proline has been researched along with DDPAC in 9 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 5 (55.56) | 24.3611 |
2020's | 4 (44.44) | 2.80 |
Authors | Studies |
---|---|
Aburas, J; Brown, AEX; Fleming, AC; Gao, FB; Gendron, TF; Ghadge, G; Gu, Y; Islam, P; Kankel, MW; Kiskinis, E; Kratsios, P; Krishnan, G; Roos, RP; Sonobe, Y; Warren, EC | 1 |
Fairman, R; Lee, EB; Nelson, SCK; Viera Ortiz, AP; Zhang, Y | 1 |
Babu, M; Becker, S; de Opakua, AI; Favretto, F; Rankovic, M; Zweckstetter, M | 1 |
Blair, IP; Cain, AK; Fat, SCM; Fifita, JA; Grima, N; Henden, L; Heng, B; Hogan, AL; Lee, A; Maharjan, R; McCann, EP; Morsch, M; Rayner, S; Tarr, I; Williams, KL; Wright, A; Wu, S; Yang, S; Zhang, KY; Zhang, ZH; Zhao, Q | 1 |
Huang, YR; Ji, M; Liu, DQ; Liu, RT; Wang, SW; Xie, XX; Yu, XL; Zhang, LX; Zhang, Y | 1 |
Hattori, S; Matsuoka, M; Shibagaki, Y; Suzuki, H | 1 |
Barroso, C; Coelho, M; de Mendonça, A; Duyckaerts, C; Martins, M; Miltenberger-Miltenyi, G; Pimentel, J; Pires, C; Valadas, A; Verdelho, A | 1 |
Ichida, JK; Krishnamurthy, K; Lin, S; Markandaiah, SS; Monaghan, J; Pandey, UB; Pasinelli, P; Shi, Y; Shneider, NA; Tan, W; Trotti, D; Wen, X; Westergard, T | 1 |
Abdelkarim, S; Adamson, G; Clark, CN; Clarke, J; Fisher, EM; Fox, NC; Fratta, P; Howard, R; Lu, CH; Malaspina, A; Mead, S; Morgan, S; Orrell, R; Pittman, A; Plagnol, V; Rohrer, JD; Rossor, MN; Sharma, N; Sidle, K; Warren, JD | 1 |
9 other study(ies) available for proline and DDPAC
Article | Year |
---|---|
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Caenorhabditis elegans; Dipeptides; Female; Frontotemporal Dementia; Gene Editing; Gene Knockdown Techniques; Glycine; HEK293 Cells; Humans; Middle Aged; Motor Neurons; Nerve Degeneration; Proline | 2021 |
C9orf72 proline-arginine dipeptide repeats disrupt the proteasome and perturb proteolytic activities.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Dipeptides; DNA Repeat Expansion; Drosophila melanogaster; Frontotemporal Dementia; Humans; Proline; Proteasome Endopeptidase Complex; Proteolysis | 2023 |
Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Arginine; Biopolymers; Brain; C9orf72 Protein; Catalytic Domain; Crystallography, X-Ray; Dipeptides; DNA Repeat Expansion; Frontotemporal Dementia; Humans; Nuclear Magnetic Resonance, Biomolecular; Peptidylprolyl Isomerase; Proline; Protein Aggregates; Protein Binding; Protein Folding; Recombinant Proteins; Repetitive Sequences, Amino Acid | 2021 |
Splicing factor proline and glutamine rich intron retention, reduced expression and aggregate formation are pathological features of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Glutamine; Humans; Introns; Motor Neurons; Proline; RNA Splicing Factors | 2021 |
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Alzheimer's disease and frontotemporal dementia.
Topics: Alzheimer Disease; Animals; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Immunologic; Exploratory Behavior; Female; Frontotemporal Dementia; Hepatitis B Vaccines; Immunization; Immunodominant Epitopes; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Proline; Recognition, Psychology; Serine; tau Proteins; Treatment Outcome; Vaccines, Virus-Like Particle | 2018 |
The proline-arginine repeat protein linked to C9-ALS/FTD causes neuronal toxicity by inhibiting the DEAD-box RNA helicase-mediated ribosome biogenesis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Arginine; C9orf72 Protein; Cell Line, Tumor; Cell Survival; DEAD-box RNA Helicases; Dipeptides; Frontotemporal Dementia; HEK293 Cells; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Microsatellite Repeats; Neurons; Proline; Ribosomes; RNA, Ribosomal | 2018 |
Phenotypic variability of familial and sporadic Progranulin p.Gln257Profs*27 mutation.
Topics: Aged; DNA Mutational Analysis; Family Health; Female; Frontotemporal Dementia; Glutamine; Humans; Intercellular Signaling Peptides and Proteins; Magnetic Resonance Imaging; Mental Status Schedule; Middle Aged; Mutation; Phenotype; Progranulins; Proline | 2013 |
Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death.
Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Antisense Elements (Genetics); Arginine; C9orf72 Protein; Cell Death; Dipeptides; DNA Repeat Expansion; Drosophila melanogaster; Frontotemporal Dementia; Humans; Motor Neurons; Neurons; Primary Cell Culture; Proline; Protein Aggregation, Pathological; Proteins; Spinal Cord | 2014 |
CHCHD10 Pro34Ser is not a highly penetrant pathogenic variant for amyotrophic lateral sclerosis and frontotemporal dementia.
Topics: Amyotrophic Lateral Sclerosis; Cohort Studies; Frontotemporal Dementia; Genetic Variation; Humans; Mitochondrial Proteins; Mutation; Penetrance; Proline; Serine | 2016 |