids; Focal Adhesion Kinase 1; Humans; Integrin alphaVbeta3; Lung Neoplasms; Morpholines; NF-kappa B; Oncogene Protein v-akt; Osteopontin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proline; Signal Transduction; Thiocarbamates; Tosylphenylalanyl Chloromethyl Ketone	2009
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers. Journal of cancer research and clinical oncology, 2010, Volume: 136, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Esophageal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Incidence; Isoleucine; Japan; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Single Nucleotide; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Risk Factors	2010
Polymorphism Arg72Pro of p53 confers susceptibility to squamous cell carcinoma of lungs in a North Indian population. DNA and cell biology, 2013, Volume: 32, Issue:2 Topics: Aged; Amino Acid Substitution; Arginine; Asian People; Carcinoma, Squamous Cell; Case-Control Studies; Female; Genes, p53; Genetic Predisposition to Disease; Genetics, Population; Genotype; Humans; India; Lung Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Proline	2013
Association of p53 codon 72 polymorphism with advanced lung cancer: the Arg allele is preferentially retained in tumours arising in Arg/Pro germline heterozygotes. British journal of cancer, 2002, Oct-21, Volume: 87, Issue:9 Topics: Aged; Arginine; Bronchoalveolar Lavage Fluid; Codon; DNA Primers; Female; Gene Deletion; Genes, p53; Genotype; Germ-Line Mutation; Heterozygote; Humans; Loss of Heterozygosity; Lung Neoplasms; Male; Middle Aged; Papillomaviridae; Papillomavirus Infections; Polymorphism, Genetic; Proline; Sputum; Tumor Suppressor Protein p53; Tumor Virus Infections	2002
Cyclooxygenase-2 inhibitor NS-398 suppresses cell growth and constitutive production of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells. Cancer science, 2003, Volume: 94, Issue:2 Topics: Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Progression; Drug Screening Assays, Antitumor; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-1; Isoenzymes; Lung Neoplasms; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Proteins; NF-kappa B; Nitrobenzenes; Proline; Prostaglandin-Endoperoxide Synthases; Pyridines; Recombinant Proteins; Sulfonamides; Thiocarbamates; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2003
Breast and lung cancer are associated with a decrease in blood cell amino acid content. The Journal of nutritional biochemistry, 2003, Volume: 14, Issue:3 Topics: Adult; Aged; Amino Acids; Amino Acids, Essential; Asparagine; Blood Cells; Breast Neoplasms; Female; Glutamic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Ornithine; Plasma; Proline; Valine	2003
FREE AMINO ACIDS OF HUMAN BREAST CANCER. The Nebraska state medical journal, 1964, Volume: 49 Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine	1964
MULTIPLE DISCRIMINANT ANALYSIS OF PLASMA AMINO ACID PATTERNS. Proceedings of the National Academy of Sciences of the United States of America, 1964, Volume: 51 Topics: Adenocarcinoma; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Blood Chemical Analysis; Carcinoma, Bronchogenic; Computers; Diagnosis, Differential; Discriminant Analysis; Ethanol; Fasting; Humans; Lung Neoplasms; Prognosis; Proline; Proteins; Research; Schizophrenia; Tuberculosis; Tuberculosis, Pulmonary	1964
PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer. Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:3 Topics: Amino Acid Motifs; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chemokine CXCL1; Chemokine CXCL11; Chemokine CXCL5; Chemokines, CXC; Chemotaxis; Chromans; Culture Media, Conditioned; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Factor VIII; Humans; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Interleukin-8; Ligands; Lung Neoplasms; Mice; Mice, SCID; Microcirculation; Neoplasm Transplantation; Neovascularization, Pathologic; NF-kappa B; Pioglitazone; PPAR gamma; Proline; Thiazolidinediones; Thiocarbamates; Transfection; Troglitazone	2005
The p53 codon 72 proline allele is associated with p53 gene mutations in non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Apr-01, Volume: 11, Issue:7 Topics: Aged; Alleles; Arginine; Carcinoma, Non-Small-Cell Lung; Codon; Female; Gene Frequency; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Mutation; Polymorphism, Genetic; Proline; Regression Analysis; Survival Analysis; Tumor Suppressor Protein p53	2005
Increased risk of non-small cell lung cancer and frequency of somatic TP53 gene mutations in Pro72 carriers of TP53 Arg72Pro polymorphism. Lung cancer (Amsterdam, Netherlands), 2006, Volume: 52, Issue:1 Topics: Adenocarcinoma; Arginine; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Genetic Predisposition to Disease; Genotype; Heterozygote; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Polymorphism, Genetic; Proline; Risk Factors; Tumor Suppressor Protein p53	2006
GPX1 Pro198Leu polymorphism, interactions with smoking and alcohol consumption, and risk for lung cancer. Cancer letters, 2007, Mar-18, Volume: 247, Issue:2 Topics: Alcohol Drinking; Cohort Studies; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Leucine; Lung Neoplasms; Middle Aged; Polymorphism, Genetic; Proline; Risk Factors; Smoking	2007
Using caffeoyl pyrrolidine derivative LY52, a potential inhibitor of matrix metalloproteinase-2, to suppress tumor invasion and metastasis. International journal of molecular medicine, 2006, Volume: 18, Issue:4 Topics: Animals; Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Lung Neoplasms; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Molecular Structure; Proline; Protease Inhibitors; Xenograft Model Antitumor Assays	2006
Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. Lung cancer (Amsterdam, Netherlands), 2007, Volume: 55, Issue:1 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Arginine; Carcinoma, Squamous Cell; Codon; Cyclin-Dependent Kinase Inhibitor p21; Female; Genetic Variation; Humans; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Proline; Risk Factors; Serine; Smoking; Tumor Suppressor Protein p53	2007
In vivo and in vitro antitumor effect of a unique nutrient mixture on lung cancer cell line A-549. Experimental lung research, 2006, Volume: 32, Issue:9 Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Dietary Supplements; Dose-Response Relationship, Drug; Drug Combinations; Drug Screening Assays, Antitumor; Humans; Laminin; Lung Neoplasms; Lysine; Mice; Mice, Nude; Plant Extracts; Proline; Proteoglycans	2006
Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells. American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:6 Topics: Animals; Antioxidants; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Hydrogen Peroxide; Indoles; Lung Neoplasms; Muridae; Phosphorylation; Piperazines; Proline; Proto-Oncogene Proteins c-met; Reactive Oxygen Species; Signal Transduction; Sulfonamides; Thiocarbamates; Tyrosine	2007
Lack of evidence that p53 Arg72Pro influences lung cancer prognosis: an analysis of survival in 619 female patients. Lung cancer (Amsterdam, Netherlands), 2007, Volume: 57, Issue:2 Topics: Amino Acid Substitution; Cohort Studies; Female; Humans; Lung Neoplasms; Middle Aged; Neoplasm Staging; Polymorphism, Single Nucleotide; Prognosis; Proline; Survival Analysis; Tumor Suppressor Protein p53	2007
Pre- and post-initiation chemoprevention activity of 2-alkyl/aryl selenazolidine-4(R)-carboxylic acids against tobacco-derived nitrosamine (NNK)-induced lung tumors in the A/J mouse. Chemico-biological interactions, 2007, Jul-20, Volume: 168, Issue:3 Topics: Animals; Carcinogens; Dietary Supplements; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Mice; Molecular Structure; Neoplasms, Experimental; Nicotiana; Nitrosamines; Organoselenium Compounds; Proline	2007
Essential role of Pyk2 and Src kinase activation in neuropeptide-induced proliferation of small cell lung cancer cells. Oncogene, 2008, Mar-13, Volume: 27, Issue:12 Topics: Calcium; Carcinoma, Small Cell; Cell Line; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Focal Adhesion Kinase 2; Galanin; Humans; Lung Neoplasms; Proline; src-Family Kinases	2008
Frequency of TP53 mutations in relation to Arg72Pro genotypes in non small cell lung cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:10 Topics: Aged; Alleles; Arginine; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplastic; Codon; DNA Mutational Analysis; Female; Gene Frequency; Genetic Carrier Screening; Genetic Predisposition to Disease; Genotype; Homozygote; Humans; Lung Neoplasms; Male; Middle Aged; Norway; Polymorphism, Single Nucleotide; Proline; Smoking; Tumor Suppressor Protein p53	2007
Prognostic impact of p53 Pro72 homozygous genotype in non-small cell lung cancer patients. Oncology reports, 2008, Volume: 19, Issue:3 Topics: Aged; Aged, 80 and over; Arginine; Carcinoma, Non-Small-Cell Lung; Codon; Female; Gene Frequency; Genes, p53; Genotype; Homozygote; Humans; Lung Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Prognosis; Proline; Survival Rate	2008
Lung cancer risk associated with Thr495Pro polymorphism of GHR in Chinese population. Japanese journal of clinical oncology, 2008, Volume: 38, Issue:4 Topics: Adenocarcinoma; Aged; Asian People; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Case-Control Studies; Chi-Square Distribution; Female; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Proline; Receptors, Somatotropin; Risk Assessment; Risk Factors; Smoking; Threonine	2008
Decrease in pyrrole-2-carboxylic acid excretion during lung cancer disease. Neoplasma, 1982, Volume: 29, Issue:5 Topics: Collagen; Humans; Hydroxyproline; Lung Neoplasms; Proline	1982
Higher lung cancer risk for younger African-Americans with the Pro/Pro p53 genotype. Carcinogenesis, 1995, Volume: 16, Issue:9 Topics: Aged; Alleles; Analysis of Variance; Base Sequence; Black People; Case-Control Studies; Female; Genes, p53; Genotype; Humans; Lung Neoplasms; Male; Mexican Americans; Middle Aged; Molecular Sequence Data; Polymorphism, Genetic; Proline; Risk Factors; Smoking	1995
A small proline-rich protein regulated by vitamin A in tracheal epithelial cells is induced in lung tumors. American journal of respiratory cell and molecular biology, 1993, Volume: 9, Issue:4 Topics: Amino Acid Sequence; Animals; Base Sequence; Biomarkers, Tumor; Blotting, Northern; Cells, Cultured; Cricetinae; DNA; Epithelial Cells; Haplorhini; Humans; In Situ Hybridization; Lung Neoplasms; Mesocricetus; Molecular Sequence Data; Peptide Biosynthesis; Peptides; Precipitin Tests; Proline; Proline-Rich Protein Domains; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Swine; Trachea; Vitamin A	1993
Binding of the proline-rich region of the epithelial Na+ channel to SH3 domains and its association with specific cellular proteins. The Biochemical journal, 1995, Dec-01, Volume: 312 ( Pt 2) Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Autoradiography; Binding Sites; Cell Line; Epithelium; Glutathione Transferase; Humans; Lung Neoplasms; Macromolecular Substances; Methionine; Molecular Sequence Data; Neoplasm Proteins; Phosphoproteins; Proline; Radioimmunoprecipitation Assay; Rats; Recombinant Fusion Proteins; Sodium Channels; src Homology Domains; Substrate Specificity; Sulfur Radioisotopes; Tumor Cells, Cultured	1995
Analysis of a germ line polymorphism of the p53 gene in lung cancer patients; discrete results with smoking history. Carcinogenesis, 1996, Volume: 17, Issue:2 Topics: Arginine; Base Sequence; Case-Control Studies; Disease Susceptibility; Female; Genes, p53; Genotype; Heterozygote; Homozygote; Humans; Lung Neoplasms; Male; Middle Aged; Molecular Sequence Data; Polymorphism, Genetic; Proline; Smoking	1996
Identification of a novel p53 functional domain that is necessary for efficient growth suppression. Proceedings of the National Academy of Sciences of the United States of America, 1996, Dec-24, Volume: 93, Issue:26 Topics: Amino Acid Sequence; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; Cell Line; Chickens; DNA Damage; Genes, p53; Haplorhini; Humans; Lung Neoplasms; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Rats; Recombinant Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53	1996
Glutathione-S-Transferase M1 and codon 72 p53 polymorphisms in a northwestern Mediterranean population and their relation to lung cancer susceptibility. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1996, Volume: 5, Issue:5 Topics: Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Amino Acid Sequence; Arginine; Carcinoma; Carcinoma, Small Cell; Codon; Female; Gene Deletion; Gene Frequency; Genes, p53; Genetic Predisposition to Disease; Genotype; Glutathione Transferase; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Proline; Risk Factors; Smoking; Spain	1996
Prolidase and prolinase activities in moderately and poorly differentiated lung adenocarcinoma. Roczniki Akademii Medycznej w Bialymstoku (1995), 1997, Volume: 42 Suppl 1 Topics: Adenocarcinoma; Cell Differentiation; Collagen; Dipeptidases; Humans; Hydroxyproline; Lung; Lung Neoplasms; Neoplasm Proteins; Peptide Fragments; Proline	1997
Prolidase activity and beta 1 integrin expression in moderately and poorly differentiated lung adenocarcinomas. Roczniki Akademii Medycznej w Bialymstoku (1995), 1997, Volume: 42 Suppl 1 Topics: Adenocarcinoma; Cell Differentiation; Collagen; Dipeptidases; Humans; Integrin beta1; Lung; Lung Neoplasms; Neoplasm Proteins; Proline	1997
Correlation of the mutation of p53 gene and the polymorphism at codon 72 in smoking-related non-small cell lung cancer patients. International journal of oncology, 1998, Volume: 12, Issue:3 Topics: Adenocarcinoma; Aged; Alleles; Arginine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Codon; Disease Susceptibility; Female; Genes, p53; Genetic Carrier Screening; Humans; Lung Diseases; Lung Neoplasms; Male; Middle Aged; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Risk Factors; Smoking	1998
Cyclooxygenase-2 expression is abundant in alveolar type II cells in lung cancer-sensitive mouse strains and in premalignant lesions. Carcinogenesis, 2000, Volume: 21, Issue:7 Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Susceptibility; Humans; Isoenzymes; Lung Neoplasms; Membrane Proteins; Mice; Mice, Inbred A; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Nitrosamines; Precancerous Conditions; Proline; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Pyrazoles; RNA, Messenger; Sulfonamides; Thiocarbamates; Transcription, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured	2000
Collagen metabolism disturbances are accompanied by an increase in prolidase activity in lung carcinoma planoepitheliale. International journal of experimental pathology, 2000, Volume: 81, Issue:5 Topics: Biomarkers, Tumor; Blotting, Western; Collagen; Dipeptidases; Humans; Integrin beta1; Lung Neoplasms; Neoplasm Proteins; Proline	2000
Differential association of the codon 72 p53 and GSTM1 polymorphisms on histological subtype of non-small cell lung carcinoma. Cancer research, 2001, Dec-15, Volume: 61, Issue:24 Topics: Adenocarcinoma; Aged; Alleles; Arginine; Carcinoma, Squamous Cell; Case-Control Studies; Codon; Female; Genes, p53; Genetic Predisposition to Disease; Genotype; Glutathione Transferase; Humans; Logistic Models; Lung Neoplasms; Male; Middle Aged; Polymorphism, Genetic; Proline	2001
The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells. Oncogene, 2002, Jan-03, Volume: 21, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Clone Cells; Colchicine; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Daunorubicin; DNA Damage; DNA, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Lung Neoplasms; Models, Biological; Proline; Promoter Regions, Genetic; Protein Structure, Tertiary; Recombinant Fusion Proteins; Structure-Activity Relationship; Tetracycline; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2002
Null carcinogenic effect of large doses of nitrosoproline and nitrosohydroxyproline in Wistar rats. Food and cosmetics toxicology, 1976, Volume: 14, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Dimethylnitrosamine; Drug Synergism; Fatty Acids, Unsaturated; Hydroxyproline; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Proline; Rats	1976
Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potentials. Cancer research, 1987, Sep-15, Volume: 47, Issue:18 Topics: Adenocarcinoma; Animals; Basement Membrane; Clone Cells; Collagen; Culture Media; Extracellular Matrix; Female; Lung; Lung Neoplasms; Mammary Neoplasms, Experimental; Molecular Weight; Neoplasm Metastasis; Proline; Rats; Rats, Inbred F344	1987
Failure to induce tumors in Swiss mice after concurrent administration of amino acids and sodium nitrite. Journal of the National Cancer Institute, 1972, Volume: 48, Issue:5 Topics: Adenoma; Animals; Arginine; Carcinogens; Female; Hydroxyproline; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrites; Nitroso Compounds; Piperidines; Proline; Pyrrolidines	1972