proline and Degenerative Diseases, Central Nervous System

proline has been researched along with Degenerative Diseases, Central Nervous System in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (33.33)29.6817
2010's6 (40.00)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
He, J; He, Y; Li, M; Liu, M; Sun, Z; Yang, J1
Deshmukh, L; Elias, RD; Ghirlando, R; Hammond, JA; Shihora, A1
Bravo-Arredondo, JM; Falk, AS; Langen, R; Pacheco, S; Siemer, AB; Varkey, J1
Alexey, UA; Alexey, VV; Boris, LV; Kristina, SN; Lyudmila, AA; Maxim, DE; Nikolay, MF; Valery, RV; Valery, SP; Vladimir, FM; Yuriy, DA1
Gynther, M; Jaako, K; Jalkanen, AJ; Natunen, TA; Rostalski, H1
Funayama, M; Hattori, N; Li, Y; Matsuura, E; Nishioka, K; Takanashi, M; Takashima, H; Tsuyama, S; Yoshino, H1
Becker, S; Bibow, S; Biernat, J; Blackledge, M; Gajda, M; Jaremko, L; Jaremko, M; Jensen, MR; Mandelkow, E; Ozenne, V; Schwalbe, M; Zweckstetter, M1
Chen, SH; Hong, JS; Kadiiska, MB; Kalyanaraman, B; Kumar, A; Mason, RP; Zielonka, J1
Hardy, JA; Velázquez-Delgado, EM1
Britschgi, M; Johns, H; Masliah, E; Rockenstein, E; Takeda-Uchimura, Y; Wyss-Coray, T1
Collins, P; McMahon, G; O'Connor, B1
Goh, CP; Hou, Z; Lim, AC; Qi, RZ1
Desai, PV; Shanti, ND; Shashikumar, KC1
Aghajanov, M; Bosker, F; Gladkevich, A; Korf, J; Vahradyan, H; Yenkoyan, K1
Zimecki, M1

Reviews

2 review(s) available for proline and Degenerative Diseases, Central Nervous System

ArticleYear
Proline-rich polypeptides in Alzheimer's disease and neurodegenerative disorders -- therapeutic potential or a mirage?
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Oct-01, Volume: 31, Issue:7

    Topics: Alzheimer Disease; Animals; Caspases; Clinical Trials as Topic; Cognition; Crush Syndrome; Humans; Hypothalamus; Immunity; Intercellular Signaling Peptides and Proteins; Neurodegenerative Diseases; Neurotoxicity Syndromes; Oxidative Stress; Peptides; Pituitary Gland; Proline

2007
A proline-rich polypeptide from ovine colostrum: colostrinin with immunomodulatory activity.
    Advances in experimental medicine and biology, 2008, Volume: 606

    Topics: Animals; Clinical Trials as Topic; Colostrum; Humans; Immunologic Factors; Intercellular Signaling Peptides and Proteins; Neurodegenerative Diseases; Peptides; Proline; Sheep

2008

Other Studies

13 other study(ies) available for proline and Degenerative Diseases, Central Nervous System

ArticleYear
Chiral Amino Acid Profiling in Serum Reveals Potential Biomarkers for Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 94, Issue:1

    Topics: Alzheimer Disease; Amino Acids; Aspartic Acid; Biomarkers; D-Aspartic Acid; Humans; Neurodegenerative Diseases; Phenylalanine; Proline; Tandem Mass Spectrometry

2023
ALS Variants of Annexin A11's Proline-Rich Domain Impair Its S100A6-Mediated Fibril Dissolution.
    ACS chemical neuroscience, 2023, 08-02, Volume: 14, Issue:15

    Topics: Amyloid; Amyotrophic Lateral Sclerosis; Annexins; Cell Cycle Proteins; Humans; Neurodegenerative Diseases; Proline; S100 Calcium Binding Protein A6; Solubility

2023
Structural Model of the Proline-Rich Domain of Huntingtin Exon-1 Fibrils.
    Biophysical journal, 2020, 11-17, Volume: 119, Issue:10

    Topics: Amyloid; Exons; Humans; Huntingtin Protein; Models, Structural; Neurodegenerative Diseases; Proline

2020
Phosphine modification of proline-glycine-proline tripeptide and study of its neuroprotective properties.
    Biochemical and biophysical research communications, 2021, 02-05, Volume: 539

    Topics: Cell Line, Tumor; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Oligopeptides; Phosphines; Proline; Protein Aggregation, Pathological

2021
Extracellular prolyl oligopeptidase derived from activated microglia is a potential neuroprotection target.
    Basic & clinical pharmacology & toxicology, 2019, Volume: 124, Issue:1

    Topics: Animals; Animals, Newborn; Cell Membrane; Cerebral Cortex; Coculture Techniques; Culture Media; Disease Models, Animal; Down-Regulation; Embryo, Mammalian; Female; Humans; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Neurodegenerative Diseases; Neurogenic Inflammation; Neurons; Neuroprotection; Primary Cell Culture; Proline; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Up-Regulation

2019
Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations.
    Acta neuropathologica communications, 2018, 10-17, Volume: 6, Issue:1

    Topics: Aged; alpha-Synuclein; Astrocytes; Autopsy; DNA-Binding Proteins; Female; Gene Expression Regulation; Histidine; Homozygote; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Parkinsonian Disorders; Proline; Protein Aggregation, Pathological; Substantia Nigra; tau Proteins

2018
Predictive atomic resolution descriptions of intrinsically disordered hTau40 and α-synuclein in solution from NMR and small angle scattering.
    Structure (London, England : 1993), 2014, Feb-04, Volume: 22, Issue:2

    Topics: Algorithms; alpha-Synuclein; Humans; Intrinsically Disordered Proteins; Magnetic Resonance Spectroscopy; Membrane Proteins; Neurodegenerative Diseases; Proline; Protein Folding; Protein Structure, Tertiary; Scattering, Radiation

2014
Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells.
    Free radical biology & medicine, 2014, Volume: 73

    Topics: Acetophenones; Amidines; Animals; Antioxidants; Benzylamines; Boronic Acids; Cell Line, Transformed; Coumarins; Enzyme Inhibitors; Free Radicals; Imidazoles; Lipopolysaccharides; Metalloporphyrins; Mice; Microglia; Neurodegenerative Diseases; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Proline; Pyridines; RNA Interference; RNA, Small Interfering; Spin Trapping; Thiocarbamates

2014
Phosphorylation regulates assembly of the caspase-6 substrate-binding groove.
    Structure (London, England : 1993), 2012, Apr-04, Volume: 20, Issue:4

    Topics: Apoptosis; Binding Sites; Caspase 6; Crystallography, X-Ray; Escherichia coli; Humans; Models, Molecular; Molecular Mimicry; Neurodegenerative Diseases; Phosphorylation; Proline; Protein Binding; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Repressor Proteins; Serine; Signal Transduction

2012
Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice.
    Journal of neuroinflammation, 2012, Sep-18, Volume: 9

    Topics: Animals; Brain; CD59 Antigens; Disease Models, Animal; Green Fluorescent Proteins; Humans; Leucine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Phosphorylation; Proline; Receptors, Complement; Signal Transduction; tau Proteins; Tauopathies

2012
Characterisation of the active site of a newly-discovered and potentially significant post-proline cleaving endopeptidase called ZIP using LC-UV-MS.
    The Analyst, 2003, Volume: 128, Issue:6

    Topics: Carrier Proteins; Chromatography, Liquid; Neurodegenerative Diseases; Proline; Spectrophotometry, Ultraviolet

2003
Protein kinase CK2 is an inhibitor of the neuronal Cdk5 kinase.
    The Journal of biological chemistry, 2004, Nov-05, Volume: 279, Issue:45

    Topics: Animals; Binding Sites; Casein Kinase II; Catalytic Domain; Cell Line, Tumor; Chromatography; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Humans; Immunoprecipitation; Mass Spectrometry; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Phosphorylation; Plasmids; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; RNA Interference; RNA, Small Interfering; Transfection

2004
Influence of proline on rat brain activities of alanine aminotransferase, aspartate aminotransferase and acid phosphatase.
    Neurochemical research, 2004, Volume: 29, Issue:12

    Topics: Acid Phosphatase; Alanine Transaminase; Animals; Aspartate Aminotransferases; Behavior, Animal; Brain; Brain Chemistry; Cytosol; Mitochondria; Neurodegenerative Diseases; Neurons; Proline; Rats; Subcellular Fractions

2004