Compounds > proline

proline and Deficiency of GP 2b 3a Complex

proline has been researched along with Deficiency of GP 2b 3a Complex in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amano, T; Fujita, T; Hayashi, T; Nakayama, M; Tanaka, S; Tani, Y; Yoshimura, K1
Bron, N; Gouon, V; Guinet, JM; Kieffer, N; Melchior, C; Michels, S1
Aurousseau, MH; Jallu, V; Kaplan, C; Kieffer, N; Melchior, C; Morel-Kopp, MC; Peyruchaud, O; Proulle, V1
Bellucci, S; Caen, J; Gruel, Y; Pacouret, G1
Chen, F; Coller, BS; French, DL; Grimaldi, CM; Weiss, HJ; Wu, C1
Kestin, AS; Newman, PJ; Ward, CM1
Combrié, R; Gauthier, B; Kunicki, T; Nurden, AT; Nurden, P; Pasquet, JM; Ruan, J1
Caen, JP; Chen, YP; Cieutat, AM; Djaffar, I; Pidard, D; Rosa, JP; Steiner, B1

Other Studies

8 other study(ies) available for proline and Deficiency of GP 2b 3a Complex

ArticleYear
Double heterozygosity for a novel missense mutation of Ile304 to Asn in addition to the missense mutation His280 to Pro in the integrin beta3 gene as a cause of the absence of platelet alphaIIbbeta3 in Glanzmann's thrombasthenia.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:1

    Topics: Adult; Animals; Asparagine; Blotting, Western; COS Cells; DNA Primers; DNA, Complementary; Exons; Female; Flow Cytometry; Genetic Vectors; Heterozygote; Histidine; Humans; Immunoprecipitation; Integrin beta3; Isoleucine; Male; Mutation, Missense; Pedigree; Platelet Glycoprotein GPIIb-IIIa Complex; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proline; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Thrombasthenia; Transfection

2005
Serine 752 in the cytoplasmic domain of the beta 3 integrin subunit is not required for alpha v beta 3 postreceptor signaling events.
    Cell adhesion and communication, 1996, Volume: 4, Issue:1

    Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens, CD; Cell Adhesion; CHO Cells; Cricetinae; Cytoskeleton; Extracellular Matrix Proteins; Fibrinogen; Genetic Complementation Test; Humans; Integrin beta3; Molecular Sequence Data; Oligopeptides; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Point Mutation; Proline; Protein Binding; Receptors, Vitronectin; Recombinant Fusion Proteins; Sequence Alignment; Serine; Signal Transduction; Thrombasthenia; Transfection; Vitronectin; von Willebrand Factor

1996
A three amino acid deletion in glycoprotein IIIa is responsible for type I Glanzmann's thrombasthenia: importance of residues Ile325Pro326Gly327 for beta3 integrin subunit association.
    Blood, 1997, Jul-15, Volume: 90, Issue:2

    Topics: Algeria; Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; CHO Cells; Consanguinity; Cricetinae; DNA Primers; Female; France; Glycine; Humans; Infant; Integrin beta3; Isoleucine; Male; Pedigree; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proline; Recombinant Proteins; Sequence Deletion; Thrombasthenia; Transfection

1997
Severe proximal deep vein thrombosis in a Glanzmann thrombasthenia variant successfully treated with a low molecular weight heparin.
    Blood, 1997, Jul-15, Volume: 90, Issue:2

    Topics: Aged; Anticoagulants; Femoral Vein; Genetic Variation; Heparin, Low-Molecular-Weight; Humans; Male; Platelet Glycoprotein GPIIb-IIIa Complex; Point Mutation; Popliteal Vein; Proline; Serine; Thrombasthenia; Thrombosis

1997
Glycoprotein IIb Leu214Pro mutation produces glanzmann thrombasthenia with both quantitative and qualitative abnormalities in GPIIb/IIIa.
    Blood, 1998, Mar-01, Volume: 91, Issue:5

    Topics: Animals; Bleeding Time; Blood Platelets; CHO Cells; Cricetinae; Dual Specificity Phosphatase 2; Fibrinogen; Humans; Immunosorbent Techniques; Leucine; Male; Middle Aged; Mutation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Proline; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Thrombasthenia; Transfection

1998
A Leu262Pro mutation in the integrin beta(3) subunit results in an alpha(IIb)-beta(3) complex that binds fibrin but not fibrinogen.
    Blood, 2000, Jul-01, Volume: 96, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antigens, CD; Cell Line; Child, Preschool; COS Cells; Female; Fibrin; Fibrinogen; Humans; Integrin beta3; Kidney; Leucine; Male; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Pedigree; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Point Mutation; Polymerase Chain Reaction; Proline; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Thrombasthenia; Transfection; Xenopus

2000
A novel 196Leu to Pro substitution in the beta3 subunit of the alphaIIbbeta3 integrin in a patient with a variant form of Glanzmann thrombasthenia.
    Platelets, 2002, Volume: 13, Issue:2

    Topics: Aged; Amino Acid Substitution; DNA Mutational Analysis; Family Health; Fibrinogen; Genetic Variation; Humans; Leucine; Male; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Proline; Protein Binding; Protein Subunits; Thrombasthenia

2002
Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-01, Volume: 89, Issue:21

    Topics: Amino Acid Sequence; Antibodies, Monoclonal; Base Sequence; Chromatography, Affinity; Female; Fibrinogen; Genetic Variation; Humans; Macromolecular Substances; Male; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Pedigree; Platelet Activation; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Proline; RNA, Messenger; Serine; Thrombasthenia

1992