proline has been researched along with Disease Exacerbation in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.79) | 18.2507 |
| 2000's | 18 (32.14) | 29.6817 |
| 2010's | 31 (55.36) | 24.3611 |
| 2020's | 6 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Abreu, P; Baniecki, M; Bao, W; Damle, B; Gardner, A; Hammond, J; Hendrick, VM; Leister-Tebbe, H; Pypstra, R; Rusnak, JM; Simón-Campos, A; Wisemandle, W | 1 |
| Berg, T; Boeker, KHW; Buggisch, P; C-Registry, GH; Günther, R; Hinrichsen, H; Klinker, H; Manns, MP; Mauss, S; Müller, T; Serfert, Y; Wiegand, J; Zeuzem, S | 1 |
| Cao, Y; Chen, C; Liu, N; Liu, S; Liu, Y; Mao, C; Ouyang, L; Shi, Y; Tang, H; Tao, Y; Wang, M; Wang, X; Xiao, D; Yan, Q | 1 |
| Angel, PM; Ball, LE; Bethard, JR; Drake, RR; Hughes-Halbert, C; Jefferson, M; Spruill, L | 1 |
| Bani-Sadr, F; Bourlière, M; Carrat, F; Chalouni, M; de Ledinghen, V; Dorival, C; Esterle, L; Fontaine, H; Lacombe, K; Larrey, D; Marc-Lacombe, J; Pol, S; Salmon, D; Sogni, P; Wittkop, L; Zucman, D | 1 |
| Cui, H; Erlandsson, A; Falk, A; Jäntti, M; Kukkonen, JP; Myöhänen, T; Rinne, MK; Rostami, J | 1 |
| Chen, B; Liang, H; Lu, J; Shao, Z; Wang, X; Wu, A; Zeng, G; Zhang, C; Zhang, X | 1 |
| Amemiya, M; Hayashi, N; Koshima, Y; Kuriyama, S; Matsuyama, M; Morisawa, N; Satoh, JI; Yokoo, T | 1 |
| Brooks, AJ; Chhabra, Y; Kragelund, BB; Meunier, FA; Nikolajsen, LF; Papadopulos, A; Smith, AG; Steinocher, H; Tunny, KA; Waters, MJ; Wong, HY | 1 |
| Brennan, RG; Jasser, SA; Myers, JN; Sano, D; Xie, TX; Zhao, M; Zhou, G | 1 |
| Hashemi, M; Heidari, Z; Mahmoudzadeh-Sagheb, H; Rigi-Ladiz, MA | 1 |
| Banterla, F; Bossi, A; Chianca, A; Donadelli, R; Galbusera, M; Gastoldi, S; Gherardi, G; Haefliger, C; Iliev, I; Noris, M; Parvanova, A; Remuzzi, G; Ruggenenti, P; Rurali, E; Trevisan, R | 1 |
| Blázquez-Pérez, A; Mar, J; San Miguel, R | 1 |
| Galle, PR; Grambihler, A; Kittner, JM; Koch, S; Schattenberg, JM; Schuchmann, M; Thieringer, F; Weinmann, A; Weiss, NM; Wiltink, J; Zimmermann, T | 1 |
| Hattori, M; Horiguchi, T; Iwashita, H; Matsumoto, Y; Nakamura, K; Obayashi, Y; Onishi, T; Yano, T | 1 |
| Adam, V; Cernei, N; Eckschlager, T; Gumulec, J; Heger, Z; Hrabec, R; Kizek, R; Masarik, M; Zitka, O | 1 |
| Alves, K; Barnard, R; Howe, AY; Howe, J; Long, J; Nickle, D; Thompson, S; Wahl, J | 1 |
| Aliani, M; House, JD; Mayengbam, S; Raposo, S | 1 |
| Gerlei, Z; Gervain, J; Horváth, G; Hunyady, B; Lengyel, G; Makara, M; Pár, A; Rókusz, L; Szalay, F; Telegdy, L; Tornai, I; Werling, K | 1 |
| Athanasakis, K; Ferrante, SA; Hill, M; Kyriopoulos, II; Kyriopoulos, J; Petrakis, I; Retsa, MP | 1 |
| Gissel, C; Götz, G; Mahlich, J; Repp, H | 1 |
| Bo, L; Chen, X; Jin, F; Li, C; Liu, Q; Liu, W; Xu, D | 1 |
| Bao, RF; Cao, Y; Chen, L; Hu, YP; Jiang, L; Li, HF; Liang, HB; Liu, SB; Liu, YB; Ma, Q; Shu, YJ; Wang, XA; Wang, Z; Xu, Y; Zhang, F; Zhang, YC; Zhang, YJ; Zhao, S; Zhou, J | 1 |
| Gonzalez, YS; Johnson, S; Juday, T; Misurski, D; Parisé, H; Saab, S; Virabhak, S; Wang, A | 1 |
| Heger, E; Inden, S; Kaiser, R; Kalaghatgi, P; Knops, E; Neumann-Fraune, M; Schübel, N; Sierra, S | 1 |
| Cui, J; Du, G; Hu, Y; Li, A; Liu, Y; Qin, X; Qu, T; Tong, J | 1 |
| Campagna, G; Grilli, A; La Fratta, I; Pesce, M; Rizzuto, A; Tatangelo, R | 1 |
| Connelly, KA; Gilbert, RE; Kapus, A; Kepecs, D; Thai, K; Wu, X; Zhang, Y | 1 |
| Horiguchi, N; Hosonuma, K; Kakizaki, S; Kobayashi, T; Kusano, M; Ohnishi, H; Okamoto, H; Sato, K; Takakusagi, S; Yamada, M; Yamazaki, Y | 1 |
| Amadori, D; Bonafe, M; Brigliadori, G; Fabbri, F; Gusolfino, D; Massa, I; Passardi, A; Ricci, M; Rosetti, M; Sansone, P; Storci, G; Tesei, A; Ulivi, P; Vannini, I; Zoli, W | 1 |
| Ahronowitz, I; Chang, Z; Guo, CL; MacCollin, M; Nunes, FP; Stemmer-Rachamimov, AO | 1 |
| Du, L; Lin, R; Liu, Q; Meng, K; Pan, C; Wu, W; Zhao, L | 1 |
| Acosta, ML; Christie, DL; Fletcher, EL; Kalloniatis, M; Ready, S; Shin, YS | 1 |
| Baker, KM; Chigurupati, S; Gupta, S; Kumar, R; Kumar, S; Sen, S; Seqqat, R; Young, D | 1 |
| Kamyshova, ES; Kutyrina, IM; Nosikov, VV; Shestakov, AE; Shvetsov, MIu | 1 |
| Roche, B; Samuel, D | 1 |
| Ford, JA; Greanya, E; Partovi, N; Wilby, KJ; Yoshida, EM | 1 |
| Naggie, S; Sulkowski, MS | 1 |
| Mayer, KH; Swan, T; Taylor, LE | 1 |
| Contractor, R; Dedhia, P; Dinshaw, K; Khan, Z; Saranath, D; Sharma, B; Shrivastava, S; Tandle, AT | 1 |
| Harada, R; Kobayashi, M; Nakata, H; Taguchi, H; Uemura, Y | 1 |
| Ancochea, J; Campistol, JM; Inigo, P; Lario, S; Marin-Arguedas, A; Morell, F; Mullol, J; Picado, C; Rodriguez-Arias, JM; Rodriguez-Becerra, E; Ruiz-Manzano, J; Sanz, S; Xaubet, A | 1 |
| Bojesen, SE; Nordestgaard, BG; Tybjaerg-Hansen, A | 1 |
| Whyte, MK | 1 |
| Alcocer-Varela, J; Díaz de León, L; Krötzsch, E; Zurita-Salinas, CS | 1 |
| Dowjat, WK; Kuchna, I; Wegiel, J; Wisniewski, T | 1 |
| Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW | 3 |
| Blakemore, AI; El Nahas, AM; Khalil, MS | 1 |
| Lee, WJ; Yi, SY | 1 |
| Chandoga, J; Petrovic, R; Sutovský, S; Turcáni, P | 1 |
| Osterman, A; Richardson, AD; Smith, JW; Yang, C | 1 |
| Braulke, T; Gal, A; Kossow, K; Meyer, A; Mühlhausen, C; Muschol, N; Steglich, C; Ullrich, K | 1 |
| Ho, YS; Lee, TT; Ni, MH; Tsen, TZ; Yang, CC; Yang, SD; Yu, JS | 1 |
| Karvonen, MK; Kauhanen, J; Koulu, M; Lakka, HM; Lakka, TA; Nyyssönen, K; Pesonen, U; Salonen, JT; Salonen, R; Tuomainen, TP; Uusitupa, MI; Valkonen, VP | 1 |
6 review(s) available for proline and Disease Exacerbation
| Article | Year |
|---|---|
[Hepatitis C: diagnosis, anti-viral therapy, after-care. Hungarian consensus guideline].
Topics: Antiviral Agents; Consensus; Disease Progression; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Hepatitis C; Humans; Hungary; Insurance Coverage; Insurance, Health; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Liver Failure; Liver Neoplasms; Oligopeptides; Polyethylene Glycols; Proline; Protease Inhibitors; Recombinant Proteins; Registries; Ribavirin; Treatment Outcome | 2015 |
The progression of coeliac disease: its neurological and psychiatric implications.
Topics: Adult; Celiac Disease; Cognitive Dysfunction; Diet, Gluten-Free; Disease Progression; Edible Grain; Environment; Female; Genetic Predisposition to Disease; Glutamine; Humans; Immune System Diseases; Immunity; Male; Mental Disorders; Middle Aged; Nervous System Diseases; Plant Proteins; Proline | 2017 |
Hepatitis C virus treatment pre- and post-liver transplantation.
Topics: Antiviral Agents; Disease Progression; Drug Administration Schedule; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver Cirrhosis; Liver Transplantation; Oligopeptides; Polyethylene Glycols; Postoperative Complications; Proline; Recombinant Proteins; Recurrence; Ribavirin; Serine Proteinase Inhibitors; Time Factors; Viral Load | 2012 |
Review of boceprevir and telaprevir for the treatment of chronic hepatitis C.
Topics: Antiviral Agents; Disease Management; Disease Progression; Drug Interactions; Drug Therapy, Combination; Genome, Viral; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Oligopeptides; Polyethylene Glycols; Proline; Recombinant Proteins; Ribavirin; Standard of Care; Treatment Outcome; Viral Load | 2012 |
Management of patients coinfected with HCV and HIV: a close look at the role for direct-acting antivirals.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Coinfection; Deoxycytidine; Dideoxynucleosides; Disease Progression; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Emtricitabine; Hepatitis C, Chronic; HIV Infections; Homosexuality, Male; Humans; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Diseases; Male; Oligopeptides; Organophosphonates; Polyethylene Glycols; Proline; Pyrrolidinones; Raltegravir Potassium; Recombinant Proteins; Ribavirin; Serine Proteinase Inhibitors; Substance Abuse, Intravenous; Tenofovir; Treatment Outcome | 2012 |
HIV coinfection with hepatitis C virus: evolving epidemiology and treatment paradigms.
Topics: Antiviral Agents; Coinfection; Disease Progression; Hepacivirus; Hepatitis C, Chronic; HIV; HIV Infections; Humans; Incidence; Liver Cirrhosis; Mass Screening; Proline; Risk-Taking; RNA, Viral; Sexual Behavior | 2012 |
2 trial(s) available for proline and Disease Exacerbation
| Article | Year |
|---|---|
Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19.
Topics: Administration, Oral; Adult; Antiviral Agents; COVID-19 Drug Treatment; Disease Progression; Double-Blind Method; Hospitalization; Humans; Lactams; Leucine; Nitriles; Proline; Ritonavir; SARS-CoV-2; Treatment Outcome; Vaccination; Viral Load; Viral Protease Inhibitors | 2022 |
Long-term follow-up of patients receiving boceprevir for treatment of chronic hepatitis C.
Topics: Antiviral Agents; Disease Progression; Drug Resistance, Viral; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Mutation; Phenotype; Proline; Recurrence; Treatment Failure | 2015 |
48 other study(ies) available for proline and Disease Exacerbation
| Article | Year |
|---|---|
Hepatitis C therapy with direct antiviral agents in patients with advanced chronic kidney disease: real-world experience of the German Hepatitis C-Registry (Deutsches Hepatitis C-Register).
Topics: 2-Naphthylamine; Acute Disease; Adult; Aged; Anemia; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Disease Progression; Drug Therapy, Combination; Female; Fluorenes; Germany; Glomerular Filtration Rate; Hepatitis C, Chronic; Humans; Hypertension; Imidazoles; Lactams, Macrocyclic; Liver Cirrhosis; Macrocyclic Compounds; Male; Middle Aged; Pleural Effusion; Proline; Pyrrolidines; Registries; Renal Insufficiency, Chronic; Ribavirin; Ritonavir; RNA, Viral; Severity of Illness Index; Simeprevir; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Uracil; Uridine Monophosphate; Valine | 2019 |
Cancer progression is mediated by proline catabolism in non-small cell lung cancer.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Disease Progression; Humans; Lung Neoplasms; Mice; Proline; Transfection | 2020 |
Zonal regulation of collagen-type proteins and posttranslational modifications in prostatic benign and cancer tissues by imaging mass spectrometry.
Topics: Aged; Amino Acid Sequence; Autoantigens; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Collagen Type IV; Collagen Type VIII; Collagen Type XVII; Disease Progression; Fibrillar Collagens; Humans; Hydroxylation; Male; Middle Aged; Neoplasm Proteins; Non-Fibrillar Collagens; Proline; Prostate; Prostatectomy; Prostatic Neoplasms; Protein Processing, Post-Translational; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared | 2020 |
Increased mortality in HIV/HCV-coinfected compared to HCV-monoinfected patients in the DAA era due to non-liver-related death.
Topics: Antiviral Agents; Cause of Death; Disease Progression; Female; France; Hepacivirus; Hepatitis C, Chronic; HIV; HIV Infections; Humans; Liver Cirrhosis; Male; Middle Aged; Mortality; Oligopeptides; Proline; Substance-Related Disorders; Sustained Virologic Response | 2021 |
Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells.
Topics: alpha-Synuclein; Astrocytes; Autophagy; Cell Line, Tumor; Cells, Cultured; Disease Progression; Humans; Neurons; Parkinson Disease; Proline; Prolyl Oligopeptidases; Serine Proteinase Inhibitors | 2020 |
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
Topics: Animals; Disease Progression; Extracellular Matrix; Inflammation; Interleukin-1beta; Intervertebral Disc Degeneration; Male; Molecular Docking Simulation; NF-kappa B; Phosphatidylinositol 3-Kinases; Proline; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Effectiveness of a fixed combination formula of ombitasvir/paritaprevir/ritonavir for hepatitis C virus infection in patients on maintenance haemodialysis.
Topics: Aged; Aged, 80 and over; Anilides; Antiviral Agents; Carbamates; Cyclopropanes; Disease Progression; Drug Combinations; Drug Compounding; Female; Genotype; Hepacivirus; Hepatitis C; Humans; Japan; Lactams, Macrocyclic; Liver Cirrhosis; Macrocyclic Compounds; Male; Middle Aged; Proline; Renal Dialysis; Renal Insufficiency, Chronic; Ritonavir; RNA, Viral; Sulfonamides; Sustained Virologic Response; Time Factors; Treatment Outcome; Valine; Viral Load | 2017 |
A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Cohort Studies; Computational Biology; Disease Progression; DNA Mutational Analysis; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lung; Lung Neoplasms; Magnetic Resonance Spectroscopy; Male; Mice; Phosphorylation; Polymorphism, Single Nucleotide; Proline; Protein Binding; Protein Domains; Proteolysis; Signal Transduction; Suppressor of Cytokine Signaling Proteins; Threonine; Ubiquitin-Protein Ligases; Ubiquitination | 2018 |
Serine substitution of proline at codon 151 of TP53 confers gain of function activity leading to anoikis resistance and tumor progression of head and neck cancer cells.
Topics: Animals; Anoikis; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Codon; Disease Progression; DNA, Neoplasm; Head and Neck Neoplasms; Mice; Mice, Nude; Mutation; Neoplasms, Experimental; Proline; Reverse Transcriptase Polymerase Chain Reaction; Serine; Squamous Cell Carcinoma of Head and Neck; Tumor Suppressor Protein p53 | 2013 |
Quantitative analysis of interdental Gingiva in patients with chronic periodontitis and transforming growth factor-β1 29C/T gene polymorphisms.
Topics: Adult; Alleles; Azo Compounds; Case-Control Studies; Chronic Periodontitis; Collagen; Coloring Agents; Connective Tissue; Cytosine; Disease Progression; Eosine Yellowish-(YS); Epithelium; Extracellular Matrix; Female; Genotype; Gingiva; Humans; Leucine; Male; Methyl Green; Microvessels; Middle Aged; Polymorphism, Genetic; Proline; Thymine; Transforming Growth Factor beta1 | 2014 |
ADAMTS13 predicts renal and cardiovascular events in type 2 diabetic patients and response to therapy.
Topics: ADAM Proteins; ADAMTS13 Protein; Aged; Alanine; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Female; Genotype; Humans; Kidney Failure, Chronic; Male; Middle Aged; Polymorphism, Single Nucleotide; Predictive Value of Tests; Proline; Proteolysis; Risk Assessment; Risk Factors; von Willebrand Factor | 2013 |
Cost-effectiveness analysis of triple therapy with protease inhibitors in treatment-naive hepatitis C patients.
Topics: Age Factors; Antiviral Agents; Clinical Trials as Topic; Cost-Benefit Analysis; Disease Progression; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Markov Chains; Middle Aged; Oligopeptides; Polyethylene Glycols; Proline; Protease Inhibitors; Quality-Adjusted Life Years; Recombinant Proteins; Ribavirin; Spain | 2013 |
Defer or treat? Reasons for treatment decisions in patients with chronic hepatitis C genotype 1 in the early era of directly acting antiviral agents.
Topics: Adult; Aged; Antiviral Agents; Cohort Studies; Decision Making; Disease Progression; Drug Carriers; Drug Discovery; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Logistic Models; Male; Middle Aged; Multivariate Analysis; Oligopeptides; Patient Preference; Polyethylene Glycols; Proline; Prospective Studies; Ribavirin; Severity of Illness Index; Time Factors; Watchful Waiting | 2014 |
Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice.
Topics: Age Factors; Animals; Axonal Transport; Cognition Disorders; Disease Progression; Exploratory Behavior; Gene Expression Regulation; Humans; Maze Learning; Mice; Mice, Transgenic; Motor Activity; Mutation; Nerve Tissue Proteins; Phosphorylation; Proline; Recognition, Psychology; Serine; tau Proteins | 2014 |
Determination of common urine substances as an assay for improving prostate carcinoma diagnostics.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Biomarkers, Tumor; Chromatography, Liquid; Disease Progression; Humans; Male; Middle Aged; Proline; Prostate-Specific Antigen; Prostatic Neoplasms; Sarcosine; Uric Acid | 2014 |
Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulfuration pathway in moderately vitamin B₆ deficient rats.
Topics: Animals; Asymptomatic Diseases; Biomarkers; Cystathionine; Cystathionine gamma-Lyase; Diet; Disease Models, Animal; Disease Progression; Flax; Homocysteine; Hyperhomocysteinemia; Liver; Male; Non-alcoholic Fatty Liver Disease; Proline; Pyridoxal Phosphate; Pyridoxine; Random Allocation; Rats, Sprague-Dawley; Seeds; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
Boceprevir for Chronic Genotype 1 Hepatitis C Virus in the Current Health Care Setting in Greece: A Cost-effectiveness Analysis.
Topics: Antiviral Agents; Cost-Benefit Analysis; Disease Progression; Drug Costs; Drug Therapy, Combination; Genotype; Greece; Health Care Costs; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Life Expectancy; Markov Chains; Models, Econometric; Polyethylene Glycols; Proline; Quality-Adjusted Life Years; Recombinant Proteins; Ribavirin; Sensitivity and Specificity | 2015 |
Cost-effectiveness of Interferon-free therapy for Hepatitis C in Germany--an application of the efficiency frontier approach.
Topics: Antiviral Agents; Cost-Benefit Analysis; Disease Progression; Drug Costs; Drug Therapy, Combination; Female; Genotype; Germany; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver Cirrhosis; Male; Proline; Ribavirin; Simeprevir; Sofosbuvir; Treatment Outcome | 2015 |
Activation of TRPV1-dependent calcium oscillation exacerbates seawater inhalation-induced acute lung injury.
Topics: Actin Cytoskeleton; Acute Lung Injury; Administration, Inhalation; Animals; Calcium; Calcium Chelating Agents; Calcium Signaling; Capsaicin; Cell Line, Tumor; Cytosol; Disease Progression; Egtazic Acid; Extracellular Space; Fluorescence; Humans; Inflammation Mediators; Interleukin-1beta; Lung; Male; NF-kappa B; Phosphorylation; Proline; Rats, Sprague-Dawley; Seawater; Thiocarbamates; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2016 |
The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Disease Progression; ErbB Receptors; Female; Gallbladder Neoplasms; Humans; Male; Mice; Mice, Nude; Mutation; Neoplasm Invasiveness; Neoplasm Transplantation; Prognosis; Proline; Protein Binding; Signal Transduction; Survival Analysis; Thiazoles | 2016 |
Cost-Effectiveness of Genotype 1 Chronic Hepatitis C Virus Treatments in Patients Coinfected with Human Immunodeficiency Virus in the United States.
Topics: 2-Naphthylamine; Adult; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Cost-Benefit Analysis; Cyclopropanes; Disease Progression; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Lactams, Macrocyclic; Liver Cirrhosis; Liver Neoplasms; Macrocyclic Compounds; Markov Chains; Middle Aged; Polyethylene Glycols; Proline; Quality-Adjusted Life Years; Recombinant Proteins; Ribavirin; Ritonavir; Sofosbuvir; Sulfonamides; United States; Uracil; Valine | 2016 |
HCV Resistance Profile Evolution in a GT1b, DAA-Naive Patient Before, On, and After Failing Triple DAA Therapy.
Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carbamates; Cyclopropanes; Disease Progression; Drug Combinations; Drug Resistance, Viral; Hepacivirus; Hepatitis C, Chronic; High-Throughput Nucleotide Sequencing; Humans; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Proline; Ribavirin; Ritonavir; RNA, Viral; Sulfonamides; Sustained Virologic Response; Treatment Failure; Uracil; Valine; Viral Nonstructural Proteins | 2017 |
NMR-based metabonomics and correlation analysis reveal potential biomarkers associated with chronic atrophic gastritis.
Topics: 3-Hydroxybutyric Acid; Animals; Arginine; Biomarkers; Body Weight; Chronic Disease; Disease Progression; Fatty Acids; Gastritis, Atrophic; Glucose; Immune System; Inflammation; Intestinal Mucosa; Ketoglutaric Acids; Lipids; Magnetic Resonance Spectroscopy; Male; Metabolomics; Multivariate Analysis; Oxidative Stress; Pepsin A; Proline; Rats; Rats, Sprague-Dawley; ROC Curve | 2017 |
Sirtuin 1 Activation Reduces Transforming Growth Factor-β1-Induced Fibrogenesis and Affords Organ Protection in a Model of Progressive, Experimental Kidney and Associated Cardiac Disease.
Topics: Acetylation; Anilides; Animals; Biopsy; Blood Pressure; Collagen; Disease Models, Animal; Disease Progression; Feeding Behavior; Fibrosis; Gene Expression Regulation; Genes, Reporter; Glomerulosclerosis, Focal Segmental; Heart Diseases; Heart Function Tests; HEK293 Cells; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Proline; Rats, Inbred F344; Renal Insufficiency, Chronic; RNA, Messenger; Sirtuin 1; Smad3 Protein; Thiazoles; Transforming Growth Factor beta1 | 2017 |
Combination Therapy with Ombitasvir/Paritaprevir/Ritonavir for Dialysis Patients Infected with Hepatitis C Virus: A Prospective Multi-Institutional Study.
Topics: Aged; Anilides; Carbamates; Cyclopropanes; Demography; Disease Progression; Drug Resistance, Viral; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Proline; Renal Dialysis; Ritonavir; Sulfonamides; Valine | 2017 |
Role of p53 codon 72 arginine allele in cell survival in vitro and in the clinical outcome of patients with advanced breast cancer.
Topics: Adult; Aged; Alleles; Arginine; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Codon; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Hypoxia; Kaplan-Meier Estimate; Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Proline; Transfection; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
A role for the p53 pathway in the pathology of meningiomas with NF2 loss.
Topics: Aged; Arginine; Cohort Studies; Confidence Intervals; Disease Progression; DNA Mutational Analysis; Female; Humans; Loss of Heterozygosity; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neurofibromatosis 2; Odds Ratio; Polymorphism, Genetic; Proline; Retrospective Studies; Signal Transduction; Tumor Suppressor Protein p53 | 2009 |
Hypoxia activates heparanase expression in an NF-kappaB dependent manner.
Topics: Antioxidants; Disease Progression; Enzyme Activation; Extracellular Matrix; Glucuronidase; Hypoxia; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; Oligonucleotides, Antisense; Oxygen; Proline; RNA, Messenger; Thiocarbamates; Time Factors | 2010 |
Retinal metabolic state of the proline-23-histidine rat model of retinitis pigmentosa.
Topics: Adenosine Triphosphate; Age Factors; Animals; Apoptosis; Ca(2+) Mg(2+)-ATPase; Coumaric Acids; Creatine; Creatine Kinase; Disease Models, Animal; Disease Progression; Energy Metabolism; Histidine; L-Lactate Dehydrogenase; Membrane Transport Proteins; Monocarboxylic Acid Transporters; Mutation; Phosphocreatine; Phosphodiesterase Inhibitors; Piperazines; Proline; Purines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Retina; Retinitis Pigmentosa; Sensory Rhodopsins; Sildenafil Citrate; Sodium-Potassium-Exchanging ATPase; Sulfones | 2010 |
Inhibition of nuclear factor κB regresses cardiac hypertrophy by modulating the expression of extracellular matrix and adhesion molecules.
Topics: Animals; Antioxidants; Cardiomegaly; Cell Adhesion Molecules; Disease Progression; Drug Evaluation, Preclinical; Extracellular Matrix Proteins; Female; Gene Expression Regulation; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Transgenic; NF-kappa B; Proline; Thiocarbamates | 2011 |
[Association of gene TP53 polymorphic marker Pro72Arg with clinical characteristics of chronic glomerulonephritis].
Topics: Adolescent; Adult; Aged; Alleles; Amino Acid Substitution; Arginine; Chronic Disease; Disease Progression; Female; Genetic Markers; Glomerulonephritis; Humans; Male; Middle Aged; Proline; Tumor Suppressor Protein p53; Young Adult | 2011 |
HPV16/18 prevalence in cervical lesions/cancers and p53 genotypes in cervical cancer patients from India.
Topics: Arginine; Carcinoma, Squamous Cell; Cervix Uteri; Disease Progression; DNA, Viral; Female; Genotype; Humans; India; Papillomaviridae; Papillomavirus Infections; Polymerase Chain Reaction; Polymorphism, Genetic; Prevalence; Proline; Tumor Suppressor Protein p53; Tumor Virus Infections; Uterine Cervical Neoplasms; White People | 2002 |
Cyclooxygenase-2 inhibitor NS-398 suppresses cell growth and constitutive production of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells.
Topics: Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Progression; Drug Screening Assays, Antitumor; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-1; Isoenzymes; Lung Neoplasms; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Proteins; NF-kappa B; Nitrobenzenes; Proline; Prostaglandin-Endoperoxide Synthases; Pyridines; Recombinant Proteins; Sulfonamides; Thiocarbamates; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Transforming growth factor-beta1 gene polymorphisms are associated with disease progression in idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Base Sequence; Chi-Square Distribution; Codon; Confidence Intervals; Disease Progression; Female; Follow-Up Studies; Gene Frequency; Genotype; Humans; Linear Models; Male; Oxygen; Polymorphism, Genetic; Proline; Pulmonary Alveoli; Pulmonary Fibrosis; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Integrin beta3 Leu33Pro homozygosity and risk of cancer.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Animals; Cytosine; Denmark; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genotype; Humans; Incidence; Integrin beta3; Leucine; Male; Middle Aged; Neoplasm Invasiveness; Neoplasms; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proline; Proportional Hazards Models; Prospective Studies; Registries; Risk Assessment; Risk Factors; Thymine | 2003 |
Genetic factors in idiopathic pulmonary fibrosis: transforming growth factor-beta implicated at last.
Topics: Animals; Codon; Disease Models, Animal; Disease Progression; Exons; Humans; Polymorphism, Genetic; Proline; Pulmonary Fibrosis; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Collagen turnover is diminished by different clones of skin fibroblasts from early- but not late-stage systemic sclerosis.
Topics: Adult; Age of Onset; Carbon Radioisotopes; Cell Division; Cells, Cultured; Clone Cells; Collagen; Collagen Type I; Collagen Type III; Disease Progression; Down-Regulation; Female; Fibroblasts; Gelatinases; Humans; Male; Middle Aged; Proline; Scleroderma, Systemic; Skin; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2004 |
A novel highly pathogenic Alzheimer presenilin-1 mutation in codon 117 (Pro117Ser): Comparison of clinical, neuropathological and cell culture phenotypes of Pro117Leu and Pro117Ser mutations.
Topics: Adult; Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Protein Precursor; Animals; Brain; Cell Line, Tumor; Codon; Disease Progression; Female; Gene Expression; Genotype; Humans; Male; Membrane Proteins; Mice; Middle Aged; Mutation, Missense; Neurites; Neuroblastoma; Neurofibrillary Tangles; Neurologic Examination; Pedigree; Phenotype; Presenilin-1; Proline; Serine; Transfection; Tumor Cells, Cultured | 2004 |
In vivo antitumor effect of ascorbic acid, lysine, proline and green tea extract on human colon cancer cell HCT 116 xenografts in nude mice: evaluation of tumor growth and immunohistochemistry.
Topics: Animals; Antioxidants; Ascorbic Acid; Colonic Neoplasms; Diet; Disease Progression; Immunohistochemistry; Ki-67 Antigen; Lysine; Male; Matrix Metalloproteinases; Mice; Mice, Nude; Mucins; Neoplasms, Experimental; Proline; Tea; Transplantation, Heterologous; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2005 |
Transforming growth factor-beta1 SNPs: genetic and phenotypic correlations in progressive kidney insufficiency.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Case-Control Studies; Cytosine; Disease Progression; Female; Fibrosis; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glomerulosclerosis, Focal Segmental; Haplotypes; Homozygote; Humans; Immunohistochemistry; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Proline; Severity of Illness Index; Staining and Labeling; Thymine; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
In vitro and in vivo antitumorigenic activity of a mixture of lysine, proline, ascorbic acid, and green tea extract on human breast cancer lines MDA-MB-231 and MCF-7.
Topics: Animals; Antioxidants; Ascorbic Acid; Collagen; Disease Progression; Drug Combinations; Drug Synergism; Female; Humans; Immunoenzyme Techniques; In Vitro Techniques; Laminin; Lysine; Mammary Neoplasms, Experimental; Matrix Metalloproteinases; Mice; Mice, Nude; Proline; Proteoglycans; Tea; Transplantation, Heterologous; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2005 |
Antitumor effect of ascorbic acid, lysine, proline, arginine, and green tea extract on bladder cancer cell line T-24.
Topics: Antioxidants; Arginine; Ascorbic Acid; Biomarkers, Tumor; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Disease Progression; Female; Humans; In Vitro Techniques; Lysine; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Plant Extracts; Proline; Urinary Bladder Neoplasms | 2006 |
A p53 genetic polymorphism of gastric cancer: difference between early gastric cancer and advanced gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Disease Progression; DNA, Neoplasm; Female; Genotype; Humans; Korea; Male; Middle Aged; Neoplasm Staging; Polymorphism, Genetic; Proline; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2006 |
Adult onset cerebral form of X-linked adrenoleukodystrophy with dementia of frontal lobe type with new L160P mutation in ABCD1 gene.
Topics: Adrenoleukodystrophy; Adult; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Dementia; Disease Progression; DNA Mutational Analysis; Family Health; Female; Follow-Up Studies; Humans; Leucine; Magnetic Resonance Imaging; Male; Mutation; Proline | 2007 |
Central carbon metabolism in the progression of mammary carcinoma.
Topics: Antineoplastic Agents; Breast Neoplasms; Carbon; Cell Line, Tumor; Disease Progression; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glucose; Humans; Lactates; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neoplasm Metastasis; Proline; Time Factors | 2008 |
The mutation p.Ser298Pro in the sulphamidase gene (SGSH) is associated with a slowly progressive clinical phenotype in mucopolysaccharidosis type IIIA (Sanfilippo A syndrome).
Topics: Adolescent; Adult; Child; Child, Preschool; Disease Progression; Female; Genotype; Humans; Hydrolases; Infant; Infant, Newborn; Male; Mucopolysaccharidosis III; Mutation; Phenotype; Proline; Serine | 2008 |
Association of protein kinase FA/GSK-3alpha (a proline-directed kinase and a regulator of protooncogenes) with human cervical carcinoma dedifferentiation/progression.
Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Cell Differentiation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Humans; Immunoblotting; Molecular Sequence Data; Neoplasm Invasiveness; Precipitin Tests; Proline; Proto-Oncogenes; Reference Values; Uterine Cervical Neoplasms | 1995 |
Leucine7 to proline7 polymorphism in the preproneuropeptide Y is associated with the progression of carotid atherosclerosis, blood pressure and serum lipids in Finnish men.
Topics: Adult; Blood Pressure; Carotid Artery Diseases; Disease Progression; Finland; Humans; Leucine; Lipids; Male; Middle Aged; Neuropeptide Y; Polymorphism, Genetic; Proline; Protein Precursors; Risk Factors | 2001 |