proline and Idiopathic Parkinson Disease

proline has been researched along with Idiopathic Parkinson Disease in 32 studies

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (15.63)	18.7374
1990's	2 (6.25)	18.2507
2000's	13 (40.63)	29.6817
2010's	10 (31.25)	24.3611
2020's	2 (6.25)	2.80

Authors

Authors	Studies
Julku, UH; Kilpeläinen, T; Myöhänen, TT; Svarcbahs, R	1
Cui, H; Erlandsson, A; Falk, A; Jäntti, M; Kukkonen, JP; Myöhänen, T; Rinne, MK; Rostami, J	1
Andreas, LB; Baker, JD; Becker, S; Blair, LJ; Favretto, F; Flores, D; Strohäker, T; Zweckstetter, M	1
Bindoff, LA; Haugarvoll, K	1
Huttunen, HJ; Myöhänen, TT; Savolainen, MH; Yan, X	1
An, R; Chen, Y; Tian, S; Xu, Y; Yang, X; Zhao, Q; Zheng, J	1
Cheng, L; Li, JY; Li, NN; Lu, ZJ; Peng, R; Sun, XY; Tan, EK; Wang, L; Zhang, JH	1
Julku, UH; Myöhänen, TT; Svarcbahs, R	1
Ross, OA; Tan, EK; Tan, LC; Tang, M; Wu, RM; Wu, YR; Zhao, Y	1
An, X; Burgunder, JM; Chen, W; Gou, Y; Mao, X; Peng, R; Wang, Y; Wu, Y; Xu, Y; Yuan, G; Zhang, J; Zhang, Z	1
Bax, A; Bodner, CR; Dobson, CM; Maltsev, AS	1
Guo, JF; Pan, Q; Sun, QY; Tang, BS; Wang, L; Xia, K; Yao, LY; Yu, RH; Zuo, X	1
Cornejo Castro, EM; Fog, K; Jensen, PH; Kahle, PJ; Rannikko, EH; Shaik, JH; Vesterager, LB; Weber, SS	1
Augustin, J; Ayrignac, X; Campion, D; Clanet, M; Coutant, S; Defebvre, L; Frébourg, T; Guyant-Maréchal, L; Hannequin, D; Krystkowiak, P; Labauge, P; Le Ber, I; Lefaucheur, R; Legallic, S; Maltête, D; Martinaud, O; Nicolas, G; Pariente, J; Pottier, C; Rousseau, S; Rovelet-Lecrux, A; Vaschalde, Y	1
Bussell, R; Eliezer, D	1
Frasier, M; Haas, C; Kahle, P; Lee, JM; Magnuson, D; McCarthy, L; Walzer, M; Wolozin, B	1
Butterfield, DA; Calabrese, V; Frasier, M; Poon, HF; Shreve, N; Wolozin, B	1
Kobayashi, N; Ochiai, S; Sode, K; Usuzaka, E	1
Aasly, JO; Farrer, MJ; Pielsticker, L; Ross, OA; Toft, M	1
Allen-Auerbach, M; Doostzadeh, J; Langston, JW; Schüle, B; Tetrud, JW	1
Chen, S; Deng, X; Ding, X; Dong, H; Li, W; Li, X; Ma, G; Wu, T; Yao, J; Zeng, Y; Zhang, X	1
Annesi, F; Annesi, G; Carrideo, S; Cirò Candiano, IC; Civitelli, D; Condino, F; De Marco, EV; Messina, D; Morelli, M; Nicoletti, G; Novellino, F; Provenzano, G; Quattrone, A; Rocca, FE; Tarantino, P	1
Bird, TD; Griffith, A; Leis, BC; Leverenz, JB; Mata, IF; Roberts, JW; Samii, A; Schellenberg, GD; Schneer, SH; Sidransky, E; Tsuang, D; Zabetian, CP	1
Bock, H; Hilbig, A; Jardim, LB; Michelin-Tirelli, K; Rieder, CR; Saraiva-Pereira, ML; Socal, MP	1
Blanchard, PJ; Falkous, G; Ishiura, S; Mantle, D; Perry, EK	1
Epplen, JT; Graeber, M; Kösel, S; Krüger, R; Kuhn, W; Müller, T; Przuntek, H; Riess, O; Schöls, L; Woitalla, D	1
Conway, KA; Harper, JD; Lansbury, PT	1
Amsler, U; Cuénod, M; Perschak, H; Siegfried, J; Vischer, A	1
Chase, TN; Lipton, MA; Morris, CE; Woods, AC	1
Barbeau, A; Kastin, AJ	1
Beasley, BL; Boehme, DH; Chambers, RA; Hare, TA; Vogel, WH	1
Brune, GG; Pflughaupt, KW	1

Reviews

1 review(s) available for proline and Idiopathic Parkinson Disease

Article	Year
Mutational scanning of the CHCHD2 gene in Han Chinese patients with Parkinson's disease and meta-analysis of the literature. Parkinsonism & related disorders, 2016, Volume: 29 Topics: Adult; Aged; Asian People; DNA Mutational Analysis; DNA-Binding Proteins; Genetic Association Studies; Genotype; Humans; Leucine; Middle Aged; Mitochondrial Proteins; Mutation; Parkinson Disease; Proline; Transcription Factors	2016

Article

Year

Mutational scanning of the CHCHD2 gene in Han Chinese patients with Parkinson's disease and meta-analysis of the literature.

Parkinsonism & related disorders, 2016, Volume: 29

Topics: Adult; Aged; Asian People; DNA Mutational Analysis; DNA-Binding Proteins; Genetic Association Studies; Genotype; Humans; Leucine; Middle Aged; Mitochondrial Proteins; Mutation; Parkinson Disease; Proline; Transcription Factors

2016

Other Studies

31 other study(ies) available for proline and Idiopathic Parkinson Disease

Article	Year
Behavioural and dopaminergic changes in double mutated human A30PA53T alpha-synuclein transgenic mouse model of Parkinson´s disease. Scientific reports, 2019, 11-22, Volume: 9, Issue:1* Topics: Aging; Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Humans; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Parkinson Disease; Proline; Threonine	2019
Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 131 Topics: alpha-Synuclein; Astrocytes; Autophagy; Cell Line, Tumor; Cells, Cultured; Disease Progression; Humans; Neurons; Parkinson Disease; Proline; Prolyl Oligopeptidases; Serine Proteinase Inhibitors	2020
Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war. Nature communications, 2020, 11-27, Volume: 11, Issue:1 Topics: alpha-Synuclein; Amyloid; Catalysis; Cyclophilin A; Cyclosporine; Humans; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Chaperones; Parkinson Disease; Proline; Protein Aggregates; Protein Binding; Protein Domains	2020
A novel compound heterozygous tyrosine hydroxylase mutation (p.R441P) with complex phenotype. Journal of Parkinson's disease, 2011, Volume: 1, Issue:1 Topics: Adult; Arginine; Heterozygote; Humans; Male; Mutation, Missense; Parkinson Disease; Phenotype; Proline; Tyrosine 3-Monooxygenase	2011
Prolyl oligopeptidase enhances α-synuclein dimerization via direct protein-protein interaction. The Journal of biological chemistry, 2015, Feb-20, Volume: 290, Issue:8 Topics: alpha-Synuclein; Amino Acid Substitution; Animals; Autophagy; Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Mice; Mutation, Missense; Parkinson Disease; Proline; Prolyl Oligopeptidases; Protein Multimerization; Protein Structure, Tertiary; Serine Endopeptidases	2015
Genetic analysis of CHCHD2 gene in Chinese Parkinson's disease. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2016, Volume: 171, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Alleles; Asian People; China; DNA-Binding Proteins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Leucine; Male; Middle Aged; Mitochondrial Proteins; Mutation; Parkinson Disease; Proline; Risk Factors; Transcription Factors	2016
Inhibition of Prolyl Oligopeptidase Restores Spontaneous Motor Behavior in the α-Synuclein Virus Vector-Based Parkinson's Disease Mouse Model by Decreasing α-Synuclein Oligomeric Species in Mouse Brain. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 12-07, Volume: 36, Issue:49 Topics: alpha-Synuclein; Animals; Brain Chemistry; Endopeptidase K; Forelimb; Genetic Vectors; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neural Pathways; Parkinson Disease; Proline; Prolyl Oligopeptidases; Protease Inhibitors; Serine Endopeptidases; Tyrosine 3-Monooxygenase	2016
Lrrk2 R1628P in non-Chinese Asian races. Annals of neurology, 2008, Volume: 64, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Arginine; Asian People; Female; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Proline; Protein Serine-Threonine Kinases	2008
LRRK2 R1628P variant is a risk factor of Parkinson's disease among Han-Chinese from mainland China. Movement disorders : official journal of the Movement Disorder Society, 2009, Oct-15, Volume: 24, Issue:13 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Asian People; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Protein Serine-Threonine Kinases; Young Adult	2009
Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy. Biochemistry, 2010, Feb-09, Volume: 49, Issue:5 Topics: Alanine; alpha-Synuclein; Genetic Variation; Glutamic Acid; Humans; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Parkinson Disease; Peptide Fragments; Phospholipids; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Solutions; Threonine	2010
Glucocerebrosidase gene L444P mutation is a risk factor for Parkinson's disease in Chinese population. Movement disorders : official journal of the Movement Disorder Society, 2010, Jun-15, Volume: 25, Issue:8 Topics: Adult; Asian People; Case-Control Studies; Chi-Square Distribution; DNA Mutational Analysis; Female; Glucosylceramidase; Humans; Leucine; Male; Meta-Analysis as Topic; Middle Aged; Mutation; Parkinson Disease; Proline	2010
Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion. Journal of neurochemistry, 2013, Volume: 125, Issue:2 Topics: Amino Acid Sequence; Animals; Cell Line; Disease Models, Animal; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; Multiple System Atrophy; Oncogene Proteins; Parkinson Disease; Peroxiredoxins; Point Mutation; Proline; Protein Deglycase DJ-1; Protein Stability; Protein Structure, Quaternary; Rats; Transfection	2013
Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification. Neurology, 2013, Jan-08, Volume: 80, Issue:2 Topics: Adult; Aged; Amino Acid Substitution; Arginine; Basal Ganglia Diseases; Calcinosis; Child; Databases, Genetic; Exome; Female; Humans; Leucine; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neurologic Examination; Parkinson Disease; Pedigree; Polymerase Chain Reaction; Proline; Receptor, Platelet-Derived Growth Factor beta; Tomography, X-Ray Computed; Tryptophan	2013
Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein. Biochemistry, 2004, Apr-27, Volume: 43, Issue:16 Topics: Alanine; alpha-Synuclein; Humans; Lipid Metabolism; Liposomes; Micelles; Mutation, Missense; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease; Phosphatidic Acids; Phosphatidylcholines; Proline; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Synucleins; Threonine	2004
Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein. Experimental neurology, 2005, Volume: 192, Issue:2 Topics: Age Factors; Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Blotting, Western; Brain; Disease Models, Animal; Female; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Movement Disorders; Mutation; Nerve Tissue Proteins; Neurons; Parkinson Disease; Phosphorylation; Proline; Synucleins; tau Proteins	2005
Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease. Neurobiology of disease, 2005, Volume: 18, Issue:3 Topics: Alanine; alpha-Synuclein; Animals; Brain; Disease Models, Animal; Energy Metabolism; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondrial Proteins; Nerve Tissue Proteins; Oxidative Stress; Parkinson Disease; Proline; Synucleins	2005
Engineered alpha-synuclein prevents wild type and familial Parkin variant fibril formation. Biochemical and biophysical research communications, 2005, Sep-23, Volume: 335, Issue:2 Topics: alpha-Synuclein; Alzheimer Disease; Amino Acid Sequence; Amyloid; Bone Marrow Cells; Circular Dichroism; DNA; DNA, Complementary; Gene Library; Humans; Light; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Parkinson Disease; Peptides; Polymerase Chain Reaction; Proline; Protein Binding; Protein Conformation; Protein Engineering; Protein Structure, Secondary; Scattering, Radiation; Synucleins; Time Factors; Ubiquitin-Protein Ligases; Ultraviolet Rays; Valine	2005
Glucocerebrosidase gene mutations and Parkinson disease in the Norwegian population. Neurology, 2006, Feb-14, Volume: 66, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Asparagine; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine	2006
Novel features in a patient homozygous for the L347P mutation in the PINK1 gene. Parkinsonism & related disorders, 2007, Volume: 13, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Homozygote; Humans; Lysine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Protein Kinases	2007
A novel P755L mutation in LRRK2 gene associated with Parkinson's disease. Neuroreport, 2006, Dec-18, Volume: 17, Issue:18 Topics: Adult; Aged; Aged, 80 and over; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Leucine; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2006
Glucocerebrosidase gene mutations are associated with Parkinson's disease in southern Italy. Movement disorders : official journal of the Movement Disorder Society, 2008, Feb-15, Volume: 23, Issue:3 Topics: Aged; Asparagine; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Italy; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine	2008
Glucocerebrosidase gene mutations: a risk factor for Lewy body disorders. Archives of neurology, 2008, Volume: 65, Issue:3 Topics: Aged; Asparagine; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucosylceramidase; Humans; Leucine; Lewy Body Disease; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Risk Factors; Serine	2008
Parkinson's disease and the heterozygous state for glucocerebrosidase mutations among Brazilians. Parkinsonism & related disorders, 2009, Volume: 15, Issue:1 Topics: Adult; Asparagine; Brazil; Female; Glucosylceramidase; Heterozygote; Humans; Leucine; Male; Middle Aged; Mutation; Parkinson Disease; Proline; Serine	2009
Comparison of proline endopeptidase activity in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease. Clinica chimica acta; international journal of clinical chemistry, 1996, May-30, Volume: 249, Issue:1-2 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Dementia; Female; Humans; Huntington Disease; Lewy Bodies; Male; Parkinson Disease; Proline; Prolyl Oligopeptidases; Serine Endopeptidases; Tissue Distribution	1996
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nature genetics, 1998, Volume: 18, Issue:2 Topics: Alanine; alpha-Synuclein; Amino Acid Sequence; Base Sequence; Female; Humans; Male; Nerve Tissue Proteins; Parkinson Disease; Pedigree; Point Mutation; Polymorphism, Single-Stranded Conformational; Proline; Synucleins	1998
Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid. Biochemistry, 2000, Mar-14, Volume: 39, Issue:10 Topics: Alanine; alpha-Synuclein; Amino Acid Sequence; Amyloid; Benzothiazoles; Binding Sites; Brain; Circular Dichroism; Congo Red; Endopeptidases; Humans; Hydrolysis; Immunohistochemistry; Lewy Bodies; Microscopy, Atomic Force; Microscopy, Polarization; Molecular Sequence Data; Mutation, Missense; Nerve Tissue Proteins; Parkinson Disease; Postmortem Changes; Proline; Protein Structure, Secondary; Recombinant Proteins; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Synucleins; Thiazoles; Threonine	2000
Ventricular cerebrospinal fluid concentrations of putative amino acid transmitters in Parkinson's disease and other disorders. Human neurobiology, 1987, Volume: 6, Issue:3 Topics: Adult; Aged; Amino Acids; Aspartic Acid; Ethanolamine; Ethanolamines; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Neurotransmitter Agents; Parkinson Disease; Proline; Tremor	1987
Hypothalamic releasing factors and Parkinson disease. Archives of neurology, 1974, Volume: 31, Issue:1 Topics: Antiparkinson Agents; Depression, Chemical; Dihydroxyphenylalanine; Drug Therapy, Combination; Glycine; Humans; Leucine; Melanocyte-Stimulating Hormones; Oligopeptides; Parkinson Disease; Pituitary Hormone-Releasing Hormones; Proline; Thyrotropin-Releasing Hormone	1974
Preliminary clinical studies with L-prolyl-L-leucyl-glycine amide in Parkinson's disease. Canadian Medical Association journal, 1972, Dec-09, Volume: 107, Issue:11 Topics: Administration, Oral; Aged; Amides; Antiparkinson Agents; Dihydroxyphenylalanine; Female; Glycine; Humans; Injections, Intravenous; Leucine; Male; Middle Aged; Movement Disorders; Parkinson Disease; Peptides; Proline	1972
DOPA and amino acid levels in plasma and cerebrospinal fluid of patients with Parkinson's disease before and during treatment with L-DOPA. Clinica chimica acta; international journal of clinical chemistry, 1973, May-18, Volume: 45, Issue:3 Topics: Administration, Oral; Adult; Aged; Amino Acids; Animals; Autoanalysis; Child; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Fasting; Female; Humans; Injections, Intraperitoneal; Male; Methionine; Middle Aged; Parkinson Disease; Proline; Rats; Time Factors	1973
Hypoprolinemia in Parkinsonism: a case report. Experientia, 1971, Volume: 27, Issue:8 Topics: Aged; Amino Acids; Humans; Male; Parkinson Disease; Proline	1971