Compounds > proline

proline and Insulin Resistance

proline has been researched along with Insulin Resistance in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's3 (8.82)18.2507
2000's19 (55.88)29.6817
2010's8 (23.53)24.3611
2020's3 (8.82)2.80

Authors

AuthorsStudies
Kang, S; Kim, HR; Kim, JH; Kim, TW; Lee, AR; Lee, E; Lee, JE1
Abd El-Aty, AM; Cho, W; Hacimuftuoglu, A; Jeong, JH; Jung, TW; Kim, H; Lee, HJ; Oh, H; Park, SY1
Altıntaş, E; Ateş, F; Özdoğan, O; Sezgin, O; Üçbilek, E; Yaraş, S1
Hou, B; Meng, F; Ren, S; Ren, Z; Wang, Y; Xie, F; Zhu, J1
Chen, SC; Chuang, WL; Dai, CY; Hsieh, MH; Huang, CF; Huang, CI; Huang, JF; Liang, PC; Lin, YH; Lin, ZY; Yang, JF; Yeh, ML; Yu, ML1
Afef, S; Fadhel, NM; Fadoua, N; Khaldoun, BH; Mohamed, N; Naceur, SM; Youssef, SM1
Black, MH; Buchanan, TA; Haritunians, T; Lawrence, JM; Takayanagi, M; Taylor, KD; Trigo, E; Wang, N; Watanabe, RM; Wu, J; Xiang, AH1
Ando, F; Iguchi, A; Kuzuya, M; Shimokata, H1
Danielsson, P; Johansson, LE; Marcus, C; Norgren, S; Ridderstråle, M1
Dugi, KA; Schiekofer, S; Schlimmer, P; Schneider, JG; von Eynatten, M1
Mensink, RP; Popeijus, HE; van Meijl, LE1
Benhamou, Y; Bradford, B; Couzigou, P; Forestier, N; Guyader, D; Larrey, D; Marcellin, P; Moucari, R; Seiwert, S; Vidaud, M; Voitot, H; Zeuzem, S1
Chen, H; Chen, J; Hu, H; Mohan, V; Tang, Y; Venkatesan, R; Wang, J; Zhang, H; Zhu, S1
Canizales-Quinteros, S; Fernández, J; Hinojosa-Cruz, JC; López-Alarcón, M; Rodríguez-Cruz, M; Vital-Reyes, VS; Zavala-Ortega, MI1
Hirose, H; Miyashita, K; Nishikai, K; Saito, I; Saruta, T; Taniyama, M; Tomita, M; Yamamoto, Y1
Berenson, GS; Boerwinkle, E; Chen, W; Li, S; Srinivasan, SR1
Epe, M; Fehmann, HC; Gross, U1
Alemanno, I; Buzzetti, R; Caiazzo, AM; Capizzi, M; di Mario, U; Mein, CA; Osborn, JA; Petrone, A; Vania, A; Zavarella, S1
Charles, MA; Charpentier, G; Clément, K; Froguel, P; Ghoussaini, M; Lobbens, S; Meyre, D; Tauber, M; Weill, J1
Aubert, R; Balkau, B; Bellili, N; Froguel, P; Fumeron, F; Jaziri, R; Lahmidi, S; Lobbens, S; Marre, M; Péan, F; Porchay, I; Tichet, J; Vaxillaire, M1
Gong, KB; Ku, DC; Kuo, TC; Liang, SF; Lin, TC; Wu, MJ; Yen, JM1
Xie, J; Yu, Y; Zhang, A; Zhang, J; Zhang, M1
Arslan, M; Cakir, N; Ergün, MA; Karakoç, A; Yilmaz, M; Yurtçu, E1
Agostoni, C; Biondi, ML; Giovannini, M; Radaelli, G; Salvioni, M; Scaglioni, S; Verduci, E1
Adeli, K; Bahrami, Y; Ghaemi, A; Khatami, S; Khoshbin, E; Larijani, B; Meshkani, R; Mirkhani, F; Molapour, A; Sadeghi, S; Taghikhani, M1
Aro, A; Groop, L; Lyssenko, V; Salminen, I; Saloranta, C; Virtanen, SM; Ylönen, SK1
Bernal, R; Cardona, F; Macias-Gonzalez, M; Martin, M; Queipo-Ortuño, M; Tinahones, FJ1
Akanuma, Y; Beamer, BA; Kadowaki, H; Kadowaki, T; Katakura, T; Kim-Motoyama, H; Mori, Y; Shuldiner, AR; Yasuda, K; Yazaki, Y1
Deninger, M; Haist, K; Häring, HU; Koch, M; Maerker, E; Renn, W; Rett, K; Volk, A1
Andersen, G; Berglund, L; Borch-Johnsen, K; Carstensen, B; Drivsholm, T; Ek, J; Hansen, L; Hansen, T; Lithell, H; Pedersen, O; Urhammer, SA1
Chen, YD; Chuang, LM; Cox, D; Ho, LT; Hsiung, CA; Lei, HH; Nakatsuka, CH; Pei, D; Pratt, RE; Sheu, WH; Tai, TY1
Ishibashi, K; Kageyama, S; Mimura, A; Nemoto, M; Sakurai, T; Sasaki, T; Tajima, N; Yamamoto, J; Yokota, K1
Klinkhamer, MP; Krans, HM; Maassen, JA; Möller, W; Van der Vorm, ER; Van der Zon, GC1
Groen, NA; Klinkhamer, MP; Krans, HM; Lindhout, D; Maassen, JA; Möller, W; Sandkuyl, LA; van der Zon, GC1

Reviews

1 review(s) available for proline and Insulin Resistance

ArticleYear
Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated with nephropathy in type 2 diabetes: evidence from meta-analysis of 18 studies.
    Diabetes care, 2012, Volume: 35, Issue:6

    Topics: Alanine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Genetic Predisposition to Disease; Genotype; Humans; Insulin Resistance; Kidney Failure, Chronic; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; PPAR gamma; Proline

2012

Trials

1 trial(s) available for proline and Insulin Resistance

ArticleYear
Danoprevir, an HCV NS3/4A protease inhibitor, improves insulin sensitivity in patients with genotype 1 chronic hepatitis C.
    Gut, 2010, Volume: 59, Issue:12

    Topics: Adult; Antiviral Agents; Cyclopropanes; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Isoindoles; Lactams; Lactams, Macrocyclic; Male; Middle Aged; Proline; Protease Inhibitors; RNA, Viral; Sulfonamides; Viral Load; Viral Nonstructural Proteins

2010

Other Studies

32 other study(ies) available for proline and Insulin Resistance

ArticleYear
Stachydrine derived from fermented rice prevents diet-induced obesity by regulating adipsin and endoplasmic reticulum homeostasis.
    The Journal of nutritional biochemistry, 2022, Volume: 107

    Topics: 3T3-L1 Cells; Animals; Complement Factor D; Diet, High-Fat; Endoplasmic Reticulum; Homeostasis; Insulin Resistance; Mice; Mice, Inbred C57BL; Obesity; Oryza; Proline

2022
Stachydrine alleviates lipid-induced skeletal muscle insulin resistance via AMPK/HO-1-mediated suppression of inflammation and endoplasmic reticulum stress.
    Journal of endocrinological investigation, 2022, Volume: 45, Issue:11

    Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Endoplasmic Reticulum Stress; Glucose; Inflammation; Insulin; Insulin Resistance; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Palmitates; Proline; RNA; Tumor Necrosis Factor-alpha

2022
The impact of direct-acting antiviral treatment on lipid metabolism and insulin resistance in chronic hepatitis C patients: temporary? permanent?
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2020, Volume: 31, Issue:5

    Topics: Aged; Anilides; Antiviral Agents; Benzimidazoles; Blood Glucose; Cholesterol; Cyclopropanes; Drug Therapy, Combination; Female; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Lactams, Macrocyclic; Lipid Metabolism; Lipoproteins, LDL; Male; Middle Aged; Proline; Ribavirin; Ritonavir; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Triglycerides; Valine

2020
Inhibition of NF-κB activation improves insulin resistance of L6 cells.
    Endocrine journal, 2017, Jul-28, Volume: 64, Issue:7

    Topics: Absorption, Physiological; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Survival; Glucose; Hydrogen Peroxide; Inflammation Mediators; Insulin Resistance; Kinetics; MAP Kinase Signaling System; Muscle, Skeletal; NF-kappa B; Oxidants; Oxidative Stress; Proline; Rats; Thiocarbamates

2017
The outcomes of glucose abnormalities in chronic hepatitis C patients receiving interferon-free direct antiviral agents.
    The Kaohsiung journal of medical sciences, 2017, Volume: 33, Issue:11

    Topics: 2-Naphthylamine; Aged; Anilides; Antiviral Agents; Carbamates; Cyclopropanes; Drug Therapy, Combination; Female; Genotype; Glucose; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Insulin Resistance; Insulin-Secreting Cells; Isoquinolines; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Proline; Prospective Studies; Pyrrolidines; Ritonavir; Sofosbuvir; Sulfonamides; Uracil; Valine

2017
A Pro 12 Ala substitution in the PPARγ2 polymorphism may decrease the number of diseased vessels and the severity of angiographic coronary artery.
    Coronary artery disease, 2013, Volume: 24, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitution; Biomarkers; Blood Glucose; Case-Control Studies; Chi-Square Distribution; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Genetic; PPAR gamma; Predictive Value of Tests; Proline; Risk Factors; Severity of Illness Index

2013
Variation in PPARG is associated with longitudinal change in insulin resistance in Mexican Americans at risk for type 2 diabetes.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:3

    Topics: Adult; Alanine; Amino Acid Substitution; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Humans; Insulin Resistance; Longitudinal Studies; Male; Mexican Americans; Polymorphism, Single Nucleotide; PPAR gamma; Proline; Young Adult

2015
Glutathione peroxidase 1 Pro198Leu variant contributes to the metabolic syndrome in men in a large Japanese cohort.
    The American journal of clinical nutrition, 2008, Volume: 87, Issue:6

    Topics: Adipose Tissue; Adult; Aged; Amino Acid Substitution; Body Size; Cohort Studies; DNA Primers; Female; Gene Frequency; Genetic Variation; Genotype; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Insulin Resistance; Japan; Leucine; Longevity; Longitudinal Studies; Male; Metabolic Syndrome; Middle Aged; Polymorphism, Single Nucleotide; Proline; Sex Characteristics

2008
Interaction between PPARG Pro12Ala and ADIPOQ G276T concerning cholesterol levels in childhood obesity.
    International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity, 2009, Volume: 4, Issue:2

    Topics: Adiponectin; Adolescent; Alanine; Body Mass Index; Child; Cholesterol; Cross-Sectional Studies; Female; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Homozygote; Humans; Insulin Resistance; Lipids; Male; Obesity; Polymorphism, Genetic; PPAR gamma; Proline; Risk Assessment; Risk Factors

2009
The proline 12 alanine substitution in the PPARgamma2 gene is associated with increased extent of coronary artery disease in men.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2009, Volume: 117, Issue:9

    Topics: Age Factors; Aged; Alanine; Alleles; Angiography; Coronary Artery Disease; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Insulin Resistance; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline; Protein Isoforms; Regression Analysis

2009
Amino acids stimulate Akt phosphorylation, and reduce IL-8 production and NF-κB activity in HepG2 liver cells.
    Molecular nutrition & food research, 2010, Volume: 54, Issue:11

    Topics: Glutamine; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Interleukin-1beta; Interleukin-8; Leucine; Models, Biological; NF-kappa B; Phosphorylation; Proline; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Necrosis Factor-alpha

2010
PPARγ2 Pro12Ala polymorphism is associated with improved lipoprotein lipase functioning in adipose tissue of insulin resistant obese women.
    Gene, 2012, Dec-15, Volume: 511, Issue:2

    Topics: Adipose Tissue; Adult; Alanine; Base Sequence; DNA Primers; Female; Humans; Insulin Resistance; Lipoprotein Lipase; Middle Aged; Obesity; Polymerase Chain Reaction; PPAR gamma; Proline

2012
PPAR(gamma)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:11

    Topics: Adiponectin; Adult; Alanine; Alleles; Asian People; Blood Glucose; Body Mass Index; Female; Humans; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Japan; Lipids; Male; Middle Aged; Polymorphism, Genetic; Proline; Proteins; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2002
The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study.
    Diabetes, 2003, Volume: 52, Issue:5

    Topics: Adult; Aging; Alanine; Amino Acid Substitution; Blood Glucose; Child; Genotype; Homeostasis; Humans; Insulin; Insulin Resistance; Mutation, Missense; Polymorphism, Single Nucleotide; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2003
A new mutation in the hepatocyte nuclear factor-1-alpha gene (P224S) in a newly discovered German family with maturity-onset diabetes of the young 3 (MODY 3). Family members carry additionally the homozygous I27L amino acid polymorphism in the HNF1 alpha
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2004, Volume: 112, Issue:2

    Topics: Adolescent; Aged; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Exons; Female; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Homozygote; Humans; Insulin Resistance; Isoleucine; Leucine; Male; Mutation; Nuclear Proteins; Proline; Serine; Transcription Factors

2004
PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity.
    Pediatric research, 2005, Volume: 57, Issue:1

    Topics: Adolescent; Alanine; Child; Exons; Female; Genetic Variation; Genotype; Humans; Insulin; Insulin Resistance; Italy; Linear Models; Male; Mutation, Missense; Obesity; Phenotype; Polymorphism, Genetic; PPAR gamma; Proline; Risk Factors

2005
Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.
    BMC medical genetics, 2005, Mar-22, Volume: 6

    Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Case-Control Studies; Child; Diabetes Mellitus, Type 2; Female; France; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Single Nucleotide; PPAR gamma; Proline; White People

2005
The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the Data From an Epidemiological Study on the Insulin Resistance
    Diabetes, 2006, Volume: 55, Issue:4

    Topics: Adiponectin; Adult; Alanine; Amino Acid Substitution; Diabetes Mellitus; Genotype; Humans; Hyperglycemia; Hyperinsulinism; Insulin Resistance; Middle Aged; Polymorphism, Single Nucleotide; PPAR gamma; Proline

2006
Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.
    BMC medical genetics, 2006, Apr-07, Volume: 7

    Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Arginine; Diabetes Mellitus; Female; Glucose Intolerance; Glucose Metabolism Disorders; Glucose Tolerance Test; Glycine; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Phosphoproteins; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Proline; Prospective Studies; Taiwan

2006
The influence of the Pro12Ala mutation of PPARgamma2 receptor gene on beta-cells restoration and insulin resistance in type 2 diabetes with hypertension.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005, Volume: 25, Issue:6

    Topics: Alanine; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Hypertension; Insulin Resistance; Insulin-Secreting Cells; Mutation; PPAR gamma; Proline

2005
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in women with polycystic ovary syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2006, Volume: 22, Issue:6

    Topics: Adult; Alanine; Androstenedione; Blood Glucose; C-Peptide; Dehydroepiandrosterone Sulfate; Female; Follicle Stimulating Hormone; Glucose Tolerance Test; Heterozygote; Homeostasis; Humans; Insulin; Insulin Resistance; Luteinizing Hormone; Polycystic Ovary Syndrome; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; PPAR gamma; Proline; Testosterone

2006
PPAR-gamma2 Pro12Ala variant, insulin resistance and plasma long-chain polyunsaturated fatty acids in childhood obesity.
    Pediatric research, 2006, Volume: 60, Issue:4

    Topics: Alanine; Child; Fatty Acids, Unsaturated; Female; Gene Frequency; Humans; Insulin Resistance; Male; Obesity; Phospholipids; Polymorphism, Genetic; PPAR gamma; Proline

2006
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population.
    Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:4

    Topics: Alanine; Base Sequence; Diabetes Mellitus, Type 2; DNA Primers; Genetic Predisposition to Disease; Humans; Insulin Resistance; Iran; Polymorphism, Genetic; PPAR gamma; Proline

2007
The Pro12Ala polymorphism of the PPAR-gamma2 gene affects associations of fish intake and marine n-3 fatty acids with glucose metabolism.
    European journal of clinical nutrition, 2008, Volume: 62, Issue:12

    Topics: Alanine; Alleles; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet Records; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Female; Genotype; Heterozygote; Homozygote; Humans; Insulin; Insulin Resistance; Lipids; Male; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline; Sex Factors

2008
PPARgamma mRNA expression is reduced in peripheral blood mononuclear cells after fat overload in patients with metabolic syndrome.
    The Journal of nutrition, 2008, Volume: 138, Issue:5

    Topics: Alanine; Body Mass Index; Dietary Fats; Gene Expression; Glutathione; Humans; Insulin Resistance; Leukocytes, Mononuclear; Lipid Peroxidation; Metabolic Syndrome; NF-kappa B; Oxidative Stress; Polymerase Chain Reaction; Polymorphism, Genetic; PPAR gamma; Proline; Protein Carbonylation; RNA, Messenger; Triglycerides

2008
Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men.
    Biochemical and biophysical research communications, 1998, Oct-09, Volume: 251, Issue:1

    Topics: Adipose Tissue; Adult; Aged; Alanine; Amino Acid Substitution; Blood Pressure; Body Mass Index; Fats; Genetic Variation; Humans; Insulin Resistance; Japan; Lipids; Male; Middle Aged; Nuclear Proteins; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors

1998
The PPARgamma2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects.
    Diabetologia, 1999, Volume: 42, Issue:6

    Topics: Adult; Alanine; Amino Acid Substitution; Codon; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Male; Mutation; Obesity; Polymorphism, Genetic; Proline; Quantitative Trait, Heritable; Receptors, Cytoplasmic and Nuclear; Transcription Factors

1999
Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians.
    Diabetologia, 2001, Volume: 44, Issue:9

    Topics: Aged; Alanine; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin Resistance; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proline; Receptors, Cytoplasmic and Nuclear; Sweden; Transcription Factors

2001
Sibling-based association study of the PPARgamma2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families: a SAPPHIRe study. Stanford Asian-Pacific Program in Hypertension and Insulin Resistance.
    Journal of molecular medicine (Berlin, Germany), 2001, Volume: 79, Issue:11

    Topics: Adult; Age Factors; Aged; Alanine; Alleles; Blood Glucose; China; Family Health; Female; Genotype; Glucose Tolerance Test; Homozygote; Humans; Hypertension; Insulin Resistance; Japan; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Regression Analysis; Sex Factors; Time Factors; Transcription Factors

2001
PPARgamma2 pro12Ala polymorphism and insulin resistance in Japanese hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:1

    Topics: Adult; Alanine; Alleles; Amino Acid Substitution; Arginine; Asian People; Gene Frequency; Genotype; Humans; Hypertension; Insulin Resistance; Japan; Male; Middle Aged; Polymorphism, Genetic; Proline; Receptors, Adrenergic, beta; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan

2002
A leucine to proline mutation at position 233 in the insulin receptor inhibits cleavage of the proreceptor and transport to the cell surface.
    Biochemistry, 1991, Nov-05, Volume: 30, Issue:44

    Topics: Animals; Biological Transport; Cell Line; Cell Membrane; CHO Cells; Cricetinae; Gene Expression; Humans; Immunosorbent Techniques; Insulin; Insulin Resistance; Kinetics; Leucine; Mutation; Phosphorylation; Proline; Protein Precursors; Receptor, Insulin; Transfection

1991
A leucine-to-proline mutation in the insulin receptor in a family with insulin resistance.
    The EMBO journal, 1989, Volume: 8, Issue:9

    Topics: Cells, Cultured; Cloning, Molecular; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; Fibroblasts; Genotype; Humans; Insulin Resistance; Leucine; Male; Mutation; Pedigree; Proline; Radioligand Assay; Receptor, Insulin

1989